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Endoplasmic Reticulum CL:0000000 CELL TYPE ONTOLOGY 389681 ChemSpider 937 ChemSpider HMDB00250 HMDB SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](N)C(O)=O)[C@@]1([H])NC(=O)N2 SMILES O CHEBI:15956 ChEBI SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS Lysine Degradation SubPathway 1.0 HMDB04220 HMDB Transport12 false Biocytin (→) Transport: Homo sapiens, Cell, Cytoplasm to Homo sapiens, Extracellular Space LEFT_TO_RIGHT ATP BioCyc 58-85-5 CAS HMDB03134 HMDB 5962 PubChem-compound Transport11 false Biotin (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytoplasm LEFT_TO_RIGHT C00047 KEGG Compound P43251 UniProt 1.0 P50747 UniProt 559142 ChemSpider Cytoplasm HMDB00538 HMDB 75634 ChemSpider SMP00037 SMPDB Biotin-Carboxyl Carrying Protein Cell 1.0 CHEBI:18019 ChEBI 5747 ChemSpider CHEBI:15422 ChEBI ReactionCatalysis173 ACTIVATION ReactionCatalysis174 ACTIVATION ReactionCatalysis171 ACTIVATION ReactionCatalysis172 ACTIVATION 5742 ChemSpider 7732-18-5 CAS Biotin-Carboxyl Carrying Protein LYS BioCyc Water GO:0005783 GENE ONTOLOGY Biocytin 1.0 BiologicalState15 C10H16N5O13P3 Adenosine triphosphate 506.99576 Q9Y6A9 UniProt Biotin--protein ligase 440839 PubChem-compound 1.0 1.0 Biotin-Carboxyl Carrying Protein Pyrophosphate BiologicalState18 171548 PubChem-compound PPI BioCyc 576-19-2 CAS PW000029 PathWhiz SMP00174 SMPDB C10H16N2O3S Biotin 244.08817 9606 TAXONOMY 962 PubChem-compound Biotin C05921 KEGG Compound Biotinyl-5'-AMP Biocytin 1.0 HMDB02111 HMDB 1.0 Biocytin 56-87-1 CAS Reaction676 false Biotinyl-5'-AMP → Biotin-Carboxyl Carrying Protein LEFT_TO_RIGHT BiologicalState8 3.4.-.- false 3.4.-.- Biotin-Carboxyl Carrying Protein → Biocytin LEFT_TO_RIGHT Reaction674 false Adenosine triphosphate + Biotin → Biotinyl-5'-AMP + Pyrophosphate LEFT_TO_RIGHT C20H28N7O9PS Biotinyl-5'-AMP 573.1407 3.5.1.12 false 3.5.1.12 Biocytin + Water → Biotin + L-Lysine LEFT_TO_RIGHT CHEBI:27870 ChEBI CHEBI:15377 ChEBI C6H14N2O2 L-Lysine 146.10553 C00001 KEGG Compound PW000092 PathWhiz SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O BIOTIN BioCyc C00120 KEGG Compound Biotinidase HMDB00182 HMDB CHEBI:18361 ChEBI 1.0 C00002 KEGG Compound 149962 ChemSpider Signal peptidase complex subunit 1 SMILES [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2 7098660 PubChem-compound 644102 PubChem-compound 1.0 O00763 UniProt Adenosine triphosphate 1.0 HMDB00030 HMDB Biotinidase C00013 KEGG Compound Extracellular Space O7P2 Pyrophosphate 173.91193 Biotin--protein ligase C05552 KEGG Compound H2O Water 18.010565 5957 PubChem-compound C16H28N4O4S Biocytin 372.18314 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OC(=O)CCCC[C@@H]2SCC3NC(=O)NC23)[C@@H](O)[C@H]1O Signal peptidase complex subunit 1 SubPathwayInteraction801 SubPathwayReaction SubPathway801Reaction SMILES NCCCC[C@H](N)C(O)=O Biotin 56-65-5 CAS 4130-20-5 CAS Biotinidase Deficiency L-Lysine SubPathwayInput GO:0005615 GENE ONTOLOGY GO:0005737 GENE ONTOLOGY 1.0 Biotin--protein ligase Biotinidase Biotin--protein ligase Signal peptidase complex subunit 1 L-Lysine Biotin Biotin Biocytin Biocytin ATP Biotinyl-5'-AMP PP i H 2 O Biotin-Carboxyl Carrying Protein Lysine Degradation Intracellular Space Extracellular Space Endoplastic Reticulum
