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HMDB01586 HMDB HMDB03403 HMDB 6022 PubChem-compound 392615 ChemSpider HMDB00258 HMDB 937 ChemSpider C6H14O12P2 Alpha-D-Glucose 1,6-bisphosphate 339.99606 HMDB00250 HMDB HMDB01341 HMDB Glucose 1,6-bisphosphate synthase GLUCURONATE BioCyc 5.3.1.9 false 5.3.1.9 Beta-D-Fructose 6-phosphate ↔ Glucose 6-phosphate REVERSIBLE 439153 PubChem-compound 88070-93-3 CAS Phosphoglucomutase-1 6556-12-3 CAS 6133 PubChem-compound C00208 KEGG Compound 4.0 ATP BioCyc Starch and Sucrose Metabolism 53188-23-1 CAS 53477771 PubChem-compound 559142 ChemSpider 1.0 SubPathwayInteraction179 SubPathwayReaction SubPathway179Reaction 5743 ChemSpider 5742 ChemSpider NADH CHEBI:17200 ChEBI 2.4.1.1 false 2.4.1.1 Glycogen + Phosphate → Amylose + Glucose 1-phosphate LEFT_TO_RIGHT SMP00040 SMPDB Sucrase-isomaltase, intestinal ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc 5.4.2.2 false 5.4.2.2 Uridine diphosphate glucose → Glucose 1-phosphate LEFT_TO_RIGHT 2.4.1.11 false 2.4.1.11 Uridine diphosphate glucose → Amylose + Uridine 5'-diphosphate LEFT_TO_RIGHT 2.7.1.106 false 2.7.1.106 Glucose 1-phosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + Alpha-D-Glucose 1,6-bisphosphate LEFT_TO_RIGHT 439177 PubChem-compound ReactionCatalysis968 ACTIVATION Beta-glucuronidase 9166684 ChemSpider ReactionCatalysis967 ACTIVATION 2.4.1.17 false 2.4.1.17 Uridine diphosphate glucuronic acid → Isovalerylglucuronide + Uridine 5'-diphosphate LEFT_TO_RIGHT 3.2.1.31 false 3.2.1.31 Isovalerylglucuronide + Water → Alcohol + D-Glucuronic acid LEFT_TO_RIGHT SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O CHEBI:28102 ChEBI 2.4.1.18 false 2.4.1.18 Amylose → Glycogen LEFT_TO_RIGHT Uridine 5'-diphosphate CPD0-971 BioCyc 53477679 PubChem-compound UDP-GLUCURONATE BioCyc 6031 PubChem-compound HMDB00127 HMDB HMDB03514 HMDB 133-89-1 CAS 704 ChemSpider 1.0 PW000152 PathWhiz C00103 KEGG Compound PW000150 PathWhiz 1,4-alpha-glucan-branching enzyme 1.0 2.0 439165 PubChem-compound PPI BioCyc Uridine 5'-diphosphate SMP00058 SMPDB Reaction1266 false Alpha-D-Glucose + D-Fructose ← Sucrose + Water RIGHT_TO_LEFT 1.0 ReactionCatalysis994 ACTIVATION C15H22N2O18P2 Uridine diphosphate glucuronic acid 580.0343 ReactionCatalysis992 ACTIVATION 1.0 5768 ChemSpider 389526 ChemSpider 59-56-3 CAS C3H8O10P2 Glyceric acid 1,3-biphosphate 265.95926 444791 PubChem-compound Cytosol Transport64 false Alpha-D-Glucose (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT C00236 KEGG Compound Transport63 false D-Fructose (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 388311 ChemSpider 1.0 C00597 KEGG Compound Transport66 false D-Maltose (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Transport65 false Glycogen (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 1.0 Reaction1296 false 4 Amylose → 2 Alpha-D-Glucose + Glycogen LEFT_TO_RIGHT Reaction1294 false Dextrin → 3 Alpha-D-Glucose LEFT_TO_RIGHT 3.2.1.1 false 3.2.1.1 