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Sodium/potassium-transporting ATPase subunit alpha-3 Q92536 UniProt 923 PubChem-compound C21H28O5 Aldosterone 360.19366 SMILES N[C@@H](CS)C(O)=O 937 ChemSpider Sodium/potassium-transporting ATPase subunit beta-3 TransportCatalysis98 ACTIVATION CYS BioCyc HMDB00492 HMDB Amiloride-sensitive sodium channel subunit delta P08195 UniProt SLC3A2/4F2hc Y+L amino acid transporter 2 Q07837 UniProt Sodium/potassium-transporting ATPase subunit gamma SMILES O 57-13-6 CAS Solute carrier family 22 member 2 CHEBI:33709 ChEBI SMILES [Na+] L-Cysteine SMILES [K+] Solute carrier family 12 member 6 1.0 Q4U2R8 UniProt Imino acids SMILES OC([O-])=O 1.0 Transport127 false L-Cysteine (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 1.0 HMDB00595 HMDB P05023 UniProt P05026 UniProt HCO3 BioCyc Solute carrier family 22 member 6 P14415 UniProt 4F2 cell-surface antigen heavy chain C01780 KEGG Compound 1.0 C00698 KEGG Compound Sodium- and chloride-dependent transporter XTRP3 1143 ChemSpider CHEBI:17561 ChEBI GO:0005829 GENE ONTOLOGY P51800 UniProt Y+L amino acid transporter 1 UREA BioCyc Cl Chloride ion 34.968853 ATPase, (Na+)/K+ transporting, beta 4 polypeptide 1.0 24758425 PubChem-compound 813 PubChem-compound Chloride channel protein ClC-Ka SLC3A2/4F2hc Y+L amino acid transporter 1 1.0 Aquaporin-3 Sodium/potassium ATPase SLC3A2/4F2hc Large neutral amino acids transporter small subunit 1 SLC3A2/4F2hc Large neutral amino acids transporter small subunit 2 5862 PubChem-compound Y+L amino acid transporter 2 Urea 1.0 Sodium/potassium-transporting ATPase subunit beta-2 Excitatory amino acid transporter 3 Sodium/potassium-transporting ATPase subunit beta-1 CHEBI:26271 ChEBI Amiloride-sensitive sodium channel subunit delta SMILES NC(N)=O Solute carrier family 12 member 3 Amiloride-sensitive sodium channel subunit beta CHEBI:15705 ChEBI ALDOSTERONE BioCyc P37088 UniProt Transcription/Translation SubPathway Imino acids HMDB00574 HMDB C00238 KEGG Compound 1.0 Sodium/potassium-transporting ATPase subunit gamma Aquaporin-2 L-Amino acid Cytosol 24774738 ChemSpider Aquaporin-1 Large Neutral Amino Acids SMILES [Cl-] Chloride ion Large neutral amino acids transporter small subunit 2 GO:0005886 GENE ONTOLOGY CHEBI:25697 ChEBI CHEBI:25696 ChEBI HMDB00586 HMDB 312 PubChem-compound HMDB00588 HMDB Sodium/potassium-transporting ATPase subunit beta-3 1.0 24203-36-9 CAS C00001 KEGG Compound Sodium/potassium-transporting ATPase subunit alpha-4 Transport56 false Organic Anion (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT C01330 KEGG Compound Transport59 false Chloride ion (→), Potassium (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Urea transporter 2 Transport58 false Sodium (→), Potassium (→), Chloride ion (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Transport53 false Sodium (→), Potassium (←) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Urea Transport52 false Chloride ion (→), Sodium (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT P13637 UniProt Transport55 false Water (↔) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport54 false Chloride ion (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport60 false Organic Cation (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT 1.0 Sodium-coupled neutral amino acid transporter 4 Sodium/potassium-transporting ATPase subunit alpha-1 Transport62 false Sodium (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT