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7722-84-1 CAS D-amino-acid oxidase 937 ChemSpider C00792 KEGG Compound 1.0 CHEBI:16134 ChEBI Peroxisome HMDB0003125 HMDB C6H14N4O2 D-Arginine 174.11168 64224 ChemSpider HYDROGEN-PEROXIDE BioCyc SMILES O C5H9NO3 5-Amino-2-oxopentanoic acid 131.05824 SMILES OO H3N Ammonia 17.026548 57-13-6 CAS 388519 ChemSpider HMDB0006875 HMDB D-Arginine and D-Ornithine Metabolism 71070 PubChem-compound 1.0 1.0 P14920 UniProt 64236 ChemSpider 389057 ChemSpider Oxygen 763 ChemSpider HMDB0004225 HMDB HMDB0003416 HMDB C5H7NO2 1-Pyrroline-2-carboxylic acid 113.047676 CH4N2O Urea 60.032364 HMDB0003374 HMDB CPD-824 BioCyc 1.0 784 PubChem-compound Homo sapiens 7732-18-5 CAS 1143 ChemSpider C03564 KEGG Compound CHEBI:16199 ChEBI CHEBI:36761 ChEBI 952 ChemSpider SMILES N[C@H](CCCNC(N)=N)C(O)=O O2 Oxygen 31.98983 SMILES NCCCC(=O)C(O)=O 440046 PubChem-compound D-amino-acid oxidase D-Ornithine SubPathwayOutput AMMONIA BioCyc SMILES N UREA BioCyc SubPathwayInteraction68 SubPathwayReaction SubPathway68Reaction CHEBI:15816 ChEBI 1.0 5-AMINO-2-OXOPENTANOATE BioCyc 1.4.3.3 false 1.4.3.3 D-Ornithine + Oxygen + Water → 5-Amino-2-oxopentanoic acid + Ammonia + Hydrogen peroxide LEFT_TO_RIGHT C5H12N2O2 D-Ornithine 132.08987 CHEBI:16240 ChEBI 7782-44-7 CAS CHEBI:58489 ChEBI HMDB0001377 HMDB SMILES [O-]C(=O)C1=[NH+]CCC1 542 ChemSpider SMILES NC(N)=O SMP0000036 SMPDB GO:0005777 GENE ONTOLOGY 71082 PubChem-compound 9606 TAXONOMY C00515 KEGG Compound CPD-217 BioCyc 962 PubChem-compound ReactionCatalysis232 ACTIVATION HMDB0006272 HMDB ReactionCatalysis233 ACTIVATION Water 348-66-3 CAS 2.0 CPD-6641 BioCyc DELTA1-PYRROLINE_2-CARBOXYLATE BioCyc CHEBI:16176 ChEBI 217 ChemSpider 1.0 1176 PubChem-compound Ammonia 2139-03-9 CAS SMILES O=O PW000019 PathWhiz HMDB0000051 HMDB D-amino-acid oxidase HMDB0002111 HMDB CHEBI:49268 ChEBI D-Arginine SubPathwayOutput C6H11N3O3 2-Oxoarginine 173.08005 HMDB0000294 HMDB 2-Oxoarginine CHEBI:15377 ChEBI C00007 KEGG Compound CHEBI:15379 ChEBI Reaction724 true 5-Amino-2-oxopentanoic acid + Urea ↔ 2-Oxoarginine + Water REVERSIBLE Reaction725 true 5-Amino-2-oxopentanoic acid ↔ 1-Pyrroline-2-carboxylic acid + Water REVERSIBLE 1.4.3.3 false 1.4.3.3 D-Arginine + Oxygen + Water → 2-Oxoarginine + Ammonia + Hydrogen peroxide LEFT_TO_RIGHT 558 PubChem-compound C00001 KEGG Compound CPD-220 BioCyc Intestinal Microflora SubPathway SMILES NCCC[C@@H](N)C(O)=O C00086 KEGG Compound 1-Pyrroline-2-carboxylic acid Urea 7664-41-7 CAS 5-Amino-2-oxopentanoic acid Hydrogen peroxide 157-06-2 CAS 1.0 1.0 222 PubChem-compound C00014 KEGG Compound 1.0 H2O Water 18.010565 H2O2 Hydrogen peroxide 34.005478 SMILES NC(N)=NCCCC(=O)C(O)=O 3715-10-4 CAS 977 PubChem-compound C01110 KEGG Compound C00027 KEGG Compound C03771 KEGG Compound 439402 PubChem-compound 1.0 D-amino-acid oxidase D-amino-acid oxidase D-Arginine D-Ornithine H 2 O O 2 5-Amino-2-oxopentanoic acid NH 3 H 2 O 2 2-Oxoarginine Urea H 2 O 1-Pyrroline- 2-carboxylic acid H 2 O FAD FAD Extracellular Space Intracellular Space Peroxisome Peroxisome