Glycogen → Dextrin LEFT_TO_RIGHT ReactionCatalysis988 ACTIVATION ReactionCatalysis986 ACTIVATION ReactionCatalysis987 ACTIVATION C6H12O6 D-Fructose 180.06339 ReactionCatalysis982 ACTIVATION C00009 KEGG Compound C00008 KEGG Compound C00001 KEGG Compound Reaction1290 false 4 Alpha-D-Glucose → Glycogen LEFT_TO_RIGHT Beta-D-Glucuronides BioCyc CHEBI:18361 ChEBI 1.0 HMDB03971 HMDB C00004 KEGG Compound 388322 ChemSpider CHEBI:18367 ChEBI C00003 KEGG Compound 1032 ChemSpider C00002 KEGG Compound Q6PCE3 UniProt UDP-glucuronosyltransferase 2B11 C6H12O6 Alpha-D-Glucose 180.06339 GLC-1-P BioCyc HMDB01429 HMDB 1.0 C24H42O21 Glycogen 666.22186 HMDB01401 HMDB 388775 ChemSpider C21H28N7O14P2 NAD 664.11694 SMP00128 SMPDB FRUCTOSE-6P BioCyc C00015 KEGG Compound Extracellular Space Alpha-D-Glucose C00013 KEGG Compound Glycogen debranching enzyme Glycogen phosphorylase, liver form 6.0 Glycolysis SubPathway C00029 KEGG Compound P54840 UniProt 62698 PubChem-compound P52789 UniProt 56-65-5 CAS 53-84-9 CAS O75310 UniProt C00267 KEGG Compound Gluconeogenesis SubPathway CL:0000000 CELL TYPE ONTOLOGY C02336 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Beta-glucuronidase SMILES OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O P06737 UniProt CHEBI:28087 ChEBI 2.0 10991489 PubChem-compound SMILES [O-]P([O-])(=O)OP([O-])([O-])=O P06744 UniProt C18H32O16 Dextrin 504.16904 C11H18O8 Isovalerylglucuronide 278.10016 HMDB00660 HMDB C00167 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Sucrose 1.0 1.0 9004-53-9 CAS C9H14N2O12P2 Uridine 5'-diphosphate 404.0022 HMDB00538 HMDB Isovalerylglucuronide UTP BioCyc 5903 ChemSpider C3H7O7P 3-Phosphoglyceric acid 185.99294 Hexokinase-2 7732-18-5 CAS Glucokinase CHEBI:16077 ChEBI CHEBI:4170 ChEBI C00182 KEGG Compound 492-62-6 CAS 1.0 16522 ChemSpider 2.7.7.9 false 2.7.7.9 Glucose 1-phosphate + Uridine triphosphate → Pyrophosphate + Uridine diphosphate glucose LEFT_TO_RIGHT 1.1.1.22 false 1.1.1.22 2 NAD + Uridine diphosphate glucose + Water → 2 NADH + Uridine diphosphate glucuronic acid LEFT_TO_RIGHT NAD CHEBI:18148 ChEBI BiologicalState15 5.4.2.2 false 5.4.2.2 Glucose 1-phosphate ↔ Glucose 6-phosphate REVERSIBLE BiologicalState14 C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 DPG BioCyc CHEBI:16084 ChEBI 2.0 1.0 1.0 BiologicalState18 C00191 KEGG Compound 663 ChemSpider Alpha-D-Glucose 9005-82-7 CAS CHEBI:17050 ChEBI C14H26O11 Amylose 370.14752 HMDB00757 HMDB 3-Phosphoglyceric acid 962 PubChem-compound C12H22O11 D-Maltose 342.1162 724 PubChem-compound 1.0 5800 ChemSpider 58-98-0 CAS C00075 KEGG Compound BiologicalState9 5809 ChemSpider BiologicalState2 14265-44-2 CAS Glucose-6-phosphate isomerase 58-64-0 CAS C00089 KEGG Compound C6H13O9P Glucose 1-phosphate 260.02972 1.0 C00092 KEGG Compound 71358 ChemSpider G3P BioCyc Glucose-6-phosphate isomerase Glycogen phosphorylase, liver form D-Fructose CHEBI:47937 ChEBI 644102 PubChem-compound Alpha-amylase 1 56-73-5 CAS Phosphoglucomutase-1 