Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.

Loading Pathway...

CHEBI:16015 ChEBI 439161 PubChem-compound C00430 KEGG Compound Glycine--tRNA ligase L-Arginine CHEBI:30314 ChEBI Ammonia 439153 PubChem-compound 57 ChemSpider 50 ChemSpider 53481912 PubChem-compound CHEBI:20506 ChEBI CHEBI:17115 ChEBI CHEBI:16027 ChEBI Sarcosine 1.0 6137 PubChem-compound Glycine N-methyltransferase 559142 ChemSpider 1.0 1.0 P09622 UniProt CHEBI:15380 ChEBI 5742 ChemSpider NADH C25H40N7O19P3S Succinyl-CoA 867.1312 C00213 KEGG Compound CHEBI:17561 ChEBI 1.0 439175 PubChem-compound L-CYSTATHIONINE BioCyc Amine oxidase [flavin-containing] A 5736 ChemSpider C3H5O7P Phosphohydroxypyruvic acid 183.9773 5735 ChemSpider PW000157 PathWhiz CHEBI:16240 ChEBI PW000152 PathWhiz SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial Glycerate kinase Serine hydroxymethyltransferase, cytosolic C03508 KEGG Compound SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCSC(=O)CCC(O)=O 1.0 3913-50-6 CAS 979-92-0 CAS 1.0 Dimethylglycine Serine racemase 1.0 C00009 KEGG Compound C00008 KEGG Compound C00007 KEGG Compound CHEBI:17158 ChEBI C00001 KEGG Compound L-ALPHA-ALANINE BioCyc 439194 PubChem-compound SMILES OC(=O)C(=O)COP(O)(O)=O 56-41-7 CAS C00004 KEGG Compound Pyruvic acid C00003 KEGG Compound 135-16-0 CAS 1.0 2-OXOBUTANOATE BioCyc C00002 KEGG Compound Coenzyme A 1.0 Mitochondrial Inner Membrane C00019 KEGG Compound Oxygen 352-97-6 CAS 1.0 1.0 C00011 KEGG Compound C00010 KEGG Compound C00258 KEGG Compound C00014 KEGG Compound C01103 KEGG Compound C00013 KEGG Compound 1.0 6112 PubChem-compound C00022 KEGG Compound C00021 KEGG Compound 56-65-5 CAS MET BioCyc 53-84-9 CAS C00020 KEGG Compound C00027 KEGG Compound L-Glutamic acid C00026 KEGG Compound C00025 KEGG Compound C00024 KEGG Compound SMILES NCSCCC(S)CCCCC(O)=O 3432-99-3 CAS Glycyl-tRNA 298-12-4 CAS 1118-68-9 CAS Carbon dioxide Q9UL12 UniProt D-3-phosphoglycerate dehydrogenase 52-90-4 CAS 760 PubChem-compound C00037 KEGG Compound Glyoxylic acid 653 ChemSpider C00041 KEGG Compound HMDB0003406 HMDB HMDB0000139 HMDB 1.0 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O Hydroxypyruvic acid 408 ChemSpider CHEBI:18047 ChEBI C00048 KEGG Compound 107-97-1 CAS Orotidylic acid SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O L-serine dehydratase/L-threonine deaminase SMILES N[C@@H](COP(O)(O)=O)C(O)=O SMILES CNCC(O)=O Phosphoserine aminotransferase 604-98-8 CAS HMDB0000148 HMDB 1.0 CHEBI:29162 ChEBI L-Seryl-tRNA(Ser) Glycyl-tRNA L-Seryl-tRNA Glycyl-tRNA(Gly) Reaction816 false L-Cystathionine + Water → 2-Ketobutyric acid + Ammonia + L-Cysteine LEFT_TO_RIGHT 784 PubChem-compound Reaction815 false Homocysteine + L-Serine → L-Cystathionine + Water LEFT_TO_RIGHT C3H7O7P 3-Phosphoglyceric acid 185.99294 HMDB0001487 HMDB GLYOX BioCyc SMILES N[C@@H](CCCNC(N)=N)C(O)=O C00062 KEGG Compound