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1.0 17215924 ChemSpider 6022 PubChem-compound 74465-19-3 CAS 937 ChemSpider C6H17O21P5 Inositol 1,3,4,5,6-pentakisphosphate 579.895 1.0 SMILES O 391520 ChemSpider 1.0 46173206 PubChem-compound HMDB0000538 HMDB C04006 KEGG Compound ATP BioCyc SMP0002394 SMPDB 1.0 1.0 Unknown Adenosine diphosphate P38710 UniProt ADP BioCyc SMP0002397 SMPDB SMILES OP([O-])(=O)OP([O-])(=O)OC1C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C1OP([O-])([O-])=O 5743 ChemSpider BTO:0000759 BRENDA TISSUE ONTOLOGY 3.1.3.56 false 3.1.3.56 Inositol 1,4,5-trisphosphate + Water → 1D-Myo-inositol 1,4-bisphosphate + Phosphate LEFT_TO_RIGHT 1.0 SMILES [H][C@@]1(OP([O-])([O-])=O)[C@]([H])(OP([O-])([O-])=O)[C@]([H])(OP(O)(=O)OP([O-])([O-])=O)[C@@]([H])(OP([O-])([O-])=O)[C@]([H])(OP([O-])(=O)OP([O-])([O-])=O)[C@@]1([H])OP([O-])([O-])=O SMILES [H][C@]1(OP([O-])([O-])=O)[C@@]([H])(OP([O-])([O-])=O)[C@@]([H])(OP(O)(=O)OP([O-])([O-])=O)[C@]([H])(OP([O-])([O-])=O)[C@@]([H])(OP([O-])(=O)OP([O-])([O-])=O)[C@]1([H])OP([O-])([O-])=O 5742 ChemSpider 1038 PubChem-compound 1.0 CHEBI:16595 ChEBI GO:0005829 GENE ONTOLOGY 2.7.1.151 false 2.7.1.151 2 Adenosine triphosphate + Inositol 1,4,5-trisphosphate → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine diphosphate LEFT_TO_RIGHT HMDB0001401 HMDB 148077-18-3 CAS C6H19O27P7 5-Diphosphoinositol pentakisphosphate 739.8277 2.7.1.151 false 2.7.1.151 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine triphosphate → 2 Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate LEFT_TO_RIGHT MYO-INOSITOL BioCyc 85166-31-0 CAS 17216357 ChemSpider SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O C6H18O24P6 Myo-inositol hexakisphosphate 659.8614 C6H13O9P Myo-inositol 1-phosphate 260.02972 C6H12O6 myo-Inositol 180.06339 O4P Phosphate 94.95342 1D-myo-Inositol 3-phosphate BiologicalState212 Saccharomyces cerevisiae, Liver 2.0 1.0 Unknown 1010 ChemSpider Saccharomyces cerevisiae Reaction7008 false Myo-inositol hexakisphosphate + Water → Inositol 1,3,4,5,6-pentakisphosphate + Phosphate LEFT_TO_RIGHT SubPathwayInteraction3781 SubPathway3781Reaction SubPathwayReaction 1.0 10333900 ChemSpider 87-89-8 CAS 2.7.1.158 false 2.7.1.158 Adenosine triphosphate + Inositol 1,3,4,5,6-pentakisphosphate → Adenosine diphosphate + Myo-inositol hexakisphosphate LEFT_TO_RIGHT 2.7.4.21 false 2.7.4.21 Adenosine triphosphate + Myo-inositol hexakisphosphate → 5-Diphosphoinositol pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT C6H7O27P7 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate 727.74036 Inositol 1,3,4,5,6-pentakisphosphate C6H7O30P8 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate 806.69946 CHEBI:17268 ChEBI 10239179 ChemSpider 1.0 Hydrogen Ion C6H7O30P8 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate 806.69946 Cytosol 1.0 myo-Inositol C01204 KEGG Compound Q06667 UniProt Adenosine triphosphate HMDB0000211 HMDB SMILES OP(O)(=O)O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(=O)OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O HMDB0000213 HMDB SMILES [O-]P([O-])([O-])=O Reaction7034 false 1-Diphosinositol pentakisphosphate + Adenosine triphosphate → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT 1-L-MYO-INOSITOL-1-P BioCyc Reaction7033 false