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17215925 ChemSpider 6022 PubChem-compound C4H4O5 Oxalacetic acid 132.00587 C23H38N7O17P3S Acetyl-CoA 809.1258 Malate dehydrogenase, cytoplasmic Mitochondrial pyruvate carrier 1 937 ChemSpider 1.0 CHEBI:30797 ChEBI 439153 PubChem-compound SMILES O CIT BioCyc 1.0 HMDB0000094 HMDB Acetyl-CoA SubPathwayInput 58838673 PubChem-compound TransportCatalysis132 ACTIVATION P11498 UniProt HMDB0000538 HMDB OXALACETIC_ACID BioCyc 1.0 ATP BioCyc TransportCatalysis6 ACTIVATION D-Glucose 4.0 1.0 328-42-7 CAS 6816 PubChem-compound SMILES O[C@@H](CC(O)=O)C(O)=O SMILES OC([O-])=O CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 Reaction1367 false D-Glucose → Pyruvic acid LEFT_TO_RIGHT 1.2.4.1 false 1.2.4.1 Pyruvic acid → Acetyl-CoA LEFT_TO_RIGHT PW000167 PathWhiz 53-59-8 CAS HCO3 BioCyc 5742 ChemSpider 1038 PubChem-compound CHEBI:16474 ChEBI GO:0005829 GENE ONTOLOGY 2280-44-6 CAS ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc 1.0 274 ChemSpider Citric acid 97-67-6 CAS CHEBI:16908 ChEBI PW000154 PathWhiz Pyruvate dehydrogenase E1 component subunit beta, mitochondrial O4P Phosphate 94.95342 945 ChemSpider 77-92-9 CAS 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS 1.0 Adenosine triphosphate CHEBI:30769 ChEBI 1.0 C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 Mitochondrion P40925 UniProt 1.0 NADPH BioCyc 1.0 1.0 1.0 ReactionCatalysis1082 ACTIVATION Carbon dioxide Mitochondrial citrate transport protein Cytosol Q02978 UniProt L-Malic acid 58-68-4 CAS HMDB0001423 HMDB 4.0 Transport72 false Citric acid (←) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Cell, Mitochondrial Matrix LEFT_TO_RIGHT SMILES [O-]P([O-])([O-])=O Reaction390 false L-Malic acid + NAD ↔ Hydrogen Ion + NADH + Oxalacetic acid REVERSIBLE HMDB0000217 HMDB 124-38-9 CAS 1.0 C6H12O6 D-Glucose 180.06339 C00009 KEGG Compound C00008 KEGG Compound C00006 KEGG Compound 1.0 ReactionCatalysis4 ACTIVATION CHEBI:18009 ChEBI HMDB0001429 HMDB GLC BioCyc C00001 KEGG Compound 1.0 C00005 KEGG Compound C00004 KEGG Compound Pyruvic acid CHEBI:18367 ChEBI NADPH 1.0 C00003 KEGG Compound 1032 ChemSpider 1031 ChemSpider C00002 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Mitochondrial 2-oxoglutarate/malate carrier protein HMDB0000221 HMDB HMDB0000223 HMDB SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O GO:0005759 GENE ONTOLOGY Coenzyme A Hydrogen 1.0 Phosphate H2 Hydrogen 2.01565 53-57-6 CAS Pyruvate carboxylase, mitochondrial Pyruvic acid Coenzyme A Malate dehydrogenase, cytoplasmic C21H28N7O14P2 NAD 664.11694 Transport173 false L-Malic acid (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Cell, Mitochondrion LEFT_TO_RIGHT NADP-dependent malic enzyme C00011 KEGG Compound SMILES O=C=O C00010 KEGG Compound 1.0 HMDB0000902 HMDB Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial ReactionCatalysis79 ACTIVATION 1.0 HMDB0000595 HMDB NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound HMDB0001206 HMDB Pyruvate