Pyruvic acid 1.0 C5H9NO3 5-Aminolevulinic acid 131.05824 5,10-Methylene-THF CHEBI:29156 ChEBI 5907 ChemSpider C10H16N5O13P3 Adenosine triphosphate 506.99576 C00067 KEGG Compound C00065 KEGG Compound 1.0 NAD 1.0 Pyrophosphate SMILES CC(=O)C(O)=O ReactionCatalysis1513 ACTIVATION ReactionCatalysis1515 ACTIVATION ReactionCatalysis1514 ACTIVATION C00073 KEGG Compound ReactionCatalysis1516 ACTIVATION HMDB0000161 HMDB P50440 UniProt 3-Phosphoglyceric acid SubPathwayOutput 962 PubChem-compound DIMETHYL-GLYCINE BioCyc Serine--pyruvate aminotransferase 31983 ChemSpider 724 PubChem-compound 964 PubChem-compound Dimethylglycine CO2 Carbon dioxide 43.98983 857 ChemSpider HMDB0001024 HMDB SMILES O=O BETAINE BioCyc Glycine dehydrogenase [decarboxylating], mitochondrial HMDB0002111 HMDB HMDB0001022 HMDB SubPathwayInteraction621 SubPathway621Reaction SubPathwayReaction Glycerate kinase 1.0 14265-44-2 CAS SubPathwayInteraction624 SubPathwayReaction SubPathway624Reaction PYRUVATE BioCyc 712 PubChem-compound CHEBI:15811 ChEBI SubPathwayInteraction623 SubPathwayReaction SubPathway623Reaction SubPathwayInteraction629 SubPathway629Reaction SubPathwayReaction C00091 KEGG Compound G3P BioCyc C4H6O3 2-Ketobutyric acid 102.03169 HMDB0000187 HMDB 1.0 C3H7NO2S L-Cysteine 121.01975 644102 PubChem-compound C00097 KEGG Compound 1.0 SMILES OCC(=O)C(O)=O 1.0 H2O2 Hydrogen peroxide 34.005478 6-S-ACETYL-DIHYDROLIPOATE BioCyc Glycine NADH BioCyc HMDB0002134 HMDB CREATINE BioCyc Pyruvaldehyde 1.0 977 PubChem-compound Sarcosine dehydrogenase, mitochondrial 1.0 50-00-0 CAS 1.0 Glycine--tRNA ligase Acetyl-CoA C02291 KEGG Compound 820-11-1 CAS 1.0 30572 ChemSpider SMILES N[C@@H](CS)C(O)=O C05330 KEGG Compound C8H14O2S2 (R)-lipoic acid 206.04352 SMILES OO H3N Ammonia 17.026548 1.0 C10H14N5O7P Adenosine monophosphate 347.06308 C5H11NO2 Betaine 117.07898 4.0 1.0 1.0 HMDB0000538 HMDB 1.0 Phosphoserine phosphatase Ammonia Serines BioCyc 6816 PubChem-compound 1.0 51 PubChem-compound 242 ChemSpider CHEBI:17906 ChEBI C4H9N3O2 Creatine 131.06947 58 PubChem-compound 49791978 PubChem-compound L-Cystathionine C16241 KEGG Compound CH2O Formaldehyde 30.010565 274 ChemSpider P23378 UniProt 137 PubChem-compound 141140 ChemSpider Q14353 UniProt 485-80-3 CAS O4P Phosphate 94.95342 L-2-Amino-3-oxobutanoic acid SER BioCyc 1.0 Serine--tRNA ligase, cytoplasmic SubPathwayInteraction609 SubPathwayReaction SubPathway609Reaction Q9Y617 UniProt Amine oxidase [flavin-containing] A AMINO-ACETONE BioCyc 1.0 CPD-6641 BioCyc L-Seryl-tRNA 217 ChemSpider 58-68-4 CAS HMDB0000574 HMDB 1.0 SMP0000040 SMPDB HMDB0001423 HMDB SMILES [O-]P([O-])([O-])=O 210 ChemSpider (R)-lipoic acid SMILES C=O HMDB0001426 HMDB 692 ChemSpider HMDB0013639 HMDB CHEBI:30915 ChEBI C2H5NO2 Glycine 75.03203 C2H2O3 Glyoxylic acid 74.0004 298-08-8 CAS 2.0 HMDB0001429 HMDB C3H7N3O2 Guanidoacetic acid 117.053825 1.0 GO:0005759 