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Guanosine diphosphate 1.0 65914-84-3 CAS Q14643 UniProt DIACYLGLYCEROL BioCyc Inositol 1,4,5-trisphosphate receptor type 1 Endoplasmic Reticulum G protein-coupled receptor C00035 KEGG Compound C01245 KEGG Compound direct_interaction Calcium Reaction2349 false Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine diphosphate + Guanosine triphosphate → Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine triphosphate + Guanosine diphosphate LEFT_TO_RIGHT 1.0 1.0 HMDB0007170 HMDB C00044 KEGG Compound C00165 KEGG Compound Guanine nucleotide-binding protein G(q) subunit alpha SMILES O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O Cytoplasm PW000726 PathWhiz Homo sapiens 1.0 CHEBI:16595 ChEBI Q9NQ66 UniProt 439456 PubChem-compound 85166-31-0 CAS GO:0005783 GENE ONTOLOGY TransportCatalysis230 ACTIVATION Protein kinase C alpha type 53480324 PubChem-compound C00626 KEGG Compound Inositol 1,4,5-trisphosphate receptor type 1 Guanine nucleotide-binding protein G(q) subunit alpha 8977 PubChem-compound Guanine nucleotide-binding protein G(q) (Homo sapiens)_Guanosine diphosphate 6830 PubChem-compound C10H15N5O11P2 Guanosine diphosphate 443.02432 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 HMDB0001498 HMDB 1.0 266 ChemSpider Reaction2350 false PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) → DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) + Inositol 1,4,5-trisphosphate LEFT_TO_RIGHT P17252 UniProt 9606 TAXONOMY Guanosine diphosphate C10H16N5O14P3 Guanosine triphosphate 522.99066 Activation of PKC Through G Protein-Coupled Receptor Guanine nucleotide-binding protein G(q) (Homo sapiens)_Guanosine diphosphate C00076 KEGG Compound 8630 ChemSpider HMDB0010133 HMDB Guanine nucleotide-binding protein G(q) (Homo sapiens)_Guanosine triphosphate CA%2b2 BioCyc C41H72O5 DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) 644.53796 4943054 ChemSpider GO:0005886 GENE ONTOLOGY Ca Calcium 39.96259 inositol_1,4,5-trisphosphate BioCyc C47H85O19P3 PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) 1046.4897 Cell Membrane Phosphatidylinositols BioCyc 6569 ChemSpider Transport283 false Calcium (→) Transport: Homo sapiens, Cell, Endoplasmic Reticulum to Homo sapiens, Cell, Cytoplasm LEFT_TO_RIGHT 271 PubChem-compound CHEBI:17552 ChEBI SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 G protein-coupled receptor GTP BioCyc 388562 ChemSpider HMDB0000464 HMDB GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc P50148 UniProt HMDB0001273 HMDB 1.0 SMP0000749 SMPDB CHEBI:75728 ChEBI Guanine nucleotide-binding protein G(q) subunit alpha SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 Protein kinase C alpha type HMDB0001201 HMDB Interaction1 G protein-coupled receptor activates Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine diphosphate 1.0 6438587 PubChem-compound SMILES [H][C@](CO)(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC Calcium Interaction3 Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine triphosphate activates Phospholipase C, beta 1 DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) 14127-61-8 CAS SMILES [Ca++] Interaction5 DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) activates Protein kinase C Interaction4 Inositol 1,4,5-trisphosphate activates Inositol 1,4,5-trisphosphate receptor PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) Interaction6 Calcium activates Protein kinase C 86-01-1 CAS SMILES CCCCCCCCCCCCCCCCCC(=O)O[C@]([H])(COC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)COP(O)(=O)O[C@H]1C(O)C(O)C(OP(=O)(O)O)[C@@H](OP(=O)(O)O)C1O CHEBI:15996 ChEBI Calcium 1.0 Guanosine triphosphate 24768010 ChemSpider Inositol 1,4,5-trisphosphate 1.0 C6H15O15P3 Inositol 1,4,5-trisphosphate 419.96237 1.0 CHEBI:29108 ChEBI GO:0005737 GENE ONTOLOGY 146-91-8 CAS 1.0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1.0 Phospholipase C, beta 1 Inositol 1,4,5- trisphosphate receptor type 1 Protein kinase C alpha type Guanine nucleotide- binding protein G(q) Guanine nucleotide- binding protein G(q) subunit alpha Inositol 1,4,5-trisphosphate DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) Ca + Ca + GTP GDP PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) Calcium GDP GTP G protein-coupled receptor Endoplasmic Reticulum Extracellular Space Intracellular Space
