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7722-84-1 CAS C00314 KEGG Compound HMDB00017 HMDB 1.0 937 ChemSpider CHEBI:16134 ChEBI SMILES O SMILES OO CHEBI:28803 ChEBI H3N Ammonia 17.026548 SMP00024 SMPDB 2.7.1.35 false 2.7.1.35 Phosphoric acid + Pyridoxine → Pyridoxine 5'-phosphate + Water LEFT_TO_RIGHT Reaction1015 false 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate → 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate LEFT_TO_RIGHT Reaction1016 false Glycolaldehyde → Pyridoxine LEFT_TO_RIGHT 1.0 Reaction1014 false 4-Pyridoxic acid → 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate LEFT_TO_RIGHT 1.0 DIHYDROXYPHENYLGLYCOLALDEHYDE BioCyc 1004 PubChem-compound PW000053 PathWhiz Q9NVS9 UniProt PW000051 PathWhiz Pyridoxamine 5'-phosphate 66-72-8 CAS SMP00034 SMPDB Pyridoxamine SMP00032 SMPDB C8H11NO3 Pyridoxine 169.0739 1026 ChemSpider 1025 ChemSpider 1024 ChemSpider HMDB00239 HMDB 6723 PubChem-compound 1023 ChemSpider PW000042 PathWhiz 1022 ChemSpider 1021 ChemSpider 1.0 952 ChemSpider GO:0005829 GENE ONTOLOGY PYRIDOXAL_PHOSPHATE BioCyc HMDB01319 HMDB C8H9NO4 4-Pyridoxic acid 183.05316 Vitamin B6 Metabolism Ammonia PW000158 PathWhiz PW000157 PathWhiz 2.0 C8H12N2O2 Pyridoxamine 168.08987 CHEBI:16240 ChEBI PW000152 PathWhiz 1.0 Reaction1022 false Pyridoxal 5'-phosphate + Water → Phosphoric acid + Pyridoxal LEFT_TO_RIGHT Reaction1023 false Phosphoric acid + Pyridoxamine ← Pyridoxamine 5'-phosphate + Water RIGHT_TO_LEFT Reaction1021 false Pyridoxine 5'-phosphate + Water → Phosphoric acid + Pyridoxine LEFT_TO_RIGHT 529-96-4 CAS ReactionCatalysis631 ACTIVATION CPD-455 BioCyc HMDB01545 HMDB Cytosol 4-Pyridoxic acid CPD-6641 BioCyc 1.0 217 ChemSpider SMILES CC1=NC=C(CO)C(C(O)=O)=C1O PYRIDOXAMINE-5P BioCyc 7664-38-2 CAS ReactionCatalysis626 ACTIVATION SubPathwayInteraction111 SubPathway111Reaction SubPathwayReaction SubPathwayInteraction110 SubPathway110Reaction SubPathwayReaction C00009 KEGG Compound HMDB01431 HMDB C00007 KEGG Compound Pyridoxal phosphate phosphatase HMDB01555 HMDB SubPathwayInteraction106 SubPathwayReaction SubPathway106Reaction C04604 KEGG Compound SubPathwayInteraction105 SubPathwayReaction SubPathway105Reaction Pyridoxine 5'-phosphate SubPathwayInteraction108 SubPathwayReaction SubPathway108Reaction SubPathwayInteraction107 SubPathway107Reaction SubPathwayReaction C00001 KEGG Compound SubPathwayInteraction109 SubPathway109Reaction SubPathwayReaction SMILES CC1=C(O)C(CN)=C(CO)C=N1 141-46-8 CAS Glycolaldehyde Pyridoxine C00250 KEGG Compound C2H4O2 Glycolaldehyde 60.02113 ReactionCatalysis619 ACTIVATION 7664-41-7 CAS ReactionCatalysis652 ACTIVATION C00018 KEGG Compound ReactionCatalysis650 ACTIVATION CHEBI:18335 ChEBI SMP00006 SMPDB SMP00128 SMPDB SMP00008 SMPDB C8H12NO6P Pyridoxine 5'-phosphate 249.04022 222 PubChem-compound 440403 PubChem-compound C00014 KEGG Compound Extracellular Space 1.0 SMILES OP(O)(O)=O Aldehyde oxidase ReactionCatalysis647 ACTIVATION SMP00004 SMPDB CHEBI:16709 ChEBI Alkaline phosphatase, tissue-nonspecific isozyme SMP00017 SMPDB C8H10NO6P Pyridoxal 5'-phosphate 247.02457 C00027 KEGG Compound Pyridoxal PYRIDOXAL BioCyc C00266 KEGG Compound CHEBI:26078 ChEBI 54-47-7 CAS GO:0005615 GENE