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Isochorismate synthase entC 2-succinyl-5- enolpyruvyl- 6-hydroxy-3- cyclohexene- 1-carboxylate synthase 2-succinyl-6- hydroxy-2,4- cyclohexadiene- 1-carboxylate synthase o- succinylbenzoate synthase 2- succinylbenzoate- -CoA ligase Naphthoate synthase 1,4- dihydroxy-2- naphthoyl-CoA thioesterase 1,4- dihydroxy-2- naphthoate octaprenyltransferase Ubiquinone/menaquinone biosynthesis methyltransferase ubiE 1,4- dihydroxy-2- naphthoate octaprenyltransferase Hydrogenase-1 small chain Hydrogenase-1 large chain Probable Ni/Fe- hydrogenase 1 B-type cytochrome subunit Chorismate isochorismate Oxoglutaric acid H+ CO2 2-succinyl-5- enolpyruvyl- 6-hydroxy-3- cyclohexene- 1-carboxylate (1R,6R)-6- hydroxy-2- succinylcyclohexa- 2,4-diene-1- carboxylate Pyruvic acid 2- succinylbenzoate H2O CoA ATP 2- Succinylbenzoyl- CoA PPi AMP H+ H2O 1,4- dihydroxy-2- naphthoyl-CoA H2O CoA H+ 1,4- dihydroxy-2- naphthoate Octaprenyl diphosphate H+ CO2 PPi 2- Demethylmenaquinol 8 S- Adenosylmethionine H+ S- Adenosylhomocysteine Menaquinol 8 H+ Farnesylfarnesylgeranyl- PP CO2 PPi H+ Hydrogen 2- Demethylmenaquinone 8 H+
entC menD menH menC menE menB menI menA ubiE menA hyaA hyaB hyaC Chorismate isochorismate Oxoglutaric acid Hydrogen Ion Carbon dioxide 2-succinyl-5- enolpyruvyl- 6-hydroxy-3- cyclohexene- 1-carboxylate (1R,6R)-6- hydroxy-2- succinylcyclohexa- 2,4-diene-1- carboxylate Pyruvic acid 2- succinylbenzoate Water Coenzyme A Adenosine triphosphate 2- Succinylbenzoyl- CoA Pyrophosphate Adenosine monophosphate Hydrogen Ion Water 1,4- dihydroxy-2- naphthoyl-CoA Water Coenzyme A Hydrogen Ion 1,4- dihydroxy-2- naphthoate Octaprenyl diphosphate Hydrogen Ion Carbon dioxide Pyrophosphate 2- Demethylmenaquinol 8 S- Adenosylmethionine Hydrogen Ion S- Adenosylhomocysteine Menaquinol 8 Hydrogen Ion Farnesylfarnesylgeranyl- PP Carbon dioxide Pyrophosphate Hydrogen Ion Hydrogen 2- Demethylmenaquinone 8 Hydrogen Ion