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CHEBI:16015 ChEBI CHEBI:16136 ChEBI 30572 ChemSpider 6022 PubChem-compound SubPathwayInteraction834 SubPathwayReaction SubPathway834Reaction SMILES N[C@@H](CS)C(O)=O SubPathwayInteraction837 SubPathway837Reaction SubPathwayReaction 937 ChemSpider SubPathwayInteraction838 SubPathwayReaction SubPathway838Reaction SubPathwayInteraction835 SubPathwayReaction SubPathway835Reaction CYS BioCyc 5975 PubChem-compound SubPathwayInteraction836 SubPathway836Reaction SubPathwayReaction tRNA(Cys) CHEBI:16134 ChEBI SubPathwayInteraction839 SubPathwayReaction SubPathway839Reaction C8H14N2O5S gamma-Glutamylcysteine 250.06235 1.0 Methionine Metabolism SubPathway CNS Thiocyanate 57.975143 O60931 UniProt TransportCatalysis97 ACTIVATION 4.4.1.1 false 4.4.1.1 L-Cysteine + Water → Ammonia + Hydrogen sulfide + Pyruvic acid LEFT_TO_RIGHT 18779926 PubChem-compound 439153 PubChem-compound SMILES O L-cysteinyl-tRNA(Cys) H3N Ammonia 17.026548 L-lactate dehydrogenase A chain C10H14N5O7P Adenosine monophosphate 347.06308 50 ChemSpider CHEBI:17359 ChEBI PW000056 PathWhiz CHEBI:16027 ChEBI PW000054 PathWhiz Cysteine--tRNA ligase, cytoplasmic HMDB0000538 HMDB 439270 PubChem-compound 1004 PubChem-compound ATP BioCyc SubPathwayInteraction828 SubPathway828Reaction SubPathwayReaction SubPathwayInteraction829 SubPathway829Reaction SubPathwayReaction Aspartate aminotransferase, cytoplasmic 1.0 Sulfate/Sulfite Metabolism SubPathway 51 PubChem-compound Water SMILES OC(CS)C(O)=O 559142 ChemSpider CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 O3S Sulfite 79.95682 Transport126 false L-Cysteine (→) Transport: Homo sapiens, Cell, Lysosome to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 3-Mercaptolactic acid Lysosome 1.0 SMILES N[C@@H](CS(=O)=O)C(O)=O 141158 ChemSpider 5742 ChemSpider 3-mercaptopyruvate sulfurtransferase CHEBI:17561 ChEBI PW000040 PathWhiz 952 ChemSpider GO:0005829 GENE ONTOLOGY HMDB0001405 HMDB Cystinosin C5H6O5 Oxoglutaric acid 146.02153 391 ChemSpider SMILES OC(=O)C(=O)CS([O-])=O CHEBI:16908 ChEBI 5858 ChemSpider Adenosine monophosphate PW000032 PathWhiz PW000038 PathWhiz PW000157 PathWhiz 5862 PubChem-compound PPI BioCyc Pyruvate Metabolism SubPathway 302-04-5 CAS 6.3.2.2 false 6.3.2.2 Adenosine triphosphate + L-Cysteine + L-Glutamic acid → Adenosine diphosphate + Phosphoric acid + gamma-Glutamylcysteine LEFT_TO_RIGHT HMDB0003276 HMDB 2.8.1.2 false 2.8.1.2 3-Mercaptopyruvic acid + Cyanide → Pyruvic acid + Thiocyanate LEFT_TO_RIGHT Reaction713 true 3-Sulfinylpyruvic acid + Water → Pyruvic acid + Sulfite LEFT_TO_RIGHT Reaction711 false 3-Sulfinoalanine + Oxoglutaric acid → 3-Sulfinylpyruvic acid + L-Glutamic acid LEFT_TO_RIGHT HMDB0000208 HMDB L-Glutamic acid SubPathwayOutput Cytosol CPD-6641 BioCyc 217 ChemSpider ReactionCatalysis55 ACTIVATION HMDB0000574 HMDB 58-68-4 CAS SMILES OC(=O)CCC(=O)C(O)=O 7664-38-2 CAS 1.13.11.20 false 1.13.11.20 L-Cysteine + Oxygen → 3-Sulfinoalanine LEFT_TO_RIGHT CHEBI:30915 ChEBI 1.0 96 ChemSpider GO:0005764 GENE ONTOLOGY HSCN