ONTOLOGY 1.0 ReactionCatalysis638 ACTIVATION PYRIDOXAMINE BioCyc CHEBI:16410 ChEBI HMDB03125 HMDB 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate CL:0000000 CELL TYPE ONTOLOGY Pyridoxine-5'-phosphate oxidase SMILES CC1=NC=C(COP(O)(O)=O)C(CO)=C1O SMILES CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O HYDROGEN-PEROXIDE BioCyc Phenylalanine and Tyrosine Metabolism SubPathway Valine, Leucine and Isoleucine Degradation SubPathway 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxine ← Hydrogen peroxide + Pyridoxal RIGHT_TO_LEFT 389728 ChemSpider 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxine 5'-phosphate ← Hydrogen peroxide + Pyridoxal 5'-phosphate RIGHT_TO_LEFT 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxamine + Water → Ammonia + Hydrogen peroxide + Pyridoxal LEFT_TO_RIGHT 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxamine 5'-phosphate + Water → Ammonia + Hydrogen peroxide + Pyridoxal 5'-phosphate LEFT_TO_RIGHT ReactionCatalysis664 ACTIVATION ReactionCatalysis662 ACTIVATION ReactionCatalysis660 ACTIVATION C00847 KEGG Compound 756 PubChem-compound Pyridoxal phosphate phosphatase Pyridoxal kinase 440898 PubChem-compound 65-23-6 CAS 763 ChemSpider CHEBI:17071 ChEBI ReactionCatalysis656 ACTIVATION ReactionCatalysis657 ACTIVATION ReactionCatalysis654 ACTIVATION Cell 784 PubChem-compound Pyridoxal 5'-phosphate SubPathwayInput 85-87-0 CAS Transport48 false Pyridoxamine (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Transport47 false Pyridoxal (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 7732-18-5 CAS HMDB03344 HMDB 82-82-6 CAS Pyridoxal kinase O2 Oxygen 31.98983 C8H9NO3 Pyridoxal 167.05824 AMMONIA BioCyc SMILES N Pyridoxamine 1.0 Water CHEBI:17978 ChEBI Phosphoric acid C00627 KEGG Compound Q96GD0 UniProt 2.0 HMDB02142 HMDB 7782-44-7 CAS C8H13N2O5P Pyridoxamine 5'-phosphate 248.05621 1.0 C8H7NO5 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate 197.03242 C8H7NO4 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate 181.0375 C06050 KEGG Compound 1.0 SMILES CC1=C(O)C(CO)=C(CO)C=N1 9606 TAXONOMY 962 PubChem-compound 1050 PubChem-compound HMDB06955 HMDB 1051 PubChem-compound CPD-1112 BioCyc HMDB06954 HMDB 1052 PubChem-compound PW000142 PathWhiz 1.0 1.0 PW000148 PathWhiz 979 ChemSpider HMDB00051 HMDB Hydrogen peroxide 736 ChemSpider 1053 PubChem-compound 1054 PubChem-compound 1055 PubChem-compound HMDB02111 HMDB SMILES CC1=NC=C(CO)C(C=O)=C1O SMILES O=O H3O4P Phosphoric acid 97.9769 Pyridoxal phosphate phosphatase BiologicalState2 CHEBI:15377 ChEBI C00647 KEGG Compound CHEBI:15379 ChEBI CHEBI:18405 ChEBI 1.0 Q06278 UniProt Pyridoxine-5'-phosphate oxidase CHEBI:17310 ChEBI 1.0 Pyridoxal kinase Oxygen SMILES CC1=NC=C(C=O)C(C(O)=O)=C1O SMILES CC1=NC=C(C(O)=O)C(C(O)=O)=C1O SMILES CC1=NC=C(COP(O)(O)=O)C(CN)=C1O 447-05-2 CAS O00764 UniProt P05186 UniProt C00534 KEGG Compound Aldehyde oxidase CHEBI:17405 ChEBI PYRIDOXINE-5P BioCyc 1.0 H2O Water 18.010565 1.0 H2O2 Hydrogen peroxide 34.005478 Alkaline phosphatase, tissue-nonspecific isozyme 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate HMDB01377 HMDB Porphyrin Metabolism SubPathway Sphingolipid Metabolism SubPathway Glycine and Serine