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HMDB00012 HMDB HMDB00014 HMDB CHEBI:17748 ChEBI 66-22-8 CAS C00672 KEGG Compound 937 ChemSpider 1135 PubChem-compound CPD-8587 BioCyc SMILES O=C1NC=CC(=O)N1 1.0 Thymine pyrimidine deoxyribonucleosides degradation Cytidine deaminase 1.0 Water SMILES CC1=CNC(=O)NC1=O SMILES O 1.0 CHEBI:15698 ChEBI HMDB00300 HMDB 1.0 Uracil HMDB01351 HMDB HMDB00262 HMDB H4N Ammonium 18.034374 2.4.2.4 false 2.4.2.4 Deoxyuridine + Phosphate → Deoxyribose 1-phosphate + Uracil LEFT_TO_RIGHT SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O 14798-03-9 CAS Reaction6014 false Deoxycytidine + Hydrogen Ion + Water → Ammonium + Deoxyuridine LEFT_TO_RIGHT CHEBI:17568 ChEBI C9H13N3O4 Deoxycytidine 227.0906 C9H12N2O5 Deoxyuridine 228.07462 1.0 URACIL BioCyc PW002063 PathWhiz Thymidine phosphorylase 2.0 5585 ChemSpider 1038 PubChem-compound 1.0 7732-18-5 CAS C00214 KEGG Compound 1141 ChemSpider C00178 KEGG Compound GO:0005829 GENE ONTOLOGY HMDB59597 HMDB 1.0 Transport499 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport498 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT SMILES [NH4+] C00106 KEGG Compound O4P Phosphate 94.95342 1010 ChemSpider http://identifiers.org/smpdb/SMP02075 SMPDB HMDB41827 HMDB 439287 PubChem-compound Reaction6032 false Phosphate + Thymidine ↔ Deoxyribose 1-phosphate + Thymine REVERSIBLE Thymidine 962 PubChem-compound THYMIDINE BioCyc CHEBI:17821 ChEBI Ammonium Hydrogen Ion SMILES NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1 SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O Cytosol 1.0 13712 PubChem-compound 1174 PubChem-compound 13711 PubChem-compound 218 ChemSpider CHEBI:16450 ChEBI Phosphate 1.0 Nucleoside permease nupG HMDB02111 HMDB Nucleoside permease nupC C00080 KEGG Compound C5H11O7P Deoxyribose 1-phosphate 214.02425 Periplasmic Space cytidine deaminase SMILES [O-]P([O-])([O-])=O 951-77-9 CAS TransportCatalysis435 ACTIVATION TransportCatalysis434 ACTIVATION 13118 ChemSpider Cytidine deaminase 13117 ChemSpider TransportCatalysis430 ACTIVATION CHEBI:15377 ChEBI C00526 KEGG Compound C00009 KEGG Compound CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS Thymidine Hydrogen Ion 50-89-5 CAS C00881 KEGG Compound C00001 KEGG Compound thymidine phosphorylase / uracil phosphorylase 1.0 DEOXY-RIBOSE-1P BioCyc THYMINE BioCyc CHEBI:18367 ChEBI Deoxycytidine 1032 ChemSpider P0ABF6 UniProt Deoxyuridine P0AFF2 UniProt ReactionCatalysis5979 ACTIVATION 1.0 1.0 Deoxycytidine Thymidine phosphorylase HMDB01429 HMDB ReactionCatalysis5975 ACTIVATION 1103 ChemSpider 1.0 C4H4N2O2 Uracil 112.027275 16741146 PubChem-compound C01342 KEGG Compound CHEBI:28938 ChEBI 17210-42-3 CAS HMDB00273 HMDB 951-78-0 CAS P0AFF4 UniProt SMILES OC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O H2O Water 18.010565 Deoxyribose 1-phosphate C5H6N2O2 Thymine 126.04293 GO:0005620 GENE ONTOLOGY DEOXYCYTIDINE BioCyc CHEBI:28542 ChEBI H Hydrogen Ion 1.007825 1061 PubChem-compound P07650 UniProt 65-71-4 CAS Hydrogen Ion Deoxycytidine 5789 PubChem-compound DEOXYURIDINE BioCyc 388420 ChemSpider Nucleoside permease nupG 1.0 Nucleoside permease nupC TransportCatalysis429 ACTIVATION 1.0 Thymidine 2.0 Transport503 false Thymidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C10H14N2O5 Thymidine 242.09027 Transport504 false Thymidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT ReactionCatalysis5997 ACTIVATION 1.0 Nucleoside permease nupC Nucleoside permease nupG Nucleoside permease nupC Nucleoside permease nupG Cytidine deaminase Thymidine phosphorylase Thymidine phosphorylase Deoxycytidine Deoxycytidine H + H + Deoxycytidine Deoxycytidine H + H + Thymidine Thymidine H + H + Thymidine Thymidine H + H + Deoxycytidine H 2 O H + Ammonium Deoxyuridine P i Uracil Deoxyribose 1-phosphate Thymidine P i Thymine Deoxyribose 1-phosphate
