Nevirapine (also named as Viramune or BIRG587) is a medication that are used for the treatment of HIV/AIDS (especially HIV-1). Nevirapine binds and inhibits reverse transcriptase to create interruption on catalytic site of enzyme so that it can prevent the activities of RNA-dependent and DNA-dependent DNA polymerase, which lead to no complementary DNA (cDNA) produced.
References
Nevirapine Pathway References
Pollard RB, Robinson P, Dransfield K: Safety profile of nevirapine, a nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus infection. Clin Ther. 1998 Nov-Dec;20(6):1071-92.
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