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Aspartokinase aspartate semialdehyde dehydrogenase Aspartokinase Aspartokinase homoserine kinase Threonine synthase Threonine aldolase magnesium- activated aldehyde dehydrogenase, cytosolic potassium- activated aldehyde dehydrogenase, mitochondrial Acetaldehyde Acetaldehyde L-Aspartic acid ATP ADP L-Aspartyl-4- phosphate NADPH H + P i NADP L-Aspartate- semialdehyde H + NADPH NADP L-Homoserine ATP ADP H + O- Phosphohomoserine H 2 O P i L-Threonine Glycine NAD CoA NADH H + Acetyl-CoA CoA NAD NADH H + Acetyl-CoA
Mitochondria HOM3 Unknown HOM3 HOM3 Unknown THR4 GLY1 ALD6 ALD4 Acetaldehyde Acetaldehyde L-Aspartic acid Adenosine triphosphate Adenosine diphosphate L-Aspartyl-4- phosphate NADPH Hydrogen Ion Phosphate NADP L-Aspartate- semialdehyde Hydrogen Ion NADPH NADP L-Homoserine Adenosine triphosphate Adenosine diphosphate Hydrogen Ion O- Phosphohomoserine Water Phosphate L-Threonine Glycine NAD Coenzyme A NADH Hydrogen Ion Acetyl-CoA Coenzyme A NAD NADH Hydrogen Ion Acetyl-CoA