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Pathway Description
NAD Phosphorylation and Dephosphorylation
Escherichia coli
Metabolic Pathway
NAD kinase is required for converting NAD to NADP in various organisms such as groups of archaea, eubacteria and eukaryotes. For example, NAD kinase has shown its important role for the growth in Salmonella enterica and the importance in E.coli. NADP can be converted back to NAD via facilitation of alkaline phosphatase with water (hydroxylation).
References
NAD Phosphorylation and Dephosphorylation References
Lundquist R, Olivera BM: Pyridine nucleotide metabolism in Escherichia coli. I. Exponential growth. J Biol Chem. 1971 Feb 25;246(4):1107-16.
Pubmed: 5543676
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