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UDP-α-D-galactose CHEBI:16015 ChEBI 30572 ChemSpider 17215925 ChemSpider 2.0 Reaction6030 false D-glucosamine 6-phosphate ↔ Glucosamine-1P REVERSIBLE C23H38N7O17P3S Acetyl-CoA 809.1258 Reaction6031 false Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate + Uridine triphosphate → Uridine diphosphate-N-acetylglucosamine + diphosphate LEFT_TO_RIGHT 937 ChemSpider 3315 PubChem-compound HMDB01342 HMDB NADH dTDP-D-glucose 439153 PubChem-compound SMILES O C15H24N2O17P2 UDP-D-Galacto-1,4-furanose 566.055 Glucose-6-phosphate isomerase Reaction6147 false Hydrogen Ion + NADH + dTDP-4-dehydro-beta-L-rhamnose → NADP + TDP-Rhamnose LEFT_TO_RIGHT 1.0 2.7.7.23 false 2.7.7.23 Acetyl-CoA + Glucosamine-1P → Coenzyme A + Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate LEFT_TO_RIGHT 6133 PubChem-compound SMILES C[C@@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@H](O)[C@H]1O P37747 UniProt SMILES C[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H](O)C1=O P37745 UniProt HMDB00148 HMDB 4.0 P37744 UniProt 5961 PubChem-compound CHEBI:16264 ChEBI Bifunctional protein glmU D-fructose-6-phosphate aminotransferase 1.0 528-04-1 CAS P0ACC7 UniProt 6816 PubChem-compound HMDB01109 HMDB 1.0 ReactionCatalysis6105 ACTIVATION 1.0 C00459 KEGG Compound 388455 ChemSpider 53-59-8 CAS SMP00841 SMPDB HMDB01328 HMDB 5746 ChemSpider HMDB01206 HMDB 1.0 365-08-2 CAS UDP-galactopyranose mutase 1038 PubChem-compound dTDP-4-dehydrorhamnose 3,5-epimerase C04256 KEGG Compound CHEBI:16474 ChEBI dTDP-4-dehydrorhamnose reductase HMDB59597 HMDB fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase 64968 PubChem-compound SMP02101 SMPDB 393240 ChemSpider 8140645 ChemSpider CHEBI:16908 ChEBI C15H22N2O17P2 UDP-α-D-galactose 564.04047 PW000831 PathWhiz CHEBI:15713 ChEBI Acetyl-CoA 58493 ChemSpider SMILES CC1=C(C=CC(=C1)C1=CC(C)=C(C=C1)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O NADPH 1010 ChemSpider CHEBI:58247 ChEBI SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] NADP GLUCOSAMINE-1P BioCyc 440272 PubChem-compound C21H30N7O17P3 NADPH 745.0911 1.0 P55293 UniProt C21H29N7O17P3 NADP 744.08325 SMP00851 SMPDB PW000821 PathWhiz P37760 UniProt 1.0 2.0 C6H14NO8P Glucosamine-1P 259.04572 NADPH BioCyc HMDB01423 HMDB Amino sugar and nucleotide sugar metabolism III SubPathway 1.0 SMP00903 SMPDB galactose degradation/Leloir Pathway SubPathway galactose metabolism SubPathway Hydrogen Ion C5H10N2O3 L-Glutamine 146.06914 HMDB00217 HMDB lipopolysaccharide biosynthesis SubPathway dTDP-glucose 4,6-dehydratase 58-68-4 CAS SubPathwayInteraction3153 SubPathwayReaction SubPathway3153Reaction Glucose-6-phosphate isomerase C9H15N2O15P3 Uridine triphosphate 483.96854 L-Glutamic acid SubPathwayInteraction3151 SubPathway3151Reaction SubPathwayReaction SubPathwayInteraction3152 SubPathway3152Reaction SubPathwayReaction SubPathwayInteraction3150 SubPathwayReaction SubPathway3150Reaction 