Metabolism SubPathway 977 PubChem-compound 6467 ChemSpider HMDB01491 HMDB 389354 ChemSpider Pyridoxal SMILES OCC=O Reaction102 false Oxygen + Pyridoxal + Water → 4-Pyridoxic acid + Hydrogen peroxide LEFT_TO_RIGHT 2.7.1.35 false 2.7.1.35 Phosphoric acid + Pyridoxamine → Pyridoxamine 5'-phosphate + Water LEFT_TO_RIGHT 3.1.3.1 false 3.1.3.1 Pyridoxal 5'-phosphate + Water ← Phosphoric acid + Pyridoxal RIGHT_TO_LEFT Gluconeogenesis SubPathway Tyrosine Metabolism SubPathway Alkaline phosphatase, tissue- nonspecific isozyme Pyridoxine- 5'-phosphate oxidase Aldehyde oxidase Pyridoxine- 5'-phosphate oxidase Pyridoxal kinase Pyridoxal kinase Pyridoxal kinase Pyridoxine- 5'-phosphate oxidase Pyridoxine- 5'-phosphate oxidase Alkaline phosphatase, tissue- nonspecific isozyme Pyridoxal phosphate phosphatase Pyridoxal phosphate phosphatase Pyridoxal phosphate phosphatase Pyridoxal 5'-phosphate Pyridoxal Pyridoxal Pyridoxamine Pyridoxamine Pyridoxal 5'-phosphate H 2 O P i H 2 O O 2 NH 3 H 2 O 2 O 2 H 2 O 4-Pyridoxic acid H 2 O 2 2-Methyl-3- hydroxy-5- formylpyridine- 4-carboxylate 3-Hydroxy-2- methylpyridine- 4,5- dicarboxylate Glycolaldehyde Pyridoxine O 2 H 2 O 2 P i Pyridoxine 5'-phosphate H 2 O H 2 O P i P i Pyridoxamine 5'-phosphate H 2 O H 2 O O 2 NH 3 H 2 O 2 O 2 H 2 O 2 P i Pyridoxamine 5'-phosphate H 2 O Flavin Mononucleotide FAD Molybdopterin Flavin Mononucleotide Zinc Zinc Zinc Flavin Mononucleotide Flavin Mononucleotide Magnesium Magnesium Magnesium Valine, Leucine and Isoleucine Degradation Gluconeogenesis Tyrosine Metabolism Porphyrin Metabolism Sphingolipid Metabolism Glycine and Serine Metabolism Phenylalanine and Tyrosine Metabolism Extracellular Space Intracellular Space
7722-84-1 CAS C00314 KEGG Compound HMDB00017 HMDB 1.0 937 ChemSpider CHEBI:16134 ChEBI SMILES O SMILES OO CHEBI:28803 ChEBI H3N Ammonia 17.026548 http://identifiers.org/smpdb/SMP00024 SMPDB 2.7.1.35 false 2.7.1.35 Phosphoric acid + Pyridoxine → Pyridoxine 5'-phosphate + Water LEFT_TO_RIGHT Reaction1015 false 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate → 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate LEFT_TO_RIGHT Reaction1016 false Glycolaldehyde → Pyridoxine LEFT_TO_RIGHT 1.0 Reaction1014 false 4-Pyridoxic acid → 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate LEFT_TO_RIGHT 1.0 DIHYDROXYPHENYLGLYCOLALDEHYDE BioCyc 1004 PubChem-compound PW000053 PathWhiz Q9NVS9 UniProt PW000051 PathWhiz Pyridoxamine 5'-phosphate 66-72-8 CAS http://identifiers.org/smpdb/SMP00034 SMPDB Pyridoxamine http://identifiers.org/smpdb/SMP00032 SMPDB C8H11NO3 Pyridoxine 169.0739 1026 ChemSpider 1025 ChemSpider 1024 ChemSpider HMDB00239 HMDB 6723 PubChem-compound 1023 ChemSpider PW000042 PathWhiz 1022 ChemSpider 1021 ChemSpider 1.0 952 ChemSpider GO:0005829 GENE ONTOLOGY PYRIDOXAL_PHOSPHATE BioCyc HMDB01319 HMDB C8H9NO4 4-Pyridoxic acid 183.05316 Vitamin B6 Metabolism Ammonia PW000158 PathWhiz PW000157 PathWhiz 2.0 C8H12N2O2 Pyridoxamine 168.08987 CHEBI:16240 ChEBI PW000152 PathWhiz 1.0 Reaction1022 false Pyridoxal 5'-phosphate + Water → Phosphoric acid + Pyridoxal LEFT_TO_RIGHT Reaction1023 false Phosphoric acid + Pyridoxamine ← Pyridoxamine 5'-phosphate + Water RIGHT_TO_LEFT Reaction1021 