BioCyc SMP0000041 SMPDB C00009 KEGG Compound C00008 KEGG Compound C00007 KEGG Compound Aspartate aminotransferase, cytoplasmic 5755 ChemSpider 3-Sulfinylpyruvic acid 6.1.1.16 false 6.1.1.16 Adenosine triphosphate + L-Cysteine + tRNA(Cys) → Adenosine monophosphate + L-cysteinyl-tRNA(Cys) + Pyrophosphate LEFT_TO_RIGHT Glutamate--cysteine ligase regulatory subunit C00001 KEGG Compound CHEBI:18361 ChEBI C00004 KEGG Compound C00003 KEGG Compound 1.0 C00002 KEGG Compound 1031 ChemSpider P48506 UniProt P48507 UniProt C3H4O3S 3-Mercaptopyruvic acid 119.98811 16743745 ChemSpider 3-SULFINYL-PYRUVATE BioCyc 2.0 Reaction720 false L-Cysteine + Oxoglutaric acid ↔ 3-Mercaptopyruvic acid + L-Glutamic acid REVERSIBLE GLT BioCyc 7664-41-7 CAS 1.1.1.27 false 1.1.1.27 3-Mercaptolactic acid + NAD → 3-Mercaptopyruvic acid + NADH LEFT_TO_RIGHT 7783-06-4 CAS gamma-Glutamylcysteine SubPathwayInput HMDB0002084 HMDB Glycine and Serine Metabolism SubPathway Oxygen Cysteine dioxygenase type 1 1068 ChemSpider C21H28N7O14P2 NAD 664.11694 1.0 Adenosine triphosphate Glutamate--cysteine ligase catalytic subunit 1.0 1.0 C05823 KEGG Compound HMDB0000902 HMDB 222 PubChem-compound C00014 KEGG Compound C00013 KEGG Compound SMILES OP(O)(O)=O O7P2 Pyrophosphate 173.91193 SMP0000060 SMPDB C21H29N7O14P2 NADH 665.12476 3-mercaptopyruvate sulfurtransferase 1.0 5957 PubChem-compound P00338 UniProt Cysteine Metabolism Pyruvic acid SubPathwayInput H2S Hydrogen sulfide 33.98772 C00022 KEGG Compound 56-65-5 CAS L-lactate dehydrogenase A chain 5653 ChemSpider 57517667 PubChem-compound 53-84-9 CAS Cystinosin C00020 KEGG Compound Cystathionine gamma-lyase C00026 KEGG Compound C00025 KEGG Compound CHEBI:26078 ChEBI 1.0 SMP0000072 SMPDB HMDB0000243 HMDB HMDB0001453 HMDB Taurine and Hypotaurine Metabolism SubPathway C10H15N5O10P2 Adenosine diphosphate 427.02942 4.0 Thiocyanate GO:0005737 GENE ONTOLOGY Glutamate--cysteine ligase regulatory subunit CHN Cyanide 27.010899 Aspartate aminotransferase, cytoplasmic Glutamate--cysteine ligase catalytic subunit 1.0 HMDB0000240 HMDB Pantothenate and CoA Biosynthesis SubPathway 1.0 C3H7NO4S 3-Sulfinoalanine 153.00958 1.0 C00957 KEGG Compound 1.0 52-90-4 CAS NADH SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O P49589 UniProt 1.0 1099 PubChem-compound 5682 ChemSpider 328-50-7 CAS C3H3O5S 3-Sulfinylpyruvic acid 150.97012 SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 2614-83-7 CAS AMP BioCyc C00283 KEGG Compound 1.0 110467 ChemSpider SMP0000004 SMPDB tRNA(Cys) HMDB0000250 HMDB L-cysteinyl-tRNA(Cys) 1.0 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O HMDB0001341 HMDB 14000-31-8 CAS C00606 KEGG Compound CHEBI:17514 ChEBI CHEBI:17515 ChEBI Cysteine--tRNA ligase, cytoplasmic Sulfite 160645 PubChem-compound SMILES S SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB0000148 HMDB 1115-65-7 CAS SMILES C#[N-] Cytoplasm 1.0 SMP0000013 SMPDB CHEBI:29167 ChEBI SO3 BioCyc CHEBI:15422 ChEBI SMP0000027 SMPDB Homo sapiens C00177 KEGG Compound 4911362 ChemSpider P32929 UniProt 1.0 SMILES