GENE ONTOLOGY C20H23N7O6 5,10-Methylene-THF 457.171 1.0 Gluconeogenesis SubPathway 105 PubChem-compound 586 PubChem-compound O43175 UniProt Oxoglutaric acid SMILES O=C=O Glycine dehydrogenase [decarboxylating], mitochondrial 5950 PubChem-compound 5951 PubChem-compound Homocysteine SMP0000060 SMPDB C21H29N7O14P2 NADH 665.12476 P21397 UniProt Glycine amidinotransferase, mitochondrial HMDB0001206 HMDB 5957 PubChem-compound GO:0005743 GENE ONTOLOGY GO:0005741 GENE ONTOLOGY CHEBI:16842 ChEBI HMDB0000119 HMDB 3-P-HYDROXYPYRUVATE BioCyc HMDB0000123 HMDB GO:0005739 GENE ONTOLOGY 1.0 SMILES CCC(=O)C(O)=O GO:0005737 GENE ONTOLOGY HMDB0000128 HMDB 1.0 C7H14N2O4S L-Cystathionine 222.06743 1.0 C4H9NO2 Dimethylglycine 103.06333 HMDB0001451 HMDB OROTIDINE-5-PHOSPHATE BioCyc CHEBI:16891 ChEBI 389046 ChemSpider 5682 ChemSpider 5,10-Methylene-THF METHYL-GLYOXAL BioCyc false Aminoacetone + Oxygen + Water → Ammonia + Hydrogen peroxide + Pyruvaldehyde LEFT_TO_RIGHT SMP0000004 SMPDB C00719 KEGG Compound Mitochondrial Matrix Formaldehyde 1.0 14000-31-8 CAS L-2-Amino-3-oxobutanoic acid CO-A BioCyc P05091 UniProt Dimethylglycine dehydrogenase, mitochondrial Guanidinoacetate N-methyltransferase 72-89-9 CAS CHEBI:17750 ChEBI HMDB0000939 HMDB Carbon dioxide 1.0 C8H16O2S2 Dihydrolipoate 208.05917 SMP0000013 SMPDB 5,10-Methylene-THF Q8IVS8 UniProt 6557 ChemSpider CHEBI:17724 ChEBI 106-60-5 CAS 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial false Acetyl-CoA + Glycine → Coenzyme A + L-2-Amino-3-oxobutanoic acid LEFT_TO_RIGHT 127-17-3 CAS C3H6O4 Glyceric acid 106.02661 CHEBI:30933 ChEBI 28782 PubChem-compound Hydrogen peroxide false (R)-lipoic acid + Glycine → 8-[(Aminomethyl)sulfanyl]-6-sulfanyloctanoic acid + Carbon dioxide LEFT_TO_RIGHT 312-84-5 CAS Q14749 UniProt 1.0 false Sarcosine + Water → Formaldehyde + Glycine LEFT_TO_RIGHT false Dimethylglycine + Water → Formaldehyde + Sarcosine LEFT_TO_RIGHT C5H9NO4 L-Glutamic acid 147.05316 Water 33032 PubChem-compound CHEBI:16643 ChEBI Dihydrolipoyl dehydrogenase, mitochondrial P34897 UniProt Reaction1429 false L-2-Amino-3-oxobutanoic acid → Aminoacetone + Carbon dioxide LEFT_TO_RIGHT P34896 UniProt Phosphoserine C00740 KEGG Compound 7782-44-7 CAS 1.0 false NAD + Pyruvaldehyde → NADH + Pyruvic acid + Water LEFT_TO_RIGHT SMP0000034 SMPDB NADH 9606 TAXONOMY CHEBI:17549 ChEBI 2-KETOGLUTARATE BioCyc 392413 ChemSpider SMILES OC(COP(O)(O)=O)C(O)=O 388392 ChemSpider L-Methionine C3H4O2 Pyruvaldehyde 72.021126 SMILES NCC(=O)CCC(O)=O L-Seryl-tRNA(Ser) PW000018 PathWhiz false 5,10-Methylene-THF + Glycine + Water ↔ L-Serine + Tetrahydrofolic acid REVERSIBLE CHEBI:15377 ChEBI L-Cysteine SubPathwayInput CHEBI:15379 ChEBI CHEBI:16467 ChEBI 56-45-1 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 Serine hydroxymethyltransferase, cytosolic HMDB0000742 HMDB Dimethylglycine dehydrogenase, mitochondrial