Adenosine triphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate → 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT 1-Diphosinositol pentakisphosphate Reaction7036 false 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT CHEBI:17816 ChEBI Reaction7035 false 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT inositol_1,4,5-trisphosphate BioCyc Reaction7037 false 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + Adenosine triphosphate → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT SMILES OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O C00009 KEGG Compound C00008 KEGG Compound 2831-74-5 CAS 2.7.1.158 false 2.7.1.158 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → Adenosine diphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate LEFT_TO_RIGHT 1D-Myo-inositol 1,4,5,6-tetrakisphosphate inositol polyphosphate kinase Reaction7032 false Adenosine triphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate → 5-Diphosphoinositol pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT 2.7.4.21 false 2.7.4.21 Adenosine triphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate → 1-Diphosinositol pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT C00001 KEGG Compound HMDB0001429 HMDB SMILES O[C@H]1[C@H](O)[C@H](O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1O SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O Inositol polyphosphate multikinase 1.0 CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound CHEBI:16067 ChEBI 388562 ChemSpider Liver C6H16O18P4 1D-Myo-inositol 1,4,5,6-tetrakisphosphate 499.9287 121010-58-0 CAS GO:0005634 GENE ONTOLOGY Reaction7024 false Myo-inositol 1-phosphate + Water → Phosphate + myo-Inositol LEFT_TO_RIGHT Reaction7027 false 1D-myo-Inositol 3-phosphate + Water → Phosphate + myo-Inositol LEFT_TO_RIGHT 1.0 Reaction7029 false Inositol 1,3,4,5,6-pentakisphosphate + Water → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + Phosphate LEFT_TO_RIGHT 5.5.1.4 false 5.5.1.4 Glucose 6-phosphate → 1D-myo-Inositol 3-phosphate LEFT_TO_RIGHT 1.0 2.0 1.0 C01220 KEGG Compound C00137 KEGG Compound HMDB0003502 HMDB 2.0 5958 PubChem-compound 5957 PubChem-compound 83-86-3 CAS CHEBI:62922 ChEBI P40559 UniProt H Hydrogen Ion 1.007825 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51 PW002498 PathWhiz 1.0 56-65-5 CAS PW002495 PathWhiz Adenosine diphosphate Adenosine triphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 C6H15O15P3 Inositol 1,4,5-trisphosphate 419.96237 Inositol 1,4,5-trisphosphate HMDB0006229 HMDB 440194 PubChem-compound Endoplasmic Reticulum Membrane 46173277 PubChem-compound CPD-8587 BioCyc 443266 PubChem-compound CHEBI:30164 ChEBI C01245 KEGG Compound Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51 Inositol polyphosphate multikinase C6H13O9P Glucose 6-phosphate 260.02972 inositol polyphosphate kinase HMDB0001341 HMDB Inositol monophosphatase 1 HMDB0003529 HMDB CHEBI:18169 ChEBI Inositol polyphosphate multikinase SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O ReactionCatalysis6989 ACTIVATION Adenosine diphosphate 389182 ChemSpider Myo-inositol 1-phosphate C11174 KEGG Compound ReactionCatalysis6986 ACTIVATION ReactionCatalysis6985 ACTIVATION ReactionCatalysis6984 ACTIVATION CHEBI:15422 ChEBI Phosphate 5-Diphosphoinositol