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Putative cystathionine beta-lyase N5- methyltetrahydropteroyltriglutamate- homocysteine methyltransferase S- adenosylmethionine synthetase S- AdenosylMethionine requiring S-adenosyl-L- homocysteine hydrolase aromatic amino acid aminotransferase II acireductone dioxygenase 2,3- dioxomethiopentane- 1-phosphate enolase/phosphatase Methylthioribulose- 1-phosphate DEhydratase MethylthioRibose- 1-phosphate Isomerase 5'- methylthioadenosine phosphorylase Aspartokinase aspartic beta semi-aldehyde dehydrogenase Homoserine dehydrogenase homoserine O-trans- acetylase Acetylhomoserine Hydrogen sulfide Acetic acid H + Homocysteine 5- Methyltetrahydropteroyltri- L-glutamate L-Methionine Tetrahydropteroyltri- L-glutamate ATP H 2 O P i PP i S- Adenosylmethionine H + S- Adenosylhomocysteine H 2 O Adenosine Homocysteine 2-Oxo-4- methylthiobutanoic acid L-Phenylalanine 2-Ketobutyric acid 1,2- Dihydroxy-3- keto-5- methylthiopentene O 2 H + Formic acid H 2 O 5- (Methylthio)- 2,3- dioxopentyl phosphate H + P i 5- Methylthioribulose 1-phosphate H 2 O 5- Methylthioribose 1-phosphate P i 5'-S-methyl- 5'- thioadenosine Adenine L-Aspartic acid ATP ADP L-Aspartyl-4- phosphate NADPH H + P i NADP L-Aspartate- semialdehyde NADPH H + L-Homoserine NADP Acetyl-CoA CoA Acetylhomoserine a demethylated methyl donor a methylated methyl donor
IRC7 MET6 SAM1 SAM2 SAH1 ARO9 ADI1 UTR4 MDE1 MRI1 MEU1 HOM3 HOM2 HOM6 MET2 Acetylhomoserine Hydrogen sulfide Acetic acid Hydrogen Ion Homocysteine 5- Methyltetrahydropteroyltri- L-glutamate L-Methionine Tetrahydropteroyltri- L-glutamate Adenosine triphosphate Water Phosphate Pyrophosphate S- Adenosylmethionine Hydrogen Ion S- Adenosylhomocysteine Water Adenosine Homocysteine 2-Oxo-4- methylthiobutanoic acid L-Phenylalanine 2-Ketobutyric acid 1,2- Dihydroxy-3- keto-5- methylthiopentene Oxygen Hydrogen Ion Formic acid Water 5- (Methylthio)- 2,3- dioxopentyl phosphate Hydrogen Ion Phosphate 5- Methylthioribulose 1-phosphate Water 5- Methylthioribose 1-phosphate Phosphate 5'-S-methyl- 5'- thioadenosine Adenine L-Aspartic acid Adenosine triphosphate Adenosine diphosphate L-Aspartyl-4- phosphate NADPH Hydrogen Ion Phosphate NADP L-Aspartate- semialdehyde NADPH Hydrogen Ion L-Homoserine NADP Acetyl-CoA Coenzyme A Acetylhomoserine a demethylated methyl donor a methylated methyl donor