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Pathway Description
Xylose Degradation I
Escherichia coli
Metabolic Pathway
Escherichia coli can utilize D-xylose as the sole source of carbon and energy for the cell. A low-affinity proton motive force or a high-affinity ATP-driven (ABC) transport system brings unphosphorylated D-xylose into the cell. Following entry, D-xylose is converted to D-xylulose by an isomerase and then converted to the pentose phosphate pathway intermediate, D-xylulose 5-phosphate via a kinase. D-xylulose 5-phosphate can then enter pathways of metabolism to meet the cells needs.
References
Xylose Degradation I References
Batt CA, Jamieson AC, Vandeyar MA: Identification of essential histidine residues in the active site of Escherichia coli xylose (glucose) isomerase. Proc Natl Acad Sci U S A. 1990 Jan;87(2):618-22.
Pubmed: 2405386
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