1.0 C17H27N3O17P2 Uridine diphosphate-N-acetylglucosamine 607.08154 HMDB00221 HMDB 1.0 C00006 KEGG Compound β-D-fructofuranose 6-phosphate SMP00914 SMPDB 1.0 CHEBI:18009 ChEBI PW000895 PathWhiz C00001 KEGG Compound C34H28N6O14S4 diphosphate 872.0546 α-D-glucose 1-phosphate CHEBI:35248 ChEBI C00005 KEGG Compound β-D-glucose 6-phosphate C00004 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O N-Acetyl-glucosamine 1-phosphate 5.4.99.9 false 5.4.99.9 UDP-α-D-galactose ↔ UDP-D-Galacto-1,4-furanose REVERSIBLE C8H16NO9P N-Acetyl-glucosamine 1-phosphate 301.05627 1.0 Phosphoglucosamine mutase SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 1.0 GLN BioCyc GLT BioCyc ReactionCatalysis3277 ACTIVATION 53-57-6 CAS 2.7.7.24 false 2.7.7.24 Hydrogen Ion + Thymidine 5'-triphosphate + α-D-glucose 1-phosphate → dTDP-D-glucose + diphosphate LEFT_TO_RIGHT C6H11O9P β-D-fructofuranose 6-phosphate 258.01517 PW000884 PathWhiz β-D-glucose 6-phosphate C00010 KEGG Compound α-D-glucose 1-phosphate CHEBI:7125 ChEBI Uridine diphosphate-N-acetylglucosamine NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 C16H26N2O16P2 dTDP-D-glucose 564.07574 1.0 UDP-D-Galacto-1,4-furanose Uridine triphosphate SMILES [H][C@]1(O)C[C@]([H])(O[C@@]1([H])CCP([O-])(=O)OP([O-])(=O)O[C@@]1([H])O[C@@]([H])(C)[C@@]([H])(O)[C@@]([H])(O)[C@@]1([H])O)[N+]1=C[C+](C)C(O)=NC1=O H Hydrogen Ion 1.007825 1.0 dTDP-4-dehydro-beta-L-rhamnose 25244316 PubChem-compound L-Glutamine Glucosamine-1P dTDP-glucose 4,6-dehydratase C00025 KEGG Compound dTDP-glucose pyrophosphorylase C00024 KEGG Compound CHEBI:58439 ChEBI Thymidine 5'-triphosphate C10H17N2O14P3 Thymidine 5'-triphosphate 481.98926 phosphoglucose isomerase D-glucosamine 6-phosphate C6H14NO8P D-glucosamine 6-phosphate 259.04572 1.0 C16H24N2O15P2 dTDP-4-dehydro-beta-L-rhamnose 546.0652 TTP BioCyc dTDP-6-deoxy-L-mannose PW002089 PathWhiz N-ACETYL-D-GLUCOSAMINE-1-P BioCyc dTDP-4-dehydro-6-deoxy-D-glucose SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Water SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O2)C(=O)NC1=O ReactionCatalysis6058 ACTIVATION C17H26N2O14P2 TDP-Rhamnose 544.08594 ReactionCatalysis6056 ACTIVATION SMILES OC[C@H]1OC(OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O ReactionCatalysis6061 ACTIVATION C00842 KEGG Compound ReactionCatalysis6064 ACTIVATION CO-A BioCyc ReactionCatalysis6063 ACTIVATION C00043 KEGG Compound 5675 ChemSpider 72-89-9 CAS 56-85-9 CAS Coenzyme A 1.0 C21H36N7O16P3S Coenzyme A 767.11523 SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O Reaction6098 false dTDP-D-glucose → Water + dTDP-4-dehydro-6-deoxy-D-glucose LEFT_TO_RIGHT P31120 UniProt dTDP-glucose pyrophosphorylase UTP BioCyc O-antigen building blocks biosynthesis 5903 ChemSpider 6557 ChemSpider 1.0 Phosphoglucosamine mutase CHEBI:18251 ChEBI SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS 388299 ChemSpider diphosphate 56-86-0 CAS 1.