pentakisphosphate C6H13O9P 1D-myo-Inositol 3-phosphate 260.02972 7732-18-5 CAS HMDB0012494 HMDB 1.0 CHEBI:4170 ChEBI 1.0 SMILES O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O HMDB0006814 HMDB Water 439456 PubChem-compound ReactionCatalysis6999 ACTIVATION GO:0005789 GENE ONTOLOGY C6H14O12P2 1D-Myo-inositol 1,4-bisphosphate 339.99606 ReactionCatalysis6997 ACTIVATION 1.0 Water C6H19O27P7 1-Diphosinositol pentakisphosphate 739.8277 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate 1.0 C10H16N5O13P3 Adenosine triphosphate 506.99576 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate 1.0 892 PubChem-compound 890 PubChem-compound CHEBI:16761 ChEBI 1D-Myo-inositol 1,4,5,6-tetrakisphosphate HMDB0001498 HMDB GLC-6-P BioCyc 2.0 1.0 C01284 KEGG Compound HMDB0004527 HMDB 1.0 Unknown 1.0 962 PubChem-compound Myo-inositol hexakisphosphate Glucose 6-phosphate 5800 ChemSpider HMDB0000968 HMDB 5-Diphosphoinositol pentakisphosphate SMILES OC1[C@H](O)[C@H](O)C(OP(O)(O)=O)[C@@H](O)[C@@H]1O C00080 KEGG Compound C11526 KEGG Compound 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1OP(O)(O)=O HMDB0002111 HMDB SMILES OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(=O)OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O CHEBI:15377 ChEBI 14265-44-2 CAS CHEBI:15378 ChEBI SMILES [H+] 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1D-Myo-inositol 1,4,5,6-tetrakisphosphate Phosphate C00092 KEGG Compound 20298-95-7 CAS 1.0 1.0 Inositol monophosphatase 1 Inositol 1,3,4,5,6-pentakisphosphate CHEBI:17401 ChEBI 4932 TAXONOMY Myo-inositol hexakisphosphate 1D-Myo-inositol 1,4-bisphosphate 56-73-5 CAS MI-HEXAKISPHOSPHATE BioCyc Unknown H2O Water 18.010565 17216032 ChemSpider ReactionCatalysis7005 ACTIVATION Inositol Phosphate Metabolism ReactionCatalysis7002 ACTIVATION ReactionCatalysis7009 ACTIVATION ReactionCatalysis7008 ACTIVATION Inositol Metabolism SubPathway Nucleus ReactionCatalysis7007 ACTIVATION ReactionCatalysis7006 ACTIVATION CHEBI:16322 ChEBI 1061 PubChem-compound 86289440 PubChem-compound ReactionCatalysis7012 ACTIVATION HMDB0059597 HMDB ReactionCatalysis7011 ACTIVATION ReactionCatalysis7010 ACTIVATION P07250 UniProt 26332921 ChemSpider 1.0 866 ChemSpider Adenosine triphosphate SMILES O[C@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O 1.0 INOSITOL-1,4-BISPHOSPHATE BioCyc Inositol 1,4,5-trisphosphate ReactionCatalysis7015 ACTIVATION ReactionCatalysis7014 ACTIVATION ReactionCatalysis7013 ACTIVATION C11555 KEGG Compound Inositol polyphosphate multikinase Inositol- pentakisphosphate 2-kinase Multiple inositol polyphosphate phosphatase 1 Inositol polyphosphate multikinase Inositol polyphosphate multikinase Phosphatidylinositol 4,5- bisphosphate 5-phosphatase INP51 Inositol monophosphatase 1 Inositol monophosphatase 1 Inositol-3- phosphate synthase 1 Multiple inositol polyphosphate phosphatase 1 inositol polyphosphate kinase Inositol polyphosphate multikinase Inositol polyphosphate multikinase Inositol polyphosphate multikinase Inositol polyphosphate multikinase Inositol polyphosphate multikinase Inositol polyphosphate multikinase Inositol polyphosphate multikinase Myo-inositol hexakisphosphate ATP 5-Diphosphoinositol pentakisphosphate ADP Inositol 1,3,4,5,6-pentakisphosphate ATP ADP H 2 O P i ATP 