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Serine Biosynthesis and Metabolism SubPathway 6022 PubChem-compound C23H38N7O17P3S Acetyl-CoA 809.1258 C4H4O5 Oxalacetic acid 132.00587 Malate synthase G 937 ChemSpider C00311 KEGG Compound Aconitate hydratase 1 Succinic acid CHEBI:30797 ChEBI NADH cis-Aconitic acid 439153 PubChem-compound 1.0 SMILES O CIT BioCyc Acetyl-CoA HMDB0000094 HMDB Reaction2588 false Acetyl-CoA + Oxalacetic acid + Water → Citric acid + Coenzyme A + Hydrogen Ion LEFT_TO_RIGHT 1.0 473-81-4 CAS P0AC35 UniProt HMDB0000538 HMDB NAD OXALACETIC_ACID BioCyc ATP BioCyc 1122 PubChem-compound 6816 PubChem-compound 328-42-7 CAS SMILES O[C@@H](CC(O)=O)C(O)=O CHEBI:15846 ChEBI ADP BioCyc SMP0002035 SMPDB 388334 ChemSpider C6H8O7 Isocitric acid 192.02701 1.0 NADH 5742 ChemSpider 1038 PubChem-compound Uncharacterized protein ybhJ GO:0005829 GENE ONTOLOGY 4.2.1.3 false 4.2.1.3 Water + cis-Aconitic acid ↔ Isocitric acid REVERSIBLE Reaction5877 false Water + cis-Aconitic acid ↔ Citric acid REVERSIBLE ReactionCatalysis2558 ACTIVATION Malate synthase G 4.2.1.32 false 4.2.1.32 Tartaric acid → Oxalacetic acid + Water LEFT_TO_RIGHT 1.1.1.83 false 1.1.1.83 NAD + Tartaric acid ↔ 2-Hydroxy-3-oxosuccinate + Hydrogen Ion + NADH REVERSIBLE 274 ChemSpider P36683 UniProt 392277 ChemSpider 2.0 97-67-6 CAS 1.0 CHEBI:16908 ChEBI Isocitrate lyase CHEBI:32398 ChEBI Oxalacetic acid Acetyl-CoA 704 ChemSpider 945 ChemSpider 1010 ChemSpider 558863 ChemSpider 77-92-9 CAS 1.0 SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS CHEBI:30769 ChEBI CHEBI:30887 ChEBI 2.0 1.0 1.0 643757 PubChem-compound Hydrogen Ion PW000785 PathWhiz 1.0 1161 ChemSpider Cytosol Glyceric acid Glyoxylate carboligase L-Malic acid 1.0 C00597 KEGG Compound SUC BioCyc 58-68-4 CAS HMDB0001423 HMDB 124-38-9 CAS PW000779 PathWhiz C2H2O3 Glyoxylic acid 74.0004 C00008 KEGG Compound 1.0 P77161 UniProt Hydrogen Ion C00001 KEGG Compound 439194 PubChem-compound 1.0 Tartaric acid C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1.0 L(+)-tartrate dehydratase subunit alpha HMDB0000223 HMDB D-malate dehydrogenase [decarboxylating] 87-69-4 CAS Glycolysis and Pyruvate Dehydrogenase SubPathway 1.0 CHEBI:15741 ChEBI Coenzyme A C21H28N7O14P2 NAD 664.11694 TCA Cycle SubPathway C00011 KEGG Compound SMILES O=C=O PW002021 PathWhiz C00010 KEGG Compound HMDB0000902 HMDB C00258 KEGG Compound 1110 PubChem-compound Glyoxylic acid P25516 UniProt 1.0 C21H29N7O14P2 NADH 665.12476 HMDB0001206 HMDB 5957 PubChem-compound GO:0005620 GENE ONTOLOGY C4H6O4 Succinic acid 118.02661 L(+)-tartrate dehydratase subunit beta 562 TAXONOMY C6H6O6 cis-Aconitic acid 174.01643 320-77-4 CAS H Hydrogen Ion 1.007825 threo-d(s)-iso-citrate BioCyc