Loading Pathway...
CHEBI:16895 ChEBI C00315 KEGG Compound PUTRESCINE BioCyc 23656-67-9 CAS 1.0 PW002085 PathWhiz Spermidine synthase 937 ChemSpider Spermidine HMDB01185 HMDB 5-Methylthioribose 1.0 Water 1.0 Spermidine synthase SMILES NCCCCNCCCN adenosylmethionine decarboxylase 13837702 ChemSpider 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase SMILES O 5-Methylthioribose 1.0 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Transport511 false 5-Methylthioribose (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT 2.0 P0AF12 UniProt SMILES CSC[C@H]1O[C@@H](O)[C@H](O)[C@@H]1O 1071 ChemSpider C01137 KEGG Compound S-ADENOSYLMETHIONINAMINE BioCyc S-adenosylmethionine decarboxylase proenzyme 124-20-9 CAS Putrescine 4.1.1.50 false 4.1.1.50 Hydrogen Ion + S-Adenosylmethionine → Carbon dioxide + S-Adenosylmethioninamine LEFT_TO_RIGHT 388529 ChemSpider 2.5.1.- false 2.5.1.- Putrescine + S-Adenosylmethioninamine → 5'-S-methyl-5'-thioadenosine + Hydrogen Ion + Spermidine LEFT_TO_RIGHT C4H12N2 Putrescine 88.10005 3.2.2.9 false 3.2.2.9 5'-S-methyl-5'-thioadenosine + Water → 5-Methylthioribose + Adenine LEFT_TO_RIGHT ReactionCatalysis5138 ACTIVATION ReactionCatalysis5136 ACTIVATION ReactionCatalysis5137 ACTIVATION 5'-S-methyl-5'-thioadenosine C15H23N6O5S S-Adenosylmethionine 399.14505 1.0 1038 PubChem-compound 7732-18-5 CAS Spermidine biosynthesis and metabolism GO:0005829 GENE ONTOLOGY 1.0 HMDB59597 HMDB 274 ChemSpider HMDB00988 HMDB 1.0 P0A7F6 UniProt CHEBI:16526 ChEBI SMILES CSCC1OC(C(O)C1O)N1C=NC2=C(N)N=CN=C12 1010 ChemSpider 5-Methylthioribose S-Adenosylmethioninamine Adenine SMILES NCCCCN HMDB01967 HMDB C14H23N6O3S S-Adenosylmethioninamine 355.15524 C5H5N5 Adenine 135.05449 962 PubChem-compound 31983 ChemSpider 8.0 CHEBI:17148 ChEBI CHEBI:16610 ChEBI Hydrogen Ion SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 Cytosol CO2 Carbon dioxide 43.98983 1.0 HMDB02111 HMDB C00080 KEGG Compound S-adenosylmethionine decarboxylase proenzyme Periplasmic Space 124-38-9 CAS 1.0 CHEBI:15377 ChEBI 110-60-1 CAS CHEBI:15378 ChEBI SMILES [H+] CHEBI:15414 ChEBI Spermidine synthase C11H15N5O3S 5'-S-methyl-5'-thioadenosine 297.08957 ADENINE BioCyc C00001 KEGG Compound S-Adenosylmethionine 1045 PubChem-compound SMP02097 SMPDB 1.0 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 280 PubChem-compound SMILES C[S+](CCCN)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N SMILES NC1=C2NC=NC2=NC=N1 439904 PubChem-compound HMDB00034 HMDB C00019 KEGG Compound CHEBI:15625 ChEBI S-ADENOSYLMETHIONINE BioCyc C00011 KEGG Compound SMILES O=C=O HMDB01087 HMDB C03089 KEGG Compound C00134 KEGG Compound H2O Water 18.010565 190 PubChem-compound C7H19N3 Spermidine 145.1579 388938 ChemSpider GO:0005620 GENE ONTOLOGY 439415 PubChem-compound CHEBI:16708 ChEBI 29908-03-0 CAS H Hydrogen Ion 1.007825 22365-13-5 CAS HMDB01257 HMDB C6H12O4S 5-Methylthioribose 180.04562 HMDB01414 HMDB P09158 UniProt SPERMIDINE BioCyc Carbon dioxide 1102 PubChem-compound CPD-560 BioCyc C00147 KEGG Compound 2.0 24762165 PubChem-compound 1.0 185 ChemSpider 1.0 73-24-5 CAS S- adenosylmethionine decarboxylase proenzyme Spermidine synthase 5'- methylthioadenosine/S- adenosylhomocysteine nucleosidase 5- Methylthioribose 5- Methylthioribose S- Adenosylmethionine H + CO 2 S- Adenosylmethioninamine Putrescine Spermidine H + 5'-S-methyl- 5'- thioadenosine H 2 O Adenine Pyruvic acid Magnesium