7722-84-1 CAS D-amino-acid oxidase 937 ChemSpider C00792 KEGG Compound 1.0 CHEBI:16134 ChEBI Peroxisome HMDB0003125 HMDB C6H14N4O2 D-Arginine 174.11168 64224 ChemSpider HYDROGEN-PEROXIDE BioCyc SMILES O C5H9NO3 5-Amino-2-oxopentanoic acid 131.05824 SMILES OO H3N Ammonia 17.026548 57-13-6 CAS 388519 ChemSpider HMDB0006875 HMDB D-Arginine and D-Ornithine Metabolism 71070 PubChem-compound 1.0 1.0 P14920 UniProt 64236 ChemSpider 389057 ChemSpider Oxygen 763 ChemSpider HMDB0004225 HMDB HMDB0003416 HMDB C5H7NO2 1-Pyrroline-2-carboxylic acid 113.047676 CH4N2O Urea 60.032364 HMDB0003374 HMDB CPD-824 BioCyc 1.0 784 PubChem-compound Homo sapiens 7732-18-5 CAS 1143 ChemSpider C03564 KEGG Compound CHEBI:16199 ChEBI CHEBI:36761 ChEBI 952 ChemSpider SMILES N[C@H](CCCNC(N)=N)C(O)=O O2 Oxygen 31.98983 SMILES NCCCC(=O)C(O)=O 440046 PubChem-compound D-amino-acid oxidase D-Ornithine SubPathwayOutput AMMONIA BioCyc SMILES N UREA BioCyc SubPathwayInteraction68 SubPathwayReaction SubPathway68Reaction CHEBI:15816 ChEBI 1.0 5-AMINO-2-OXOPENTANOATE BioCyc 1.4.3.3 false 1.4.3.3 D-Ornithine + Oxygen + Water → 5-Amino-2-oxopentanoic acid + Ammonia + Hydrogen peroxide LEFT_TO_RIGHT C5H12N2O2 D-Ornithine 132.08987 CHEBI:16240 ChEBI 7782-44-7 CAS CHEBI:58489 ChEBI HMDB0001377 HMDB SMILES [O-]C(=O)C1=[NH+]CCC1 542 ChemSpider SMILES NC(N)=O SMP0000036 SMPDB GO:0005777 GENE ONTOLOGY 71082 PubChem-compound 9606 TAXONOMY C00515 KEGG Compound CPD-217 BioCyc 962 PubChem-compound ReactionCatalysis232 ACTIVATION HMDB0006272 HMDB ReactionCatalysis233 ACTIVATION Water 348-66-3 CAS 2.0 CPD-6641 BioCyc DELTA1-PYRROLINE_2-CARBOXYLATE BioCyc CHEBI:16176 ChEBI 217 ChemSpider 1.0 1176 PubChem-compound Ammonia 2139-03-9 CAS SMILES O=O PW000019 PathWhiz HMDB0000051 HMDB D-amino-acid oxidase HMDB0002111 HMDB CHEBI:49268 ChEBI D-Arginine SubPathwayOutput C6H11N3O3 2-Oxoarginine 173.08005 HMDB0000294 HMDB 2-Oxoarginine CHEBI:15377 ChEBI C00007 KEGG Compound CHEBI:15379 ChEBI Reaction724 true 5-Amino-2-oxopentanoic acid + Urea ↔ 2-Oxoarginine + Water REVERSIBLE Reaction725 true 5-Amino-2-oxopentanoic acid ↔ 1-Pyrroline-2-carboxylic acid + Water REVERSIBLE 1.4.3.3 false 1.4.3.3 D-Arginine + Oxygen + Water → 2-Oxoarginine + Ammonia + Hydrogen peroxide LEFT_TO_RIGHT 558 PubChem-compound C00001 KEGG Compound CPD-220 BioCyc Intestinal Microflora SubPathway SMILES NCCC[C@@H](N)C(O)=O C00086 KEGG Compound 1-Pyrroline-2-carboxylic acid Urea 7664-41-7 CAS 5-Amino-2-oxopentanoic acid Hydrogen peroxide 157-06-2 CAS 1.0 1.0 222 PubChem-compound C00014 KEGG Compound 1.0 H2O Water 18.010565 H2O2 Hydrogen peroxide 34.005478 SMILES NC(N)=NCCCC(=O)C(O)=O 3715-10-4 CAS 977 PubChem-compound C01110 KEGG Compound C00027 KEGG Compound C03771 KEGG Compound 439402 PubChem-compound 1.0 Peroxisome DAO DAO D-Arginine D-Ornithine Water Oxygen 5-Amino-2- oxopentanoic acid Ammonia Hydrogen peroxide 2-Oxoarginine Urea Water 1-Pyrroline- 2-carboxylic acid Water Intestinal Microflora