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Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Brivaracetam PIS2M1 Brivaracetam PIS2M1 Brivaracetam PIS1M1 Brivaracetam PIS1M1 Brivaracetam Brivaracetam Brivaracetam PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Brivaracetam undergoes metabolism to give Brivaracetam PIS1M1, Brivaracetam PIS1M2 and Brivaracetam PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown CYP3A4 CYP3A4 CYP3A4 Brivaracetam PIS2M1 Brivaracetam PIS2M1 Brivaracetam PIS1M1 Brivaracetam PIS1M1 Brivaracetam Brivaracetam Brivaracetam PIS1M2 Urinary Excretion and/or Bile duct Excretion