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Branched- chain-amino- acid aminotransferase, mitochondrial Branched- chain-amino- acid aminotransferase, cytosolic ketoisocaproate decarboxylase / decarboxylase Decarboxylase alcohol dehydrogenase subunit I alcohol dehydrogenase subunit 2 Ketoleucine Ketoleucine L-Leucine Oxoglutaric acid L-Glutamic acid L-Leucine Oxoglutaric acid L-Glutamic acid H + Iso- Valeraldehyde CO 2 NADH H + NAD Isopentanol
Mitochondria BAT1 BAT2 THI3, KID1 ARO10 ADH7 ADH6 Ketoleucine Ketoleucine L-Leucine Oxoglutaric acid L-Glutamic acid L-Leucine Oxoglutaric acid L-Glutamic acid Hydrogen Ion Iso- Valeraldehyde Carbon dioxide NADH Hydrogen Ion NAD Isopentanol