AMINO-OXOBUT BioCyc false 8-[(Aminomethyl)sulfanyl]-6-sulfanyloctanoic acid + Tetrahydrofolic acid → 5,10-Methylene-THF + Ammonia + Dihydrolipoate LEFT_TO_RIGHT ReactionCatalysis1498 ACTIVATION L-Alanine 5-aminolevulinate synthase, nonspecific, mitochondrial O75600 UniProt Glycine dehydrogenase [decarboxylating], mitochondrial 3-METHYLBENZYLSUCCINYL-COA BioCyc C00546 KEGG Compound 74-79-3 CAS HMDB0001846 HMDB 1.0 CHEBI:16680 ChEBI HMDB0000517 HMDB CHEBI:15351 ChEBI C00300 KEGG Compound 85-61-0 CAS 1.0 P21549 UniProt 454-29-5 CAS C01888 KEGG Compound 7722-84-1 CAS 6022 PubChem-compound C23H38N7O17P3S Acetyl-CoA 809.1258 939 ChemSpider L-Serine 937 ChemSpider CYS BioCyc CHEBI:16134 ChEBI 1.0 HMDB0003125 HMDB Serine--pyruvate aminotransferase HMDB0000092 HMDB HMDB0001185 HMDB HMDB0000099 HMDB PW000054 PathWhiz CHEBI:17230 ChEBI ATP BioCyc 18714427 ChemSpider Tetrahydrofolic acid Tetrahydrofolic acid 388334 ChemSpider C15H23N6O5S S-Adenosylmethionine 399.14505 1.0 952 ChemSpider Aldehyde dehydrogenase, mitochondrial 107-43-7 CAS Q9UI17 UniProt ARG BioCyc 5858 ChemSpider Adenosine monophosphate C00109 KEGG Compound METHYLENE-THF BioCyc C00581 KEGG Compound 704 ChemSpider Aminoacetone 1.0 C00101 KEGG Compound 1.0 SMILES OC(=O)CCCCC(S)CCS 440033 PubChem-compound PPI BioCyc 160617 PubChem-compound 5-aminolevulinate synthase, nonspecific, mitochondrial FORMALDEHYDE BioCyc 1.0 5886 ChemSpider SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N Cytosol C00597 KEGG Compound C14H20N6O5S S-Adenosylhomocysteine 384.12158 SARCOSINE BioCyc 1.0 1.0 CHEBI:18361 ChEBI NADH CHEBI:18367 ChEBI 1032 ChemSpider 1031 ChemSpider 388320 ChemSpider P13196 UniProt 1.0 SMILES CC(=O)C=O Pyruvic acid SubPathwayInput C21H28N7O14P2 NAD 664.11694 CHEBI:17482 ChEBI Adenosine triphosphate HMDB0000902 HMDB Succinyl-CoA HMDB0006454 HMDB 1.0 388301 ChemSpider 1057 ChemSpider 388307 ChemSpider C00143 KEGG Compound 56-88-2 CAS 5653 ChemSpider Pyruvaldehyde 57689797 PubChem-compound Guanidoacetic acid C5H11NO2S L-Methionine 149.05106 2.0 C3H7NO3 D-Serine 105.042595 C01005 KEGG Compound 880 PubChem-compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 328-50-7 CAS AMP BioCyc GUANIDOACETIC_ACID BioCyc 1.0 HYDROGEN-PEROXIDE BioCyc Glycine amidinotransferase, mitochondrial HMDB0000250 HMDB HMDB0001341 HMDB P49591 UniProt LIPOIC-ACID BioCyc Phosphoserine phosphatase C00168 KEGG Compound 763 ChemSpider SMILES N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O SMILES CN(C)CC(O)=O HMDB0001352 HMDB 1.0 421 PubChem-compound 78-98-8 CAS 7732-18-5 CAS C01026 KEGG Compound Glycine amidinotransferase, mitochondrial NAD 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 SMILES OC(=O)CCCC[C@@H]1CCSS1 SMILES C[N+](C)(C)CC([O-])=O Glycyl-tRNA(Gly) AMMONIA BioCyc SMILES N 56-86-0 CAS 63-68-3 CAS HMDB0000271 HMDB HMDB0000272 HMDB L-Serine NAD 56-40-6 CAS 