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dGTP amidophosphoribosyl transferase phosphoribosylamine- glycine ligase phosphoribosylglycinamide formyltransferase 2 phosphoribosylformylglycinamide synthetase phosphoribosylformylglycinamide cyclo-ligase N5- carboxyaminoimidazole ribonucleotide synthetase N5- carboxyaminoimidazole ribonucleotide mutase phosphoribosylaminoimidazole- succinocarboxamide synthase adenylosuccinate lyase AICAR transformylase / IMP cyclohydrolase Putative inosine-5'- monophosphate dehydrogenase 1 adenylosuccinate synthase adenylosuccinate lyase Adenylate kinase GMP synthetase Guanylate kinase nucleoside diphosphate kinase Unknown ribonucleoside diphosphate reductase 1 Unknown ribonucleoside- diphosphate reductase 2 ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase subunit beta, mitochondrial ribonucleoside- triphosphate reductase ribonucleoside diphosphate reductase 1 ribonucleoside diphosphate reductase 1 ribonucleoside- diphosphate reductase 2 ribonucleoside- diphosphate reductase 2 nucleoside diphosphate kinase AICAR transformylase / IMP cyclohydrolase cobinamide adenosyltransferase / cobalamin adenosyltransferase Succinyl-CoA ligase Succinyl-CoA ligase Phosphoribosyl pyrophosphate H 2 O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PP i Glycine ATP N1-(5- phospho-β-D- ribosyl)glycinamide P i ADP H + ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP P i H + H 2 O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid P i ADP H + ATP 5- Aminoimidazole ribonucleotide P i ADP H + HCO 3 - ATP N5- Carboxyaminoimidazole ribonucleotide ADP P i H + 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid ATP SAICAR P i ADP H + AICAR Fumaric acid FAICAR Inosinic acid H 2 O NAD H 2 O NADH H + Xanthylic acid L-Aspartic acid GTP GDP P i H + N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate ATP Adenosine diphosphate ATP L-Glutamine H 2 O AMP PP i L-Glutamic acid H + Guanosine monophosphate ATP ADP Guanosine diphosphate ATP ADP Guanosine triphosphate H 2 O H 2 O dGDP ATP ADP dGTP H 2 O dGDP P i H + H 2 O H + Adenosine triphosphate H 2 O dATP Adenosine diphosphate H 2 O dADP H 2 O dADP ATP ADP dATP 10- Formyltetrahydrofolate FAICAR tetrahydropteroyl mono-L- glutamate Cobalamin Triphosphate Adenosylcobalamin Itaconic acid CoA ADP P i Itaconyl-CoA Magnesium Magnesium Potassium Magnesium Magnesium Magnesium Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium 4Fe-4S Magnesium ATP synthase / thiamin triphosphate synthase a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein PRPP Biosynthesis Folate Biosynthesis ribonucleoside diphosphate reductase 1 ribonucleoside- diphosphate reductase 2 Zinc (II) ion