dehydrogenase E1 component subunit beta, mitochondrial H Hydrogen Ion 1.007825 1.0 C00149 KEGG Compound ATP-citrate synthase 1.0 C00022 KEGG Compound 56-65-5 CAS Pyruvate carboxylase, mitochondrial 53-84-9 CAS P48163 UniProt C00024 KEGG Compound Q6LAP8 UniProt HMDB0000243 HMDB HMDB0000122 HMDB Adenosine triphosphate GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 1.0 GO:0005737 GENE ONTOLOGY NADP C6H8O7 Citric acid 192.02701 769 PubChem-compound NADH SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc 19782904 PubChem-compound C00031 KEGG Compound C00158 KEGG Compound CHEBI:18276 ChEBI C00036 KEGG Compound Transport1 false Pyruvic acid (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Cell, Mitochondrial Matrix LEFT_TO_RIGHT 5682 ChemSpider SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Reaction590 false Acetyl-CoA + Oxalacetic acid + Water → Citric acid + Coenzyme A LEFT_TO_RIGHT Oxalacetic acid C00282 KEGG Compound Oxalacetic acid Adenosine diphosphate Malate dehydrogenase, cytoplasmic Mitochondrial Matrix HMDB0001341 HMDB CO-A BioCyc 222656 PubChem-compound 5675 ChemSpider 72-89-9 CAS Pyruvate carboxylase, mitochondrial C00288 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 762 ChemSpider C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O Mitochondrial 2-oxoglutarate/malate carrier protein Adenosine diphosphate Cytoplasm 1.0 ReactionCatalysis1054 ACTIVATION 2.0 ReactionCatalysis1056 ACTIVATION L-Malic acid 4.0 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial CHEBI:15422 ChEBI 5589 ChemSpider 6557 ChemSpider Homo sapiens Hydrogen carbonate SMILES OC(=O)CC(=O)C(O)=O SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Oxalacetic acid 388299 ChemSpider 7732-18-5 CAS 1.0 TransportCatalysis36 ACTIVATION HMDB0000156 HMDB HMDB0001487 HMDB Hydrogen Ion 127-17-3 CAS Pyruvic acid 1.0 HMDB0001362 HMDB ReactionCatalysis1067 ACTIVATION Fatty Acid Biosynthesis SubPathway SubPathwayInteraction210 SubPathway210Reaction SubPathwayReaction P53396 UniProt NAD C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:16526 ChEBI Pyruvate dehydrogenase E1 305 ChemSpider CHEBI:16761 ChEBI 1.0 SMILES CC(=O)C(O)=O Mitochondrial pyruvate carrier 1 6.4.1.1 false 6.4.1.1 Adenosine triphosphate + Hydrogen carbonate + Pyruvic acid → Adenosine diphosphate + Oxalacetic acid + Phosphate LEFT_TO_RIGHT ATP-citrate synthase Transfer of Acetyl Groups into Mitochondria 9606 TAXONOMY 962 PubChem-compound 1333-74-0 CAS NADP-dependent malic enzyme P08559 UniProt CHEBI:17544 ChEBI 5800 ChemSpider 392413 ChemSpider CO2 Carbon dioxide 43.98983 5893 PubChem-compound C00080 KEGG Compound Water 1.1.1.40 false 1.1.1.40 L-Malic acid + NADP → Carbon dioxide + Hydrogen + NADPH + Pyruvic acid LEFT_TO_RIGHT Q9Y5U8 UniProt CHEBI:32816 ChEBI HMDB0002111 HMDB 2.0 CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS PYRUVATE BioCyc SMP0000456 SMPDB 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound L-Malic acid 280 PubChem-compound