C00149 KEGG Compound Uncharacterized protein ybhJ HMDB0000119 HMDB 56-65-5 CAS 53-84-9 CAS SubPathwayInteraction3059 SubPathwayReaction SubPathway3059Reaction 444305 PubChem-compound C00024 KEGG Compound Citric acid Adenosine triphosphate glyoxylate carboligase C10H15N5O10P2 Adenosine diphosphate 427.02942 SMILES OC(C(CC(O)=O)C(O)=O)C(O)=O SubPathwayInteraction3061 SubPathway3061Reaction SubPathwayReaction 298-12-4 CAS SubPathwayInteraction3062 SubPathwayReaction SubPathway3062Reaction SubPathwayInteraction3060 SubPathway3060Reaction SubPathwayReaction P75764 UniProt 2-Hydroxy-3-oxosuccinate Cysteine Biosynthesis SubPathway C4H4O6 2-Hydroxy-3-oxosuccinate 148.0008 C6H8O7 Citric acid 192.02701 2-hydroxy-3-oxopropionate reductase_ SMP0000802 SMPDB 1.0 P0A9G6 UniProt 524 PubChem-compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 19782904 PubChem-compound 760 PubChem-compound CHEBI:16891 ChEBI SMP0000807 SMPDB C00158 KEGG Compound C00036 KEGG Compound 5682 ChemSpider HMDB0000807 HMDB 2.3.3.9 false 2.3.3.9 Acetyl-CoA + Glyoxylic acid + Water → Coenzyme A + Hydrogen Ion + L-Malic acid LEFT_TO_RIGHT SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI HMDB0000254 HMDB SMILES OC(=O)CCC(O)=O Water 1090 ChemSpider HMDB0000139 HMDB Reaction2984 false Adenosine triphosphate + Glyceric acid → 3-Phosphoglyceric acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES OC(=O)C\C(=C\C(O)=O)C(O)=O 4.1.3.1 false 4.1.3.1 Isocitric acid ↔ Glyoxylic acid + Succinic acid REVERSIBLE 4.1.1.47 false 4.1.1.47 2 Glyoxylic acid + Hydrogen Ion → Carbon dioxide + Tartronate semialdehyde LEFT_TO_RIGHT 1.1.1.60 false 1.1.1.60 Hydrogen Ion + NADH + Tartronate semialdehyde → Glyceric acid + NAD LEFT_TO_RIGHT HMDB0001341 HMDB CO-A BioCyc P0AEP7 UniProt 222656 PubChem-compound Citrate synthase monomer C00042 KEGG Compound 72-89-9 CAS 1078 ChemSpider C00048 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O Adenosine diphosphate ReactionCatalysis2946 ACTIVATION CHEBI:15422 ChEBI SMP0000821 SMPDB C3H7O7P 3-Phosphoglyceric acid 185.99294 6557 ChemSpider C4H6O6 Tartaric acid 150.01643 ReactionCatalysis2949 ACTIVATION ReactionCatalysis2948 ACTIVATION 1.0 D-malate dehydrogenase [decarboxylating] Escherichia coli SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS 388299 ChemSpider Glyoxylic acid SMP0000829 SMPDB CHEBI:16992 ChEBI 1.0 C01146 KEGG Compound L(+)-tartrate dehydratase subunit alpha GLYOX BioCyc HMDB0000156 HMDB HMDB0001487 HMDB L(+)-tartrate dehydratase subunit beta 1.0 HMDB0006938 HMDB C3H6O4 Glyceric acid 106.02661 isocitrate lyase Aconitate hydratase 2 ReactionCatalysis2950 ACTIVATION Water NAD P76251 UniProt C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 