1D-Myo-inositol 1,4,5,6-tetrakisphosphate ADP ATP Inositol 1,4,5-trisphosphate ADP H 2 O 1D-Myo-inositol 1,4-bisphosphate P i Myo-inositol 1-phosphate H 2 O myo-Inositol P i 1D-myo-Inositol 3-phosphate H 2 O P i Glucose 6-phosphate H 2 O P i ATP Myo-inositol hexakisphosphate ADP H + ATP H + 1- Diphosinositol pentakisphosphate ADP ATP H + 5- Diphosphoinositol pentakisphosphate ADP ATP H + 3-diphospho- 1D-myo- inositol 1,2,4,5,6- pentakisphosphate ADP ATP 1D-myo-inositol 1,5- bis(diphosphate) 2,3,4,6- tetrakisphosphate ADP ATP 1D-myo-inositol 1,5- bis(diphosphate) 2,3,4,6- tetrakisphosphate ADP ATP 3,5- bisdiphosphoinositol- 1D-myo- inositol 2,3,4,6- tetrakisphosphate ADP ATP 3,5- bisdiphosphoinositol- 1D-myo- inositol 2,3,4,6- tetrakisphosphate ADP Magnesium Magnesium NAD Inositol Metabolism Nucleoplasma Nucleus Endoplasmic Reticulum Intracellular Space
1.0 17215924 ChemSpider 6022 PubChem-compound 74465-19-3 CAS 937 ChemSpider C6H17O21P5 Inositol 1,3,4,5,6-pentakisphosphate 579.895 1.0 SMILES O 391520 ChemSpider 1.0 46173206 PubChem-compound HMDB0000538 HMDB C04006 KEGG Compound ATP BioCyc SMP0002394 SMPDB 1.0 1.0 Unknown Adenosine diphosphate P38710 UniProt ADP BioCyc SMP0002397 SMPDB SMILES OP([O-])(=O)OP([O-])(=O)OC1C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C1OP([O-])([O-])=O 5743 ChemSpider BTO:0000759 BRENDA TISSUE ONTOLOGY 3.1.3.56 false 3.1.3.56 Inositol 1,4,5-trisphosphate + Water → 1D-Myo-inositol 1,4-bisphosphate + Phosphate LEFT_TO_RIGHT 1.0 SMILES [H][C@@]1(OP([O-])([O-])=O)[C@]([H])(OP([O-])([O-])=O)[C@]([H])(OP(O)(=O)OP([O-])([O-])=O)[C@@]([H])(OP([O-])([O-])=O)[C@]([H])(OP([O-])(=O)OP([O-])([O-])=O)[C@@]1([H])OP([O-])([O-])=O SMILES [H][C@]1(OP([O-])([O-])=O)[C@@]([H])(OP([O-])([O-])=O)[C@@]([H])(OP(O)(=O)OP([O-])([O-])=O)[C@]([H])(OP([O-])([O-])=O)[C@@]([H])(OP([O-])(=O)OP([O-])([O-])=O)[C@]1([H])OP([O-])([O-])=O 5742 ChemSpider 1038 PubChem-compound 1.0 CHEBI:16595 ChEBI GO:0005829 GENE ONTOLOGY 2.7.1.151 false 2.7.1.151 2 Adenosine triphosphate + Inositol 1,4,5-trisphosphate → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine diphosphate LEFT_TO_RIGHT HMDB0001401 HMDB 148077-18-3 CAS C6H19O27P7 5-Diphosphoinositol pentakisphosphate 739.8277 2.7.1.151 false 2.7.1.151 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine triphosphate → 2 Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate LEFT_TO_RIGHT MYO-INOSITOL BioCyc 85166-31-0 CAS 17216357 ChemSpider SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O C6H18O24P6 Myo-inositol hexakisphosphate 659.8614 C6H13O9P Myo-inositol 1-phosphate 260.02972 C6H12O6 myo-Inositol 180.06339 O4P Phosphate 94.95342 1D-myo-Inositol 3-phosphate BiologicalState212 Saccharomyces cerevisiae, Liver 2.0 1.0 Unknown 1010 ChemSpider Saccharomyces cerevisiae Reaction7008 false Myo-inositol hexakisphosphate + Water → Inositol 1,3,4,5,6-pentakisphosphate + Phosphate LEFT_TO_RIGHT SubPathwayInteraction3781 SubPathway3781Reaction SubPathwayReaction 1.0 10333900 ChemSpider 87-89-8 CAS 2.7.1.158 false 2.7.1.158 Adenosine triphosphate + Inositol 1,3,4,5,6-pentakisphosphate → Adenosine diphosphate + Myo-inositol hexakisphosphate LEFT_TO_RIGHT 2.7.4.21 false 2.7.4.21 Adenosine triphosphate + Myo-inositol hexakisphosphate → 5-Diphosphoinositol pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT C6H7O27P7 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate 727.74036 Inositol 1,3,4,5,6-pentakisphosphate C6H7O30P8 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate 806.69946 CHEBI:17268 ChEBI 10239179 ChemSpider 1.0 Hydrogen Ion C6H7O30P8 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate 806.69946 Cytosol 1.0 myo-Inositol C01204 KEGG Compound Q06667 UniProt Adenosine triphosphate HMDB0000211 HMDB SMILES OP(O)(=O)O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(=O)OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O HMDB0000213 HMDB SMILES [O-]P([O-])([O-])=O Reaction7034 false 1-Diphosinositol pentakisphosphate + Adenosine triphosphate → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT 1-L-MYO-INOSITOL-1-P BioCyc Reaction7033 false Adenosine triphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate → 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT 1-Diphosinositol pentakisphosphate Reaction7036 false 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT CHEBI:17816 ChEBI Reaction7035 false 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT inositol_1,4,5-trisphosphate BioCyc Reaction7037 false 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + Adenosine triphosphate → 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT SMILES OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O C00009 KEGG Compound C00008 KEGG Compound 2831-74-5 CAS 2.7.1.158 false 2.7.1.158 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → Adenosine diphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate LEFT_TO_RIGHT 1D-Myo-inositol 1,4,5,6-tetrakisphosphate inositol polyphosphate kinase Reaction7032 false Adenosine triphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate → 5-Diphosphoinositol pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT 2.7.4.21 false 2.7.4.21 Adenosine triphosphate + Hydrogen Ion + Myo-inositol hexakisphosphate → 1-Diphosinositol pentakisphosphate + Adenosine diphosphate LEFT_TO_RIGHT C00001 KEGG Compound HMDB0001429 HMDB SMILES O[C@H]1[C@H](O)[C@H](O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1O SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O Inositol polyphosphate multikinase 1.0 CHEBI:18367 ChEBI 1032 ChemSpider C00002 KEGG Compound CHEBI:16067 ChEBI 388562 ChemSpider Liver C6H16O18P4 1D-Myo-inositol 1,4,5,6-tetrakisphosphate 499.9287 121010-58-0 CAS GO:0005634 GENE ONTOLOGY Reaction7024 false Myo-inositol 1-phosphate + Water → Phosphate + myo-Inositol LEFT_TO_RIGHT Reaction7027 false 1D-myo-Inositol 3-phosphate + Water → Phosphate + myo-Inositol LEFT_TO_RIGHT 1.0 Reaction7029 false Inositol 1,3,4,5,6-pentakisphosphate + Water → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + Phosphate LEFT_TO_RIGHT 5.5.1.4 false 5.5.1.4 Glucose 6-phosphate → 1D-myo-Inositol 3-phosphate LEFT_TO_RIGHT 1.0 2.0 1.0 C01220 KEGG Compound C00137 KEGG Compound HMDB0003502 HMDB 2.0 5958 PubChem-compound 5957 PubChem-compound 83-86-3 CAS CHEBI:62922 ChEBI P40559 UniProt H Hydrogen Ion 1.007825 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51 PW002498 PathWhiz 1.0 56-65-5 CAS PW002495 PathWhiz Adenosine diphosphate Adenosine triphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 C6H15O15P3 Inositol 1,4,5-trisphosphate 