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S-Adenosylmethionine 17215925 ChemSpider Q9NZJ6 UniProt Ubiquinone biosynthesis monooxygenase COQ6 937 ChemSpider 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 1.0 2-Hexaprenyl-6-methoxy-1,4-benzoquinone 132 ChemSpider SMILES O HMDB0001063 HMDB HMDB0001185 HMDB Ubiquinone 6 4-Hydroxybenzoic acid 1.0 1.0 Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial C37H54O4 3-Hexaprenyl-4,5-Dihydroxybenzoic acid 562.4022 559142 ChemSpider 1.0 Ubiquinone biosynthesis monooxygenase COQ6 4444377 ChemSpider C39H58O4 Ubiquinone 6 590.43353 C15H23N6O5S S-Adenosylmethionine 399.14505 3-Hexaprenyl-4,5-Dihydroxybenzoic acid 53-59-8 CAS 4444374 ChemSpider 4444375 ChemSpider HMDB0036062 HMDB 4444376 ChemSpider 66551-60-8 CAS Ubiquinone biosynthesis protein COQ7 homolog 1038 PubChem-compound 1.0 CHEBI:16474 ChEBI 952 ChemSpider 1065-31-2 CAS SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\COP(O)(=O)OP(O)(O)=O 5280828 PubChem-compound Hydrogen Ion 5280826 PubChem-compound 5280827 PubChem-compound 5280825 PubChem-compound C17568 KEGG Compound Q9Y2Z9 UniProt 135 PubChem-compound PW000039 PathWhiz ADENOSYL-HOMO-CYS BioCyc Q5HYK3 UniProt 485-80-3 CAS 1.0 1010 ChemSpider Ubiquinone Biosynthesis CHEBI:30763 ChEBI PPI BioCyc C21H30N7O17P3 NADPH 745.0911 Mitochondrion C21H29N7O17P3 NADP 744.08325 C7H6O3 4-Hydroxybenzoic acid 138.0317 NADPH BioCyc C05804 KEGG Compound C05803 KEGG Compound 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone SMILES COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O C05805 KEGG Compound SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N 979-92-0 CAS C05802 KEGG Compound CPD-6641 BioCyc 1.0 C14H20N6O5S S-Adenosylhomocysteine 384.12158 CHEBI:27752 ChEBI Water Ubiquinone biosynthesis protein COQ7 homolog HMDB0000217 HMDB C13425 KEGG Compound Reaction849 true 3-Hexaprenyl-4-hydroxybenzoic acid → 3-Hexaprenyl-4,5-Dihydroxybenzoic acid LEFT_TO_RIGHT C00007 KEGG Compound 2.5.1.39 false 2.5.1.39 4-Hydroxybenzoic acid + All-trans-hexaprenyl diphosphate → 3-Hexaprenyl-4-hydroxybenzoic acid + Pyrophosphate LEFT_TO_RIGHT C00006 KEGG Compound CHEBI:15414 ChEBI 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial CHEBI:18009 ChEBI C00001 KEGG Compound 3-HEXAPRENYL-45-DIHYDROXYBENZOATE BioCyc CHEBI:18361 ChEBI C00005 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 2-Hexaprenyl-6-methoxyphenol 1.0 HMDB0000221 HMDB 1.0 SMILES OC(=O)C1=CC=C(O)C=C1 CHEBI:28711 ChEBI SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 1.0 53-57-6 CAS ReactionCatalysis411 ACTIVATION C00019 KEGG Compound ALL-TRANS-HEXAPRENYL-DIPHOSPHATE BioCyc CHEBI:16835 ChEBI S-ADENOSYLMETHIONINE BioCyc Oxygen C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 NAD(P) BioCyc Reaction852 false 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + S-Adenosylmethionine → S-Adenosylhomocysteine + Ubiquinone 6 LEFT_TO_RIGHT Reaction850 true 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid → 2-Hexaprenyl-6-methoxyphenol LEFT_TO_RIGHT Reaction851 false 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone + Hydrogen Ion + NADPH + Oxygen → 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + NADP + Water LEFT_TO_RIGHT SMP0000065 SMPDB 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone H Hydrogen Ion 1.007825 388301 ChemSpider C00021 KEGG Compound C01230 KEGG Compound GO:0005739 GENE ONTOLOGY 1.0 Q96H96 UniProt Q99807 UniProt 4-hydroxybenzoate polyprenyltransferase, mitochondrial 65848-03-5 CAS C00156 KEGG Compound 1.0 C30H52O7P2 All-trans-hexaprenyl diphosphate 586.31885 5280760 PubChem-compound S-Adenosylhomocysteine HMDB0000250 HMDB SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS 1.0 5675 ChemSpider HMDB0000939 HMDB CHEBI:31116 ChEBI ReactionCatalysis416 ACTIVATION ReactionCatalysis414 ACTIVATION ReactionCatalysis415 ACTIVATION ReactionCatalysis412 ACTIVATION ReactionCatalysis413 ACTIVATION C38H56O4 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 576.41785 11954011 PubChem-compound Homo sapiens C37H54O3 3-Hexaprenyl-4-hydroxybenzoic acid 546.4073 7732-18-5 CAS C37H56O2 2-Hexaprenyl-6-methoxyphenol 532.42804 All-trans-hexaprenyl diphosphate C37H54O3 2-Hexaprenyl-6-methoxy-1,4-benzoquinone 546.4073 C38H56O3 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone 560.423 HMDB0006816 HMDB O2 Oxygen 31.98983 HMDB0006817 HMDB 3-Hexaprenyl-4-hydroxybenzoic acid 4-hydroxybenzoate polyprenyltransferase, mitochondrial CHEBI:1109 ChEBI 4444089 ChemSpider SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(O)C(O)=CC(=C1)C(O)=O C38H56O4 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid 576.41785 99-96-7 CAS HMDB0006818 HMDB HMDB0006819 HMDB 7782-44-7 CAS 5280413 PubChem-compound 5280776 PubChem-compound HMDB0001377 HMDB 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid 63975-40-6 CAS HMDB0006820 HMDB 9606 TAXONOMY 2-HEXAPRENYL-6-METHOXY-14-BENZOQUINOL BioCyc 962 PubChem-compound 31983 ChemSpider 4446657 ChemSpider SMILES COC1=CC=CC(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C1O SMILES COC1=CC(=O)C=C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)C1=O SMILES COC1=CC(=O)C(C)=C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)C1=O SMILES COC1=C(O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C(=O)C1=O SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=CC(=CC=C1O)C(O)=O C00080 KEGG Compound SMILES O=O 10128306 ChemSpider 98470 PubChem-compound HMDB0002111 HMDB 1.0 CHEBI:15377 ChEBI Pyrophosphate 1.0 CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] 2.1.1.201 false 2.1.1.201 2-Hexaprenyl-6-methoxy-1,4-benzoquinone + S-Adenosylmethionine → 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone + S-Adenosylhomocysteine LEFT_TO_RIGHT 1.14.13.- false 1.14.13.- 2-Hexaprenyl-6-methoxyphenol + Oxygen → 2-Hexaprenyl-6-methoxy-1,4-benzoquinone + Water LEFT_TO_RIGHT HMDB0000977 HMDB SMILES COC1=CC(=CC(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C1O)C(O)=O 5886 PubChem-compound NADP HMDB0000500 HMDB CHEBI:18081 ChEBI Reaction204 false 3-Hexaprenyl-4,5-Dihydroxybenzoic acid + S-Adenosylmethionine → 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid + S-Adenosylhomocysteine LEFT_TO_RIGHT 644102 PubChem-compound CHEBI:17528 ChEBI 4444330 ChemSpider Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O 25246222 PubChem-compound 22833512 PubChem-compound H2O Water 18.010565 1.0 4444339 ChemSpider 977 PubChem-compound NADPH HMDB0059597 HMDB CHEBI:16680 ChEBI HMDB0012188 HMDB C05313 KEGG Compound 24762165 PubChem-compound CHEBI:52971 ChEBI C05200 KEGG Compound 1.0 4- hydroxybenzoate polyprenyltransferase, mitochondrial Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial Ubiquinone biosynthesis monooxygenase COQ6 2-methoxy-6- polyprenyl- 1,4- benzoquinol methylase, mitochondrial Ubiquinone biosynthesis protein COQ7 homolog Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial 4- Hydroxybenzoic acid All-trans-hexaprenyl diphosphate 3-Hexaprenyl-4-hydroxybenzoic acid PP i 3-Hexaprenyl-4,5-Dihydroxybenzoic acid S-Adenosylmethionine S-Adenosylhomocysteine 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid 2-Hexaprenyl-6-methoxyphenol O 2 2-Hexaprenyl-6-methoxy-1,4-benzoquinone H 2 O S-Adenosylmethionine 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone S-Adenosylhomocysteine O 2 NADPH H + 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy- 1,4-benzoquinone NADP H 2 O S-Adenosylmethionine Ubiquinone 6 S-Adenosylhomocysteine Fe3+ Cytosol Mitochondrion Mitochondrial Membrane