1.0 H2O Water 18.010565 NADH BioCyc SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O O43451 UniProt Beta-D-Fructose 6-phosphate SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O NAD BioCyc 3.0 1.0 1.0 SMILES OC[C@@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O 1.0 820-11-1 CAS SMILES O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O SUCROSE BioCyc CPD-535 BioCyc Glycogen debranching enzyme 1.0 SMILES O P35573 UniProt HMDB00807 HMDB 439709 PubChem-compound 2616-64-0 CAS Alpha-amylase 1 Glucokinase 1981-49-3 CAS 10139-18-1 CAS Isovalerylglucuronide CHEBI:15846 ChEBI HMDB00935 HMDB ADP BioCyc Lysosome Alcohol C05345 KEGG Compound GO:0005829 GENE ONTOLOGY HMDB02091 HMDB P14410 UniProt HMDB00902 HMDB CHEBI:16908 ChEBI CHEBI:15713 ChEBI Pyrophosphate O4P Phosphate 94.95342 SMILES CC(C)CC(=O)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O 5988 PubChem-compound SMILES OC[C@H]1OC(O[C@H]2[C@H](O)[C@@H](O)C(O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]3CO)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O 1.0 Q04446 UniProt UTP--glucose-1-phosphate uridylyltransferase 137383 PubChem-compound UDP-glucose 6-dehydrogenase Amylose O60701 UniProt SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O P04745 UniProt UDP-glucose 6-dehydrogenase Hexokinase-2 UDP-glucose 6-dehydrogenase Glucose 1-phosphate 1,4-alpha-glucan-branching enzyme 683 PubChem-compound C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc 58-68-4 CAS C9H15N2O15P3 Uridine triphosphate 483.96854 SMILES [O-]P([O-])([O-])=O GO:0005886 GENE ONTOLOGY 1.0 GO:0005764 GENE ONTOLOGY UTP--glucose-1-phosphate uridylyltransferase D-Maltose C6H13O9P Beta-D-Fructose 6-phosphate 260.02972 C6H10O7 D-Glucuronic acid 194.04265 17473 PubChem-compound Maltase-glucoamylase, intestinal P35557 UniProt 1.0 SMILES OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O Alpha-D-Glucose 1,6-bisphosphate 440641 PubChem-compound O7P2 Pyrophosphate 173.91193 1.0 5958 PubChem-compound C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound C12H22O11 Sucrose 342.1162 74362 ChemSpider SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 Glycogen [starch] synthase, liver Adenosine triphosphate GO:0005615 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 P36871 UniProt CHEBI:17925 ChEBI Glucose 1,6-bisphosphate synthase 56445 ChemSpider UTP--glucose-1-phosphate uridylyltransferase Endoplasmic Reticulum P08236 UniProt D-Maltose SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc SMILES OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 5682 ChemSpider UDP BioCyc CHEBI:28645 ChEBI 4.0 9005-79-2 CAS C00718 KEGG Compound 2.0 C6H13O9P Glucose 6-phosphate 260.02972 14000-31-8 CAS C00721 KEGG Compound Glycogen CHEBI:42717 ChEBI CHEBI:17992 ChEBI Phosphoglucomutase-1 Adenosine diphosphate SMILES OC(COP(O)(O)=O)C(=O)OP(O)(O)=O Uridine triphosphate Cell HMDB06857 HMDB D-Fructose HMDB03345 HMDB CHEBI:15422 ChEBI SMILES