PathWhiz

PathWhiz ID	Pathway	Meta Data
PW128474 View Pathway	drug action Sulfathiazole Action Pathway Escherichia coli (strain K12) Sulfathiazole is a short-acting antibiotic from the sulfonamide drug class. This drug is mostly used with cattle because less toxic alternatives were discovered for humans. Except for vaginal use (vaginal cream), the FDA withdrew the approval of sulfathiazole products. This drug is active against a wide range of gram-positive and gram-negative bacteria. It was used for bacterial enteritis, bacterial pneumonia, ear infections, eye infections, skin ulcers, urinary tract infections, and many others. Sulfathiazole is an inhibitor of dihydropteroate synthase. This inhibition results in the inability of the bacteria to produce folic acid, thus the growth of the bacteria is inhibited (bacteriostatic). BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: August 30, 2023 at 11:30 Last Updated: August 30, 2023 at 11:30
PW145659 View Pathway	drug action Sulfathiazole Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:19 Last Updated: October 07, 2023 at 16:19
PW145226 View Pathway	drug action Sulfinpyrazone Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:21 Last Updated: October 07, 2023 at 15:21
PW176139 View Pathway	metabolic Sulfinpyrazone Predicted Metabolism Pathway new Homo sapiens Metabolites of Sulfinpyrazone are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 14:15 Last Updated: November 29, 2023 at 14:15
PW128387 View Pathway	drug action Sulfisoxazole Action Pathway Escherichia coli (strain K12) Sulfisoxazole is a short-acting antibiotic from the sulfonamide drug class. It has activity against a wide range of gram-negative and gram-positive organisms. This drug is indicated in the treatment of many infections: urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, nocardiosis, chancroid, toxoplasmosis, malaria, and many others. This drug is bacteriostatic; it inhibits the replication of bacteria by inhibiting the dihydropteroate synthase. This enzyme is responsible for one of the reactions to synthesize folic acid in bacteria by the condensation of the pteridine with para-aminobenzoic acid (PABA). This drug stops the replication of the bacteria (bacteriostatic). Sulfisoxazole is administered as an oral tablet. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: August 25, 2023 at 12:43 Last Updated: August 25, 2023 at 12:43
PW144392 View Pathway	drug action Sulfisoxazole Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:33 Last Updated: October 07, 2023 at 13:33
PW122077 View Pathway	disease Sulfite Oxidase Deficiency Rattus norvegicus Sulfite oxidase deficiency (SOD) is a disorder, an autosomal recessive disease. In classic SOD, it is usually identified a few days after the birth of an affected individual, and is recognizable through characteristic dysmorphic features, seizures, and other signs of progressive encephalopathy. Patients also have ocular lenses that are dislocated, and usually die within a few months of being born. In late- onset SOD, the disorder is identified only in the later months, usually 6-18 months, of the child’s life by a delay or regression of neurological progress. This disorder is very rare, but the actual prevalence is not known. It can be diagnosed through a sulfite test strip in urine or by a skin fibroblast culture, which will indicate an absence of sulfite oxidase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: September 10, 2018 at 15:52 Last Updated: September 10, 2018 at 15:52
PW121853 View Pathway	disease Sulfite Oxidase Deficiency Mus musculus Sulfite oxidase deficiency (SOD) is a disorder, an autosomal recessive disease. In classic SOD, it is usually identified a few days after the birth of an affected individual, and is recognizable through characteristic dysmorphic features, seizures, and other signs of progressive encephalopathy. Patients also have ocular lenses that are dislocated, and usually die within a few months of being born. In late- onset SOD, the disorder is identified only in the later months, usually 6-18 months, of the child’s life by a delay or regression of neurological progress. This disorder is very rare, but the actual prevalence is not known. It can be diagnosed through a sulfite test strip in urine or by a skin fibroblast culture, which will indicate an absence of sulfite oxidase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: September 10, 2018 at 15:50 Last Updated: September 10, 2018 at 15:50
PW127276 View Pathway	disease Sulfite Oxidase Deficiency Homo sapiens Sulfite oxidase deficiency (SOD) is a disorder, an autosomal recessive disease. In classic SOD, it is usually identified a few days after the birth of an affected individual, and is recognizable through characteristic dysmorphic features, seizures, and other signs of progressive encephalopathy. Patients also have ocular lenses that are dislocated, and usually die within a few months of being born. In late- onset SOD, the disorder is identified only in the later months, usually 6-18 months, of the child’s life by a delay or regression of neurological progress. This disorder is very rare, but the actual prevalence is not known. It can be diagnosed through a sulfite test strip in urine or by a skin fibroblast culture, which will indicate an absence of sulfite oxidase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: November 28, 2022 at 11:50 Last Updated: November 28, 2022 at 11:50
PW000508 View Pathway	disease Sulfite Oxidase Deficiency Homo sapiens Sulfite oxidase deficiency (SOD) is a disorder, an autosomal recessive disease. In classic SOD, it is usually identified a few days after the birth of an affected individual, and is recognizable through characteristic dysmorphic features, seizures, and other signs of progressive encephalopathy. Patients also have ocular lenses that are dislocated, and usually die within a few months of being born. In late- onset SOD, the disorder is identified only in the later months, usually 6-18 months, of the child’s life by a delay or regression of neurological progress. This disorder is very rare, but the actual prevalence is not known. It can be diagnosed through a sulfite test strip in urine or by a skin fibroblast culture, which will indicate an absence of sulfite oxidase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: August 29, 2013 at 10:39 Last Updated: August 29, 2013 at 10:39