S-Adenosylmethionine 17215925 ChemSpider Q9NZJ6 UniProt Ubiquinone biosynthesis monooxygenase COQ6 937 ChemSpider 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 1.0 2-Hexaprenyl-6-methoxy-1,4-benzoquinone 132 ChemSpider SMILES O HMDB0001063 HMDB HMDB0001185 HMDB Ubiquinone 6 4-Hydroxybenzoic acid 1.0 1.0 Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial C37H54O4 3-Hexaprenyl-4,5-Dihydroxybenzoic acid 562.4022 559142 ChemSpider 1.0 Ubiquinone biosynthesis monooxygenase COQ6 4444377 ChemSpider C39H58O4 Ubiquinone 6 590.43353 C15H23N6O5S S-Adenosylmethionine 399.14505 3-Hexaprenyl-4,5-Dihydroxybenzoic acid 53-59-8 CAS 4444374 ChemSpider 4444375 ChemSpider HMDB0036062 HMDB 4444376 ChemSpider 66551-60-8 CAS Ubiquinone biosynthesis protein COQ7 homolog 1038 PubChem-compound 1.0 CHEBI:16474 ChEBI 952 ChemSpider 1065-31-2 CAS SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\COP(O)(=O)OP(O)(O)=O 5280828 PubChem-compound Hydrogen Ion 5280826 PubChem-compound 5280827 PubChem-compound 5280825 PubChem-compound C17568 KEGG Compound Q9Y2Z9 UniProt 135 PubChem-compound PW000039 PathWhiz ADENOSYL-HOMO-CYS BioCyc Q5HYK3 UniProt 485-80-3 CAS 1.0 1010 ChemSpider Ubiquinone Biosynthesis CHEBI:30763 ChEBI PPI BioCyc C21H30N7O17P3 NADPH 745.0911 Mitochondrion C21H29N7O17P3 NADP 744.08325 C7H6O3 4-Hydroxybenzoic acid 138.0317 NADPH BioCyc C05804 KEGG Compound C05803 KEGG Compound 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone SMILES COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O C05805 KEGG Compound SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N 979-92-0 CAS C05802 KEGG Compound CPD-6641 BioCyc 1.0 C14H20N6O5S S-Adenosylhomocysteine 384.12158 CHEBI:27752 ChEBI Water Ubiquinone biosynthesis protein COQ7 homolog HMDB0000217 HMDB C13425 KEGG Compound Reaction849 true 3-Hexaprenyl-4-hydroxybenzoic acid → 3-Hexaprenyl-4,5-Dihydroxybenzoic acid LEFT_TO_RIGHT C00007 KEGG Compound 2.5.1.39 false 2.5.1.39 4-Hydroxybenzoic acid + All-trans-hexaprenyl diphosphate → 3-Hexaprenyl-4-hydroxybenzoic acid + Pyrophosphate LEFT_TO_RIGHT C00006 KEGG Compound CHEBI:15414 ChEBI 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial CHEBI:18009 ChEBI C00001 KEGG Compound 3-HEXAPRENYL-45-DIHYDROXYBENZOATE BioCyc CHEBI:18361 ChEBI C00005 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 2-Hexaprenyl-6-methoxyphenol 1.0 HMDB0000221 HMDB 1.0 SMILES OC(=O)C1=CC=C(O)C=C1 CHEBI:28711 ChEBI SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 1.0 53-57-6 CAS ReactionCatalysis411 ACTIVATION C00019 KEGG Compound ALL-TRANS-HEXAPRENYL-DIPHOSPHATE BioCyc CHEBI:16835 ChEBI S-ADENOSYLMETHIONINE BioCyc Oxygen C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 NAD(P) BioCyc Reaction852 false 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + S-Adenosylmethionine → S-Adenosylhomocysteine + Ubiquinone 6 LEFT_TO_RIGHT Reaction850 true 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid → 2-Hexaprenyl-6-methoxyphenol LEFT_TO_RIGHT Reaction851 false 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone + Hydrogen Ion + NADPH + Oxygen → 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + NADP + Water LEFT_TO_RIGHT SMP0000065 SMPDB 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone H Hydrogen Ion 1.007825 388301 ChemSpider C00021 KEGG Compound C01230 KEGG Compound GO:0005739 GENE ONTOLOGY 1.0 Q96H96 UniProt Q99807 UniProt 4-hydroxybenzoate polyprenyltransferase, mitochondrial 65848-03-5 CAS C00156 KEGG