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Mineralocorticoid receptor Amiloride- sensitive sodium channel subunit alpha Amiloride- sensitive sodium channel subunit beta Amiloride- sensitive sodium channel subunit delta Amiloride- sensitive sodium channel subunit gamma Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Solute carrier family 12 member 3 Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Chloride channel protein ClC-Ka Solute carrier family 12 member 1 Chloride channel protein ClC-Ka Solute carrier family 22 member 6 Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Solute carrier family 12 member 6 Solute carrier family 22 member 2 Amiloride- sensitive sodium channel subunit alpha Amiloride- sensitive sodium channel subunit beta Amiloride- sensitive sodium channel subunit delta Amiloride- sensitive sodium channel subunit gamma Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Excitatory amino acid transporter 3 Large neutral amino acids transporter small subunit 1 4F2 cell-surface antigen heavy chain Sodium- and chloride- dependent transporter XTRP3 Sodium-coupled neutral amino acid transporter 4 Y+L amino acid transporter 1 4F2 cell-surface antigen heavy chain Y+L amino acid transporter 2 4F2 cell-surface antigen heavy chain Neutral and basic amino acid transport protein rBAT B(0,+)-type amino acid transporter 1 Urea transporter 2 Large neutral amino acids transporter small subunit 2 4F2 cell-surface antigen heavy chain Aquaporin-1 ATP-sensitive inward rectifier potassium channel 1 ATP-sensitive inward rectifier potassium channel 1 Aquaporin-1 Aquaporin-2 Aquaporin-3 Mineralocorticoid receptor Spironolactone Aldosterone Cl- Cl- Na+ Na+ Na+ K+ K+ Cl- Cl- Na+ Na+ K+ K+ Cl- Cl- Cl- Cl- Na+ K+ K+ Cl- Cl- K+ K+ Na+ Na+ Na+ Na+ K+ K+ Na+ Na+ Na+ Na+ Cl- Cl- Na+ Na+ Na+ Na+ Na+ Na+ Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate L-Cysteine L-Cysteine Urea Urea H2O H2O K+ K+ K+ K+ H2O H2O H2O H2O Aldosterone Organic Anion Organic Anion Organic Cation Organic Cation L-Amino acid L-Amino acid Large Neutral Amino Acids Large Neutral Amino Acids Imino acids Imino acids L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid Large Neutral Amino Acids Large Neutral Amino Acids Transcription/Translation Late Distal Convoluted Tubule/Collecting Tubule PROXIMAL CONVOLUTED TUBULE LUMEN INTERSTITIUM DISTAL CONVOLUTED TUBULE LUMEN INTERSTITIUM DESCENDING LIMB OF LOOP OF HENLE LUMEN INTERSTITIUM THICK ASCENDING LIMB OF LOOP OF HENLE LUMEN LUMEN INTERSTITIUM COLLECTING TUBULE INTERSTITIUM Nucleus
NR3C2 SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 SLC12A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 CLCNKA SLC12A1 CLCNKA SLC22A6 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 SLC12A6 SLC22A2 SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 SLC1A1 SLC7A5 SLC3A2 SLC6A20 SLC38A4 SLC7A7 SLC3A2 SLC7A6 SLC3A2 SLC3A1 SLC7A9 SLC14A2 SLC7A8 SLC3A2 AQP1 KCNJ1 KCNJ1 AQP1 AQP2 AQP3 NR3C2 Spironolactone Aldosterone Chloride ion Chloride ion Sodium Sodium Sodium Potassium Potassium Chloride ion Chloride ion Sodium Sodium Potassium Potassium Chloride ion Chloride ion Chloride ion Chloride ion Sodium Potassium Potassium Chloride ion Chloride ion Potassium Potassium Sodium Sodium Sodium Sodium Potassium Potassium Sodium Sodium Sodium Sodium Chloride ion Chloride ion Sodium Sodium Sodium Sodium Sodium Sodium Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate L-Cysteine L-Cysteine Urea Urea Water Water Potassium Potassium Potassium Potassium Water Water Water Water Aldosterone Organic Anion Organic Anion Organic Cation Organic Cation L-Amino acid L-Amino acid Large Neutral Amino Acids Large Neutral Amino Acids Imino acids Imino acids L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid Large Neutral Amino Acids Large Neutral Amino Acids Transcription/Translation Created with Snap
NR3C2 SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 SLC12A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 CLCNKA SLC12A1 CLCNKA SLC22A6 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 SLC12A6 SLC22A2 SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 SLC1A1 SLC7A5 SLC3A2 SLC6A20 SLC38A4 SLC7A7 SLC3A2 SLC7A6 SLC3A2 SLC3A1 SLC7A9 SLC14A2 SLC7A8 SLC3A2 AQP1 KCNJ1 KCNJ1 AQP1 AQP2 AQP3 NR3C2 Sptone Aldostr Cl- Cl- Na+ Na+ Na+ K+ K+ Cl- Cl- Na+ Na+ K+ K+ Cl- Cl- Cl- Cl- Na+ K+ K+ Cl- Cl- K+ K+ Na+ Na+ Na+ Na+ K+ K+ Na+ Na+ Na+ Na+ Cl- Cl- Na+ Na+ Na+ Na+ Na+ Na+ HCO3 HCO3 HCO3 HCO3 Cys Cys Urea Urea H2O H2O K+ K+ K+ K+ H2O H2O H2O H2O Aldostr OA OA OC OC LAA LAA LNAA LNAA IA IA LAA LAA LAA LAA LAA LAA LNAA LNAA PW000455 Late Distal Convoluted Tubule/Collecting Tubule PROXIMAL CONVOLUTED TUBULE LUMEN INTERSTITIUM DISTAL CONVOLUTED TUBULE LUMEN INTERSTITIUM DESCENDING LIMB OF LOOP OF HENLE LUMEN INTERSTITIUM THICK ASCENDING LIMB OF LOOP OF HENLE LUMEN LUMEN INTERSTITIUM COLLECTING TUBULE INTERSTITIUM Nucleus
NR3C2 SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 SLC12A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 CLCNKA SLC12A1 CLCNKA SLC22A6 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 SLC12A6 SLC22A2 SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 SLC1A1 SLC7A5 SLC3A2 SLC6A20 SLC38A4 SLC7A7 SLC3A2 SLC7A6 SLC3A2 SLC3A1 SLC7A9 SLC14A2 SLC7A8 SLC3A2 AQP1 KCNJ1 KCNJ1 AQP1 AQP2 AQP3 NR3C2 Sptone Aldostr Cl Cl Na+ Na+ Na+ K+ K+ Cl Cl Na+ Na+ K+ K+ Cl Cl Cl Cl Na+ K+ K+ Cl Cl K+ K+ Na+ Na+ Na+ Na+ K+ K+ Na+ Na+ Na+ Na+ Cl Cl Na+ Na+ Na+ Na+ Na+ Na+ HCO3 HCO3 HCO3 HCO3 Cys Cys Urea Urea H2O H2O K+ K+ K+ K+ H2O H2O H2O H2O Aldostr OA OA OC OC LAA LAA LNAA LNAA IA IA LAA LAA LAA LAA LAA LAA LNAA LNAA PW000455 Created with Snap