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HMDB00133 HMDB 6021 PubChem-compound 937 ChemSpider RIBOSE-1P BioCyc 3315 PubChem-compound SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=C(O)N=C2O C01762 KEGG Compound HMDB00132 HMDB Ribose 1-phosphate SMILES O C10H13N5O4 Adenosine 267.09674 1.0 CHEBI:17596 ChEBI 1.0 H4N Ammonium 18.034374 CHEBI:17111 ChEBI SMILES OC1=NC=NC2=C1NC=N2 CHEBI:16235 ChEBI Reaction6050 false Inosine + Phosphate → Hypoxanthine + Ribose 1-phosphate LEFT_TO_RIGHT C10H12N4O5 Inosine 268.08078 58484 ChemSpider 1038 PubChem-compound C00212 KEGG Compound 1.0 GO:0005829 GENE ONTOLOGY 7540-64-9 CAS 1.0 Adenosine HMDB59597 HMDB HYPOXANTHINE BioCyc XANTHINE BioCyc 3.5.4.4 false 3.5.4.4 Adenosine + Hydrogen Ion + Water → Ammonium + Inosine LEFT_TO_RIGHT P0A6K6 UniProt 1.0 Xanthosine permease 1.0 O4P Phosphate 94.95342 1.0 SMILES CC1=C(C=CC(=C1)C1=CC(C)=C(C=C1)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O 1010 ChemSpider Phosphopentomutase Adenine HMDB41827 HMDB 439167 PubChem-compound C5H5N5 Adenine 135.05449 1.0 64959 PubChem-compound 1.0 C00119 KEGG Compound C00117 KEGG Compound Ammonium 388313 ChemSpider Hydrogen Ion HMDB01548 HMDB Xanthine phosphoribosyltransferase SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1NC=NC2=O Cytosol SubPathwayInteraction3148 SubPathway3148Reaction SubPathwayReaction 218 ChemSpider 1.0 Reaction5899 false Ribose 1-phosphate → D-Ribose 5-phosphate LEFT_TO_RIGHT C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 SMILES [O-]P([O-])([O-])=O GUANOSINE BioCyc 2.4.2.1 false 2.4.2.1 Phosphate + Xanthosine → Ribose 1-phosphate + Xanthine LEFT_TO_RIGHT Reaction6066 false Adenosine + Phosphate → Adenine + Ribose 1-phosphate LEFT_TO_RIGHT C5H4N4O2 Xanthine 152.03343 SMP02088 SMPDB C00009 KEGG Compound CHEBI:15652 ChEBI HMDB01554 HMDB ADENINE BioCyc CHEBI:17712 ChEBI Hydrogen Ion 1151 ChemSpider C00001 KEGG Compound 790 PubChem-compound C00242 KEGG Compound Adenosine C34H28N6O14S4 diphosphate 872.0546 CHEBI:18367 ChEBI 1032 ChemSpider Guanine 73323 PubChem-compound 66054 ChemSpider P22333 UniProt SMILES NC1=C2NC=NC2=NC=N1 Guanosine HMDB01429 HMDB Purine nucleoside phosphorylase deoD-type 1.0 Reaction6058 false Guanosine + Phosphate → Guanine + Ribose 1-phosphate LEFT_TO_RIGHT C10H13N5O5 Guanosine 283.09167 Xanthosine phosphorylase C5H5N5O Guanine 151.04941 60961 PubChem-compound CHEBI:17368 ChEBI 1.0 GUANINE BioCyc 118-00-3 CAS C01342 KEGG Compound 6802 PubChem-compound CHEBI:28938 ChEBI 7339 PubChem-compound purine nucleoside phosphorylase P45563 UniProt 6.0 P45562 UniProt SMP00927 SMPDB P0AFF4 UniProt 1.0 Xanthine C5H11O8P Ribose 1-phosphate 230.01915 Reaction6088 false Phosphoribosyl pyrophosphate + Xanthine → Xanthylic acid + diphosphate LEFT_TO_RIGHT GO:0005620 GENE ONTOLOGY Xanthosine CHEBI:16708 ChEBI P0A9M5 UniProt Phosphoribosyl pyrophosphate CHEBI:18107 ChEBI H Hydrogen Ion 1.007825 68-94-0 CAS Xanthosine P0ABP8 UniProt 1.0 C00385 KEGG Compound xanthosine phosphorylase C00262 KEGG Compound C00147 KEGG Compound Adenosine deaminase C00387 KEGG