Guanosine diphosphate 1.0 65914-84-3 CAS Q14643 UniProt DIACYLGLYCEROL BioCyc Inositol 1,4,5-trisphosphate receptor type 1 Endoplasmic Reticulum G protein-coupled receptor C00035 KEGG Compound C01245 KEGG Compound direct_interaction Calcium Reaction2349 false Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine diphosphate + Guanosine triphosphate → Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine triphosphate + Guanosine diphosphate LEFT_TO_RIGHT 1.0 1.0 HMDB0007170 HMDB C00044 KEGG Compound C00165 KEGG Compound Guanine nucleotide-binding protein G(q) subunit alpha SMILES O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O Cytoplasm PW000726 PathWhiz Homo sapiens 1.0 CHEBI:16595 ChEBI Q9NQ66 UniProt 439456 PubChem-compound 85166-31-0 CAS GO:0005783 GENE ONTOLOGY TransportCatalysis230 ACTIVATION Protein kinase C alpha type 53480324 PubChem-compound C00626 KEGG Compound Inositol 1,4,5-trisphosphate receptor type 1 Guanine nucleotide-binding protein G(q) subunit alpha 8977 PubChem-compound Guanine nucleotide-binding protein G(q) (Homo sapiens)_Guanosine diphosphate 6830 PubChem-compound C10H15N5O11P2 Guanosine diphosphate 443.02432 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 HMDB0001498 HMDB 1.0 266 ChemSpider Reaction2350 false PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) → DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) + Inositol 1,4,5-trisphosphate LEFT_TO_RIGHT P17252 UniProt 9606 TAXONOMY Guanosine diphosphate C10H16N5O14P3 Guanosine triphosphate 522.99066 Activation of PKC Through G Protein-Coupled Receptor Guanine nucleotide-binding protein G(q) (Homo sapiens)_Guanosine diphosphate C00076 KEGG Compound 8630 ChemSpider HMDB0010133 HMDB Guanine nucleotide-binding protein G(q) (Homo sapiens)_Guanosine triphosphate CA%2b2 BioCyc C41H72O5 DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) 644.53796 4943054 ChemSpider GO:0005886 GENE ONTOLOGY Ca Calcium 39.96259 inositol_1,4,5-trisphosphate BioCyc C47H85O19P3 PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) 1046.4897 Cell Membrane Phosphatidylinositols BioCyc 6569 ChemSpider Transport283 false Calcium (→) Transport: Homo sapiens, Cell, Endoplasmic Reticulum to Homo sapiens, Cell, Cytoplasm LEFT_TO_RIGHT 271 PubChem-compound CHEBI:17552 ChEBI SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 G protein-coupled receptor GTP BioCyc 388562 ChemSpider HMDB0000464 HMDB GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc P50148 UniProt HMDB0001273 HMDB 1.0 SMP0000749 SMPDB CHEBI:75728 ChEBI Guanine nucleotide-binding protein G(q) subunit alpha SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 Protein kinase C alpha type HMDB0001201 HMDB Interaction1 G protein-coupled receptor activates Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine diphosphate 1.0 6438587 PubChem-compound SMILES [H][C@](CO)(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC Calcium Interaction3 Guanine nucleotide-binding protein G(q) (Homo sapiens) + Guanosine triphosphate activates Phospholipase C, beta 1 DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) 14127-61-8 CAS SMILES [Ca++] Interaction5 DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) activates Protein kinase C Interaction4 Inositol 1,4,5-trisphosphate activates Inositol 1,4,5-trisphosphate receptor PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) Interaction6 Calcium activates Protein kinase C 86-01-1 CAS SMILES CCCCCCCCCCCCCCCCCC(=O)O[C@]([H])(COC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)COP(O)(=O)O[C@H]1C(O)C(O)C(OP(=O)(O)O)[C@@H](OP(=O)(O)O)C1O CHEBI:15996 ChEBI Calcium 1.0 Guanosine triphosphate 24768010 ChemSpider Inositol 1,4,5-trisphosphate 1.0 C6H15O15P3 Inositol 1,4,5-trisphosphate 419.96237 1.0 CHEBI:29108 ChEBI GO:0005737 GENE ONTOLOGY 146-91-8 CAS 1.0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1.0 Endoplasmic Reticulum PLCB1 ITPR1 PRKCA GNAQ GNAQ Inositol 1,4,5- trisphosphate DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0) Calcium Calcium Guanosine triphosphate Guanosine diphosphate PIP2(20:4(5Z,8Z,11Z,14Z)/18:0) Guanosine diphosphate Guanosine triphosphate G protein-coupled receptor