PathWhiz

PathWhiz ID	Pathway	Meta Data
PW127989 View Pathway	drug action Amifampridine Action Pathway Homo sapiens Amifampridine, also known as Firdapse, is a presynaptic voltage-gated potassium channel blocker. This drug is used to treat Lambert-Eaton myasthenic syndrome. LEMS is an auto-immune disorder of the neuromuscular junction that is characterized by proximal muscle weakness, depressed tendon reflexes, and posttetanic potentiation in addition to autonomic dysfunction. This drug blocks presynaptic fast voltage-gated potassium channels, which prolongs the action potential and increases presynaptic calcium concentrations while increasing the acetylcholine concentrations at the neuromuscular junction. Increased intracellular calcium enhances the exocytosis of acetylcholine-containing vesicles and enhances impulse transmission at the synapses. It is administered as an oral tablet. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: June 27, 2023 at 11:09 Last Updated: June 27, 2023 at 11:09
PW126978 View Pathway	metabolic Ubiquinone and other terpenoid-quinone biosynthesis 1636480163 1654322490 Hordeum vulgare BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: June 04, 2022 at 00:03 Last Updated: June 04, 2022 at 00:03
PW128016 View Pathway	metabolic Ubiquinone and other terpenoid-quinone biosynthesis 1636480163 1652153943 1688064066 Cannabis sativa BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: June 29, 2023 at 12:41 Last Updated: June 29, 2023 at 12:41
PW126990 View Pathway	metabolic Ubiquinone and other terpenoid-quinone biosynthesis 1636480163 1652153943 1654630630 Cannabis sativa BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: June 07, 2022 at 13:37 Last Updated: June 07, 2022 at 13:37
PW126908 View Pathway	metabolic Ubiquinone and other terpenoid-quinone biosynthesis 1636480163 1652153943 Cannabis sativa BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: May 09, 2022 at 21:38 Last Updated: May 09, 2022 at 21:38
PW124592 View Pathway	metabolic Ubiquinone and other terpenoid-quinone biosynthesis Cannabis sativa BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Eponine Oler Created On: March 19, 2021 at 13:05 Last Updated: March 19, 2021 at 13:05
PW124158 View Pathway	metabolic Ubiquinone and other terpenoid-quinone biosynthesis Arabidopsis thaliana BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Dorsa Yahya Rayat Created On: September 13, 2020 at 14:37 Last Updated: September 13, 2020 at 14:37
PW126404 View Pathway	drug action COX Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: November 09, 2021 at 10:49 Last Updated: November 09, 2021 at 10:49