Canmetcon
Loading Pathway...
Endoplasmic Reticulum Hydroxymethylglutaryl- CoA synthase 3-ketoacyl-CoA thiolase, peroxisomal Mevalonate kinase Phosphomevalonate kinase Diphosphomevalonate decarboxylase Isopentenyl- diphosphate Delta-isomerase 1 Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Squalene synthase Squalene monooxygenase Lanosterol synthase Delta(24)- sterol reductase Lanosterol 14-alpha demethylase Delta(14)- sterol reductase 3-hydroxy-3- methylglutaryl- coenzyme A reductase Methylsterol monooxygenase Methylsterol monooxygenase Methylsterol monooxygenase C-3 sterol dehydrogenase 3-keto sterol reductase Methylsterol monooxygenase Methylsterol monooxygenase Methylsterol monooxygenase C-3 sterol dehydrogenase 3-keto sterol reductase Sterol 24-C- methyltransferase C-8 sterol isomerase C-5 sterol desaturase C-22 sterol desaturase C-24 sterol reductase Acetoacetyl-CoA Acetyl-CoA CoA H 2 O 3-Hydroxy-3-methylglutaryl-CoA CoA Mevalonic acid ATP Mevalonic acid-5P ADP ATP ADP (S)-5-Diphosphomevalonic acid ATP ADP P i Isopentenyl pyrophosphate CO 2 Dimethylallylpyrophosphate Geranyl-PP PP i Farnesyl pyrophosphate PP i NADPH Squalene NADP PP i O 2 NADPH (S)-2,3- Epoxysqualene H 2 O NADP Lanosterin NADPH 24,25- Dihydrolanosterol NADP O 2 NADPH 4,4- Dimethylcholesta- 8,14,24- trienol Formic acid NADP H 2 O NADPH 4,4-Dimethyl- 5a-cholesta- 8,24-dien-3- b-ol NADP NADPH NADP CoA H + O 2 NADPH 4α- hydroxymethyl- 4β-methyl-5α- cholesta- 8,24-dien-3β- ol NADP H 2 O H + O 2 NADPH 4α-formyl-4β- methyl-5α- cholesta- 8,24-dien-3β- ol H 2 O NADP O 2 NADPH 4β-methyl-4α- carboxy- cholesta- 8,24-dien-3β- ol H 2 O NADP NADP 3-Keto-4- methylzymosterol CO 2 NADPH NADPH H + NADP 4a- Methylzymosterol H + O 2 NADPH H 2 O NADP 4α- hydroxymethyl- 5α-cholesta- 8,24-dien-3β- ol H + O 2 NADPH 4α-formyl-5α- cholesta- 8,24-dien-3β- ol H 2 O NADP O 2 NADPH 4α-carboxy- 5α-cholesta- 8,24-dien-3β- ol H 2 O NADP NADP 5α-cholesta- 8,24-dien-3- one CO 2 NADPH NADPH H + Zymosterol NADP S- Adenosylmethionine fecosterol S- Adenosylhomocysteine H + Episterol H + O 2 ferrocytochrome c 5,7,24(28)- Ergostatrienol H 2 O ferricytochrome c H + NADPH O 2 ergosta- 5,7,22,24(28)- tetraen-3-β- ol NADP H 2 O H + NADPH Ergosterol NADP Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium FAD FAD Heme Butyrate Metabolism Pyruvate Metabolism Valine, Leucine, and Isoleucine Degradation Tryptophan Metabolism Pyruvate Metabolism Fatty Acid Metabolism Endoplasmic Reticulum Peroxisome Peroxisome Intracellular Space Extracellular Space Endoplasmic Reticulum Lysosome