The riboneogenesis pathway is in charge of converting 3 carbon units into ribose. This pathway involves the conversion of fructose 6 phosphate which can be derived from the gluconeogenesis pathway. Fructose 6 phosphate reacts with a glyceraldehyde 3 phosphate through a transketolase resulting in the release of erythrose 4 phosphate and xylulose 5 phosphate. Erythrose 4 phosphate reacts with a dihydroxyacetone phosphate resulting in a release of sedoheptulose 1,7-biphosphate. Sedoheptulose 1,7-biphosphate is transformed by SHB17 resulting in the release of sedoheptulose 7 phosphate and a phosphate. Sedoheptulose 7 phosphate reacts with a glyceraldehyde 3 phosphate through a transketolase resulting in the release of xylulose 5 phosphate and ribose 5 phosphate. Ribose 5 phosphate can react with reversibly through a ribose 5 phosphate ketol-isomerase resulting in the release of ribulose 5 phosphate. Xylulose 5 phosphate can react reversibly through a ribulose 5 phosphate 3-epimerase resulting in the release of ribulose 5 phosphate.

Riboneogenesis References