CHEBI:16526 ChEBI HMDB0000956 HMDB 1.0 CHEBI:16761 ChEBI 305 ChemSpider 1.0 CHEBI:15671 ChEBI C3H4O4 Tartronate semialdehyde 104.010956 Aconitate hydratase 1 Glycerate kinase 2 P23524 UniProt tartrate dehydratase 1.0 CHEBI:17050 ChEBI aconitate hydratase Tartronate semialdehyde 1.0 3-Phosphoglyceric acid 962 PubChem-compound 724 PubChem-compound 392413 ChemSpider 5800 ChemSpider 6.0 1.0 SMILES OC(COP(O)(O)=O)C(O)=O CO2 Carbon dioxide 43.98983 2480-77-5 CAS 2-hydroxy-3-oxopropionate reductase_ HMDB0149325 HMDB 5893 PubChem-compound C00080 KEGG Compound 110-15-6 CAS ReactionCatalysis5845 ACTIVATION Periplasmic Space ReactionCatalysis5844 ACTIVATION Glyoxylic acid SMILES OC[C@@H](O)C(O)=O HMDB0002111 HMDB ReactionCatalysis5843 ACTIVATION ReactionCatalysis5842 ACTIVATION P05847 UniProt CHEBI:15377 ChEBI 4.0 CHEBI:15378 ChEBI SMILES [H+] Glycerate kinase 2 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O tartronate semialdehyde reductase 2 Isocitric acid citrate synthase 585-84-2 CAS 1.0 PW000809 PathWhiz G3P BioCyc 1.0 SMILES OC(C=O)C(O)=O 280 PubChem-compound Tartronate semialdehyde CHEBI:30744 ChEBI 1.0 PW000800 PathWhiz Transport444 false Glyoxylic acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT CHEBI:32805 ChEBI SMILES OC(C(O)=O)C(=O)C(O)=O C00898 KEGG Compound 444493 PubChem-compound C00417 KEGG Compound Citrate synthase monomer Isocitrate lyase 2-PG BioCyc 1198 PubChem-compound SMILES OC(=O)C=O ACETYL-COA BioCyc 1.0 H2O Water 18.010565 193317 ChemSpider HMDB0000193 HMDB HMDB0000072 HMDB P37330 UniProt NADH BioCyc 1.0 Glycolate and Glyoxylate Degradation II NAD BioCyc ReactionCatalysis3685 ACTIVATION 1.0 HMDB0059597 HMDB 4.0 CHEBI:17778 ChEBI Carbon dioxide HMDB0001967 HMDB Aconitate hydratase 2 CHEBI:15351 ChEBI CIS-ACONITATE BioCyc 970 PubChem-compound P0ABH7 UniProt 740 ChemSpider SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O Glyoxylate carboligase 85-61-0 CAS C4H6O5 L-Malic acid 134.02153 820-11-1 CAS Malate synthase G Glyoxylate carboligase 2-hydroxy-3- oxopropionate reductase_ Glycerate kinase 2 Isocitrate lyase Aconitate hydratase 2 Uncharacterized protein ybhJ Aconitate hydratase 1 Aconitate hydratase 2 Uncharacterized protein ybhJ Aconitate hydratase 1 Citrate synthase monomer L(+)-tartrate dehydratase subunit alpha L(+)-tartrate dehydratase subunit beta D-malate dehydrogenase [decarboxylating] Glyoxylic acid Glyoxylic acid Glyoxylic acid H 2 O Acetyl-CoA CoA H + L-Malic acid Glyoxylic acid H + CO 2 Tartronate semialdehyde NADH H + NAD Glyceric acid ATP ADP H + 3- Phosphoglyceric acid Isocitric acid Succinic acid H 2 O cis-Aconitic acid H 2 O Citric acid Oxalacetic acid H 2 O Acetyl-CoA CoA H + Tartaric acid H 2 O NAD NADH H + 2-Hydroxy-3- oxosuccinate Magnesium TCA Cycle Glycolysis and Pyruvate Dehydrogenase Cysteine Biosynthesis Serine Biosynthesis and Metabolism