1.0 Sarcosine HMDB0001377 HMDB S-Adenosylhomocysteine HMDB0000045 HMDB 2.0 1.0 1.0 CHEBI:17050 ChEBI SMILES CN(CC(O)=O)C(N)=N Formaldehyde HMDB0000043 HMDB C3H7NO2 L-Alanine 89.047676 2.0 5800 ChemSpider C3H7NO Aminoacetone 73.052765 D-3-phosphoglycerate dehydrogenase 730 ChemSpider Water HMDB0001149 HMDB Aldehyde dehydrogenase, mitochondrial SMILES OC[C@@H](O)C(O)=O HMDB0000051 HMDB Phosphoserine aminotransferase SMILES N[C@@H](CCC(O)=O)C(O)=O Betaine C4H9NO2S Homocysteine 135.0354 C02147 KEGG Compound 58-64-0 CAS 1.0 C03232 KEGG Compound 1.0 L-serine dehydratase/L-threonine deaminase Q9GZT4 UniProt HOMO-CYS BioCyc 1.0 C3H7NO3 L-Serine 105.042595 HMDB0000064 HMDB Aldehyde dehydrogenase, mitochondrial 444493 PubChem-compound 57-00-1 CAS 6083 PubChem-compound C4H7NO3 L-2-Amino-3-oxobutanoic acid 117.042595 2-PG BioCyc 757 ChemSpider HMDB0001167 HMDB 25246222 PubChem-compound Glycine SMILES OC(=O)C=O ACETYL-COA BioCyc H2O Water 18.010565 Dihydrolipoyl dehydrogenase, mitochondrial SMILES NCC(O)=O NAD BioCyc Guanidinoacetate N-methyltransferase 743 ChemSpider 5-AMINO-LEVULINATE BioCyc Aminomethyltransferase, mitochondrial 740 ChemSpider 3-P-SERINE BioCyc SMILES [H][C@@]12CN(CN1C1=C(NC2)N=C(N)NC1=O)C1=CC=C(C=C1)C(=O)NC(CCC(O)=O)C(O)=O Aminoacetone SMILES NC(=N)NCC(O)=O 247 PubChem-compound 2149-82-8 CAS CHEBI:15842 ChEBI 1.0 Aminomethyltransferase, mitochondrial 5-Aminolevulinic acid SMILES CC(=O)[C@H](N)C(O)=O Sphingolipid Metabolism SubPathway 1.0 134 ChemSpider SMILES O C6H14N4O2 L-Arginine 174.11168 D-Serine 1.0 473-81-4 CAS CHEBI:15611 ChEBI 62-46-4 CAS 64231 ChemSpider Glycolysis SubPathway 2-Ketobutyric acid CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 2.0 Glycine Glycine N-methyltransferase SMILES N[C@H](CO)C(O)=O SMILES CSCC[C@H](N)C(O)=O GO:0005829 GENE ONTOLOGY C19H23N7O6 Tetrahydrofolic acid 445.171 C5H6O5 Oxoglutaric acid 146.02153 CHEBI:16908 ChEBI Ammonia ADENOSYL-HOMO-CYS BioCyc Reaction669 false Betaine + Homocysteine → Dimethylglycine + L-Methionine LEFT_TO_RIGHT Serine hydroxymethyltransferase, cytosolic CHEBI:32398 ChEBI Sarcosine dehydrogenase, mitochondrial Serine hydroxymethyltransferase, mitochondrial 5862 PubChem-compound Serine--pyruvate aminotransferase 1.0 HMDB0001533 HMDB 62074 ChemSpider 600-18-0 CAS Pyruvate Metabolism SubPathway C10H13N2O11P Orotidylic acid 368.0257 Mitochondrion THF BioCyc Phosphohydroxypyruvic acid CHEBI:16919 ChEBI GLY BioCyc CHEBI:16977 ChEBI Guanidoacetic acid HMDB0000208 HMDB ReactionCatalysis1518 ACTIVATION Glyceric acid SMILES NC1=NC(=O)C2=C(NC[C@H](CNC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)N2)N1 ReactionCatalysis1522 ACTIVATION ReactionCatalysis1521 ACTIVATION Water C3H4O4 Hydroxypyruvic acid 104.010956 ReactionCatalysis1524 ACTIVATION ReactionCatalysis1523 ACTIVATION HMDB0000696 HMDB ReactionCatalysis1526 ACTIVATION ReactionCatalysis1525 