O[C@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H](OP(O)(O)=O)[C@@H]1O 388299 ChemSpider Uridine diphosphate glucuronic acid 1.0 UDP-glucuronosyltransferase 2B11 Glucose 1-phosphate 1.0 GO:0005783 GENE ONTOLOGY Water Water 82400 PubChem-compound 69-79-4 CAS Uridine diphosphate glucose CHEBI:16761 ChEBI GLC-6-P BioCyc Reaction1303 false D-Maltose → 2 Alpha-D-Glucose LEFT_TO_RIGHT 1.0 Reaction1300 false D-Maltose → 2 Alpha-D-Glucose LEFT_TO_RIGHT 9606 TAXONOMY Glucose 6-phosphate SubPathwayInput D-Glucuronic acid PW000146 PathWhiz Uridine diphosphate glucose Glycogen [starch] synthase, liver Uridine diphosphate glucuronic acid SMILES OC(COP(O)(O)=O)C(O)=O Dextrin HMDB00295 HMDB 5893 PubChem-compound HMDB02111 HMDB Alcohol ReactionCatalysis1005 ACTIVATION ReactionCatalysis1007 ACTIVATION 1.0 ReactionCatalysis1009 ACTIVATION CHEBI:30879 ChEBI 2.7.1.1 false 2.7.1.1 Adenosine triphosphate + D-Fructose → Adenosine diphosphate + Beta-D-Fructose 6-phosphate LEFT_TO_RIGHT 2.7.1.2 false 2.7.1.2 Adenosine triphosphate + Alpha-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate LEFT_TO_RIGHT CHEBI:15377 ChEBI Cell Membrane 121058 ChemSpider Glucose-6-phosphate isomerase MALTOSE BioCyc HMDB01270 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Glyceric acid 1,3-biphosphate Phosphate ReactionCatalysis1015 ACTIVATION ReactionCatalysis1018 ACTIVATION SubPathwayInteraction180 SubPathway180Reaction SubPathwayReaction SMILES COC1OC(CO)C(OC2OC(CO)C(OC)C(O)C2O)C(O)C1O 79025 PubChem-compound 1.0 ReactionCatalysis1011 ACTIVATION ReactionCatalysis377 ACTIVATION HMDB01487 HMDB ReactionCatalysis375 ACTIVATION ReactionCatalysis376 ACTIVATION ReactionCatalysis374 ACTIVATION SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O Maltase-glucoamylase, intestinal 1.0 1.0 Glycogen ReactionCatalysis2112 ACTIVATION ReactionCatalysis2113 ACTIVATION 63-39-8 CAS 1061 PubChem-compound Q16851 UniProt 57-50-1 CAS CHEBI:17659 ChEBI C00660 KEGG Compound Maltase-glucoamylase, intestinal SMILES OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O HMDB00163 HMDB HMDB00285 HMDB HMDB00286 HMDB Sucrase-isomaltase, intestinal SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O 8.0 Hexokinase-2 Glucose-6- phosphate isomerase Glucokinase Sucrase- isomaltase, intestinal Phosphoglucomutase- 1 Glucose 1,6- bisphosphate synthase UTP--glucose- 1-phosphate uridylyltransferase Phosphoglucomutase- 1 Glycogen [starch] synthase, liver 1,4-alpha- glucan- branching enzyme Maltase- glucoamylase, intestinal Alpha-amylase 1 Maltase- glucoamylase, intestinal Glycogen debranching enzyme Maltase- glucoamylase, intestinal Glycogen debranching enzyme UDP-glucose 6-dehydrogenase Glycogen phosphorylase, liver form UDP- glucuronosyltransferase 2B11 Beta- glucuronidase Glucose 6-phosphate D-Fructose D-Fructose Alpha-D-Glucose Alpha-D-Glucose Glycogen Glycogen D-Maltose D-Maltose ATP ADP Beta-D-Fructose 6-phosphate ATP ADP Sucrose H 2 O Glucose 1-phosphate Glyceric acid 