CHEBI:4167 ChEBI CHEBI:30744 ChEBI P11177 UniProt Oxalacetic acid 5793 PubChem-compound 444493 PubChem-compound 1.0 1.0 1.0 SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O 22833512 PubChem-compound 2.3.3.8 false 2.3.3.8 Adenosine triphosphate + Citric acid + Coenzyme A → Acetyl-CoA + Adenosine diphosphate + Oxalacetic acid LEFT_TO_RIGHT 1.0 ACETYL-COA BioCyc Citric acid H2O Water 18.010565 SMP0000466 SMPDB 193317 ChemSpider NADH BioCyc NAD BioCyc 1060 PubChem-compound 1061 PubChem-compound HMDB0059597 HMDB 1.0 HMDB0001967 HMDB 1.0 Mitochondrial citrate transport protein 1.0 749 ChemSpider 71-52-3 CAS CHEBI:15351 ChEBI 970 PubChem-compound Reaction1341 false Hydrogen + NADPH + Oxalacetic acid → L-Malic acid + NAD LEFT_TO_RIGHT ATP-citrate synthase Acetyl-CoA NADP-dependent malic enzyme C4H6O5 L-Malic acid 134.02153 85-61-0 CAS NAD CHO3 Hydrogen carbonate 60.99257 SMILES [H][H] Mitochondrial citrate transport protein Mitochondrial 2- oxoglutarate/malate carrier protein Mitochondrial pyruvate carrier 1 NADP-dependent malic enzyme Malate dehydrogenase, cytoplasmic ATP-citrate synthase Citrate synthase, mitochondrial Pyruvate dehydrogenase E1 Malate dehydrogenase, cytoplasmic Pyruvate carboxylase, mitochondrial Acetyl-CoA Citric acid Citric acid L-Malic acid Pyruvic acid Pyruvic acid NADP NADPH H + CO 2 Oxalacetic acid H + NADPH NAD CoA ATP ADP Oxalacetic acid Acetyl-CoA H 2 O CoA Pyruvic acid L-Malic acid NAD NADH H + D-Glucose ATP CO 2 ADP P i Manganese Thiamine pyrophosphate Biotin Manganese Fatty Acid Biosynthesis Mitochondrion Cytosol Outer Mitochondrial Membrane Inner Mitochondrial Membrane Mitochondrial Matrix Intracellular Space
17215925 ChemSpider 6022 PubChem-compound C4H4O5 Oxalacetic acid 132.00587 C23H38N7O17P3S Acetyl-CoA 809.1258 Malate dehydrogenase, cytoplasmic Mitochondrial pyruvate carrier 1 937 ChemSpider 1.0 CHEBI:30797 ChEBI 439153 PubChem-compound SMILES O CIT BioCyc 1.0 HMDB0000094 HMDB Acetyl-CoA SubPathwayInput 58838673 PubChem-compound TransportCatalysis132 ACTIVATION P11498 UniProt HMDB0000538 HMDB OXALACETIC_ACID BioCyc 1.0 ATP BioCyc TransportCatalysis6 ACTIVATION D-Glucose 4.0 1.0 328-42-7 CAS 6816 PubChem-compound SMILES O[C@@H](CC(O)=O)C(O)=O SMILES OC([O-])=O CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 Reaction1367 false D-Glucose → Pyruvic acid LEFT_TO_RIGHT 1.2.4.1 false 1.2.4.1 Pyruvic acid → Acetyl-CoA LEFT_TO_RIGHT PW000167 PathWhiz 53-59-8 CAS HCO3 BioCyc 5742 ChemSpider 1038 PubChem-compound CHEBI:16474 ChEBI GO:0005829 GENE ONTOLOGY 2280-44-6 CAS ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc 1.0 274 ChemSpider Citric acid 97-67-6 CAS CHEBI:16908 ChEBI PW000154 PathWhiz Pyruvate dehydrogenase E1 component subunit beta, mitochondrial O4P Phosphate 94.95342 945 ChemSpider 77-92-9 CAS 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS 1.0 Adenosine triphosphate CHEBI:30769 ChEBI 1.0 C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 Mitochondrion P40925 UniProt 1.0 NADPH