PathWhiz

Pathway Description

Ketone Body Metabolism

Saccharomyces cerevisiae

Metabolic Pathway

The ketone body metabolism is a simple pathway that shows a reversible reaction from acetoacetyl-Coa to acetyl-CoA. Both are combined to form S-3-hydroxy-3-methylglutaryl-CoA. The latter compound can then be incorporated into the steroid biosynthesis pathway.

References

Ketone Body Metabolism References

RUDNEY H: The biosynthesis of beta-hydroxy-beta-methylglutaric acid. J Biol Chem. 1957 Jul;227(1):363-77.

Pubmed: 13449080

Highlighted elements will appear in red.

Highlight Compounds

	3-Hydroxy-3-methylglutaryl-CoA
	Acetoacetyl-CoA
	Acetone
	Acetyl-CoA
	Coenzyme A
	Water

Highlight Proteins

	Hydroxymethylglutaryl-CoA synthase
	Unknown

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		3-Hydroxy-3-methylglutaryl-CoA
		Acetoacetyl-CoA
		Acetone
		Acetyl-CoA
		Coenzyme A
		Water

Visualize Protein Data

		Hydroxymethylglutaryl-CoA synthase
		Unknown

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