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HMDB00012 HMDB HMDB00014 HMDB 6022 PubChem-compound HMDB01227 HMDB 66-22-8 CAS 365-07-1 CAS C00672 KEGG Compound 937 ChemSpider 1135 PubChem-compound 964-26-1 CAS SMILES O=C1NC=CC(=O)N1 1.0 Thymine HMDB01341 HMDB 1.0 SMILES O Reaction6021 false Adenosine triphosphate + Thymidine → 5-Thymidylic acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT 1.0 C10H15N2O8P 5-Thymidylic acid 322.0566 ATP BioCyc HMDB01351 HMDB HMDB00262 HMDB H4N Ammonium 18.034374 2.4.2.4 false 2.4.2.4 Deoxyuridine + Phosphate → Deoxyribose 1-phosphate + Uracil LEFT_TO_RIGHT Reaction6019 false Deoxyribose 1-phosphate + Thymine → Phosphate + Thymidine LEFT_TO_RIGHT 1.0 ADP BioCyc Reaction6014 false Deoxycytidine + Hydrogen Ion + Water → Ammonium + Deoxyuridine LEFT_TO_RIGHT 2.7.1.21 false 2.7.1.21 Adenosine triphosphate + Deoxyuridine → Adenosine diphosphate + Hydrogen Ion + dUMP LEFT_TO_RIGHT CHEBI:17568 ChEBI C9H13N3O4 Deoxycytidine 227.0906 C9H12N2O5 Deoxyuridine 228.07462 1.0 Thymidine phosphorylase 5742 ChemSpider 5-Thymidylic acid 1038 PubChem-compound 1.0 C00214 KEGG Compound 1141 ChemSpider GO:0005829 GENE ONTOLOGY SMILES O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O HMDB59597 HMDB 1.0 DUMP BioCyc Transport499 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport498 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Deoxyuridine C00106 KEGG Compound O4P Phosphate 94.95342 1010 ChemSpider HMDB41827 HMDB 439287 PubChem-compound THYMIDINE BioCyc CHEBI:17821 ChEBI Ammonium Hydrogen Ion SMILES NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1 SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O Cytosol 1.0 218 ChemSpider Adenosine triphosphate C5H11O7P Deoxyribose 1-phosphate 214.02425 cytidine deaminase SMILES [O-]P([O-])([O-])=O 1.0 13118 ChemSpider 13117 ChemSpider Cytidine deaminase C00009 KEGG Compound C00008 KEGG Compound Hydrogen Ion 50-89-5 CAS 9319 ChemSpider C00001 KEGG Compound C00364 KEGG Compound thymidine phosphorylase / uracil phosphorylase DEOXY-RIBOSE-1P BioCyc CHEBI:18367 ChEBI 1032 ChemSpider P0AFF2 UniProt C00002 KEGG Compound C00365 KEGG Compound HMDB01429 HMDB 1.0 P23331 UniProt C01342 KEGG Compound CHEBI:28938 ChEBI P0AFF4 UniProt Deoxyribose 1-phosphate 5957 PubChem-compound C5H6N2O2 Thymine 126.04293 GO:0005620 GENE ONTOLOGY H Hydrogen Ion 1.007825 P07650 UniProt 58574 ChemSpider 56-65-5 CAS 388420 ChemSpider CHEBI:17013 ChEBI Nucleoside permease nupG Adenosine diphosphate Nucleoside permease nupC C10H15N5O10P2 Adenosine diphosphate 427.02942 Thymidine 2.0 HMDB01409 HMDB C10H14N2O5 Thymidine 242.09027 Transport501 false Deoxyuridine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport500 false Deoxyuridine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT CHEBI:17622 ChEBI CHEBI:17748 ChEBI Thymidine kinase CPD-8587 BioCyc 1.0 salvage pathways of pyrimidine deoxyribonucleotides Cytidine deaminase Water C9H13N2O8P dUMP 308.04095 SMILES CC1=CNC(=O)NC1=O CHEBI:15698 ChEBI HMDB00300 HMDB Uracil Deoxyuridine 65063 PubChem-compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O 14798-03-9 CAS HMDB00538 HMDB CHEBI:15422 ChEBI 1.0 URACIL BioCyc 2.0 5585 ChemSpider 7732-18-5 CAS PW002061 PathWhiz C00178 KEGG Compound SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2)C(=O)NC1=O dUMP SMILES [NH4+] 9700 PubChem-compound C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:16761 ChEBI