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Solute carrier family 15 member 1 Solute carrier family 15 member 1 Amine oxidase [flavin- containing] A Aldehyde dehydrogenase, mitochondrial 2-amino-3- ketobutyrate coenzyme A ligase, mitochondrial Glycine dehydrogenase [decarboxylating], mitochondrial Aminomethyltransferase, mitochondrial Serine hydroxymethyltransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Serine-- pyruvate aminotransferase Serine-- pyruvate aminotransferase Glycine amidinotransferase, mitochondrial Guanidinoacetate N- methyltransferase 5- aminolevulinate synthase, nonspecific, mitochondrial Betaine-- homocysteine S- methyltransferase 1 Glycerate kinase D-3- phosphoglycerate dehydrogenase Phosphoserine aminotransferase Phosphoserine phosphatase L-serine dehydratase/L- threonine deaminase Serine hydroxymethyltransferase, cytosolic Serine racemase Cystathionine beta-synthase Serine--tRNA ligase, cytoplasmic Glycine--tRNA ligase Cystathionine gamma-lyase Glycine N- methyltransferase L-Cysteine 3-Phosphoglyceric acid Pyruvic acid Pyruvic acid Pyruvic acid L-Serine Sarcosine Aminoacetone O2 H2O NH3 H2O2 Pyruvaldehyde NAD NADH H2O L-2-Amino-3-oxobutanoic acid CO2 Acetyl-CoA Glycine CoA Dimethylglycine H2O Formaldehyde Formaldehyde (R)-lipoic acid 8-[(Aminomethyl)sulfanyl]-6- sulfanyloctanoic acid CO2 Dihydrolipoate NH3 5,10-Methylene-THF Glycine H2O Tetrahydrofolic acid L-Serine NAD NADH Hydroxypyruvic acid L-Alanine Glyoxylic acid L-Arginine Guanidoacetic acid Orotidylic acid S-Adenosylhomocysteine S-Adenosylmethionine Creatine Succinyl-CoA 5-Aminolevulinic acid CoA βine Homocysteine L-Methionine Glyceric acid ATP ADP NAD Phosphohydroxypyruvic acid NADH L-Glutamic acid Phosphoserine Oxoglutaric acid H2O Pi NH3 Tetrahydrofolic acid Glycine 5,10-Methylene-THF H2O D-Serine Homocysteine L-Cystathionine H2O ATP AMP PPi ATP AMP PPi H2O 2-Ketobutyric acid NH3 S-Adenosylhomocysteine S-Adenosylmethionine FAD Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate FAD Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Magnesium Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate L-Seryl-tRNA L-Seryl- tRNA(Ser) Glycyl-tRNA Glycyl- tRNA(Gly) Sarcosine dehydrogenase, mitochondrial Cysteine Metabolism Gluconeogenesis Glycolysis Pyruvate Metabolism Pyruvate Metabolism Pyruvate Metabolism Sphingolipid Metabolism Dimethylglycine dehydrogenase, mitochondrial Sarcosine H2O FAD FAD Pyridoxal 5'-phosphate Zinc (II) ion Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Cytosol Mitochondria Outer mitochondria membrane Inner mitochondria membrane Mitochondria matrix Mental and motor retardation Visual Impairment Cardiomyopathy
