
PathWhiz ID | Pathway | Meta Data |
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PW122495 |
Selenocompound MetabolismDanio rerio
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Creator: Eponine Oler Created On: May 01, 2019 at 11:01 Last Updated: May 01, 2019 at 11:01 |
PW122340 |
Selenocompound MetabolismDrosophila melanogaster
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Creator: Eponine Oler Created On: February 09, 2019 at 20:52 Last Updated: February 09, 2019 at 20:52 |
PW124156 |
Selenocompound metabolismArabidopsis thaliana
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Creator: Dorsa Yahya Rayat Created On: September 12, 2020 at 17:40 Last Updated: September 12, 2020 at 17:40 |
PW002472 |
Selenocompound MetabolismSaccharomyces cerevisiae
The the metabolism of selenocompounds starts with Selenocysteine being metabolized by a CGS resulting in the release of Seleno-cystathionine. The resulting compound is metabolized by a CBL resulting in the release of selenohomocysteine. The resulting compound reacts with MET resulting in the release of a seleno-methionine. Selenomethionine can be either metabolized into Seleno-methionyl-tRNA or a Methyl-selenol.
Methyl-selenol can also be the result of Methyl-selenic acid reacting with a thioredoxin reductase or Se-methyl-selenocysteine reacting through a CTH.
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Creator: miguel ramirez Created On: February 19, 2016 at 11:41 Last Updated: February 19, 2016 at 11:41 |
PW122494 |
Selenocompound MetabolismXenopus laevis
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Creator: Eponine Oler Created On: May 01, 2019 at 11:01 Last Updated: May 01, 2019 at 11:01 |
PW075771 |
Selenocompound MetabolismHomo sapiens
Selenate is the major inorganic selenocompound found in both animal and plant tissues. Selenocysteine is the predominant selenoamino acid in tissues when inorganic selenium is given to animals. Selenomethionine is the major selenocompound found initially in animals given this selenoamino acid, but is converted with time afterwards to selenocysteine. Selenomethionine is the major selenocompound in cereal grains, grassland legumes and soybeans. Selenomethionine can also be the major selenocompound in selenium enriched yeast, but the amount can vary markedly depending upon the growth conditions.
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Creator: xuan cao Created On: August 03, 2018 at 10:18 Last Updated: August 03, 2018 at 10:18 |
PW146261 |
drug action
Selenomethionine Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:48 Last Updated: October 07, 2023 at 17:48 |
PW146137 |
drug action
Selenomethionine Se-75 Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:29 Last Updated: October 07, 2023 at 17:29 |
PW128107 |
drug action
Selexipag Action PathwayHomo sapiens
Selexipag is a non-prostanoid prostacyclin receptor agonist, also known as Uptravi typically used to treat pulmonary arterial hypertension. Selexipag is a selective prostacyclin receptor agonist, it is administered orally and is metabolized by carboylesterase1 into its active metabolite (ACT-333679). The metabolite has a high selectivity for prostacyclin receptor that activates it and subsequent G coupled protein, Gs, that increases cAMP levels. Increased cAMP levels leads to inhibited platelet aggregation and activation.
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Creator: Selena Created On: July 18, 2023 at 12:12 Last Updated: July 18, 2023 at 12:12 |
PW146368 |
drug action
Selexipag Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 18:02 Last Updated: October 07, 2023 at 18:02 |