1,3-biphosphate Alpha-D-Glucose 1,6- bisphosphate 3- Phosphoglyceric acid Uridine triphosphate Uridine diphosphate glucose PP i Amylose Uridine 5'-diphosphate Alpha-D-Glucose Dextrin Alpha-D-Glucose Alpha-D-Glucose NAD H 2 O Uridine diphosphate glucuronic acid NADH P i Glucose 1-phosphate Isovalerylglucuronide Uridine 5'-diphosphate H 2 O D-Glucuronic acid Magnesium Magnesium Calcium Chloride ion Pyridoxal 5'-phosphate Alcohol Glycolysis Gluconeogenesis Intracellular space Extracellular space Mitochondria Endoplasmic Reticulum Lysosome
HMDB01586 HMDB HMDB03403 HMDB 6022 PubChem-compound 392615 ChemSpider HMDB00258 HMDB 937 ChemSpider C6H14O12P2 Alpha-D-Glucose 1,6-bisphosphate 339.99606 HMDB00250 HMDB HMDB01341 HMDB Glucose 1,6-bisphosphate synthase GLUCURONATE BioCyc 5.3.1.9 false 5.3.1.9 Beta-D-Fructose 6-phosphate ↔ Glucose 6-phosphate REVERSIBLE 439153 PubChem-compound 88070-93-3 CAS Phosphoglucomutase-1 6556-12-3 CAS 6133 PubChem-compound C00208 KEGG Compound 4.0 ATP BioCyc Starch and Sucrose Metabolism 53188-23-1 CAS 53477771 PubChem-compound 559142 ChemSpider 1.0 SubPathwayInteraction179 SubPathwayReaction SubPathway179Reaction 5743 ChemSpider 5742 ChemSpider NADH CHEBI:17200 ChEBI 2.4.1.1 false 2.4.1.1 Glycogen + Phosphate → Amylose + Glucose 1-phosphate LEFT_TO_RIGHT http://identifiers.org/smpdb/SMP00040 SMPDB Sucrase-isomaltase, intestinal ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc 5.4.2.2 false 5.4.2.2 Uridine diphosphate glucose → Glucose 1-phosphate LEFT_TO_RIGHT 2.4.1.11 false 2.4.1.11 Uridine diphosphate glucose → Amylose + Uridine 5'-diphosphate LEFT_TO_RIGHT 2.7.1.106 false 2.7.1.106 Glucose 1-phosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + Alpha-D-Glucose 1,6-bisphosphate LEFT_TO_RIGHT 439177 PubChem-compound ReactionCatalysis968 ACTIVATION Beta-glucuronidase 9166684 ChemSpider ReactionCatalysis967 ACTIVATION 2.4.1.17 false 2.4.1.17 Uridine diphosphate glucuronic acid → Isovalerylglucuronide + Uridine 5'-diphosphate LEFT_TO_RIGHT 3.2.1.31 false 3.2.1.31 Isovalerylglucuronide + Water → Alcohol + D-Glucuronic acid LEFT_TO_RIGHT SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O CHEBI:28102 ChEBI 2.4.1.18 false 2.4.1.18 Amylose → Glycogen LEFT_TO_RIGHT Uridine 5'-diphosphate CPD0-971 BioCyc 53477679 PubChem-compound UDP-GLUCURONATE BioCyc 6031 PubChem-compound HMDB00127 HMDB HMDB03514 HMDB 133-89-1 CAS 704 ChemSpider 1.0 PW000152 PathWhiz C00103 KEGG Compound PW000150 PathWhiz 1,4-alpha-glucan-branching enzyme 1.0 2.0 439165 PubChem-compound PPI BioCyc Uridine 5'-diphosphate http://identifiers.org/smpdb/SMP00058 SMPDB Reaction1266 false Alpha-D-Glucose + D-Fructose ← Sucrose + Water RIGHT_TO_LEFT 1.0 ReactionCatalysis994 ACTIVATION C15H22N2O18P2 Uridine diphosphate glucuronic acid 580.0343 ReactionCatalysis992 ACTIVATION 1.0 5768 ChemSpider 389526 ChemSpider 59-56-3 CAS C3H8O10P2 Glyceric acid 1,3-biphosphate 265.95926 444791 PubChem-compound Cytosol Transport64 false