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound HMDB00641 HMDB C16H24N2O15P2 dTDP-4-dehydro-6-deoxy-D-glucose 546.0652 3.0 1.0 C16H26N2O15P2 dTDP-6-deoxy-L-mannose 548.0809 445675 PubChem-compound UDP-N-ACETYL-D-GLUCOSAMINE BioCyc C00064 KEGG Compound 1.0 6866-69-9 CAS DTDP-D-GLUCOSE BioCyc P0A6T1 UniProt 439324 PubChem-compound 1.0 962 PubChem-compound 389248 ChemSpider SMILES OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O 392413 ChemSpider HMDB00290 HMDB CHEBI:18077 ChEBI C00075 KEGG Compound HMDB02111 HMDB Bifunctional protein glmU C00080 KEGG Compound ReactionCatalysis5966 ACTIVATION 9965052 PubChem-compound Reaction6100 false Hydrogen Ion + NADPH + dTDP-4-dehydro-beta-L-rhamnose → NADP + dTDP-6-deoxy-L-mannose LEFT_TO_RIGHT Reaction6102 false β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate REVERSIBLE SMILES N[C@@H](CCC(O)=O)C(O)=O 1.0 Reaction6103 false L-Glutamine + β-D-fructofuranose 6-phosphate ↔ D-glucosamine 6-phosphate + L-Glutamic acid REVERSIBLE CHEBI:15377 ChEBI CHEBI:45868 ChEBI 1.0 CHEBI:15378 ChEBI SMILES [H+] 5886 PubChem-compound 1.0 dTDP-4-dehydrorhamnose 3,5-epimerase UDP-galactopyranose mutase 2196-62-5 CAS SMILES C[C@@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@H](O)C1=O SMILES N[C@H]1C(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O ReactionCatalysis5851 ACTIVATION HMDB01487 HMDB dTDP-glucose pyrophosphorylase 1.0 HMDB01367 HMDB 444493 PubChem-compound dTDP-glucose 4,6-dehydratase SMILES N[C@@H](CCC(N)=O)C(O)=O SMILES N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OP(O)(O)=O 2.0 22833512 PubChem-compound SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O ACETYL-COA BioCyc CHEBI:18050 ChEBI H2O Water 18.010565 P17169 UniProt TDP-Rhamnose 5.1.3.13 false 5.1.3.13 dTDP-4-dehydro-6-deoxy-D-glucose → dTDP-4-dehydro-beta-L-rhamnose LEFT_TO_RIGHT NADH BioCyc SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O SMILES [H][C@@](O)(CO)[C@]1([H])O[C@]([H])(OP(O)(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=CC(O)=NC3=O)[C@]([H])(O)[C@]2([H])O)[C@]([H])(O)[C@@]1([H])O dTDP-4-dehydrorhamnose reductase 63-39-8 CAS CHEBI:15351 ChEBI CHEBI:58601 ChEBI CHEBI:57634 ChEBI HMDB00285 HMDB SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1OP(O)(O)=O 85-61-0 CAS Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] ReactionCatalysis5996 ACTIVATION ReactionCatalysis5995 ACTIVATION UDP- galactopyranose mutase dTDP-glucose pyrophosphorylase dTDP-glucose 4,6-dehydratase dTDP-4- dehydrorhamnose 3,5-epimerase dTDP-4- dehydrorhamnose reductase Glucose-6- phosphate isomerase Glucosamine-- fructose-6- phosphate aminotransferase [isomerizing] Phosphoglucosamine mutase Bifunctional protein glmU Bifunctional protein glmU dTDP-4- dehydrorhamnose reductase UDP-α-D- galactose UDP-D- Galacto-1,4- furanose α-D-glucose 1-phosphate Thymidine 5'-triphosphate H + dTDP-D-glucose diphosphate dTDP-4- dehydro-6- deoxy-D- glucose H 2 O dTDP-4- dehydro-beta- L-rhamnose NADPH H + dTDP-6-deoxy- L-mannose NADP β-D-glucose 6-phosphate β-D- fructofuranose 6-phosphate L-Glutamine D-glucosamine 6-phosphate L-Glutamic acid Glucosamine-1P Acetyl-CoA N-Acetyl- glucosamine 1-phosphate CoA H + Uridine triphosphate H + Uridine diphosphate- N- acetylglucosamine diphosphate NADH H + NADP TDP-Rhamnose NAD lipopolysaccharide biosynthesis galactose degradation/Leloir Pathway galactose metabolism Amino sugar and nucleotide sugar metabolism III
UDP-α-D-galactose CHEBI:16015 ChEBI 30572 ChemSpider 17215925 ChemSpider 2.0 Reaction6030 false D-glucosamine 6-phosphate ↔ Glucosamine-1P REVERSIBLE C23H38N7O17P3S Acetyl-CoA 809.1258 Reaction6031 false Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate + Uridine triphosphate → Uridine diphosphate-N-acetylglucosamine + diphosphate LEFT_TO_RIGHT 937 ChemSpider 3315 PubChem-compound HMDB01342 HMDB NADH dTDP-D-glucose 439153 PubChem-compound SMILES O C15H24N2O17P2 UDP-D-Galacto-1,4-furanose 566.055 Glucose-6-phosphate isomerase Reaction6147 false Hydrogen Ion + NADH + dTDP-4-dehydro-beta-L-rhamnose → NADP + TDP-Rhamnose LEFT_TO_RIGHT 1.0 2.7.7.23 false 2.7.7.23 Acetyl-CoA + Glucosamine-1P → Coenzyme A + Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate LEFT_TO_RIGHT 6133 PubChem-compound SMILES C[C@@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@H](O)[C@H]1O P37747 UniProt SMILES C[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H](O)C1=O P37745 UniProt HMDB00148 HMDB 4.0 P37744 UniProt 5961 PubChem-compound CHEBI:16264 ChEBI Bifunctional protein glmU D-fructose-6-phosphate aminotransferase 1.0 528-04-1 CAS P0ACC7 UniProt 6816 PubChem-compound HMDB01109 HMDB 1.0 galactose degradation/Leloir Pathway SubPathway ReactionCatalysis6105 ACTIVATION 1.0 C00459 KEGG Compound 388455 ChemSpider 53-59-8 CAS http://identifiers.org/smpdb/SMP00841 SMPDB HMDB01328 HMDB 5746 ChemSpider HMDB01206 HMDB 1.0 365-08-2 CAS UDP-galactopyranose mutase 1038 PubChem-compound dTDP-4-dehydrorhamnose 3,5-epimerase C04256 KEGG Compound CHEBI:16474 ChEBI dTDP-4-dehydrorhamnose reductase HMDB59597 HMDB fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase 64968 PubChem-compound Amino sugar and nucleotide sugar metabolism III SubPathway http://identifiers.org/smpdb/SMP02101 SMPDB 393240 ChemSpider 8140645 ChemSpider CHEBI:16908 ChEBI C15H22N2O17P2 UDP-α-D-galactose 564.04047 PW000831 PathWhiz CHEBI:15713 ChEBI Acetyl-CoA 58493 ChemSpider SMILES CC1=C(C=CC(=C1)C1=CC(C)=C(C=C1)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O)N=NC1=C(O)C2=C(C=C1)C(=CC(=C2N)S(O)(=O)=O)S(O)(=O)=O NADPH 1010 ChemSpider CHEBI:58247 ChEBI SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] NADP GLUCOSAMINE-1P BioCyc 440272 PubChem-compound C21H30N7O17P3 NADPH 745.0911 1.0 P55293 UniProt C21H29N7O17P3 NADP 744.08325 http://identifiers.org/smpdb/SMP00851 SMPDB PW000821 PathWhiz P37760 UniProt 1.0 2.0 C6H14NO8P Glucosamine-1P 259.04572 NADPH BioCyc HMDB01423 HMDB 1.0 http://identifiers.org/smpdb/SMP00903 