N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O 3-Sulfinoalanine SubPathwayInput 7732-18-5 CAS 388299 ChemSpider SMILES [S-]C#N HMDB0001487 HMDB 61-19-8 CAS 123938 PubChem-compound SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 O2 Oxygen 31.98983 HMDB0001368 HMDB 127-17-3 CAS AMMONIA BioCyc SMILES N 56-86-0 CAS L-Cysteine SubPathwayOutput SubPathwayInput CHEBI:29152 ChEBI Adenosine diphosphate SMP0000021 SMPDB Hydrogen sulfide C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:18022 ChEBI Glutamate--cysteine ligase Phosphoric acid Cystathionine gamma-lyase 8961 ChemSpider CHEBI:16761 ChEBI 7782-44-7 CAS Pyrophosphate HMDB0001377 HMDB SMILES CC(=O)C(O)=O HMDB0000045 HMDB SMILES [O-]S([O-])=O 1.0 Ammonia SMP0000033 SMPDB 9606 TAXONOMY 962 PubChem-compound ReactionCatalysis231 ACTIVATION 2-KETOGLUTARATE BioCyc 5800 ChemSpider 3-SULFINOALANINE BioCyc C05527 KEGG Compound 979 ChemSpider 636-58-8 CAS 1.0 5893 PubChem-compound SMILES O=O H3O4P Phosphoric acid 97.9769 Glutamate Metabolism SubPathway Oxoglutaric acid HMDB0000051 HMDB ReactionCatalysis229 ACTIVATION PW000018 PathWhiz SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0002111 HMDB CHEBI:32816 ChEBI 3-MERCAPTO-PYRUVATE BioCyc ReactionCatalysis228 ACTIVATION ReactionCatalysis226 ACTIVATION 1.0 CHEBI:15377 ChEBI L-Cysteine CHEBI:15379 ChEBI ReactionCatalysis221 ACTIVATION 2464-23-5 CAS ReactionCatalysis220 ACTIVATION PYRUVATE BioCyc 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 Cystathionine gamma-lyase 9322 PubChem-compound 1.0 3-Mercaptopyruvic acid HMDB0002127 HMDB C00094 KEGG Compound P25325 UniProt 98 PubChem-compound ReactionCatalysis219 ACTIVATION Q16878 UniProt C3H7NO2S L-Cysteine 121.01975 644102 PubChem-compound 6083 PubChem-compound 1.0 PW000003 PathWhiz 1.0 C00097 KEGG Compound HS BioCyc HMDB0001049 HMDB HMDB0000996 HMDB H2O Water 18.010565 57-12-5 CAS NADH BioCyc NAD BioCyc C00669 KEGG Compound 1060 PubChem-compound 14265-45-3 CAS CHEBI:41721 ChEBI C01755 KEGG Compound 977 PubChem-compound CHEBI:16208 ChEBI L-GAMMA-GLUTAMYLCYSTEINE BioCyc SMILES OC(=O)C(=O)CS 1.0 Cyanide C3H6O3S 3-Mercaptolactic acid 122.00376 Cysteine dioxygenase type 1 1.0 NAD L-Cysteine P17174 UniProt HMDB0002142 HMDB Cystinosin Aspartate aminotransferase, cytoplasmic 3- mercaptopyruvate sulfurtransferase L-lactate dehydrogenase A-like 6A Cysteine dioxygenase type 1 Cystathionine gamma-lyase Aspartate aminotransferase, cytoplasmic Glutamate-- cysteine ligase Cysteine--tRNA ligase, cytoplasmic L-Glutamic acid gamma- Glutamylcysteine 3- Sulfinoalanine Pyruvic acid L-Cysteine L-Cysteine Oxoglutaric acid 3- Sulfinylpyruvic acid L-Glutamic acid H 2 O Sulfite 3- Mercaptopyruvic acid Cyanide Thiocyanate 3- Mercaptolactic acid NAD NADH O 2 H 2 O Hydrogen sulfide NH 3 Oxoglutaric acid L-Glutamic acid ATP ADP P i ATP AMP PP i Pyridoxal 5'-phosphate Fe2+ Pyridoxal 5'-phosphate Zinc (II) ion tRNA(Cys) L- cysteinyl- tRNA(Cys) Glutamate Metabolism Glutamate Metabolism Taurine and Hypotaurine Metabolism Sulfate/Sulfite Metabolism Pyruvate Metabolism Methionine Metabolism Glycine and Serine Metabolism Pantothenate and CoA Biosynthesis Pyridoxal 5'-phosphate Extracellular Space Intracellular Space Intracellular Space Extracellular Space