Alpha-D-Glucose (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT C00236 KEGG Compound Transport63 false D-Fructose (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 388311 ChemSpider 1.0 C00597 KEGG Compound Transport66 false D-Maltose (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Transport65 false Glycogen (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 1.0 Reaction1296 false 4 Amylose → 2 Alpha-D-Glucose + Glycogen LEFT_TO_RIGHT Reaction1294 false Dextrin → 3 Alpha-D-Glucose LEFT_TO_RIGHT 3.2.1.1 false 3.2.1.1 Glycogen → Dextrin LEFT_TO_RIGHT ReactionCatalysis988 ACTIVATION ReactionCatalysis986 ACTIVATION ReactionCatalysis987 ACTIVATION C6H12O6 D-Fructose 180.06339 ReactionCatalysis982 ACTIVATION C00009 KEGG Compound C00008 KEGG Compound C00001 KEGG Compound Reaction1290 false 4 Alpha-D-Glucose → Glycogen LEFT_TO_RIGHT Beta-D-Glucuronides BioCyc CHEBI:18361 ChEBI 1.0 HMDB03971 HMDB C00004 KEGG Compound 388322 ChemSpider CHEBI:18367 ChEBI C00003 KEGG Compound 1032 ChemSpider C00002 KEGG Compound Q6PCE3 UniProt UDP-glucuronosyltransferase 2B11 C6H12O6 Alpha-D-Glucose 180.06339 GLC-1-P BioCyc HMDB01429 HMDB 1.0 C24H42O21 Glycogen 666.22186 HMDB01401 HMDB 388775 ChemSpider C21H28N7O14P2 NAD 664.11694 http://identifiers.org/smpdb/SMP00128 SMPDB FRUCTOSE-6P BioCyc C00015 KEGG Compound Extracellular Space Alpha-D-Glucose C00013 KEGG Compound Glycogen debranching enzyme Glycogen phosphorylase, liver form 6.0 Glycolysis SubPathway C00029 KEGG Compound P54840 UniProt 62698 PubChem-compound P52789 UniProt 56-65-5 CAS 53-84-9 CAS O75310 UniProt C00267 KEGG Compound Gluconeogenesis SubPathway CL:0000000 CELL TYPE ONTOLOGY C02336 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Beta-glucuronidase SMILES OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O P06737 UniProt CHEBI:28087 ChEBI 2.0 10991489 PubChem-compound SMILES [O-]P([O-])(=O)OP([O-])([O-])=O P06744 UniProt C18H32O16 Dextrin 504.16904 C11H18O8 Isovalerylglucuronide 278.10016 HMDB00660 HMDB C00167 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Sucrose 1.0 1.0 9004-53-9 CAS C9H14N2O12P2 Uridine 5'-diphosphate 404.0022 HMDB00538 HMDB Isovalerylglucuronide UTP BioCyc 5903 ChemSpider C3H7O7P 3-Phosphoglyceric acid 185.99294 Hexokinase-2 7732-18-5 CAS Glucokinase CHEBI:16077 ChEBI CHEBI:4170 ChEBI C00182 KEGG Compound 492-62-6 CAS 1.0 16522 ChemSpider 2.7.7.9 false 2.7.7.9 Glucose 1-phosphate + Uridine triphosphate → Pyrophosphate + Uridine diphosphate glucose LEFT_TO_RIGHT 1.1.1.22 false 1.1.1.22 2 NAD + Uridine diphosphate glucose + Water → 2 NADH + Uridine diphosphate glucuronic acid LEFT_TO_RIGHT NAD CHEBI:18148 ChEBI BiologicalState15 Homo sapiens, Extracellular Space 5.4.2.2 false 5.4.2.2 Glucose 1-phosphate ↔ Glucose 6-phosphate REVERSIBLE BiologicalState14 Homo sapiens, Cell Membrane C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 DPG BioCyc CHEBI:16084 ChEBI 2.0 1.0 1.0 BiologicalState18 Homo sapiens, Cell, Endoplasmic