Quantitative metabolomics services for biomarker discovery and validation.
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Inosine-5'- monophosphate dehydrogenase 1 Inosine-5'- monophosphate dehydrogenase 2 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 Canalicular multispecific organic anion transporter 1 Canalicular multispecific organic anion transporter 1 Multidrug resistance protein 1 ATP-binding cassette sub-family G member 2 Canalicular multispecific organic anion transporter 1 Cocaine esterase Liver carboxylesterase 1 Cocaine esterase UDP- glucuronosyltransferase 2B7 UDP- glucuronosyltransferase 1-8 UDP- glucuronosyltransferase 1-9 Liver carboxylesterase 1 Cocaine esterase UDP- glucuronosyltransferase 2B7 UDP- glucuronosyltransferase 1-7 UDP- glucuronosyltransferase 1-9 Cocaine esterase Cytochrome P450 3A4 Cytochrome P450 3A5 Cytochrome P450 2C8 Mycophenolic acid Mycophenolic acid Mycophenolate mofetil Mycophenolate mofetil Mycophenolic acid Mycophenolic acid glucuronide Mycophenolic acid O-acyl-glucuronide N-(2-Carboxymethyl)-morpholine N-(2-Hydroxyethyl)-morpholine N-(2-Hydroxyethyl)-morpholine N-oxide N-(2-Carboxymethyl)-morpholine N-(2-Hydroxyethyl)-morpholine N-(2-Hydroxyethyl)-morpholine N-oxide Uridine diphosphate glucuronic acid Mycophenolic acid O-acyl-glucuronide Uridine 5'-diphosphate Uridine diphosphate glucuronic acid Mycophenolic acid glucuronide Uridine 5'-diphosphate H 2 O N-(2-Hydroxyethyl)-morpholine Uridine diphosphate glucuronic acid Mycophenolic acid O-acyl-glucuronide Uridine 5'-diphosphate Uridine diphosphate glucuronic acid Mycophenolic acid glucuronide Uridine 5'-diphosphate H 2 O N-(2-Hydroxyethyl)-morpholine O 2 NADH 6-O-Desmethyl-mycophenolic acid Formaldehyde NAD H 2 O H 2 O ATP P i ADP H 2 O ATP P i ADP H 2 O ATP P i ADP H 2 O ATP P i ADP H 2 O ATP P i ADP Mycophenolic acid Potassium Potassium Heme Heme Heme Bacterial Deconjugation
Endoplasmic Reticulum Endoplasmic Reticulum IMPDH1 IMPDH2 SLCO1B1 SLCO1B3 ABCC2 ABCC2 ABCB1 ABCG2 ABCC2 CES2 CES1 CES2 UGT2B7 UGT1A8 UGT1A9 CES1 CES2 UGT2B7 UGT1A7 UGT1A9 CES2 CYP3A4 CYP3A5 CYP2C8 Mycophenolic acid Mycophenolic acid Mycophenolate mofetil Mycophenolate mofetil Mycophenolic acid Mycophenolic acid glucuronide Mycophenolic acid O-acyl- glucuronide N-(2- Carboxymethyl)- morpholine N-(2- Hydroxyethyl)- morpholine N-(2- Hydroxyethyl)- morpholine N-oxide N-(2- Carboxymethyl)- morpholine N-(2- Hydroxyethyl)- morpholine N-(2- Hydroxyethyl)- morpholine N-oxide Uridine diphosphate glucuronic acid Mycophenolic acid O-acyl- glucuronide Uridine 5'-diphosphate Uridine diphosphate glucuronic acid Mycophenolic acid glucuronide Uridine 5'-diphosphate Water N-(2- Hydroxyethyl)- morpholine Uridine diphosphate glucuronic acid Mycophenolic acid O-acyl- glucuronide Uridine 5'-diphosphate Uridine diphosphate glucuronic acid Mycophenolic acid glucuronide Uridine 5'-diphosphate Water N-(2- Hydroxyethyl)- morpholine Oxygen NADH 6-O- Desmethyl- mycophenolic acid Formaldehyde NAD Water Water Adenosine triphosphate Phosphate Adenosine diphosphate Water Adenosine triphosphate Phosphate Adenosine diphosphate Water Adenosine triphosphate Phosphate Adenosine diphosphate Water Adenosine triphosphate Phosphate Adenosine diphosphate Water Adenosine triphosphate Phosphate Adenosine diphosphate Mycophenolic acid