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Pathway Description
Lysolipid Incorporation into Mitochondria PC(16:0/16:0)
Saccharomyces cerevisiae
Metabolic Pathway
Lysolipids such as lysophosphatidylethanolamine, lysophosphatidylcholine, lysophosphatidylserine and lysophosphatidylinositol get transported into the cell through a phospholipid ATPase. Once in the cytosol they are incorporated into the mitochondria membrane through a Ale1p transport membrane where phosphatidylcholine is generated.
References
Lysolipid Incorporation into Mitochondria PC(16:0/16:0) References
Riekhof WR, Wu J, Gijon MA, Zarini S, Murphy RC, Voelker DR: Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem. 2007 Dec 21;282(51):36853-61. doi: 10.1074/jbc.M706718200. Epub 2007 Oct 21.
Pubmed: 17951629
This pathway was generated using PathWhiz -
Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.
Generated from PW002531
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