SMILES C[C@]12CCC(=O)C=C1CCC1C3CC[C@H](C(=O)CO)[C@]3(C[C@H](O)C21)C=O 1.0 GO:0005634 GENE ONTOLOGY Hydrogen carbonate P54710 UniProt Organic Anion Solute carrier family 12 member 6 Neutral and basic amino acid transport protein rBAT Amiloride-sensitive sodium channel subunit alpha B(0,+)-type amino acid transporter 1 Extracellular Space Sodium/potassium ATPase SubPathwayOutput Large neutral amino acids transporter small subunit 1 Q13733 UniProt P55017 UniProt Sodium- and chloride-dependent transporter XTRP3 Solute carrier family 22 member 6 4F2 cell-surface antigen heavy chain SMP00019 SMPDB Amiloride-sensitive sodium channel subunit alpha Large Neutral Amino Acids 1.0 Y+L amino acid transporter 1 5653 ChemSpider Epithelial Sodium Channel Amiloride-sensitive sodium channel subunit gamma Sodium Transport84 false Large Neutral Amino Acids (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport83 false L-Amino acid (→), Sodium (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Q01650 UniProt GO:0005615 GENE ONTOLOGY 1.0 Organic Anion Active Mineralocorticoid receptor (Homo sapiens)_Aldosterone SubPathwayInput CHEBI:29101 ChEBI Q13621 UniProt CHEBI:29103 ChEBI Sodium/potassium-transporting ATPase subunit alpha-1 PW000220 PathWhiz 3.0 P29972 UniProt Y+L amino acid transporter 2 769 PubChem-compound BiologicalState23 P08235 UniProt Sodium/potassium-transporting ATPase subunit beta-1 Amiloride-sensitive sodium channel subunit delta 52-90-4 CAS CL:0000000 CELL TYPE ONTOLOGY P41181 UniProt Aquaporin-3 Solute carrier family 12 member 3 Amiloride-sensitive sodium channel subunit beta Sodium/potassium-transporting ATPase subunit beta-2 B7ZKV8 UniProt 1.0 899 ChemSpider Excitatory amino acid transporter 3 P43005 UniProt Potassium 1.0 CHEBI:17996 ChEBI SubPathwayInteraction301 SubPathway301Reaction SubPathwayReaction TransportCatalysis29 ACTIVATION 3.0 2.0 1.0 PW000455 PathWhiz TransportCatalysis24 ACTIVATION TransportCatalysis23 ACTIVATION TransportCatalysis22 ACTIVATION Aquaporin-2 1.0 Neutral and basic amino acid transport protein rBAT/B(0,+)-type amino acid transporter 1 K%2b BioCyc TransportCatalysis28 ACTIVATION 1.0 TransportCatalysis27 ACTIVATION Imino acids P54709 UniProt 16887-00-6 CAS TransportCatalysis25 ACTIVATION Q92482 UniProt C00288 KEGG Compound CH4N2O Urea 60.032364 17341-25-2 CAS Cell Lysinuric Protein Intolerance TransportCatalysis187 ACTIVATION Aldosterone ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium-transporting ATPase subunit alpha-4 2.0 Urea transporter 2 Potassium 1.0 Sodium/potassium-transporting ATPase subunit alpha-2 TransportCatalysis33 ACTIVATION TransportCatalysis32 ACTIVATION 7732-18-5 CAS Sodium/potassium-transporting ATPase subunit alpha-1 Sodium-coupled neutral amino acid transporter 4 CHEBI:16199 ChEBI L-Amino acid Sodium/potassium-transporting ATPase subunit alpha-3 Large Neutral Amino Acids TransportCatalysis31 ACTIVATION Solute carrier family 12 member 1 TransportCatalysis30 ACTIVATION 791 ChemSpider Q969I6 UniProt Active Mineralocorticoid receptor Water Water Amiloride-sensitive sodium channel subunit alpha Solute carrier family 22 member 2 B(0,+)-type amino acid transporter 1 Epithelial Sodium Channel SubPathwayOutput BiologicalState14 Neutral and basic amino acid transport protein rBAT Organic Cation P82251 UniProt Large neutral amino acids transporter small subunit 1 306 ChemSpider Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit beta-1 Organic Anion TransportCatalysis47 ACTIVATION Mineralocorticoid receptor Amiloride-sensitive sodium channel subunit gamma 1.0 Sodium/potassium-transporting ATPase subunit beta-3 Q9UHI5 UniProt Q15849 UniProt 1.0 TransportCatalysis188 ACTIVATION 52-39-1 CAS 962 PubChem-compound 9606 TAXONOMY CHEBI:17544 ChEBI O15244 UniProt Sodium 1.0 HMDB00294 HMDB 1176 PubChem-compound Amiloride-sensitive sodium channel subunit beta HMDB02111 HMDB Organic Cation TransportCatalysis51 ACTIVATION TransportCatalysis50 ACTIVATION 2.0 Hydrogen carbonate Amiloride-sensitive sodium channel subunit gamma CHEBI:15377 ChEBI L-Cysteine Cell Membrane Q9UM01 UniProt Sodium/potassium-transporting ATPase subunit alpha-2 Q9UHW9 UniProt TransportCatalysis68 ACTIVATION C00086 KEGG Compound 1.0 Chloride ion SMP00197 SMPDB CHEBI:27584 ChEBI CPD-4521 BioCyc ATPase, (Na+)/K+ transporting, beta 4 polypeptide C3H7NO2S L-Cysteine 121.01975 HMDB00037 HMDB L-Amino acid Chloride channel protein ClC-Ka C00097 KEGG Compound TransportCatalysis71 ACTIVATION H2O Water 18.010565 TransportCatalysis73 ACTIVATION TransportCatalysis72 ACTIVATION P50993 UniProt P51168 UniProt Sodium/potassium-transporting ATPase subunit beta-2 Nucleus P51172 UniProt Transport101 false Imino acids (→), Sodium (→), Chloride ion (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT P51170 UniProt Na Sodium 22.989769 Sodium/potassium-transporting ATPase subunit alpha-2 K Potassium 38.963707 Large neutral amino acids transporter small subunit 2 Sodium/potassium-transporting ATPase subunit alpha-4 Solute carrier family 12 member 1 Organic Cation 749 ChemSpider 2.0 71-52-3 CAS 1.0 1.0 1.0 Aquaporin-1 Sodium/potassium-transporting ATPase subunit gamma Transport107 false Hydrogen carbonate (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Mineralocorticoid receptor Transport106 false Urea (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Q9NP91 UniProt CHO3 Hydrogen carbonate 60.99257 Transport108 false Hydrogen carbonate (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport103 false L-Amino acid (→), Sodium (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport105 false Urea (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 2.0 Transport104 false L-Amino acid (→), Sodium (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Amiloride- sensitive sodium channel subunit alpha Amiloride- sensitive sodium channel subunit beta Amiloride- sensitive sodium channel subunit delta Amiloride- sensitive sodium channel subunit gamma Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Solute carrier family 12 member 3 Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Chloride channel protein ClC-Ka Aquaporin-1 Aquaporin-1 Solute carrier family 12 member 1 Chloride channel protein ClC-Ka Solute carrier family 22 member 6 Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Solute carrier family 12 member 6 Solute carrier family 22 member 2 Aquaporin-2 Aquaporin-3 Amiloride- sensitive sodium channel subunit alpha Amiloride- sensitive sodium channel subunit beta Amiloride- sensitive sodium channel subunit delta Amiloride- sensitive sodium channel subunit gamma Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Excitatory amino acid transporter 3 Large neutral amino acids transporter small subunit 2 4F2 cell-surface antigen heavy chain Large neutral amino acids transporter small subunit 1 4F2 cell-surface antigen heavy chain Sodium- and chloride- dependent