SMPDB Hydrogen Ion C5H10N2O3 L-Glutamine 146.06914 HMDB00217 HMDB dTDP-glucose 4,6-dehydratase 58-68-4 CAS SubPathwayInteraction3153 SubPathwayReaction SubPathway3153Reaction Glucose-6-phosphate isomerase C9H15N2O15P3 Uridine triphosphate 483.96854 L-Glutamic acid SubPathwayInteraction3151 SubPathway3151Reaction SubPathwayReaction SubPathwayInteraction3152 SubPathway3152Reaction SubPathwayReaction SubPathwayInteraction3150 SubPathwayReaction SubPathway3150Reaction 1.0 C17H27N3O17P2 Uridine diphosphate-N-acetylglucosamine 607.08154 lipopolysaccharide biosynthesis SubPathway HMDB00221 HMDB 1.0 C00006 KEGG Compound β-D-fructofuranose 6-phosphate http://identifiers.org/smpdb/SMP00914 SMPDB 1.0 CHEBI:18009 ChEBI PW000895 PathWhiz C00001 KEGG Compound C34H28N6O14S4 diphosphate 872.0546 α-D-glucose 1-phosphate CHEBI:35248 ChEBI C00005 KEGG Compound β-D-glucose 6-phosphate C00004 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O N-Acetyl-glucosamine 1-phosphate 5.4.99.9 false 5.4.99.9 UDP-α-D-galactose ↔ UDP-D-Galacto-1,4-furanose REVERSIBLE C8H16NO9P N-Acetyl-glucosamine 1-phosphate 301.05627 1.0 Phosphoglucosamine mutase SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 1.0 GLN BioCyc GLT BioCyc ReactionCatalysis3277 ACTIVATION 53-57-6 CAS 2.7.7.24 false 2.7.7.24 Hydrogen Ion + Thymidine 5'-triphosphate + α-D-glucose 1-phosphate → dTDP-D-glucose + diphosphate LEFT_TO_RIGHT C6H11O9P β-D-fructofuranose 6-phosphate 258.01517 PW000884 PathWhiz β-D-glucose 6-phosphate C00010 KEGG Compound α-D-glucose 1-phosphate CHEBI:7125 ChEBI Uridine diphosphate-N-acetylglucosamine NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 C16H26N2O16P2 dTDP-D-glucose 564.07574 1.0 UDP-D-Galacto-1,4-furanose Uridine triphosphate SMILES [H][C@]1(O)C[C@]([H])(O[C@@]1([H])CCP([O-])(=O)OP([O-])(=O)O[C@@]1([H])O[C@@]([H])(C)[C@@]([H])(O)[C@@]([H])(O)[C@@]1([H])O)[N+]1=C[C+](C)C(O)=NC1=O H Hydrogen Ion 1.007825 1.0 dTDP-4-dehydro-beta-L-rhamnose 25244316 PubChem-compound L-Glutamine Glucosamine-1P dTDP-glucose 4,6-dehydratase C00025 KEGG Compound dTDP-glucose pyrophosphorylase C00024 KEGG Compound CHEBI:58439 ChEBI Thymidine 5'-triphosphate C10H17N2O14P3 Thymidine 5'-triphosphate 481.98926 phosphoglucose isomerase D-glucosamine 6-phosphate C6H14NO8P D-glucosamine 6-phosphate 259.04572 1.0 C16H24N2O15P2 dTDP-4-dehydro-beta-L-rhamnose 546.0652 TTP BioCyc dTDP-6-deoxy-L-mannose PW002089 PathWhiz N-ACETYL-D-GLUCOSAMINE-1-P BioCyc dTDP-4-dehydro-6-deoxy-D-glucose SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Water SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O2)C(=O)NC1=O ReactionCatalysis6058 ACTIVATION C17H26N2O14P2 TDP-Rhamnose 544.08594 ReactionCatalysis6056 ACTIVATION SMILES OC[C@H]1OC(OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O ReactionCatalysis6061 ACTIVATION C00842 KEGG Compound ReactionCatalysis6064 ACTIVATION CO-A BioCyc ReactionCatalysis6063 ACTIVATION C00043 KEGG Compound 