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2.0 6022 PubChem-compound a biotinylated [BCCP dimer] Biotinylated [BCCP monomer] 769 PubChem-compound C23H38N7O17P3S Acetyl-CoA 809.1258 carboxylated-biotinylated [BCCP dimer] 937 ChemSpider CPD-8587 BioCyc AMP BioCyc Water 2.0 Biotin carboxyl carrier protein of acetyl-CoA carboxylase Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta SMILES O CHEBI:15956 ChEBI C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate HMDB0000250 HMDB 1.0 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS HMDB0001341 HMDB CHEBI:16027 ChEBI HMDB0000538 HMDB ATP BioCyc 58-85-5 CAS 72-89-9 CAS C00288 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 1.0 559142 ChemSpider SMILES OC([O-])=O ADP BioCyc 2.0 10213 ChemSpider P24182 UniProt CHEBI:15422 ChEBI PW002067 PathWhiz Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha 2.0 1.0 HCO3 BioCyc Bifunctional protein BirA 1.0 Escherichia coli 5742 ChemSpider 1038 PubChem-compound 524-14-1 CAS SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS Biotin-Carboxyl Carrying Protein 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 Biotin carboxylase Adenosine monophosphate 6.4.1.2 false 6.4.1.2 Adenosine diphosphate + Hydrogen Ion + Malonyl-CoA + Phosphate + a biotinylated [BCCP dimer] ← Acetyl-CoA + Adenosine triphosphate + Water + carboxylated-biotinylated [BCCP dimer] RIGHT_TO_LEFT Reaction6044 false Adenosine triphosphate + Hydrogen carbonate + a biotinylated [BCCP dimer] → Adenosine diphosphate + Hydrogen Ion + Phosphate + carboxylated-biotinylated [BCCP dimer] LEFT_TO_RIGHT P0A9Q5 UniProt HMDB0000030 HMDB Biotin-Carboxyl Carrier Protein Assembly 5858 ChemSpider C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 Reaction6041 false Adenosine triphosphate + Biotin + Biotin-Carboxyl Carrying Protein → Adenosine monophosphate + Biotinylated [BCCP monomer] + Hydrogen Ion + Pyrophosphate LEFT_TO_RIGHT Reaction6042 true Biotinylated [BCCP monomer] → a biotinylated [BCCP dimer] LEFT_TO_RIGHT O4P Phosphate 94.95342 Acetyl-CoA 1010 ChemSpider CHEBI:16761 ChEBI Biotin 1.0 HMDB0000045 HMDB 171548 PubChem-compound PPI BioCyc ReactionCatalysis6008 ACTIVATION C10H16N2O3S Biotin 244.08817 ReactionCatalysis6007 ACTIVATION ReactionCatalysis6006 ACTIVATION 962 PubChem-compound 1.0 CHEBI:17544 ChEBI Hydrogen Ion 5800 ChemSpider 392413 ChemSpider Phosphate 1.0 Adenosine triphosphate P0ABD5 UniProt C00080 KEGG Compound P0ABD8 UniProt 1.0 SMILES [O-]P([O-])([O-])=O 1.0 Biotin-Carboxyl Carrying Protein acetyl-CoA carboxylase C00083 KEGG Compound Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HMDB0002111 HMDB Biotin carboxyl carrier protein of acetyl-CoA carboxylase C00009 KEGG Compound CHEBI:15531 ChEBI CHEBI:15377 ChEBI C00008 KEGG Compound C24H38N7O19P3S Malonyl-CoA 853.1156 CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS 58-64-0 CAS HMDB0001429 HMDB C00001 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O BIOTIN BioCyc 2.0 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha C00120 KEGG Compound CHEBI:18361 ChEBI Biotinylated [BCCP monomer] a biotinylated [BCCP dimer] Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta carboxylated-biotinylated [BCCP dimer] CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound 149962 ChemSpider SMILES [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2 1.0 P06709 UniProt Bifunctional protein BirA 1.0 SMP0002079 SMPDB 644102 PubChem-compound 444493 PubChem-compound 6083 PubChem-compound O00763 UniProt acetyl-CoA carboxyltransferase Malonyl-CoA C00013 KEGG Compound 10663 PubChem-compound O7P2 Pyrophosphate 173.91193 HMDB0000595 HMDB ACETYL-COA BioCyc H2O Water 18.010565 5957 PubChem-compound HMDB0001206 HMDB 562 TAXONOMY H Hydrogen Ion 1.007825 1061 PubChem-compound HMDB0059597 HMDB 56-65-5 CAS 749 ChemSpider C00020 KEGG Compound 71-52-3 CAS B1IQF6 UniProt CHEBI:15351 ChEBI Biotin carboxylase SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O C00024 KEGG Compound Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 Hydrogen carbonate 1.0 1.0 CHO3 Hydrogen carbonate 60.99257 MALONYL-COA BioCyc HMDB0001175 HMDB biotin- [acetyl-CoA carboxylase] synthetase Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta Biotin carboxylase Biotin carboxyl carrier protein of acetyl-CoA carboxylase Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta ATP Biotin H + AMP PP i ATP HCO 3 - H + ADP P i H + P i ADP Malonyl-CoA H 2 O Acetyl-CoA ATP Biotin-Carboxyl Carrying Protein Biotinylated [BCCP monomer] a biotinylated [BCCP dimer] carboxylated- biotinylated [BCCP dimer] a biotinylated [BCCP dimer]
