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Pathway Description
Fructose and Mannose Degradation
Homo sapiens
Metabolic Pathway
Created: 2013-08-01
Last Updated: 2023-10-25
Fructose and mannose are monosaccharides that can be found in many foods. Fructose can join with glucose to form sucrose. Mannose can be converted to glucose. Both may be used as food sweeteners. Fructose is well absorbed, especially in the presence of glucose. Fructose causes less of an insulin response compared to glucose and thus may be a preferred sugar for diabetics. In contrast to fructose, humans do not metabolize mannose well with the majority of it being excreted unchanged. Mannose in the urine can be beneficial in treating urinary tract infections caused be E. coli. However, mannose can be detrimental to humans by causing diabetic complications.
References
Fructose and Mannose Degradation References
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Pubmed: 8387495
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