Endoplasmic Reticulum CL:0000000 CELL TYPE ONTOLOGY 389681 ChemSpider 937 ChemSpider HMDB00250 HMDB SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](N)C(O)=O)[C@@]1([H])NC(=O)N2 SMILES O CHEBI:15956 ChEBI SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS Lysine Degradation SubPathway 1.0 HMDB04220 HMDB Transport12 false Biocytin (→) Transport: Homo sapiens, Cell, Cytoplasm to Homo sapiens, Extracellular Space LEFT_TO_RIGHT ATP BioCyc 58-85-5 CAS HMDB03134 HMDB 5962 PubChem-compound Transport11 false Biotin (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytoplasm LEFT_TO_RIGHT C00047 KEGG Compound P43251 UniProt 1.0 P50747 UniProt 559142 ChemSpider Cytoplasm HMDB00538 HMDB 75634 ChemSpider http://identifiers.org/smpdb/SMP00037 SMPDB Biotin-Carboxyl Carrying Protein Cell 1.0 CHEBI:18019 ChEBI 5747 ChemSpider CHEBI:15422 ChEBI ReactionCatalysis173 ACTIVATION ReactionCatalysis174 ACTIVATION ReactionCatalysis171 ACTIVATION ReactionCatalysis172 ACTIVATION 5742 ChemSpider 7732-18-5 CAS Biotin-Carboxyl Carrying Protein LYS BioCyc Water GO:0005783 GENE ONTOLOGY Biocytin 1.0 BiologicalState15 Homo sapiens, Extracellular Space C10H16N5O13P3 Adenosine triphosphate 506.99576 Q9Y6A9 UniProt Biotin--protein ligase 440839 PubChem-compound 1.0 1.0 Biotin-Carboxyl Carrying Protein Pyrophosphate BiologicalState18 Homo sapiens, Cell, Endoplasmic Reticulum 171548 PubChem-compound PPI BioCyc 576-19-2 CAS PW000029 PathWhiz http://identifiers.org/smpdb/SMP00174 SMPDB C10H16N2O3S Biotin 244.08817 9606 TAXONOMY 962 PubChem-compound Biotin C05921 KEGG Compound Biotinyl-5'-AMP Biocytin 1.0 HMDB02111 HMDB 1.0 Biocytin 56-87-1 CAS Reaction676 false Biotinyl-5'-AMP → Biotin-Carboxyl Carrying Protein LEFT_TO_RIGHT BiologicalState8 Homo sapiens, Cell, Cytoplasm 3.4.-.- false 3.4.-.- Biotin-Carboxyl Carrying Protein → Biocytin LEFT_TO_RIGHT Reaction674 false Adenosine triphosphate + Biotin → Biotinyl-5'-AMP + Pyrophosphate LEFT_TO_RIGHT C20H28N7O9PS Biotinyl-5'-AMP 573.1407 3.5.1.12 false 3.5.1.12 Biocytin + Water → Biotin + L-Lysine LEFT_TO_RIGHT CHEBI:27870 ChEBI CHEBI:15377 ChEBI C6H14N2O2 L-Lysine 146.10553 C00001 KEGG Compound PW000092 PathWhiz SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O BIOTIN BioCyc C00120 KEGG Compound Biotinidase HMDB00182 HMDB CHEBI:18361 ChEBI 1.0 C00002 KEGG Compound 149962 ChemSpider Signal peptidase complex subunit 1 SMILES [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2 7098660 PubChem-compound 644102 PubChem-compound 1.0 O00763 UniProt Adenosine triphosphate 1.0 HMDB00030 HMDB Biotinidase C00013 KEGG Compound Extracellular Space O7P2 Pyrophosphate 173.91193 Biotin--protein ligase C05552 KEGG Compound H2O Water 18.010565 5957 PubChem-compound C16H28N4O4S Biocytin 372.18314 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OC(=O)CCCC[C@@H]2SCC3NC(=O)NC23)[C@@H](O)[C@H]1O Signal peptidase complex subunit 1 SubPathwayInteraction801 SubPathwayReaction SubPathway801Reaction SMILES NCCCC[C@H](N)C(O)=O Biotin 56-65-5 CAS 4130-20-5 CAS Biotinidase Deficiency L-Lysine SubPathwayInput GO:0005615 GENE ONTOLOGY GO:0005737 GENE ONTOLOGY 1.0 HLCS BTD HLCS SPCS1 L-Lysine Biotin Biotin Biocytin Biocytin Adenosine triphosphate Biotinyl-5'-AMP Pyrophosphate Water Biotin-Carboxyl Carrying Protein Lysine Degradation