CHEBI:16015 ChEBI CHEBI:16136 ChEBI 30572 ChemSpider 6022 PubChem-compound SubPathwayInteraction834 SubPathwayReaction SubPathway834Reaction SMILES N[C@@H](CS)C(O)=O SubPathwayInteraction837 SubPathway837Reaction SubPathwayReaction 937 ChemSpider SubPathwayInteraction838 SubPathwayReaction SubPathway838Reaction SubPathwayInteraction835 SubPathwayReaction SubPathway835Reaction CYS BioCyc 5975 PubChem-compound SubPathwayInteraction836 SubPathway836Reaction SubPathwayReaction tRNA(Cys) CHEBI:16134 ChEBI SubPathwayInteraction839 SubPathwayReaction SubPathway839Reaction C8H14N2O5S gamma-Glutamylcysteine 250.06235 1.0 Methionine Metabolism SubPathway CNS Thiocyanate 57.975143 O60931 UniProt TransportCatalysis97 ACTIVATION 4.4.1.1 false 4.4.1.1 L-Cysteine + Water → Ammonia + Hydrogen sulfide + Pyruvic acid LEFT_TO_RIGHT 18779926 PubChem-compound 439153 PubChem-compound SMILES O L-cysteinyl-tRNA(Cys) H3N Ammonia 17.026548 L-lactate dehydrogenase A chain C10H14N5O7P Adenosine monophosphate 347.06308 50 ChemSpider CHEBI:17359 ChEBI PW000056 PathWhiz CHEBI:16027 ChEBI PW000054 PathWhiz Cysteine--tRNA ligase, cytoplasmic HMDB0000538 HMDB 439270 PubChem-compound 1004 PubChem-compound ATP BioCyc SubPathwayInteraction828 SubPathway828Reaction SubPathwayReaction SubPathwayInteraction829 SubPathway829Reaction SubPathwayReaction Aspartate aminotransferase, cytoplasmic 1.0 Sulfate/Sulfite Metabolism SubPathway 51 PubChem-compound Water SMILES OC(CS)C(O)=O 559142 ChemSpider CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 O3S Sulfite 79.95682 Transport126 false L-Cysteine (→) Transport: Homo sapiens, Cell, Lysosome to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 3-Mercaptolactic acid Lysosome 1.0 SMILES N[C@@H](CS(=O)=O)C(O)=O 141158 ChemSpider 5742 ChemSpider 3-mercaptopyruvate sulfurtransferase CHEBI:17561 ChEBI PW000040 PathWhiz 952 ChemSpider GO:0005829 GENE ONTOLOGY HMDB0001405 HMDB Cystinosin C5H6O5 Oxoglutaric acid 146.02153 391 ChemSpider SMILES OC(=O)C(=O)CS([O-])=O CHEBI:16908 ChEBI 5858 ChemSpider Adenosine monophosphate PW000032 PathWhiz PW000038 PathWhiz PW000157 PathWhiz 5862 PubChem-compound PPI BioCyc Pyruvate Metabolism SubPathway 302-04-5 CAS 6.3.2.2 false 6.3.2.2 Adenosine triphosphate + L-Cysteine + L-Glutamic acid → Adenosine diphosphate + Phosphoric acid + gamma-Glutamylcysteine LEFT_TO_RIGHT HMDB0003276 HMDB 2.8.1.2 false 2.8.1.2 3-Mercaptopyruvic acid + Cyanide → Pyruvic acid + Thiocyanate LEFT_TO_RIGHT Reaction713 true 3-Sulfinylpyruvic acid + Water → Pyruvic acid + Sulfite LEFT_TO_RIGHT Reaction711 false 3-Sulfinoalanine + Oxoglutaric acid → 3-Sulfinylpyruvic acid + L-Glutamic acid LEFT_TO_RIGHT HMDB0000208 HMDB L-Glutamic acid SubPathwayOutput Cytosol CPD-6641 BioCyc 217 ChemSpider ReactionCatalysis55 ACTIVATION HMDB0000574 HMDB 58-68-4 CAS SMILES OC(=O)CCC(=O)C(O)=O 7664-38-2 CAS 1.13.11.20 false 1.13.11.20 