Serine Biosynthesis and Metabolism SubPathway 6022 PubChem-compound C23H38N7O17P3S Acetyl-CoA 809.1258 C4H4O5 Oxalacetic acid 132.00587 Malate synthase G 937 ChemSpider C00311 KEGG Compound Aconitate hydratase 1 Succinic acid CHEBI:30797 ChEBI NADH cis-Aconitic acid 439153 PubChem-compound 1.0 SMILES O CIT BioCyc Acetyl-CoA HMDB0000094 HMDB Reaction2588 false Acetyl-CoA + Oxalacetic acid + Water → Citric acid + Coenzyme A + Hydrogen Ion LEFT_TO_RIGHT 1.0 473-81-4 CAS P0AC35 UniProt HMDB0000538 HMDB NAD OXALACETIC_ACID BioCyc ATP BioCyc 1122 PubChem-compound 6816 PubChem-compound 328-42-7 CAS SMILES O[C@@H](CC(O)=O)C(O)=O CHEBI:15846 ChEBI ADP BioCyc SMP0002035 SMPDB 388334 ChemSpider C6H8O7 Isocitric acid 192.02701 1.0 NADH 5742 ChemSpider 1038 PubChem-compound Uncharacterized protein ybhJ GO:0005829 GENE ONTOLOGY 4.2.1.3 false 4.2.1.3 Water + cis-Aconitic acid ↔ Isocitric acid REVERSIBLE Reaction5877 false Water + cis-Aconitic acid ↔ Citric acid REVERSIBLE ReactionCatalysis2558 ACTIVATION Malate synthase G 4.2.1.32 false 4.2.1.32 Tartaric acid → Oxalacetic acid + Water LEFT_TO_RIGHT 1.1.1.83 false 1.1.1.83 NAD + Tartaric acid ↔ 2-Hydroxy-3-oxosuccinate + Hydrogen Ion + NADH REVERSIBLE 274 ChemSpider P36683 UniProt 392277 ChemSpider 2.0 97-67-6 CAS 1.0 CHEBI:16908 ChEBI Isocitrate lyase CHEBI:32398 ChEBI Oxalacetic acid Acetyl-CoA 704 ChemSpider 945 ChemSpider 1010 ChemSpider 558863 ChemSpider 77-92-9 CAS 1.0 SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS CHEBI:30769 ChEBI CHEBI:30887 ChEBI 2.0 1.0 1.0 643757 PubChem-compound Hydrogen Ion PW000785 PathWhiz 1.0 1161 ChemSpider Cytosol Glyceric acid Glyoxylate carboligase L-Malic acid 1.0 C00597 KEGG Compound SUC BioCyc 58-68-4 CAS HMDB0001423 HMDB 124-38-9 CAS PW000779 PathWhiz C2H2O3 Glyoxylic acid 74.0004 C00008 KEGG Compound 1.0 P77161 UniProt Hydrogen Ion C00001 KEGG Compound 439194 PubChem-compound 1.0 Tartaric acid C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1.0 L(+)-tartrate dehydratase subunit alpha HMDB0000223 HMDB D-malate dehydrogenase [decarboxylating] 87-69-4 CAS Glycolysis and Pyruvate Dehydrogenase SubPathway 1.0 CHEBI:15741 ChEBI Coenzyme A C21H28N7O14P2 NAD 664.11694 TCA Cycle SubPathway C00011 KEGG Compound SMILES O=C=O PW002021 PathWhiz C00010 KEGG Compound HMDB0000902 HMDB C00258 KEGG Compound 1110 PubChem-compound Glyoxylic acid P25516 UniProt 1.0 C21H29N7O14P2 NADH 665.12476 HMDB0001206 HMDB 5957 PubChem-compound GO:0005620 GENE ONTOLOGY C4H6O4 Succinic acid 118.02661 L(+)-tartrate dehydratase subunit beta 562 TAXONOMY C6H6O6 