Reticulum C00191 KEGG Compound 663 ChemSpider Alpha-D-Glucose 9005-82-7 CAS CHEBI:17050 ChEBI C14H26O11 Amylose 370.14752 HMDB00757 HMDB 3-Phosphoglyceric acid 962 PubChem-compound C12H22O11 D-Maltose 342.1162 724 PubChem-compound 1.0 5800 ChemSpider 58-98-0 CAS C00075 KEGG Compound BiologicalState9 Homo sapiens, Cell, Lysosome 5809 ChemSpider BiologicalState2 Homo sapiens, Cell, Cytosol 14265-44-2 CAS Glucose-6-phosphate isomerase 58-64-0 CAS C00089 KEGG Compound C6H13O9P Glucose 1-phosphate 260.02972 1.0 C00092 KEGG Compound 71358 ChemSpider G3P BioCyc Glucose-6-phosphate isomerase Glycogen phosphorylase, liver form D-Fructose CHEBI:47937 ChEBI 644102 PubChem-compound Alpha-amylase 1 56-73-5 CAS Phosphoglucomutase-1 1.0 H2O Water 18.010565 NADH BioCyc SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O O43451 UniProt Beta-D-Fructose 6-phosphate SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O NAD BioCyc 3.0 1.0 1.0 SMILES OC[C@@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O 1.0 820-11-1 CAS SMILES O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O SUCROSE BioCyc CPD-535 BioCyc Glycogen debranching enzyme 1.0 SMILES O P35573 UniProt HMDB00807 HMDB 439709 PubChem-compound 2616-64-0 CAS Alpha-amylase 1 Glucokinase 1981-49-3 CAS 10139-18-1 CAS Isovalerylglucuronide CHEBI:15846 ChEBI HMDB00935 HMDB ADP BioCyc Lysosome Alcohol C05345 KEGG Compound GO:0005829 GENE ONTOLOGY HMDB02091 HMDB P14410 UniProt HMDB00902 HMDB CHEBI:16908 ChEBI CHEBI:15713 ChEBI Pyrophosphate O4P Phosphate 94.95342 SMILES CC(C)CC(=O)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O 5988 PubChem-compound SMILES OC[C@H]1OC(O[C@H]2[C@H](O)[C@@H](O)C(O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]3CO)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O 1.0 Q04446 UniProt UTP--glucose-1-phosphate uridylyltransferase 137383 PubChem-compound UDP-glucose 6-dehydrogenase Amylose O60701 UniProt SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O P04745 UniProt UDP-glucose 6-dehydrogenase Hexokinase-2 UDP-glucose 6-dehydrogenase Glucose 1-phosphate 1,4-alpha-glucan-branching enzyme 683 PubChem-compound C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc 58-68-4 CAS C9H15N2O15P3 Uridine triphosphate 483.96854 SMILES [O-]P([O-])([O-])=O GO:0005886 GENE ONTOLOGY 1.0 GO:0005764 GENE ONTOLOGY UTP--glucose-1-phosphate uridylyltransferase D-Maltose C6H13O9P Beta-D-Fructose 6-phosphate 260.02972 C6H10O7 D-Glucuronic acid 194.04265 17473 PubChem-compound Maltase-glucoamylase, intestinal P35557 UniProt 1.0 SMILES OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O Alpha-D-Glucose 1,6-bisphosphate 440641 PubChem-compound O7P2 Pyrophosphate 173.91193 1.0 5958 PubChem-compound C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound C12H22O11 Sucrose 342.1162 74362 ChemSpider SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 Glycogen [starch] synthase, liver Adenosine triphosphate GO:0005615 