L-Cysteine + Oxygen → 3-Sulfinoalanine LEFT_TO_RIGHT CHEBI:30915 ChEBI 1.0 96 ChemSpider GO:0005764 GENE ONTOLOGY HSCN BioCyc SMP0000041 SMPDB C00009 KEGG Compound C00008 KEGG Compound C00007 KEGG Compound Aspartate aminotransferase, cytoplasmic 5755 ChemSpider 3-Sulfinylpyruvic acid 6.1.1.16 false 6.1.1.16 Adenosine triphosphate + L-Cysteine + tRNA(Cys) → Adenosine monophosphate + L-cysteinyl-tRNA(Cys) + Pyrophosphate LEFT_TO_RIGHT Glutamate--cysteine ligase regulatory subunit C00001 KEGG Compound CHEBI:18361 ChEBI C00004 KEGG Compound C00003 KEGG Compound 1.0 C00002 KEGG Compound 1031 ChemSpider P48506 UniProt P48507 UniProt C3H4O3S 3-Mercaptopyruvic acid 119.98811 16743745 ChemSpider 3-SULFINYL-PYRUVATE BioCyc 2.0 Reaction720 false L-Cysteine + Oxoglutaric acid ↔ 3-Mercaptopyruvic acid + L-Glutamic acid REVERSIBLE GLT BioCyc 7664-41-7 CAS 1.1.1.27 false 1.1.1.27 3-Mercaptolactic acid + NAD → 3-Mercaptopyruvic acid + NADH LEFT_TO_RIGHT 7783-06-4 CAS gamma-Glutamylcysteine SubPathwayInput HMDB0002084 HMDB Glycine and Serine Metabolism SubPathway Oxygen Cysteine dioxygenase type 1 1068 ChemSpider C21H28N7O14P2 NAD 664.11694 1.0 Adenosine triphosphate Glutamate--cysteine ligase catalytic subunit 1.0 1.0 C05823 KEGG Compound HMDB0000902 HMDB 222 PubChem-compound C00014 KEGG Compound C00013 KEGG Compound SMILES OP(O)(O)=O O7P2 Pyrophosphate 173.91193 SMP0000060 SMPDB C21H29N7O14P2 NADH 665.12476 3-mercaptopyruvate sulfurtransferase 1.0 5957 PubChem-compound P00338 UniProt Cysteine Metabolism Pyruvic acid SubPathwayInput H2S Hydrogen sulfide 33.98772 C00022 KEGG Compound 56-65-5 CAS L-lactate dehydrogenase A chain 5653 ChemSpider 57517667 PubChem-compound 53-84-9 CAS Cystinosin C00020 KEGG Compound Cystathionine gamma-lyase C00026 KEGG Compound C00025 KEGG Compound CHEBI:26078 ChEBI 1.0 SMP0000072 SMPDB HMDB0000243 HMDB HMDB0001453 HMDB Taurine and Hypotaurine Metabolism SubPathway C10H15N5O10P2 Adenosine diphosphate 427.02942 4.0 Thiocyanate GO:0005737 GENE ONTOLOGY Glutamate--cysteine ligase regulatory subunit CHN Cyanide 27.010899 Aspartate aminotransferase, cytoplasmic Glutamate--cysteine ligase catalytic subunit 1.0 HMDB0000240 HMDB Pantothenate and CoA Biosynthesis SubPathway 1.0 C3H7NO4S 3-Sulfinoalanine 153.00958 1.0 C00957 KEGG Compound 1.0 52-90-4 CAS NADH SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O P49589 UniProt 1.0 1099 PubChem-compound 5682 ChemSpider 328-50-7 CAS C3H3O5S 3-Sulfinylpyruvic acid 150.97012 SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 2614-83-7 CAS AMP BioCyc C00283 KEGG Compound 1.0 110467 ChemSpider SMP0000004 SMPDB tRNA(Cys) HMDB0000250 HMDB L-cysteinyl-tRNA(Cys) 1.0 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O HMDB0001341 HMDB 14000-31-8 CAS C00606 KEGG Compound CHEBI:17514 ChEBI CHEBI:17515 ChEBI Cysteine--tRNA ligase, cytoplasmic Sulfite 160645 PubChem-compound SMILES S SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB0000148 HMDB 1115-65-7 CAS SMILES C#[N-] Cytoplasm 1.0 SMP0000013 SMPDB CHEBI:29167 ChEBI SO3 BioCyc CHEBI:15422 