Compound Nucleoside permease nupG Transport507 false Adenosine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT xanthine-guanine phosphoribosyltransferase Transport508 false Xanthosine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 73-24-5 CAS 764 PubChem-compound ReactionCatalysis6050 ACTIVATION CPD-8587 BioCyc 146-80-5 CAS Water CHEBI:52742 ChEBI 1.0 SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H]1O CHEBI:16300 ChEBI 5799 ChemSpider Xanthosine 1.0 PW002076 PathWhiz 768 ChemSpider Xanthosine phosphorylase 7062 ChemSpider 73-40-5 CAS C00294 KEGG Compound Purine nucleoside phosphorylase deoD-type 14798-03-9 CAS 14075-00-4 CAS 6.0 HMDB00195 HMDB 7732-18-5 CAS CHEBI:16750 ChEBI 1.0 diphosphate INOSINE BioCyc SMILES NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1 SMILES [NH4+] purine ribonucleosides degradation 1.0 6544 ChemSpider XANTHOSINE-5-PHOSPHATE BioCyc 58-61-7 CAS purine nucleotides de novo biosynthesis SubPathway C00620 KEGG Compound C10H13N4O9P Xanthylic acid 364.04202 Xanthylic acid D-Ribose 5-phosphate C5H11O8P D-Ribose 5-phosphate 230.01915 962 PubChem-compound HMDB00299 HMDB CHEBI:16335 ChEBI Adenosine deaminase HMDB00292 HMDB HMDB00050 HMDB Phosphate 1.0 Nucleoside permease nupG HMDB02111 HMDB C00080 KEGG Compound 4.0 439236 PubChem-compound Periplasmic Space TransportCatalysis439 ACTIVATION TransportCatalysis438 ACTIVATION ReactionCatalysis6014 ACTIVATION ReactionCatalysis6013 ACTIVATION ADENOSINE BioCyc CHEBI:15377 ChEBI 14265-44-2 CAS CHEBI:15378 ChEBI SMILES [H+] ReactionCatalysis6022 ACTIVATION Inosine 1.0 1.0 SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1NC(=O)NC2=O RIBOSE-5P BioCyc SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O ReactionCatalysis6028 ACTIVATION ReactionCatalysis6027 ACTIVATION HMDB00034 HMDB HMDB01489 HMDB HMDB00157 HMDB C00655 KEGG Compound C10H12N4O6 Xanthosine 284.07568 16741146 PubChem-compound 388373 ChemSpider 69-89-6 CAS PRPP BioCyc Xanthosine permease SMILES O=C1NC2=C(NC=N2)C(=O)N1 58-63-9 CAS H2O Water 18.010565 190 PubChem-compound 54923 ChemSpider SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O Adenosine PW000910 PathWhiz 1.0 ReactionCatalysis5862 ACTIVATION 1061 PubChem-compound 523-98-8 CAS Hydrogen Ion HMDB00280 HMDB Xanthine phosphoribosyltransferase Hypoxanthine 1188 PubChem-compound 744 ChemSpider SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N1 SMILES NC1=NC(=O)C2=C(N1)N=CN2 Phosphopentomutase 1.0 185 ChemSpider C5H4N4O Hypoxanthine 136.03851 4300-28-1 CAS Nucleoside permease nupG Nucleoside permease nupG Xanthosine permease Xanthosine phosphorylase Purine nucleoside phosphorylase deoD-type Purine nucleoside phosphorylase deoD-type Adenosine deaminase Purine nucleoside phosphorylase deoD-type Phosphopentomutase Xanthine phosphoribosyltransferase Adenosine Adenosine H + H + Adenosine Adenosine H + H + Xanthosine Xanthosine H + H + Xanthosine P i Xanthine Ribose 1-phosphate Adenosine P i Adenine Inosine P i Hypoxanthine Adenosine H 2 O H + Ammonium Guanosine P i Guanine D-Ribose 5-phosphate Phosphoribosyl pyrophosphate Xanthylic acid diphosphate Magnesium purine nucleotides de novo biosynthesis