5675 ChemSpider 72-89-9 CAS 56-85-9 CAS Coenzyme A 1.0 C21H36N7O16P3S Coenzyme A 767.11523 SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O Reaction6098 false dTDP-D-glucose → Water + dTDP-4-dehydro-6-deoxy-D-glucose LEFT_TO_RIGHT P31120 UniProt dTDP-glucose pyrophosphorylase UTP BioCyc O-antigen building blocks biosynthesis 5903 ChemSpider 6557 ChemSpider 1.0 Phosphoglucosamine mutase CHEBI:18251 ChEBI SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS 388299 ChemSpider diphosphate 56-86-0 CAS 1.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound HMDB00641 HMDB C16H24N2O15P2 dTDP-4-dehydro-6-deoxy-D-glucose 546.0652 3.0 1.0 C16H26N2O15P2 dTDP-6-deoxy-L-mannose 548.0809 445675 PubChem-compound UDP-N-ACETYL-D-GLUCOSAMINE BioCyc C00064 KEGG Compound 1.0 6866-69-9 CAS DTDP-D-GLUCOSE BioCyc P0A6T1 UniProt 439324 PubChem-compound 1.0 galactose metabolism SubPathway 962 PubChem-compound 389248 ChemSpider SMILES OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O 392413 ChemSpider HMDB00290 HMDB CHEBI:18077 ChEBI C00075 KEGG Compound HMDB02111 HMDB Bifunctional protein glmU C00080 KEGG Compound ReactionCatalysis5966 ACTIVATION 9965052 PubChem-compound Reaction6100 false Hydrogen Ion + NADPH + dTDP-4-dehydro-beta-L-rhamnose → NADP + dTDP-6-deoxy-L-mannose LEFT_TO_RIGHT Reaction6102 false β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate REVERSIBLE SMILES N[C@@H](CCC(O)=O)C(O)=O 1.0 Reaction6103 false L-Glutamine + β-D-fructofuranose 6-phosphate ↔ D-glucosamine 6-phosphate + L-Glutamic acid REVERSIBLE CHEBI:15377 ChEBI CHEBI:45868 ChEBI 1.0 CHEBI:15378 ChEBI SMILES [H+] 5886 PubChem-compound 1.0 dTDP-4-dehydrorhamnose 3,5-epimerase UDP-galactopyranose mutase 2196-62-5 CAS SMILES C[C@@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@H](O)C1=O SMILES N[C@H]1C(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O ReactionCatalysis5851 ACTIVATION HMDB01487 HMDB dTDP-glucose pyrophosphorylase 1.0 HMDB01367 HMDB 444493 PubChem-compound dTDP-glucose 4,6-dehydratase SMILES N[C@@H](CCC(N)=O)C(O)=O SMILES N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OP(O)(O)=O 2.0 22833512 PubChem-compound SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O ACETYL-COA BioCyc CHEBI:18050 ChEBI H2O Water 18.010565 P17169 UniProt TDP-Rhamnose 5.1.3.13 false 5.1.3.13 dTDP-4-dehydro-6-deoxy-D-glucose → dTDP-4-dehydro-beta-L-rhamnose LEFT_TO_RIGHT NADH BioCyc SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O SMILES [H][C@@](O)(CO)[C@]1([H])O[C@]([H])(OP(O)(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])(N3C=CC(O)=NC3=O)[C@]([H])(O)[C@]2([H])O)[C@]([H])(O)[C@@]1([H])O dTDP-4-dehydrorhamnose reductase 63-39-8 CAS CHEBI:15351 ChEBI CHEBI:58601 ChEBI CHEBI:57634 ChEBI HMDB00285 HMDB SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1OP(O)(O)=O 85-61-0 CAS Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] ReactionCatalysis5996 ACTIVATION ReactionCatalysis5995 ACTIVATION