http://identifiers.org/smpdb/SMP02073 SMPDB 962 PubChem-compound 1.0 5800 ChemSpider 13712 PubChem-compound 1174 PubChem-compound 13711 PubChem-compound CHEBI:16450 ChEBI Phosphate Nucleoside permease nupG 1.0 Nucleoside permease nupC HMDB02111 HMDB C00080 KEGG Compound Periplasmic Space 951-77-9 CAS TransportCatalysis432 ACTIVATION TransportCatalysis431 ACTIVATION TransportCatalysis430 ACTIVATION CHEBI:15377 ChEBI C00526 KEGG Compound TMP BioCyc CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS C00881 KEGG Compound Thymidine kinase 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 THYMINE BioCyc Deoxycytidine P0ABF6 UniProt Deoxyuridine ReactionCatalysis5979 ACTIVATION 1.0 1.0 ReactionCatalysis5976 ACTIVATION Deoxycytidine Thymidine phosphorylase ReactionCatalysis5975 ACTIVATION 1.0 1103 ChemSpider C4H4N2O2 Uracil 112.027275 16741146 PubChem-compound 17210-42-3 CAS HMDB00273 HMDB 951-78-0 CAS SMILES OC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O H2O Water 18.010565 ReactionCatalysis5982 ACTIVATION ReactionCatalysis5980 ACTIVATION DEOXYCYTIDINE BioCyc CHEBI:28542 ChEBI 1061 PubChem-compound 65-71-4 CAS Hydrogen Ion Deoxycytidine 5789 PubChem-compound DEOXYURIDINE BioCyc TransportCatalysis429 ACTIVATION 1.0 1.0 Nucleoside permease nupG Nucleoside permease nupC Nucleoside permease nupG Nucleoside permease nupC Cytidine deaminase Thymidine kinase Thymidine phosphorylase Thymidine phosphorylase Thymidine kinase Deoxycytidine Deoxycytidine H + H + Deoxycytidine Deoxycytidine H + H + Deoxyuridine Deoxyuridine H + H + Deoxyuridine Deoxyuridine H + H + H 2 O H + Ammonium Deoxyuridine ATP ADP H + dUMP P i Uracil Deoxyribose 1-phosphate Thymine P i Thymidine ATP ADP H + 5-Thymidylic acid dCTP Magnesium dCTP Magnesium
HMDB00012 HMDB HMDB00014 HMDB 6022 PubChem-compound HMDB01227 HMDB 66-22-8 CAS 365-07-1 CAS C00672 KEGG Compound 937 ChemSpider 1135 PubChem-compound 964-26-1 CAS SMILES O=C1NC=CC(=O)N1 1.0 Thymine HMDB01341 HMDB 1.0 SMILES O Reaction6021 false Adenosine triphosphate + Thymidine → 5-Thymidylic acid + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT 1.0 C10H15N2O8P 5-Thymidylic acid 322.0566 ATP BioCyc HMDB01351 HMDB HMDB00262 HMDB H4N Ammonium 18.034374 2.4.2.4 false 2.4.2.4 Deoxyuridine + Phosphate → Deoxyribose 1-phosphate + Uracil LEFT_TO_RIGHT Reaction6019 false Deoxyribose 1-phosphate + Thymine → Phosphate + Thymidine LEFT_TO_RIGHT 1.0 ADP BioCyc Reaction6014 false Deoxycytidine + Hydrogen Ion + Water → Ammonium + Deoxyuridine LEFT_TO_RIGHT 2.7.1.21 false 2.7.1.21 Adenosine triphosphate + Deoxyuridine → Adenosine diphosphate + Hydrogen Ion + dUMP LEFT_TO_RIGHT CHEBI:17568 ChEBI C9H13N3O4 Deoxycytidine 227.0906 C9H12N2O5 Deoxyuridine 228.07462 1.0 Thymidine phosphorylase 5742 ChemSpider 5-Thymidylic acid 1038 PubChem-compound 1.0 C00214 KEGG Compound 1141 ChemSpider GO:0005829 GENE ONTOLOGY SMILES O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O HMDB59597 HMDB 1.0 DUMP BioCyc Transport499 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport498 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Deoxyuridine C00106 KEGG Compound O4P Phosphate 94.95342 1010 ChemSpider HMDB41827 HMDB 439287 PubChem-compound THYMIDINE BioCyc CHEBI:17821 ChEBI Ammonium Hydrogen Ion SMILES NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1 SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O Cytosol 1.0 218 ChemSpider Adenosine triphosphate C5H11O7P Deoxyribose 