HMDB00133 HMDB 6021 PubChem-compound 937 ChemSpider RIBOSE-1P BioCyc 3315 PubChem-compound SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=C(O)N=C2O C01762 KEGG Compound HMDB00132 HMDB Ribose 1-phosphate SMILES O C10H13N5O4 Adenosine 267.09674 1.0 CHEBI:17596 ChEBI 1.0 H4N Ammonium 18.034374 CHEBI:17111 ChEBI SMILES OC1=NC=NC2=C1NC=N2 CHEBI:16235 ChEBI Reaction6050 false Inosine + Phosphate → Hypoxanthine + Ribose 1-phosphate LEFT_TO_RIGHT C10H12N4O5 Inosine 268.08078 58484 ChemSpider 1038 PubChem-compound C00212 KEGG Compound 1.0 GO:0005829 GENE ONTOLOGY 7540-64-9 CAS 1.0 Adenosine HMDB59597 HMDB HYPOXANTHINE BioCyc XANTHINE BioCyc 3.5.4.4 false 3.5.4.4 Adenosine + Hydrogen Ion + Water → Ammonium + Inosine LEFT_TO_RIGHT P0A6K6 UniProt 1.0 Xanthosine permease 1.0 O4P Phosphate 94.95342 1.0 SMILES CC1=C(C=CC(=C1)C1=CC(C)=C(C=C1)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O 1010 ChemSpider Phosphopentomutase Adenine HMDB41827 HMDB 439167 PubChem-compound C5H5N5 Adenine 135.05449 1.0 64959 PubChem-compound 1.0 C00119 KEGG Compound C00117 KEGG Compound Ammonium 388313 ChemSpider Hydrogen Ion HMDB01548 HMDB Xanthine phosphoribosyltransferase SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1NC=NC2=O Cytosol SubPathwayInteraction3148 SubPathway3148Reaction SubPathwayReaction 218 ChemSpider 1.0 Reaction5899 false Ribose 1-phosphate → D-Ribose 5-phosphate LEFT_TO_RIGHT C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 SMILES [O-]P([O-])([O-])=O GUANOSINE BioCyc 2.4.2.1 false 2.4.2.1 Phosphate + Xanthosine → Ribose 1-phosphate + Xanthine LEFT_TO_RIGHT Reaction6066 false Adenosine + Phosphate → Adenine + Ribose 1-phosphate LEFT_TO_RIGHT C5H4N4O2 Xanthine 152.03343 http://identifiers.org/smpdb/SMP02088 SMPDB C00009 KEGG Compound CHEBI:15652 ChEBI HMDB01554 HMDB ADENINE BioCyc CHEBI:17712 ChEBI Hydrogen Ion 1151 ChemSpider C00001 KEGG Compound 790 PubChem-compound C00242 KEGG Compound Adenosine C34H28N6O14S4 diphosphate 872.0546 CHEBI:18367 ChEBI 1032 ChemSpider Guanine 73323 PubChem-compound 66054 ChemSpider P22333 UniProt SMILES NC1=C2NC=NC2=NC=N1 Guanosine HMDB01429 HMDB Purine nucleoside phosphorylase deoD-type 1.0 Reaction6058 false Guanosine + Phosphate → Guanine + Ribose 1-phosphate LEFT_TO_RIGHT C10H13N5O5 Guanosine 283.09167 Xanthosine phosphorylase C5H5N5O Guanine 151.04941 60961 PubChem-compound CHEBI:17368 ChEBI 1.0 GUANINE BioCyc 118-00-3 CAS C01342 KEGG Compound 6802 PubChem-compound CHEBI:28938 ChEBI 7339 PubChem-compound purine nucleoside phosphorylase P45563 UniProt 6.0 P45562 UniProt http://identifiers.org/smpdb/SMP00927 SMPDB P0AFF4 UniProt 1.0 Xanthine C5H11O8P Ribose 1-phosphate 230.01915 Reaction6088 false Phosphoribosyl pyrophosphate + Xanthine → Xanthylic acid + diphosphate LEFT_TO_RIGHT GO:0005620 GENE ONTOLOGY Xanthosine CHEBI:16708 ChEBI P0A9M5 UniProt Phosphoribosyl pyrophosphate CHEBI:18107 ChEBI H Hydrogen Ion 1.007825 68-94-0 CAS Xanthosine P0ABP8 UniProt 1.0 C00385 KEGG Compound xanthosine