ChEBI SMP0000027 SMPDB Homo sapiens C00177 KEGG Compound 4911362 ChemSpider P32929 UniProt 1.0 SMILES N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O 3-Sulfinoalanine SubPathwayInput 7732-18-5 CAS 388299 ChemSpider SMILES [S-]C#N HMDB0001487 HMDB 61-19-8 CAS 123938 PubChem-compound SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 O2 Oxygen 31.98983 HMDB0001368 HMDB 127-17-3 CAS AMMONIA BioCyc SMILES N 56-86-0 CAS L-Cysteine SubPathwayOutput SubPathwayInput CHEBI:29152 ChEBI Adenosine diphosphate SMP0000021 SMPDB Hydrogen sulfide C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:18022 ChEBI Glutamate--cysteine ligase Phosphoric acid Cystathionine gamma-lyase 8961 ChemSpider CHEBI:16761 ChEBI 7782-44-7 CAS Pyrophosphate HMDB0001377 HMDB SMILES CC(=O)C(O)=O HMDB0000045 HMDB SMILES [O-]S([O-])=O 1.0 Ammonia SMP0000033 SMPDB 9606 TAXONOMY 962 PubChem-compound ReactionCatalysis231 ACTIVATION 2-KETOGLUTARATE BioCyc 5800 ChemSpider 3-SULFINOALANINE BioCyc C05527 KEGG Compound 979 ChemSpider 636-58-8 CAS 1.0 5893 PubChem-compound SMILES O=O H3O4P Phosphoric acid 97.9769 Glutamate Metabolism SubPathway Oxoglutaric acid HMDB0000051 HMDB ReactionCatalysis229 ACTIVATION PW000018 PathWhiz SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0002111 HMDB CHEBI:32816 ChEBI 3-MERCAPTO-PYRUVATE BioCyc ReactionCatalysis228 ACTIVATION ReactionCatalysis226 ACTIVATION 1.0 CHEBI:15377 ChEBI L-Cysteine CHEBI:15379 ChEBI ReactionCatalysis221 ACTIVATION 2464-23-5 CAS ReactionCatalysis220 ACTIVATION PYRUVATE BioCyc 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 Cystathionine gamma-lyase 9322 PubChem-compound 1.0 3-Mercaptopyruvic acid HMDB0002127 HMDB C00094 KEGG Compound P25325 UniProt 98 PubChem-compound ReactionCatalysis219 ACTIVATION Q16878 UniProt C3H7NO2S L-Cysteine 121.01975 644102 PubChem-compound 6083 PubChem-compound 1.0 PW000003 PathWhiz 1.0 C00097 KEGG Compound HS BioCyc HMDB0001049 HMDB HMDB0000996 HMDB H2O Water 18.010565 57-12-5 CAS NADH BioCyc NAD BioCyc C00669 KEGG Compound 1060 PubChem-compound 14265-45-3 CAS CHEBI:41721 ChEBI C01755 KEGG Compound 977 PubChem-compound CHEBI:16208 ChEBI L-GAMMA-GLUTAMYLCYSTEINE BioCyc SMILES OC(=O)C(=O)CS 1.0 Cyanide C3H6O3S 3-Mercaptolactic acid 122.00376 Cysteine dioxygenase type 1 1.0 NAD L-Cysteine P17174 UniProt HMDB0002142 HMDB CTNS GOT1 MPST LDHAL6A CDO1 CTH GOT1 GCLC GCLM CARS L-Glutamic acid gamma- Glutamylcysteine 3- Sulfinoalanine Pyruvic acid L-Cysteine L-Cysteine Oxoglutaric acid 3- Sulfinylpyruvic acid L-Glutamic acid Water Sulfite 3- Mercaptopyruvic acid Cyanide Thiocyanate 3- Mercaptolactic acid NAD NADH Oxygen Water Hydrogen sulfide Ammonia Oxoglutaric acid L-Glutamic acid Adenosine triphosphate Adenosine diphosphate Phosphoric acid Adenosine triphosphate Adenosine monophosphate Pyrophosphate tRNA(Cys) L- cysteinyl- tRNA(Cys) Glutamate Metabolism Glutamate Metabolism Taurine and Hypotaurine Metabolism Sulfate/Sulfite Metabolism Pyruvate Metabolism Methionine Metabolism Glycine and Serine Metabolism Pantothenate and CoA Biosynthesis