cis-Aconitic acid 174.01643 320-77-4 CAS H Hydrogen Ion 1.007825 threo-d(s)-iso-citrate BioCyc C00149 KEGG Compound Uncharacterized protein ybhJ HMDB0000119 HMDB 56-65-5 CAS 53-84-9 CAS SubPathwayInteraction3059 SubPathwayReaction SubPathway3059Reaction 444305 PubChem-compound C00024 KEGG Compound Citric acid Adenosine triphosphate glyoxylate carboligase C10H15N5O10P2 Adenosine diphosphate 427.02942 SMILES OC(C(CC(O)=O)C(O)=O)C(O)=O SubPathwayInteraction3061 SubPathway3061Reaction SubPathwayReaction 298-12-4 CAS SubPathwayInteraction3062 SubPathwayReaction SubPathway3062Reaction SubPathwayInteraction3060 SubPathway3060Reaction SubPathwayReaction P75764 UniProt 2-Hydroxy-3-oxosuccinate Cysteine Biosynthesis SubPathway C4H4O6 2-Hydroxy-3-oxosuccinate 148.0008 C6H8O7 Citric acid 192.02701 2-hydroxy-3-oxopropionate reductase_ SMP0000802 SMPDB 1.0 P0A9G6 UniProt 524 PubChem-compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 19782904 PubChem-compound 760 PubChem-compound CHEBI:16891 ChEBI SMP0000807 SMPDB C00158 KEGG Compound C00036 KEGG Compound 5682 ChemSpider HMDB0000807 HMDB 2.3.3.9 false 2.3.3.9 Acetyl-CoA + Glyoxylic acid + Water → Coenzyme A + Hydrogen Ion + L-Malic acid LEFT_TO_RIGHT SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI HMDB0000254 HMDB SMILES OC(=O)CCC(O)=O Water 1090 ChemSpider HMDB0000139 HMDB Reaction2984 false Adenosine triphosphate + Glyceric acid → 3-Phosphoglyceric acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES OC(=O)C\C(=C\C(O)=O)C(O)=O 4.1.3.1 false 4.1.3.1 Isocitric acid ↔ Glyoxylic acid + Succinic acid REVERSIBLE 4.1.1.47 false 4.1.1.47 2 Glyoxylic acid + Hydrogen Ion → Carbon dioxide + Tartronate semialdehyde LEFT_TO_RIGHT 1.1.1.60 false 1.1.1.60 Hydrogen Ion + NADH + Tartronate semialdehyde → Glyceric acid + NAD LEFT_TO_RIGHT HMDB0001341 HMDB CO-A BioCyc P0AEP7 UniProt 222656 PubChem-compound Citrate synthase monomer C00042 KEGG Compound 72-89-9 CAS 1078 ChemSpider C00048 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O Adenosine diphosphate ReactionCatalysis2946 ACTIVATION CHEBI:15422 ChEBI SMP0000821 SMPDB C3H7O7P 3-Phosphoglyceric acid 185.99294 6557 ChemSpider C4H6O6 Tartaric acid 150.01643 ReactionCatalysis2949 ACTIVATION ReactionCatalysis2948 ACTIVATION 1.0 D-malate dehydrogenase [decarboxylating] Escherichia coli SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS 388299 ChemSpider Glyoxylic acid SMP0000829 SMPDB CHEBI:16992 ChEBI 1.0 C01146 KEGG Compound L(+)-tartrate dehydratase subunit alpha GLYOX BioCyc HMDB0000156 HMDB HMDB0001487 HMDB L(+)-tartrate dehydratase subunit beta 1.0 HMDB0006938 HMDB C3H6O4 Glyceric acid 106.02661 isocitrate lyase Aconitate hydratase 2 ReactionCatalysis2950 ACTIVATION