phosphorylase C00262 KEGG Compound C00147 KEGG Compound Adenosine deaminase C00387 KEGG Compound Nucleoside permease nupG Transport507 false Adenosine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT xanthine-guanine phosphoribosyltransferase Transport508 false Xanthosine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 73-24-5 CAS 764 PubChem-compound purine nucleotides de novo biosynthesis SubPathway ReactionCatalysis6050 ACTIVATION CPD-8587 BioCyc 146-80-5 CAS Water CHEBI:52742 ChEBI 1.0 SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H]1O CHEBI:16300 ChEBI 5799 ChemSpider Xanthosine 1.0 PW002076 PathWhiz 768 ChemSpider Xanthosine phosphorylase 7062 ChemSpider 73-40-5 CAS C00294 KEGG Compound Purine nucleoside phosphorylase deoD-type 14798-03-9 CAS 14075-00-4 CAS 6.0 HMDB00195 HMDB 7732-18-5 CAS CHEBI:16750 ChEBI 1.0 diphosphate INOSINE BioCyc SMILES NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1 SMILES [NH4+] purine ribonucleosides degradation 1.0 6544 ChemSpider XANTHOSINE-5-PHOSPHATE BioCyc 58-61-7 CAS C00620 KEGG Compound C10H13N4O9P Xanthylic acid 364.04202 Xanthylic acid D-Ribose 5-phosphate C5H11O8P D-Ribose 5-phosphate 230.01915 962 PubChem-compound HMDB00299 HMDB CHEBI:16335 ChEBI Adenosine deaminase HMDB00292 HMDB HMDB00050 HMDB Phosphate 1.0 Nucleoside permease nupG HMDB02111 HMDB C00080 KEGG Compound 4.0 439236 PubChem-compound Periplasmic Space TransportCatalysis439 ACTIVATION TransportCatalysis438 ACTIVATION ReactionCatalysis6014 ACTIVATION ReactionCatalysis6013 ACTIVATION ADENOSINE BioCyc CHEBI:15377 ChEBI 14265-44-2 CAS CHEBI:15378 ChEBI SMILES [H+] ReactionCatalysis6022 ACTIVATION Inosine 1.0 1.0 SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1NC(=O)NC2=O RIBOSE-5P BioCyc SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O ReactionCatalysis6028 ACTIVATION ReactionCatalysis6027 ACTIVATION HMDB00034 HMDB HMDB01489 HMDB HMDB00157 HMDB C00655 KEGG Compound C10H12N4O6 Xanthosine 284.07568 16741146 PubChem-compound 388373 ChemSpider 69-89-6 CAS PRPP BioCyc Xanthosine permease SMILES O=C1NC2=C(NC=N2)C(=O)N1 58-63-9 CAS H2O Water 18.010565 190 PubChem-compound 54923 ChemSpider SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O Adenosine PW000910 PathWhiz 1.0 ReactionCatalysis5862 ACTIVATION 1061 PubChem-compound 523-98-8 CAS Hydrogen Ion HMDB00280 HMDB Xanthine phosphoribosyltransferase Hypoxanthine 1188 PubChem-compound 744 ChemSpider SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N1 SMILES NC1=NC(=O)C2=C(N1)N=CN2 Phosphopentomutase 1.0 185 ChemSpider C5H4N4O Hypoxanthine 136.03851 4300-28-1 CAS nupG nupG xapB xapA deoD deoD add deoD deoB gpt Adenosine Adenosine Hydrogen Ion Hydrogen Ion Adenosine Adenosine Hydrogen Ion Hydrogen Ion Xanthosine Xanthosine Hydrogen Ion Hydrogen Ion Xanthosine Phosphate Xanthine Ribose 1-phosphate Adenosine Phosphate Adenine Inosine Phosphate Hypoxanthine Adenosine Water Hydrogen Ion Ammonium Guanosine Phosphate Guanine D-Ribose 5-phosphate Phosphoribosyl pyrophosphate Xanthylic acid diphosphate purine nucleotides de novo biosynthesis