false Pyridoxine 5'-phosphate + Water → Phosphoric acid + Pyridoxine LEFT_TO_RIGHT 529-96-4 CAS ReactionCatalysis631 ACTIVATION CPD-455 BioCyc HMDB01545 HMDB Cytosol 4-Pyridoxic acid CPD-6641 BioCyc 1.0 217 ChemSpider SMILES CC1=NC=C(CO)C(C(O)=O)=C1O PYRIDOXAMINE-5P BioCyc 7664-38-2 CAS ReactionCatalysis626 ACTIVATION SubPathwayInteraction111 SubPathway111Reaction SubPathwayReaction SubPathwayInteraction110 SubPathway110Reaction SubPathwayReaction C00009 KEGG Compound HMDB01431 HMDB C00007 KEGG Compound Pyridoxal phosphate phosphatase HMDB01555 HMDB SubPathwayInteraction106 SubPathwayReaction SubPathway106Reaction C04604 KEGG Compound SubPathwayInteraction105 SubPathwayReaction SubPathway105Reaction Pyridoxine 5'-phosphate SubPathwayInteraction108 SubPathwayReaction SubPathway108Reaction SubPathwayInteraction107 SubPathway107Reaction SubPathwayReaction C00001 KEGG Compound SubPathwayInteraction109 SubPathway109Reaction SubPathwayReaction SMILES CC1=C(O)C(CN)=C(CO)C=N1 141-46-8 CAS Glycolaldehyde Pyridoxine C00250 KEGG Compound C2H4O2 Glycolaldehyde 60.02113 ReactionCatalysis619 ACTIVATION 7664-41-7 CAS ReactionCatalysis652 ACTIVATION C00018 KEGG Compound ReactionCatalysis650 ACTIVATION CHEBI:18335 ChEBI http://identifiers.org/smpdb/SMP00006 SMPDB http://identifiers.org/smpdb/SMP00128 SMPDB http://identifiers.org/smpdb/SMP00008 SMPDB C8H12NO6P Pyridoxine 5'-phosphate 249.04022 222 PubChem-compound 440403 PubChem-compound C00014 KEGG Compound Extracellular Space 1.0 SMILES OP(O)(O)=O Aldehyde oxidase ReactionCatalysis647 ACTIVATION http://identifiers.org/smpdb/SMP00004 SMPDB CHEBI:16709 ChEBI Alkaline phosphatase, tissue-nonspecific isozyme http://identifiers.org/smpdb/SMP00017 SMPDB C8H10NO6P Pyridoxal 5'-phosphate 247.02457 C00027 KEGG Compound Pyridoxal PYRIDOXAL BioCyc C00266 KEGG Compound CHEBI:26078 ChEBI 54-47-7 CAS GO:0005615 GENE ONTOLOGY 1.0 ReactionCatalysis638 ACTIVATION PYRIDOXAMINE BioCyc CHEBI:16410 ChEBI HMDB03125 HMDB 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate CL:0000000 CELL TYPE ONTOLOGY Pyridoxine-5'-phosphate oxidase SMILES CC1=NC=C(COP(O)(O)=O)C(CO)=C1O SMILES CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O HYDROGEN-PEROXIDE BioCyc Phenylalanine and Tyrosine Metabolism SubPathway Valine, Leucine and Isoleucine Degradation SubPathway 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxine ← Hydrogen peroxide + Pyridoxal RIGHT_TO_LEFT 389728 ChemSpider 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxine 5'-phosphate ← Hydrogen peroxide + Pyridoxal 5'-phosphate RIGHT_TO_LEFT 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxamine + Water → Ammonia + Hydrogen peroxide + Pyridoxal LEFT_TO_RIGHT 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxamine 5'-phosphate + Water → Ammonia + Hydrogen peroxide + Pyridoxal 5'-phosphate LEFT_TO_RIGHT ReactionCatalysis664 ACTIVATION ReactionCatalysis662 ACTIVATION ReactionCatalysis660 ACTIVATION C00847 KEGG Compound 756 PubChem-compound Pyridoxal phosphate phosphatase Pyridoxal kinase 440898 PubChem-compound 65-23-6 CAS 763 ChemSpider CHEBI:17071 ChEBI ReactionCatalysis656 ACTIVATION ReactionCatalysis657 ACTIVATION ReactionCatalysis654 ACTIVATION Cell 784 