Water NAD P76251 UniProt C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 CHEBI:16526 ChEBI HMDB0000956 HMDB 1.0 CHEBI:16761 ChEBI 305 ChemSpider 1.0 CHEBI:15671 ChEBI C3H4O4 Tartronate semialdehyde 104.010956 Aconitate hydratase 1 Glycerate kinase 2 P23524 UniProt tartrate dehydratase 1.0 CHEBI:17050 ChEBI aconitate hydratase Tartronate semialdehyde 1.0 3-Phosphoglyceric acid 962 PubChem-compound 724 PubChem-compound 392413 ChemSpider 5800 ChemSpider 6.0 1.0 SMILES OC(COP(O)(O)=O)C(O)=O CO2 Carbon dioxide 43.98983 2480-77-5 CAS 2-hydroxy-3-oxopropionate reductase_ HMDB0149325 HMDB 5893 PubChem-compound C00080 KEGG Compound 110-15-6 CAS ReactionCatalysis5845 ACTIVATION Periplasmic Space ReactionCatalysis5844 ACTIVATION Glyoxylic acid SMILES OC[C@@H](O)C(O)=O HMDB0002111 HMDB ReactionCatalysis5843 ACTIVATION ReactionCatalysis5842 ACTIVATION P05847 UniProt CHEBI:15377 ChEBI 4.0 CHEBI:15378 ChEBI SMILES [H+] Glycerate kinase 2 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O tartronate semialdehyde reductase 2 Isocitric acid citrate synthase 585-84-2 CAS 1.0 PW000809 PathWhiz G3P BioCyc 1.0 SMILES OC(C=O)C(O)=O 280 PubChem-compound Tartronate semialdehyde CHEBI:30744 ChEBI 1.0 PW000800 PathWhiz Transport444 false Glyoxylic acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT CHEBI:32805 ChEBI SMILES OC(C(O)=O)C(=O)C(O)=O C00898 KEGG Compound 444493 PubChem-compound C00417 KEGG Compound Citrate synthase monomer Isocitrate lyase 2-PG BioCyc 1198 PubChem-compound SMILES OC(=O)C=O ACETYL-COA BioCyc 1.0 H2O Water 18.010565 193317 ChemSpider HMDB0000193 HMDB HMDB0000072 HMDB P37330 UniProt NADH BioCyc 1.0 Glycolate and Glyoxylate Degradation II NAD BioCyc ReactionCatalysis3685 ACTIVATION 1.0 HMDB0059597 HMDB 4.0 CHEBI:17778 ChEBI Carbon dioxide HMDB0001967 HMDB Aconitate hydratase 2 CHEBI:15351 ChEBI CIS-ACONITATE BioCyc 970 PubChem-compound P0ABH7 UniProt 740 ChemSpider SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O Glyoxylate carboligase 85-61-0 CAS C4H6O5 L-Malic acid 134.02153 820-11-1 CAS glcB gcl glxR garK aceA acnB ybhJ acnA acnB ybhJ acnA gltA ttdA ttdB dmlA Glyoxylic acid Glyoxylic acid Glyoxylic acid Water Acetyl-CoA Coenzyme A Hydrogen Ion L-Malic acid Glyoxylic acid Hydrogen Ion Carbon dioxide Tartronate semialdehyde NADH Hydrogen Ion NAD Glyceric acid Adenosine triphosphate Adenosine diphosphate Hydrogen Ion 3- Phosphoglyceric acid Isocitric acid Succinic acid Water cis-Aconitic acid Water Citric acid Oxalacetic acid Water Acetyl-CoA Coenzyme A Hydrogen Ion Tartaric acid Water NAD NADH Hydrogen Ion 2-Hydroxy-3- oxosuccinate TCA Cycle Glycolysis and Pyruvate Dehydrogenase Cysteine Biosynthesis Serine Biosynthesis and Metabolism