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Mitochondria Pyrroline-5- carboxylate reductase Glutamate 5-kinase Aldehyde dehydrogenase 2, mitochondrial gamma-glutamyl phosphate reductase Aldehyde dehydrogenase 2, mitochondrial Unknown Unknown Unknown Unknown L-Proline L-Glutamic γ-semialdehyde H2O H+ 1-Pyrroline- 5-carboxylic acid H+ NADPH NADP Ubiquinone-1 H+ Ubiquinol-1 1-Pyrroline- 5-carboxylic acid L-Glutamic acid 5-phosphate H+ NADPH NADP Pi L-Glutamic acid ATP ADP γ-L-glutamyl 5-phosphate L-Glutamic γ-semialdehyde NAD H2O H+ NADH H2O H+ L-Glutamic acid ATP H2O ADP Pi H+
Mitochondria PRO3 PRO1 ALD2 PRO2 ALD2 Unknown Unknown Unknown Unknown L-Proline L-Glutamic γ-semialdehyde Water Hydrogen Ion 1-Pyrroline- 5-carboxylic acid Hydrogen Ion NADPH NADP Ubiquinone-1 Hydrogen Ion Ubiquinol-1 1-Pyrroline- 5-carboxylic acid L-Glutamic acid 5-phosphate Hydrogen Ion NADPH NADP Phosphate L-Glutamic acid Adenosine triphosphate Adenosine diphosphate γ-L-glutamyl 5-phosphate L-Glutamic γ-semialdehyde NAD Water Hydrogen Ion NADH Water Hydrogen Ion L-Glutamic acid Adenosine triphosphate Water Adenosine diphosphate Phosphate Hydrogen Ion
Mitochondria PRO3 PRO1 ALD2 PRO2 ALD2 Pro L-Gl-GA H2O H+ 1P5CA H+ NADPH NADP Coq1 H+ UBQ1 1P5CA L-G5P H+ NADPH NADP Pi Glu ATP ADP γLG5P L-Gl-GA NAD H2O H+