ACTIVATION SMILES OC(=O)CCC(=O)C(O)=O ReactionCatalysis1528 ACTIVATION ReactionCatalysis1527 ACTIVATION 124-38-9 CAS ReactionCatalysis1520 ACTIVATION CHEBI:15414 ChEBI 6857549 PubChem-compound HMDB0000218 HMDB ReactionCatalysis1529 ACTIVATION 1.0 673 PubChem-compound 566 ChemSpider 1.0 5257127 PubChem-compound 1113-60-6 CAS SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N1C(=O)NC(=O)C=C1C(O)=O 7664-41-7 CAS 1.0 GLT BioCyc L-serine dehydratase/L-threonine deaminase Serine hydroxymethyltransferase, mitochondrial 1.0 Serine racemase Glycine and Serine Metabolism 462-20-4 CAS false Dihydrolipoate + NAD → (R)-lipoic acid + NADH LEFT_TO_RIGHT S-ADENOSYLMETHIONINE BioCyc SMILES C[C@H](N)C(O)=O SMILES CC(=O)CN 222 PubChem-compound HMDB0012210 HMDB 1.0 O7P2 Pyrophosphate 173.91193 OH-PYR BioCyc 6082 ChemSpider Creatine SMILES NC(CCS)C(O)=O Glycine--tRNA ligase Cysteine Metabolism SubPathway 215 PubChem-compound CHEBI:15636 ChEBI HMDB0000243 HMDB SMILES N[C@@H](CO)C(O)=O 1.0 103 ChemSpider P48728 UniProt Adenosine triphosphate 1.0 C10H15N5O10P2 Adenosine diphosphate 427.02942 1.0 HMDB0000005 HMDB 1.0 C3H8NO6P Phosphoserine 185.00893 1.0 C3H7NO2 Sarcosine 89.047676 Mitochondrial Outer Membrane SMP0000128 SMPDB ReactionCatalysis1160 ACTIVATION 1.0 1.0 4.0 8-[(Aminomethyl)sulfanyl]-6-sulfanyloctanoic acid SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc HMDB0000807 HMDB Reaction1770 false Glycine + Pyruvic acid ↔ Glyoxylic acid + L-Alanine REVERSIBLE CHEBI:30831 ChEBI CHEBI:1146900 ChEBI false Glycine + Succinyl-CoA → 5-Aminolevulinic acid + Coenzyme A LEFT_TO_RIGHT false Guanidoacetic acid + S-Adenosylhomocysteine → Creatine + S-Adenosylmethionine LEFT_TO_RIGHT false Glycine + L-Arginine ↔ Guanidoacetic acid + Orotidylic acid REVERSIBLE P78330 UniProt Water Reaction1769 false L-Serine + Pyruvic acid ↔ Hydroxypyruvic acid + L-Alanine REVERSIBLE 1088 PubChem-compound S-Adenosylmethionine C21H36N7O16P3S Coenzyme A 767.11523 Adenosine diphosphate Cytoplasm Serine--tRNA ligase, cytoplasmic ReactionCatalysis1174 ACTIVATION Glycine CHEBI:15422 ChEBI Coenzyme A 1.0 Homo sapiens SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 388299 ChemSpider 1.0 false Adenosine triphosphate + Glycine + Glycyl-tRNA → Adenosine monophosphate + Glycyl-tRNA(Gly) + Pyrophosphate LEFT_TO_RIGHT Reaction1793 false L-Serine → D-Serine LEFT_TO_RIGHT O2 Oxygen 31.98983 false Adenosine triphosphate + L-Serine + L-Seryl-tRNA → Adenosine monophosphate + L-Seryl-tRNA(Ser) + Pyrophosphate LEFT_TO_RIGHT false L-Serine + Tetrahydrofolic acid ↔ 5,10-Methylene-THF + Glycine + Water REVERSIBLE 1.0 CHEBI:40673 ChEBI CHEBI:16523 ChEBI CHEBI:16526 ChEBI 1.0 CHEBI:16761 ChEBI false S-Adenosylhomocysteine + Sarcosine ↔ Glycine + S-Adenosylmethionine REVERSIBLE P20132 UniProt Reaction1789 false L-Serine ↔ Ammonia + Pyruvic acid REVERSIBLE CHEBI:15428 