PubChem-compound Pyridoxal 5'-phosphate SubPathwayInput 85-87-0 CAS Transport48 false Pyridoxamine (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Transport47 false Pyridoxal (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 7732-18-5 CAS HMDB03344 HMDB 82-82-6 CAS Pyridoxal kinase O2 Oxygen 31.98983 C8H9NO3 Pyridoxal 167.05824 AMMONIA BioCyc SMILES N Pyridoxamine 1.0 Water CHEBI:17978 ChEBI Phosphoric acid C00627 KEGG Compound Q96GD0 UniProt 2.0 HMDB02142 HMDB 7782-44-7 CAS C8H13N2O5P Pyridoxamine 5'-phosphate 248.05621 1.0 C8H7NO5 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate 197.03242 C8H7NO4 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate 181.0375 C06050 KEGG Compound 1.0 SMILES CC1=C(O)C(CO)=C(CO)C=N1 9606 TAXONOMY 962 PubChem-compound 1050 PubChem-compound HMDB06955 HMDB 1051 PubChem-compound CPD-1112 BioCyc HMDB06954 HMDB 1052 PubChem-compound PW000142 PathWhiz 1.0 1.0 PW000148 PathWhiz 979 ChemSpider HMDB00051 HMDB Hydrogen peroxide 736 ChemSpider 1053 PubChem-compound 1054 PubChem-compound 1055 PubChem-compound HMDB02111 HMDB SMILES CC1=NC=C(CO)C(C=O)=C1O SMILES O=O H3O4P Phosphoric acid 97.9769 Pyridoxal phosphate phosphatase BiologicalState2 Homo sapiens, Cell, Cytosol CHEBI:15377 ChEBI C00647 KEGG Compound CHEBI:15379 ChEBI CHEBI:18405 ChEBI 1.0 Q06278 UniProt Pyridoxine-5'-phosphate oxidase CHEBI:17310 ChEBI 1.0 Pyridoxal kinase Oxygen SMILES CC1=NC=C(C=O)C(C(O)=O)=C1O SMILES CC1=NC=C(C(O)=O)C(C(O)=O)=C1O SMILES CC1=NC=C(COP(O)(O)=O)C(CN)=C1O 447-05-2 CAS O00764 UniProt P05186 UniProt C00534 KEGG Compound Aldehyde oxidase CHEBI:17405 ChEBI PYRIDOXINE-5P BioCyc 1.0 H2O Water 18.010565 1.0 H2O2 Hydrogen peroxide 34.005478 Alkaline phosphatase, tissue-nonspecific isozyme 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate HMDB01377 HMDB Porphyrin Metabolism SubPathway Sphingolipid Metabolism SubPathway Glycine and Serine Metabolism SubPathway 977 PubChem-compound 6467 ChemSpider HMDB01491 HMDB 389354 ChemSpider Pyridoxal SMILES OCC=O Reaction102 false Oxygen + Pyridoxal + Water → 4-Pyridoxic acid + Hydrogen peroxide LEFT_TO_RIGHT 2.7.1.35 false 2.7.1.35 Phosphoric acid + Pyridoxamine → Pyridoxamine 5'-phosphate + Water LEFT_TO_RIGHT 3.1.3.1 false 3.1.3.1 Pyridoxal 5'-phosphate + Water ← Phosphoric acid + Pyridoxal RIGHT_TO_LEFT Gluconeogenesis SubPathway Tyrosine Metabolism SubPathway ALPL PNPO AOX1 PNPO PDXK PDXK PDXK PNPO PNPO ALPL PDXP PDXP PDXP Pyridoxal 5'-phosphate Pyridoxal Pyridoxal Pyridoxamine Pyridoxamine Pyridoxal 5'-phosphate Water Phosphoric acid Water Oxygen Ammonia Hydrogen peroxide Oxygen Water 4-Pyridoxic acid Hydrogen peroxide 2-Methyl-3- hydroxy-5- formylpyridine- 4-carboxylate 3-Hydroxy-2- methylpyridine- 4,5- dicarboxylate Glycolaldehyde Pyridoxine Oxygen Hydrogen peroxide Phosphoric acid Pyridoxine 5'-phosphate Water Water Phosphoric acid Phosphoric acid Pyridoxamine 5'-phosphate Water Water Oxygen Ammonia Hydrogen peroxide Oxygen Hydrogen peroxide Phosphoric acid Pyridoxamine 5'-phosphate Water Valine, Leucine and Isoleucine Degradation Gluconeogenesis Tyrosine Metabolism Porphyrin Metabolism Sphingolipid Metabolism Glycine and Serine Metabolism Phenylalanine and Tyrosine Metabolism