Compound 1.0 C30H52O7P2 All-trans-hexaprenyl diphosphate 586.31885 5280760 PubChem-compound S-Adenosylhomocysteine HMDB0000250 HMDB SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS 1.0 5675 ChemSpider HMDB0000939 HMDB CHEBI:31116 ChEBI ReactionCatalysis416 ACTIVATION ReactionCatalysis414 ACTIVATION ReactionCatalysis415 ACTIVATION ReactionCatalysis412 ACTIVATION ReactionCatalysis413 ACTIVATION C38H56O4 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 576.41785 11954011 PubChem-compound Homo sapiens C37H54O3 3-Hexaprenyl-4-hydroxybenzoic acid 546.4073 7732-18-5 CAS C37H56O2 2-Hexaprenyl-6-methoxyphenol 532.42804 All-trans-hexaprenyl diphosphate C37H54O3 2-Hexaprenyl-6-methoxy-1,4-benzoquinone 546.4073 C38H56O3 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone 560.423 HMDB0006816 HMDB O2 Oxygen 31.98983 HMDB0006817 HMDB 3-Hexaprenyl-4-hydroxybenzoic acid 4-hydroxybenzoate polyprenyltransferase, mitochondrial CHEBI:1109 ChEBI 4444089 ChemSpider SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(O)C(O)=CC(=C1)C(O)=O C38H56O4 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid 576.41785 99-96-7 CAS HMDB0006818 HMDB HMDB0006819 HMDB 7782-44-7 CAS 5280413 PubChem-compound 5280776 PubChem-compound HMDB0001377 HMDB 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid 63975-40-6 CAS HMDB0006820 HMDB 9606 TAXONOMY 2-HEXAPRENYL-6-METHOXY-14-BENZOQUINOL BioCyc 962 PubChem-compound 31983 ChemSpider 4446657 ChemSpider SMILES COC1=CC=CC(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C1O SMILES COC1=CC(=O)C=C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)C1=O SMILES COC1=CC(=O)C(C)=C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)C1=O SMILES COC1=C(O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C(=O)C1=O SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=CC(=CC=C1O)C(O)=O C00080 KEGG Compound SMILES O=O 10128306 ChemSpider 98470 PubChem-compound HMDB0002111 HMDB 1.0 CHEBI:15377 ChEBI Pyrophosphate 1.0 CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] 2.1.1.201 false 2.1.1.201 2-Hexaprenyl-6-methoxy-1,4-benzoquinone + S-Adenosylmethionine → 2-Hexaprenyl-3-methyl-6-methoxy-1,4 benzoquinone + S-Adenosylhomocysteine LEFT_TO_RIGHT 1.14.13.- false 1.14.13.- 2-Hexaprenyl-6-methoxyphenol + Oxygen → 2-Hexaprenyl-6-methoxy-1,4-benzoquinone + Water LEFT_TO_RIGHT HMDB0000977 HMDB SMILES COC1=CC(=CC(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C1O)C(O)=O 5886 PubChem-compound NADP HMDB0000500 HMDB CHEBI:18081 ChEBI Reaction204 false 3-Hexaprenyl-4,5-Dihydroxybenzoic acid + S-Adenosylmethionine → 3-Hexaprenyl-4-hydroxy-5-methoxybenzoic acid + S-Adenosylhomocysteine LEFT_TO_RIGHT 644102 PubChem-compound CHEBI:17528 ChEBI 4444330 ChemSpider Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O 25246222 PubChem-compound 22833512 PubChem-compound H2O Water 18.010565 1.0 4444339 ChemSpider 977 PubChem-compound NADPH HMDB0059597 HMDB CHEBI:16680 ChEBI HMDB0012188 HMDB C05313 KEGG Compound 24762165 PubChem-compound CHEBI:52971 ChEBI C05200 KEGG Compound 1.0 Mitochondria COQ2 COQ3 COQ6 COQ5 COQ7 COQ3 4- Hydroxybenzoic acid All-trans- hexaprenyl diphosphate 3-Hexaprenyl- 4- hydroxybenzoic acid Pyrophosphate 3-Hexaprenyl- 4,5- Dihydroxybenzoic acid S- Adenosylmethionine S- Adenosylhomocysteine 3-Hexaprenyl- 4-hydroxy-5- methoxybenzoic acid 2-Hexaprenyl- 6- methoxyphenol Oxygen 2-Hexaprenyl- 6-methoxy- 1,4- benzoquinone Water S- Adenosylmethionine 2-Hexaprenyl- 3-methyl-6- methoxy-1,4 benzoquinone S- Adenosylhomocysteine Oxygen NADPH Hydrogen Ion 2-Hexaprenyl- 3-methyl-5- hydroxy-6- methoxy-1,4- benzoquinone NADP Water S- Adenosylmethionine Ubiquinone 6 S- Adenosylhomocysteine