419.96237 Inositol 1,4,5-trisphosphate HMDB0006229 HMDB 440194 PubChem-compound Endoplasmic Reticulum Membrane 46173277 PubChem-compound CPD-8587 BioCyc 443266 PubChem-compound CHEBI:30164 ChEBI C01245 KEGG Compound Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51 Inositol polyphosphate multikinase C6H13O9P Glucose 6-phosphate 260.02972 inositol polyphosphate kinase HMDB0001341 HMDB Inositol monophosphatase 1 HMDB0003529 HMDB CHEBI:18169 ChEBI Inositol polyphosphate multikinase SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O ReactionCatalysis6989 ACTIVATION Adenosine diphosphate 389182 ChemSpider Myo-inositol 1-phosphate C11174 KEGG Compound ReactionCatalysis6986 ACTIVATION ReactionCatalysis6985 ACTIVATION ReactionCatalysis6984 ACTIVATION CHEBI:15422 ChEBI Phosphate 5-Diphosphoinositol pentakisphosphate C6H13O9P 1D-myo-Inositol 3-phosphate 260.02972 7732-18-5 CAS HMDB0012494 HMDB 1.0 CHEBI:4170 ChEBI 1.0 SMILES O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O HMDB0006814 HMDB Water 439456 PubChem-compound ReactionCatalysis6999 ACTIVATION GO:0005789 GENE ONTOLOGY C6H14O12P2 1D-Myo-inositol 1,4-bisphosphate 339.99606 ReactionCatalysis6997 ACTIVATION 1.0 Water C6H19O27P7 1-Diphosinositol pentakisphosphate 739.8277 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate 1.0 C10H16N5O13P3 Adenosine triphosphate 506.99576 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate 1.0 892 PubChem-compound 890 PubChem-compound CHEBI:16761 ChEBI 1D-Myo-inositol 1,4,5,6-tetrakisphosphate HMDB0001498 HMDB GLC-6-P BioCyc 2.0 1.0 C01284 KEGG Compound HMDB0004527 HMDB 1.0 Unknown 1.0 962 PubChem-compound Myo-inositol hexakisphosphate Glucose 6-phosphate 5800 ChemSpider HMDB0000968 HMDB 5-Diphosphoinositol pentakisphosphate SMILES OC1[C@H](O)[C@H](O)C(OP(O)(O)=O)[C@@H](O)[C@@H]1O C00080 KEGG Compound C11526 KEGG Compound 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1OP(O)(O)=O HMDB0002111 HMDB SMILES OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(=O)OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O CHEBI:15377 ChEBI 14265-44-2 CAS CHEBI:15378 ChEBI SMILES [H+] 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1D-Myo-inositol 1,4,5,6-tetrakisphosphate Phosphate C00092 KEGG Compound 20298-95-7 CAS 1.0 1.0 Inositol monophosphatase 1 Inositol 1,3,4,5,6-pentakisphosphate CHEBI:17401 ChEBI 4932 TAXONOMY Myo-inositol hexakisphosphate 1D-Myo-inositol 1,4-bisphosphate 56-73-5 CAS MI-HEXAKISPHOSPHATE BioCyc Unknown H2O Water 18.010565 17216032 ChemSpider ReactionCatalysis7005 ACTIVATION Inositol Phosphate Metabolism ReactionCatalysis7002 ACTIVATION ReactionCatalysis7009 ACTIVATION ReactionCatalysis7008 ACTIVATION Inositol Metabolism SubPathway Nucleus ReactionCatalysis7007 ACTIVATION ReactionCatalysis7006 ACTIVATION CHEBI:16322 ChEBI 1061 PubChem-compound 86289440 PubChem-compound ReactionCatalysis7012 ACTIVATION HMDB0059597 HMDB ReactionCatalysis7011 ACTIVATION ReactionCatalysis7010 ACTIVATION P07250 UniProt 26332921 ChemSpider 1.0 866 ChemSpider Adenosine triphosphate SMILES O[C@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O 1.0 INOSITOL-1,4-BISPHOSPHATE BioCyc Inositol 1,4,5-trisphosphate ReactionCatalysis7015 ACTIVATION ReactionCatalysis7014 ACTIVATION ReactionCatalysis7013 ACTIVATION C11555 KEGG Compound