HMDB00012 HMDB HMDB00014 HMDB CHEBI:17748 ChEBI 66-22-8 CAS C00672 KEGG Compound 937 ChemSpider 1135 PubChem-compound CPD-8587 BioCyc SMILES O=C1NC=CC(=O)N1 1.0 Thymine pyrimidine deoxyribonucleosides degradation Cytidine deaminase 1.0 Water SMILES CC1=CNC(=O)NC1=O SMILES O 1.0 CHEBI:15698 ChEBI HMDB00300 HMDB 1.0 Uracil HMDB01351 HMDB HMDB00262 HMDB H4N Ammonium 18.034374 2.4.2.4 false 2.4.2.4 Deoxyuridine + Phosphate → Deoxyribose 1-phosphate + Uracil LEFT_TO_RIGHT SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O 14798-03-9 CAS Reaction6014 false Deoxycytidine + Hydrogen Ion + Water → Ammonium + Deoxyuridine LEFT_TO_RIGHT CHEBI:17568 ChEBI C9H13N3O4 Deoxycytidine 227.0906 C9H12N2O5 Deoxyuridine 228.07462 1.0 URACIL BioCyc PW002063 PathWhiz Thymidine phosphorylase 2.0 5585 ChemSpider 1038 PubChem-compound 1.0 7732-18-5 CAS C00214 KEGG Compound 1141 ChemSpider C00178 KEGG Compound GO:0005829 GENE ONTOLOGY HMDB59597 HMDB 1.0 Transport499 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT Transport498 false Deoxycytidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT SMILES [NH4+] C00106 KEGG Compound O4P Phosphate 94.95342 1010 ChemSpider http://identifiers.org/smpdb/SMP02075 SMPDB HMDB41827 HMDB 439287 PubChem-compound Reaction6032 false Phosphate + Thymidine ↔ Deoxyribose 1-phosphate + Thymine REVERSIBLE Thymidine 962 PubChem-compound THYMIDINE BioCyc CHEBI:17821 ChEBI Ammonium Hydrogen Ion SMILES NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1 SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O Cytosol 1.0 13712 PubChem-compound 1174 PubChem-compound 13711 PubChem-compound 218 ChemSpider CHEBI:16450 ChEBI Phosphate 1.0 Nucleoside permease nupG HMDB02111 HMDB Nucleoside permease nupC C00080 KEGG Compound C5H11O7P Deoxyribose 1-phosphate 214.02425 Periplasmic Space cytidine deaminase SMILES [O-]P([O-])([O-])=O 951-77-9 CAS TransportCatalysis435 ACTIVATION TransportCatalysis434 ACTIVATION 13118 ChemSpider Cytidine deaminase 13117 ChemSpider TransportCatalysis430 ACTIVATION CHEBI:15377 ChEBI C00526 KEGG Compound C00009 KEGG Compound CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS Thymidine Hydrogen Ion 50-89-5 CAS C00881 KEGG Compound C00001 KEGG Compound thymidine phosphorylase / uracil phosphorylase 1.0 DEOXY-RIBOSE-1P BioCyc THYMINE BioCyc CHEBI:18367 ChEBI Deoxycytidine 1032 ChemSpider P0ABF6 UniProt Deoxyuridine P0AFF2 UniProt ReactionCatalysis5979 ACTIVATION 1.0 1.0 Deoxycytidine Thymidine phosphorylase HMDB01429 HMDB ReactionCatalysis5975 ACTIVATION 1103 ChemSpider 1.0 C4H4N2O2 Uracil 112.027275 16741146 PubChem-compound C01342 KEGG Compound CHEBI:28938 ChEBI 17210-42-3 CAS HMDB00273 HMDB 951-78-0 CAS P0AFF4 UniProt SMILES OC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O H2O Water 18.010565 Deoxyribose 1-phosphate C5H6N2O2 Thymine 126.04293 GO:0005620 GENE ONTOLOGY DEOXYCYTIDINE BioCyc CHEBI:28542 ChEBI H Hydrogen Ion 1.007825 1061 PubChem-compound P07650 UniProt 65-71-4 CAS Hydrogen Ion Deoxycytidine 5789 PubChem-compound DEOXYURIDINE BioCyc 388420 ChemSpider Nucleoside permease nupG 1.0 Nucleoside permease nupC TransportCatalysis429 ACTIVATION 1.0 Thymidine 2.0 Transport503 false Thymidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C10H14N2O5 Thymidine 242.09027 Transport504 false Thymidine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT ReactionCatalysis5997 ACTIVATION 1.0 nupC nupG nupC nupG cdd deoA deoA Deoxycytidine Deoxycytidine Hydrogen Ion Hydrogen Ion Deoxycytidine Deoxycytidine Hydrogen Ion Hydrogen Ion Thymidine Thymidine Hydrogen Ion Hydrogen Ion Thymidine Thymidine Hydrogen Ion Hydrogen Ion Deoxycytidine Water Hydrogen Ion Ammonium Deoxyuridine Phosphate Uracil Deoxyribose 1-phosphate Thymidine Phosphate Thymine Deoxyribose 1-phosphate