ChEBI false L-Glutamic acid + Phosphohydroxypyruvic acid ↔ Oxoglutaric acid + Phosphoserine REVERSIBLE false Phosphoserine + Water → L-Serine + Phosphate LEFT_TO_RIGHT 1.0 Serine--tRNA ligase, cytoplasmic false 3-Phosphoglyceric acid + NAD ↔ NADH + Phosphohydroxypyruvic acid REVERSIBLE false Adenosine triphosphate + Glyceric acid ↔ 3-Phosphoglyceric acid + Adenosine diphosphate REVERSIBLE PW000148 PathWhiz PW000146 PathWhiz 5893 PubChem-compound 1.0 Dihydrolipoate 1.0 CHEBI:32816 ChEBI L-Serine SubPathwayInput 1.0 1.0 CHEBI:16344 ChEBI 2.0 Sarcosine 1.0 Phosphate 280 PubChem-compound C9H19NO2S2 8-[(Aminomethyl)sulfanyl]-6-sulfanyloctanoic acid 237.08572 L-Serine ReactionCatalysis1135 ACTIVATION 25243997 PubChem-compound SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O ReactionCatalysis1149 ACTIVATION 407-41-0 CAS ReactionCatalysis1146 ACTIVATION 3946848 PubChem-compound 1060 PubChem-compound 1061 PubChem-compound HMDB0001967 HMDB Tetrahydrofolic acid P41250 UniProt 24762165 PubChem-compound CHEBI:30841 ChEBI ReactionCatalysis1151 ACTIVATION 13781857 PubChem-compound ReactionCatalysis1153 ACTIVATION ReactionCatalysis1157 ACTIVATION Amine oxidase [flavin- containing] A Aldehyde dehydrogenase, mitochondrial 2-amino-3- ketobutyrate coenzyme A ligase, mitochondrial Dimethylglycine dehydrogenase, mitochondrial Sarcosine dehydrogenase, mitochondrial Glycine dehydrogenase [decarboxylating], mitochondrial Aminomethyltransferase, mitochondrial Serine hydroxymethyltransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Serine-- pyruvate aminotransferase Serine-- pyruvate aminotransferase Glycine amidinotransferase, mitochondrial Guanidinoacetate N- methyltransferase 5- aminolevulinate synthase, nonspecific, mitochondrial Betaine-- homocysteine S- methyltransferase 1 Glycine N- methyltransferase Glycerate kinase D-3- phosphoglycerate dehydrogenase Phosphoserine aminotransferase Phosphoserine phosphatase L-serine dehydratase/L- threonine deaminase Serine hydroxymethyltransferase, cytosolic Serine racemase Cystathionine beta-synthase Cystathionine gamma-lyase Serine--tRNA ligase, cytoplasmic Glycine--tRNA ligase L-Cysteine 3- Phosphoglyceric acid Pyruvic acid Pyruvic acid Pyruvic acid L-Serine Aminoacetone O 2 H 2 O NH 3 H 2 O 2 Pyruvaldehyde NAD NADH H 2 O L-2-Amino-3- oxobutanoic acid CO 2 Acetyl-CoA Glycine CoA Dimethylglycine H 2 O Formaldehyde Sarcosine H 2 O Formaldehyde (R)-lipoic acid 8-[(Aminomethyl)sulfanyl]-6- sulfanyloctanoic acid CO 2 Dihydrolipoate NH 3 5,10-Methylene-THF Glycine H 2 O Tetrahydrofolic acid L-Serine NAD NADH Hydroxypyruvic acid L-Alanine Glyoxylic acid L-Arginine Guanidoacetic acid Orotidylic acid S-Adenosylhomocysteine S-Adenosylmethionine Creatine Succinyl-CoA 5- Aminolevulinic acid CoA Betaine Homocysteine L-Methionine S-Adenosylhomocysteine S-Adenosylmethionine Glycine Glyceric acid ATP