Mitochondria SLC15A1 SLC15A1 MAOA ALDH2 GCAT GLDC AMT SHMT2 DLD AGXT AGXT GATM GAMT ALAS1 BHMT GLYCTK PHGDH PSAT1 PSPH SDS SHMT1 SRR CBS SARS GARS CTH GNMT L-Cysteine 3- Phosphoglyceric acid Pyruvic acid Pyruvic acid Pyruvic acid L-Serine Sarcosine Aminoacetone Oxygen Water Ammonia Hydrogen peroxide Pyruvaldehyde NAD NADH Water L-2-Amino-3- oxobutanoic acid Carbon dioxide Acetyl-CoA Glycine Coenzyme A Dimethylglycine Water Formaldehyde Formaldehyde (R)-lipoic acid 8- [(Aminomethyl)sulfanyl]- 6- sulfanyloctanoic acid Carbon dioxide Dihydrolipoate Ammonia 5,10- Methylene-THF Glycine Water Tetrahydrofolic acid L-Serine NAD NADH Hydroxypyruvic acid L-Alanine Glyoxylic acid L-Arginine Guanidoacetic acid Orotidylic acid S- Adenosylhomocysteine S- Adenosylmethionine Creatine Succinyl-CoA 5- Aminolevulinic acid Coenzyme A βine Homocysteine L-Methionine Glyceric acid Adenosine triphosphate Adenosine diphosphate NAD Phosphohydroxypyruvic acid NADH L-Glutamic acid Phosphoserine Oxoglutaric acid Water Phosphate Ammonia Tetrahydrofolic acid Glycine 5,10- Methylene-THF Water D-Serine Homocysteine L-Cystathionine Water Adenosine triphosphate Adenosine monophosphate Pyrophosphate Adenosine triphosphate Adenosine monophosphate Pyrophosphate Water 2-Ketobutyric acid Ammonia S- Adenosylhomocysteine S- Adenosylmethionine L-Seryl-tRNA L-Seryl- tRNA(Ser) Glycyl-tRNA Glycyl- tRNA(Gly) SARDH Cysteine Metabolism Gluconeogenesis Glycolysis Pyruvate Metabolism Pyruvate Metabolism Pyruvate Metabolism Sphingolipid Metabolism DMGDH Sarcosine Water
SLC15A1 SLC15A1 MAOA ALDH2 GCAT GLDC AMT SHMT2 DLD AGXT AGXT GATM GAMT ALAS1 BHMT GLYCTK PHGDH PSAT1 PSPH SDS SHMT1 SRR CBS SARS GARS CTH GNMT Cys G3P Pyr Pyr Pyr Ser Sar Amnactn O2 H2O NH3 H2O2 Pyruval NAD NADH H2O L2AAA CO2 Ac-CoA Gly CoA DMglyc H2O Formol Formol Lipoate 8As6SA CO2 Dhlip NH3 5XM-THF Gly H2O THFA Ser NAD NADH OH-Pyr Ala Glyoxal Arg GIAA OMP SAH SAMe Creatin Suc-CoA 5-Amnva CoA βine Hcys Met Glycera ATP ADP NAD 3POHPyr NADH Glu SEP AKG H2O Pi NH3 THFA Gly 5XM-THF H2O D-Ser Hcys L-Cystt H2O ATP AMP PPi ATP AMP PPi H2O 2KBA NH3 SAH SAMe FAD Pyr-5'P Pyr-5'P Pyr-5'P FAD Pyr-5'P Pyr-5'P Mg2+ Pyr-5'P Pyr-5'P Pyr-5'P LST LSTS GT GTG SARDH PW000018 PW000152 PW000146 PW000054 PW000054 PW000054 PW000148 DMGDH Sar H2O FAD FAD Pyr-5'P Zinc Pyr-5'P Pyr-5'P Pyr-5'P Cytosol Mitochondria Outer mitochondria membrane Inner mitochondria membrane Mitochondria matrix Mental and motor retardation Visual Impairment Cardiomyopathy
Mitochondria SLC15A1 SLC15A1 MAOA ALDH2 GCAT GLDC AMT SHMT2 DLD AGXT AGXT GATM GAMT ALAS1 BHMT GLYCTK PHGDH PSAT1 PSPH SDS SHMT1 SRR CBS SARS GARS CTH GNMT Cys G3P Pyr Pyr Pyr Ser Sar Amnactn O2 H2O NH3 H2O2 Pyruval NAD NADH H2O L2AAA CO2 Ac-CoA Gly CoA DMglyc H2O Formol Formol Lipoate 8As6SA CO2 Dhlip NH3 5XM-THF Gly H2O THFA Ser NAD NADH OH-Pyr Ala Glyoxal Arg GIAA OMP SAH SAMe Creatin Suc-CoA 5-Amnva CoA βine Hcys Met Glycera ATP ADP NAD 3POHPyr NADH Glu SEP AKG H2O Pi NH3 THFA Gly 5XM-THF H2O D-Ser Hcys L-Cystt H2O ATP AMP Ppi ATP AMP Ppi H2O 2KBA NH3 SAH SAMe LST LSTS GT GTG SARDH PW000018 PW000152 PW000146 PW000054 PW000054 PW000054 PW000148 DMGDH Sar H2O