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Pathway Description
Phosphatidylcholine Biosynthesis PC(14:1(11Z)/20:1(13Z))
Saccharomyces cerevisiae
Metabolic Pathway
Phosphatidyl ethanolamine reacts with S-adenosylmethionine through a phosphatdylethanolamine N-methyltransferase resulting in the release of hydrogen ion and S-adenosylhomocysteine an a PE-NMe. The PE-NMe reacts with S'-adenosylmethionine through a phosphotidyl-N-methylethanolamine N-methyltransferase resulting in the release of hydrogen ion, s-adenosylhomocysteine and PE-NMe2. The PE-NMe2 reacts with s-adenosylmethionine through a phosphotidyl-N-methylethanolamine N-methyltransferase resuilting in the release of hydrogen ion, s-adenosylhomocysteine and PC
References
Phosphatidylcholine Biosynthesis PC(14:1(11Z)/20:1(13Z)) References
Aktas M, Wessel M, Hacker S, Klusener S, Gleichenhagen J, Narberhaus F: Phosphatidylcholine biosynthesis and its significance in bacteria interacting with eukaryotic cells. Eur J Cell Biol. 2010 Dec;89(12):888-94. doi: 10.1016/j.ejcb.2010.06.013. Epub 2010 Jul 24.
Pubmed: 20656373
Bolognese CP, McGraw P: The isolation and characterization in yeast of a gene for Arabidopsis S-adenosylmethionine:phospho-ethanolamine N-methyltransferase. Plant Physiol. 2000 Dec;124(4):1800-13. doi: 10.1104/pp.124.4.1800.
Pubmed: 11115895
Boumann HA, de Kroon AI: The contributions of biosynthesis and acyl chain remodelling to the molecular species profile of phosphatidylcholine in yeast. Biochem Soc Trans. 2005 Nov;33(Pt 5):1146-9. doi: 10.1042/BST20051146.
Pubmed: 16246068
This pathway was generated using PathWhiz -
Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.
Generated from PW002720
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