1-phosphate 214.02425 cytidine deaminase SMILES [O-]P([O-])([O-])=O 1.0 13118 ChemSpider 13117 ChemSpider Cytidine deaminase C00009 KEGG Compound C00008 KEGG Compound Hydrogen Ion 50-89-5 CAS 9319 ChemSpider C00001 KEGG Compound C00364 KEGG Compound thymidine phosphorylase / uracil phosphorylase DEOXY-RIBOSE-1P BioCyc CHEBI:18367 ChEBI 1032 ChemSpider P0AFF2 UniProt C00002 KEGG Compound C00365 KEGG Compound HMDB01429 HMDB 1.0 P23331 UniProt C01342 KEGG Compound CHEBI:28938 ChEBI P0AFF4 UniProt Deoxyribose 1-phosphate 5957 PubChem-compound C5H6N2O2 Thymine 126.04293 GO:0005620 GENE ONTOLOGY H Hydrogen Ion 1.007825 P07650 UniProt 58574 ChemSpider 56-65-5 CAS 388420 ChemSpider CHEBI:17013 ChEBI Nucleoside permease nupG Adenosine diphosphate Nucleoside permease nupC C10H15N5O10P2 Adenosine diphosphate 427.02942 Thymidine 2.0 HMDB01409 HMDB C10H14N2O5 Thymidine 242.09027 Transport501 false Deoxyuridine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport500 false Deoxyuridine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT CHEBI:17622 ChEBI CHEBI:17748 ChEBI Thymidine kinase CPD-8587 BioCyc 1.0 salvage pathways of pyrimidine deoxyribonucleotides Cytidine deaminase Water C9H13N2O8P dUMP 308.04095 SMILES CC1=CNC(=O)NC1=O CHEBI:15698 ChEBI HMDB00300 HMDB Uracil Deoxyuridine 65063 PubChem-compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O 14798-03-9 CAS HMDB00538 HMDB CHEBI:15422 ChEBI 1.0 URACIL BioCyc 2.0 5585 ChemSpider 7732-18-5 CAS PW002061 PathWhiz C00178 KEGG Compound SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2)C(=O)NC1=O dUMP SMILES [NH4+] 9700 PubChem-compound C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:16761 ChEBI http://identifiers.org/smpdb/SMP02073 SMPDB 962 PubChem-compound 1.0 5800 ChemSpider 13712 PubChem-compound 1174 PubChem-compound 13711 PubChem-compound CHEBI:16450 ChEBI Phosphate Nucleoside permease nupG 1.0 Nucleoside permease nupC HMDB02111 HMDB C00080 KEGG Compound Periplasmic Space 951-77-9 CAS TransportCatalysis432 ACTIVATION TransportCatalysis431 ACTIVATION TransportCatalysis430 ACTIVATION CHEBI:15377 ChEBI C00526 KEGG Compound TMP BioCyc CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS C00881 KEGG Compound Thymidine kinase 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 THYMINE BioCyc Deoxycytidine P0ABF6 UniProt Deoxyuridine ReactionCatalysis5979 ACTIVATION 1.0 1.0 ReactionCatalysis5976 ACTIVATION Deoxycytidine Thymidine phosphorylase ReactionCatalysis5975 ACTIVATION 1.0 1103 ChemSpider C4H4N2O2 Uracil 112.027275 16741146 PubChem-compound 17210-42-3 CAS HMDB00273 HMDB 951-78-0 CAS SMILES OC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O H2O Water 18.010565 ReactionCatalysis5982 ACTIVATION ReactionCatalysis5980 ACTIVATION DEOXYCYTIDINE BioCyc CHEBI:28542 ChEBI 1061 PubChem-compound 65-71-4 CAS Hydrogen Ion Deoxycytidine 5789 PubChem-compound DEOXYURIDINE BioCyc TransportCatalysis429 ACTIVATION 1.0 1.0 nupG nupC nupG nupC cdd tdk deoA deoA tdk Deoxycytidine Deoxycytidine Hydrogen Ion Hydrogen Ion Deoxycytidine Deoxycytidine Hydrogen Ion Hydrogen Ion Deoxyuridine Deoxyuridine Hydrogen Ion Hydrogen Ion Deoxyuridine Deoxyuridine Hydrogen Ion Hydrogen Ion Water Hydrogen Ion Ammonium Deoxyuridine Adenosine triphosphate Adenosine diphosphate Hydrogen Ion dUMP Phosphate Uracil Deoxyribose 1-phosphate Thymine Phosphate Thymidine Adenosine triphosphate Adenosine diphosphate Hydrogen Ion 5-Thymidylic acid