BioCyc 1.0 1.0 1.0 ReactionCatalysis1082 ACTIVATION Carbon dioxide Mitochondrial citrate transport protein Cytosol Q02978 UniProt L-Malic acid 58-68-4 CAS HMDB0001423 HMDB 4.0 Transport72 false Citric acid (←) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Cell, Mitochondrial Matrix LEFT_TO_RIGHT SMILES [O-]P([O-])([O-])=O Reaction390 false L-Malic acid + NAD ↔ Hydrogen Ion + NADH + Oxalacetic acid REVERSIBLE HMDB0000217 HMDB 124-38-9 CAS 1.0 C6H12O6 D-Glucose 180.06339 C00009 KEGG Compound C00008 KEGG Compound C00006 KEGG Compound 1.0 ReactionCatalysis4 ACTIVATION CHEBI:18009 ChEBI HMDB0001429 HMDB GLC BioCyc C00001 KEGG Compound 1.0 C00005 KEGG Compound C00004 KEGG Compound Pyruvic acid CHEBI:18367 ChEBI NADPH 1.0 C00003 KEGG Compound 1032 ChemSpider 1031 ChemSpider C00002 KEGG Compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Mitochondrial 2-oxoglutarate/malate carrier protein HMDB0000221 HMDB HMDB0000223 HMDB SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O GO:0005759 GENE ONTOLOGY Coenzyme A Hydrogen 1.0 Phosphate H2 Hydrogen 2.01565 53-57-6 CAS Pyruvate carboxylase, mitochondrial Pyruvic acid Coenzyme A Malate dehydrogenase, cytoplasmic C21H28N7O14P2 NAD 664.11694 Transport173 false L-Malic acid (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Cell, Mitochondrion LEFT_TO_RIGHT NADP-dependent malic enzyme C00011 KEGG Compound SMILES O=C=O C00010 KEGG Compound 1.0 HMDB0000902 HMDB Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial ReactionCatalysis79 ACTIVATION 1.0 HMDB0000595 HMDB NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound HMDB0001206 HMDB Pyruvate dehydrogenase E1 component subunit beta, mitochondrial H Hydrogen Ion 1.007825 1.0 C00149 KEGG Compound ATP-citrate synthase 1.0 C00022 KEGG Compound 56-65-5 CAS Pyruvate carboxylase, mitochondrial 53-84-9 CAS P48163 UniProt C00024 KEGG Compound Q6LAP8 UniProt HMDB0000243 HMDB HMDB0000122 HMDB Adenosine triphosphate GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 1.0 GO:0005737 GENE ONTOLOGY NADP C6H8O7 Citric acid 192.02701 769 PubChem-compound NADH SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc 19782904 PubChem-compound C00031 KEGG Compound C00158 KEGG Compound CHEBI:18276 ChEBI C00036 KEGG Compound Transport1 false Pyruvic acid (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Cell, Mitochondrial Matrix LEFT_TO_RIGHT 5682 ChemSpider SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Reaction590 false Acetyl-CoA + Oxalacetic acid + Water → Citric acid + Coenzyme A LEFT_TO_RIGHT Oxalacetic acid C00282 KEGG Compound Oxalacetic acid Adenosine diphosphate Malate dehydrogenase, cytoplasmic Mitochondrial Matrix HMDB0001341 HMDB CO-A BioCyc 222656 PubChem-compound 5675 ChemSpider 72-89-9 CAS Pyruvate carboxylase, mitochondrial C00288 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 762 ChemSpider C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O Mitochondrial 2-oxoglutarate/malate carrier protein Adenosine diphosphate