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 P36871 UniProt CHEBI:17925 ChEBI Glucose 1,6-bisphosphate synthase 56445 ChemSpider UTP--glucose-1-phosphate uridylyltransferase Endoplasmic Reticulum P08236 UniProt D-Maltose SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc SMILES OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]2O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 5682 ChemSpider UDP BioCyc CHEBI:28645 ChEBI 4.0 9005-79-2 CAS C00718 KEGG Compound 2.0 C6H13O9P Glucose 6-phosphate 260.02972 14000-31-8 CAS C00721 KEGG Compound Glycogen CHEBI:42717 ChEBI CHEBI:17992 ChEBI Phosphoglucomutase-1 Adenosine diphosphate SMILES OC(COP(O)(O)=O)C(=O)OP(O)(O)=O Uridine triphosphate Cell HMDB06857 HMDB D-Fructose HMDB03345 HMDB CHEBI:15422 ChEBI SMILES O[C@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H](OP(O)(O)=O)[C@@H]1O 388299 ChemSpider Uridine diphosphate glucuronic acid 1.0 UDP-glucuronosyltransferase 2B11 Glucose 1-phosphate 1.0 GO:0005783 GENE ONTOLOGY Water Water 82400 PubChem-compound 69-79-4 CAS Uridine diphosphate glucose CHEBI:16761 ChEBI GLC-6-P BioCyc Reaction1303 false D-Maltose → 2 Alpha-D-Glucose LEFT_TO_RIGHT 1.0 Reaction1300 false D-Maltose → 2 Alpha-D-Glucose LEFT_TO_RIGHT 9606 TAXONOMY Glucose 6-phosphate SubPathwayInput D-Glucuronic acid PW000146 PathWhiz Uridine diphosphate glucose Glycogen [starch] synthase, liver Uridine diphosphate glucuronic acid SMILES OC(COP(O)(O)=O)C(O)=O Dextrin HMDB00295 HMDB 5893 PubChem-compound HMDB02111 HMDB Alcohol ReactionCatalysis1005 ACTIVATION ReactionCatalysis1007 ACTIVATION 1.0 ReactionCatalysis1009 ACTIVATION CHEBI:30879 ChEBI 2.7.1.1 false 2.7.1.1 Adenosine triphosphate + D-Fructose → Adenosine diphosphate + Beta-D-Fructose 6-phosphate LEFT_TO_RIGHT 2.7.1.2 false 2.7.1.2 Adenosine triphosphate + Alpha-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate LEFT_TO_RIGHT CHEBI:15377 ChEBI Cell Membrane 121058 ChemSpider Glucose-6-phosphate isomerase MALTOSE BioCyc HMDB01270 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Glyceric acid 1,3-biphosphate Phosphate ReactionCatalysis1015 ACTIVATION ReactionCatalysis1018 ACTIVATION SubPathwayInteraction180 SubPathway180Reaction SubPathwayReaction SMILES COC1OC(CO)C(OC2OC(CO)C(OC)C(O)C2O)C(O)C1O 79025 PubChem-compound 1.0 ReactionCatalysis1011 ACTIVATION ReactionCatalysis377 ACTIVATION HMDB01487 HMDB ReactionCatalysis375 ACTIVATION ReactionCatalysis376 ACTIVATION ReactionCatalysis374 ACTIVATION SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O Maltase-glucoamylase, intestinal 1.0 1.0 Glycogen ReactionCatalysis2112 ACTIVATION ReactionCatalysis2113 ACTIVATION 63-39-8 CAS 1061 PubChem-compound Q16851 UniProt 57-50-1 CAS CHEBI:17659 ChEBI C00660 KEGG Compound Maltase-glucoamylase, intestinal SMILES OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O HMDB00163 HMDB HMDB00285 HMDB HMDB00286 HMDB Sucrase-isomaltase, intestinal SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O 8.0