CHEBI:16895 ChEBI C00315 KEGG Compound PUTRESCINE BioCyc 23656-67-9 CAS 1.0 PW002085 PathWhiz Spermidine synthase 937 ChemSpider Spermidine HMDB01185 HMDB 5-Methylthioribose 1.0 Water 1.0 Spermidine synthase SMILES NCCCCNCCCN adenosylmethionine decarboxylase 13837702 ChemSpider 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase SMILES O 5-Methylthioribose 1.0 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Transport511 false 5-Methylthioribose (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT 2.0 P0AF12 UniProt SMILES CSC[C@H]1O[C@@H](O)[C@H](O)[C@@H]1O 1071 ChemSpider C01137 KEGG Compound S-ADENOSYLMETHIONINAMINE BioCyc S-adenosylmethionine decarboxylase proenzyme 124-20-9 CAS Putrescine 4.1.1.50 false 4.1.1.50 Hydrogen Ion + S-Adenosylmethionine → Carbon dioxide + S-Adenosylmethioninamine LEFT_TO_RIGHT 388529 ChemSpider 2.5.1.- false 2.5.1.- Putrescine + S-Adenosylmethioninamine → 5'-S-methyl-5'-thioadenosine + Hydrogen Ion + Spermidine LEFT_TO_RIGHT C4H12N2 Putrescine 88.10005 3.2.2.9 false 3.2.2.9 5'-S-methyl-5'-thioadenosine + Water → 5-Methylthioribose + Adenine LEFT_TO_RIGHT ReactionCatalysis5138 ACTIVATION ReactionCatalysis5136 ACTIVATION ReactionCatalysis5137 ACTIVATION 5'-S-methyl-5'-thioadenosine C15H23N6O5S S-Adenosylmethionine 399.14505 1.0 1038 PubChem-compound 7732-18-5 CAS Spermidine biosynthesis and metabolism GO:0005829 GENE ONTOLOGY 1.0 HMDB59597 HMDB 274 ChemSpider HMDB00988 HMDB 1.0 P0A7F6 UniProt CHEBI:16526 ChEBI SMILES CSCC1OC(C(O)C1O)N1C=NC2=C(N)N=CN=C12 1010 ChemSpider 5-Methylthioribose S-Adenosylmethioninamine Adenine SMILES NCCCCN HMDB01967 HMDB C14H23N6O3S S-Adenosylmethioninamine 355.15524 C5H5N5 Adenine 135.05449 962 PubChem-compound 31983 ChemSpider 8.0 CHEBI:17148 ChEBI CHEBI:16610 ChEBI Hydrogen Ion SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 Cytosol CO2 Carbon dioxide 43.98983 1.0 HMDB02111 HMDB C00080 KEGG Compound S-adenosylmethionine decarboxylase proenzyme Periplasmic Space 124-38-9 CAS 1.0 CHEBI:15377 ChEBI 110-60-1 CAS CHEBI:15378 ChEBI SMILES [H+] CHEBI:15414 ChEBI Spermidine synthase C11H15N5O3S 5'-S-methyl-5'-thioadenosine 297.08957 ADENINE BioCyc C00001 KEGG Compound S-Adenosylmethionine 1045 PubChem-compound http://identifiers.org/smpdb/SMP02097 SMPDB 1.0 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 280 PubChem-compound SMILES C[S+](CCCN)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N SMILES NC1=C2NC=NC2=NC=N1 439904 PubChem-compound HMDB00034 HMDB C00019 KEGG Compound CHEBI:15625 ChEBI S-ADENOSYLMETHIONINE BioCyc C00011 KEGG Compound SMILES O=C=O HMDB01087 HMDB C03089 KEGG Compound C00134 KEGG Compound H2O Water 18.010565 190 PubChem-compound C7H19N3 Spermidine 145.1579 388938 ChemSpider GO:0005620 GENE ONTOLOGY 439415 PubChem-compound CHEBI:16708 ChEBI 29908-03-0 CAS H Hydrogen Ion 1.007825 22365-13-5 CAS HMDB01257 HMDB C6H12O4S 5-Methylthioribose 180.04562 HMDB01414 HMDB P09158 UniProt SPERMIDINE BioCyc Carbon dioxide 1102 PubChem-compound CPD-560 BioCyc C00147 KEGG Compound 2.0 24762165 PubChem-compound 1.0 185 ChemSpider 1.0 73-24-5 CAS speD speE mtn 5- Methylthioribose 5- Methylthioribose S- Adenosylmethionine Hydrogen Ion Carbon dioxide S- Adenosylmethioninamine Putrescine Spermidine Hydrogen Ion 5'-S-methyl- 5'- thioadenosine Water Adenine