Cytoplasm 1.0 ReactionCatalysis1054 ACTIVATION 2.0 ReactionCatalysis1056 ACTIVATION L-Malic acid 4.0 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial CHEBI:15422 ChEBI 5589 ChemSpider 6557 ChemSpider Homo sapiens Hydrogen carbonate SMILES OC(=O)CC(=O)C(O)=O SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Oxalacetic acid 388299 ChemSpider 7732-18-5 CAS 1.0 TransportCatalysis36 ACTIVATION HMDB0000156 HMDB HMDB0001487 HMDB Hydrogen Ion 127-17-3 CAS Pyruvic acid 1.0 HMDB0001362 HMDB ReactionCatalysis1067 ACTIVATION Fatty Acid Biosynthesis SubPathway SubPathwayInteraction210 SubPathway210Reaction SubPathwayReaction P53396 UniProt NAD C10H16N5O13P3 Adenosine triphosphate 506.99576 CHEBI:16526 ChEBI Pyruvate dehydrogenase E1 305 ChemSpider CHEBI:16761 ChEBI 1.0 SMILES CC(=O)C(O)=O Mitochondrial pyruvate carrier 1 6.4.1.1 false 6.4.1.1 Adenosine triphosphate + Hydrogen carbonate + Pyruvic acid → Adenosine diphosphate + Oxalacetic acid + Phosphate LEFT_TO_RIGHT ATP-citrate synthase Transfer of Acetyl Groups into Mitochondria 9606 TAXONOMY 962 PubChem-compound 1333-74-0 CAS NADP-dependent malic enzyme P08559 UniProt CHEBI:17544 ChEBI 5800 ChemSpider 392413 ChemSpider CO2 Carbon dioxide 43.98983 5893 PubChem-compound C00080 KEGG Compound Water 1.1.1.40 false 1.1.1.40 L-Malic acid + NADP → Carbon dioxide + Hydrogen + NADPH + Pyruvic acid LEFT_TO_RIGHT Q9Y5U8 UniProt CHEBI:32816 ChEBI HMDB0002111 HMDB 2.0 CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS PYRUVATE BioCyc SMP0000456 SMPDB 58-64-0 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound L-Malic acid 280 PubChem-compound CHEBI:4167 ChEBI CHEBI:30744 ChEBI P11177 UniProt Oxalacetic acid 5793 PubChem-compound 444493 PubChem-compound 1.0 1.0 1.0 SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O 22833512 PubChem-compound 2.3.3.8 false 2.3.3.8 Adenosine triphosphate + Citric acid + Coenzyme A → Acetyl-CoA + Adenosine diphosphate + Oxalacetic acid LEFT_TO_RIGHT 1.0 ACETYL-COA BioCyc Citric acid H2O Water 18.010565 SMP0000466 SMPDB 193317 ChemSpider NADH BioCyc NAD BioCyc 1060 PubChem-compound 1061 PubChem-compound HMDB0059597 HMDB 1.0 HMDB0001967 HMDB 1.0 Mitochondrial citrate transport protein 1.0 749 ChemSpider 71-52-3 CAS CHEBI:15351 ChEBI 970 PubChem-compound Reaction1341 false Hydrogen + NADPH + Oxalacetic acid → L-Malic acid + NAD LEFT_TO_RIGHT ATP-citrate synthase Acetyl-CoA NADP-dependent malic enzyme C4H6O5 L-Malic acid 134.02153 85-61-0 CAS NAD CHO3 Hydrogen carbonate 60.99257 SMILES [H][H] Mitochondria Unknown SLC25A11 MPC1 ME1 MDH1 ACLY CS PDHA1 PDHB MDH1 PC Acetyl-CoA Citric acid Citric acid L-Malic acid Pyruvic acid Pyruvic acid NADP NADPH Hydrogen Carbon dioxide Oxalacetic acid Hydrogen NADPH NAD Coenzyme A Adenosine triphosphate Adenosine diphosphate Oxalacetic acid Acetyl-CoA Water Coenzyme A Pyruvic acid L-Malic acid NAD NADH Hydrogen Ion D-Glucose Adenosine triphosphate Hydrogen carbonate Adenosine diphosphate Phosphate Fatty Acid Biosynthesis