2.0 6022 PubChem-compound a biotinylated [BCCP dimer] Biotinylated [BCCP monomer] 769 PubChem-compound C23H38N7O17P3S Acetyl-CoA 809.1258 carboxylated-biotinylated [BCCP dimer] 937 ChemSpider CPD-8587 BioCyc AMP BioCyc Water 2.0 Biotin carboxyl carrier protein of acetyl-CoA carboxylase Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta SMILES O CHEBI:15956 ChEBI C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate HMDB0000250 HMDB 1.0 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS HMDB0001341 HMDB CHEBI:16027 ChEBI HMDB0000538 HMDB ATP BioCyc 58-85-5 CAS 72-89-9 CAS C00288 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 1.0 559142 ChemSpider SMILES OC([O-])=O ADP BioCyc 2.0 10213 ChemSpider P24182 UniProt CHEBI:15422 ChEBI PW002067 PathWhiz Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha 2.0 1.0 HCO3 BioCyc Bifunctional protein BirA 1.0 Escherichia coli 5742 ChemSpider 1038 PubChem-compound 524-14-1 CAS SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS Biotin-Carboxyl Carrying Protein 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 Biotin carboxylase Adenosine monophosphate 6.4.1.2 false 6.4.1.2 Adenosine diphosphate + Hydrogen Ion + Malonyl-CoA + Phosphate + a biotinylated [BCCP dimer] ← Acetyl-CoA + Adenosine triphosphate + Water + carboxylated-biotinylated [BCCP dimer] RIGHT_TO_LEFT Reaction6044 false Adenosine triphosphate + Hydrogen carbonate + a biotinylated [BCCP dimer] → Adenosine diphosphate + Hydrogen Ion + Phosphate + carboxylated-biotinylated [BCCP dimer] LEFT_TO_RIGHT P0A9Q5 UniProt HMDB0000030 HMDB Biotin-Carboxyl Carrier Protein Assembly 5858 ChemSpider C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 Reaction6041 false Adenosine triphosphate + Biotin + Biotin-Carboxyl Carrying Protein → Adenosine monophosphate + Biotinylated [BCCP monomer] + Hydrogen Ion + Pyrophosphate LEFT_TO_RIGHT Reaction6042 true Biotinylated [BCCP monomer] → a biotinylated [BCCP dimer] LEFT_TO_RIGHT O4P Phosphate 94.95342 Acetyl-CoA 1010 ChemSpider CHEBI:16761 ChEBI Biotin 1.0 HMDB0000045 HMDB 171548 PubChem-compound PPI BioCyc ReactionCatalysis6008 ACTIVATION C10H16N2O3S Biotin 244.08817 ReactionCatalysis6007 ACTIVATION ReactionCatalysis6006 ACTIVATION 962 PubChem-compound 1.0 CHEBI:17544 ChEBI Hydrogen Ion 5800 ChemSpider 392413 ChemSpider Phosphate 1.0 Adenosine triphosphate P0ABD5 UniProt C00080 KEGG Compound P0ABD8 UniProt 1.0 SMILES [O-]P([O-])([O-])=O 1.0 Biotin-Carboxyl Carrying Protein acetyl-CoA carboxylase C00083 KEGG Compound Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HMDB0002111 HMDB Biotin carboxyl carrier protein of acetyl-CoA carboxylase C00009 KEGG Compound CHEBI:15531 ChEBI CHEBI:15377 ChEBI C00008 KEGG Compound C24H38N7O19P3S Malonyl-CoA 853.1156 CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS 58-64-0 CAS HMDB0001429 HMDB C00001 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O BIOTIN BioCyc 2.0 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha C00120 KEGG Compound CHEBI:18361 ChEBI Biotinylated [BCCP monomer] a biotinylated [BCCP dimer] Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta carboxylated-biotinylated [BCCP dimer] CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound 149962 ChemSpider SMILES [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2 1.0 P06709 UniProt Bifunctional protein BirA 1.0 SMP0002079 SMPDB 644102 PubChem-compound 444493 PubChem-compound 6083 PubChem-compound O00763 UniProt acetyl-CoA carboxyltransferase Malonyl-CoA C00013 KEGG Compound 10663 PubChem-compound O7P2 Pyrophosphate 173.91193 HMDB0000595 HMDB ACETYL-COA BioCyc H2O Water 18.010565 5957 PubChem-compound HMDB0001206 HMDB 562 TAXONOMY H Hydrogen Ion 1.007825 1061 PubChem-compound HMDB0059597 HMDB 56-65-5 CAS 749 ChemSpider C00020 KEGG Compound 71-52-3 CAS B1IQF6 UniProt CHEBI:15351 ChEBI Biotin carboxylase SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O C00024 KEGG Compound Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 Hydrogen carbonate 1.0 1.0 CHO3 Hydrogen carbonate 60.99257 MALONYL-COA BioCyc HMDB0001175 HMDB birA accA accD accC accB accA accD Adenosine triphosphate Biotin Hydrogen Ion Adenosine monophosphate Pyrophosphate Adenosine triphosphate Hydrogen carbonate Hydrogen Ion Adenosine diphosphate Phosphate Hydrogen Ion Phosphate Adenosine diphosphate Malonyl-CoA Water Acetyl-CoA Adenosine triphosphate Biotin-Carboxyl Carrying Protein Biotinylated [BCCP monomer] a biotinylated [BCCP dimer] carboxylated- biotinylated [BCCP dimer] a biotinylated [BCCP dimer]