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Amidophosphoribosyltransferase Phosphoribosylamine- -glycine ligase Phosphoribosylglycinamide formyltransferase 2 Phosphoribosylglycinamide formyltransferase Phosphoribosylformylglycinamidine synthase Phosphoribosylformylglycinamidine cyclo-ligase Phosphomethylpyrimidine synthase Thiamine- phosphate pyrophosphorylase Thiamine- monophosphate kinase Phosphoribosyl pyrophosphate H 2 O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PP i Glycine ATP N1-(5- phospho-β-D- ribosyl)glycinamide P i ADP H + ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP P i H + 10-formyl- tetrahydrofolate mono-L- glutamate H + tetrahydropteroyl mono-L- glutamate 5'- Phosphoribosyl- N- formylglycinamide H 2 O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid P i ADP H + ATP 5- Aminoimidazole ribonucleotide P i ADP H + S- Adenosylmethionine H + Carbon monoxide Formic acid L-Methionine 5'- Deoxyadenosine 4-amino-2- methyl-5- phosphomethylpyrimidine ATP ADP 4-amino-2- methyl-5- diphosphomethylpyrimidine 2-((2R,5Z)-2- Carboxy-4- methylthiazol- 5(2H)- ylidene)ethyl phosphate H + CO 2 PP i Thiamine monophosphate ATP ADP Thiamine pyrophosphate Magnesium Magnesium Potassium Magnesium NADPH NADH NADPH S- Adenosylmethionine Magnesium Magnesium Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
purF purD purT purN purL purM thiC thiE thiL Phosphoribosyl pyrophosphate Water L-Glutamine 5- Phosphoribosylamine L-Glutamic acid Pyrophosphate Glycine Adenosine triphosphate N1-(5- phospho-β-D- ribosyl)glycinamide Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate Formic acid 5'- Phosphoribosyl- N- formylglycinamide Adenosine diphosphate Phosphate Hydrogen Ion 10-formyl- tetrahydrofolate mono-L- glutamate Hydrogen Ion tetrahydropteroyl mono-L- glutamate 5'- Phosphoribosyl- N- formylglycinamide Water L-Glutamine Adenosine triphosphate 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate 5- Aminoimidazole ribonucleotide Phosphate Adenosine diphosphate Hydrogen Ion S- Adenosylmethionine Hydrogen Ion Carbon monoxide Formic acid L-Methionine 5'- Deoxyadenosine 4-amino-2- methyl-5- phosphomethylpyrimidine Adenosine triphosphate Adenosine diphosphate 4-amino-2- methyl-5- diphosphomethylpyrimidine 2-((2R,5Z)-2- Carboxy-4- methylthiazol- 5(2H)- ylidene)ethyl phosphate Hydrogen Ion Carbon dioxide Pyrophosphate Thiamine monophosphate Adenosine triphosphate Adenosine diphosphate Thiamine pyrophosphate thiD