transporter XTRP3 Sodium-coupled neutral amino acid transporter 4 Y+L amino acid transporter 1 4F2 cell-surface antigen heavy chain Y+L amino acid transporter 2 4F2 cell-surface antigen heavy chain Neutral and basic amino acid transport protein rBAT B(0,+)-type amino acid transporter 1 Urea transporter 2 Urea transporter 2 Mineralocorticoid receptor Cl - Cl - Na + Na + Na + K + K + Cl - Cl - H 2 O H 2 O H 2 O Na + Na + K + K + Cl - Cl - Cl - Cl - Na + K + K + Cl - Cl - K + K + H 2 O H 2 O H 2 O H 2 O Na + Na + Na + Na + K + K + Na + Na + Na + Na + Cl - Cl - Na + Na + Na + Na + Na + Na + Urea Urea Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate L-Cysteine L-Cysteine Urea Aldosterone Organic Anion Organic Anion Organic Cation Organic Cation L-Amino acid L-Amino acid Large Neutral Amino Acids Large Neutral Amino Acids Large Neutral Amino Acids Large Neutral Amino Acids Imino acids Imino acids L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid Transcription/Translation PROXIMAL CONVOLUTED TUBULE LUMEN INTERSTITIUM BLADDER DISTAL CONVOLUTED TUBULE LUMEN INTERSTITIUM DESCENDING LIMB OF LOOP OF HENLE LUMEN INTERSTITIUM THICK ASCENDING LIMB OF LOOP OF HENLE LUMEN LUMEN INTERSTITIUM COLLECTING TUBULE INTERSTITIUM Nucleus
Sodium/potassium-transporting ATPase subunit alpha-3 Q92536 UniProt 923 PubChem-compound C21H28O5 Aldosterone 360.19366 SMILES N[C@@H](CS)C(O)=O 937 ChemSpider Sodium/potassium-transporting ATPase subunit beta-3 TransportCatalysis98 ACTIVATION CYS BioCyc HMDB00492 HMDB Amiloride-sensitive sodium channel subunit delta P08195 UniProt SLC3A2/4F2hc Y+L amino acid transporter 2 Q07837 UniProt Sodium/potassium-transporting ATPase subunit gamma SMILES O 57-13-6 CAS Solute carrier family 22 member 2 CHEBI:33709 ChEBI SMILES [Na+] L-Cysteine SMILES [K+] Solute carrier family 12 member 6 1.0 Q4U2R8 UniProt Imino acids SMILES OC([O-])=O 1.0 Transport127 false L-Cysteine (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 1.0 HMDB00595 HMDB P05023 UniProt P05026 UniProt HCO3 BioCyc Solute carrier family 22 member 6 P14415 UniProt 4F2 cell-surface antigen heavy chain C01780 KEGG Compound 1.0 C00698 KEGG Compound Sodium- and chloride-dependent transporter XTRP3 1143 ChemSpider CHEBI:17561 ChEBI GO:0005829 GENE ONTOLOGY P51800 UniProt Y+L amino acid transporter 1 UREA BioCyc Cl Chloride ion 34.968853 ATPase, (Na+)/K+ transporting, beta 4 polypeptide 1.0 24758425 PubChem-compound 813 PubChem-compound Chloride channel protein ClC-Ka SLC3A2/4F2hc Y+L amino acid transporter 1 1.0 Aquaporin-3 Sodium/potassium ATPase SLC3A2/4F2hc Large neutral amino acids transporter small subunit 1 SLC3A2/4F2hc Large neutral amino acids transporter small subunit 2 5862 PubChem-compound Y+L amino acid transporter 2 Urea 1.0 Sodium/potassium-transporting ATPase subunit beta-2 Excitatory amino acid transporter 3 Sodium/potassium-transporting ATPase subunit beta-1 CHEBI:26271 ChEBI Amiloride-sensitive sodium channel subunit delta SMILES NC(N)=O Solute carrier family 12 member 3 Amiloride-sensitive sodium channel subunit beta CHEBI:15705 ChEBI ALDOSTERONE BioCyc P37088 UniProt Transcription/Translation SubPathway Imino acids HMDB00574 HMDB C00238 KEGG Compound 1.0 Sodium/potassium-transporting ATPase subunit gamma Aquaporin-2 L-Amino acid Cytosol 24774738 ChemSpider Aquaporin-1 Large Neutral Amino Acids SMILES [Cl-] Chloride ion Large neutral amino acids transporter small subunit 2 GO:0005886 GENE ONTOLOGY CHEBI:25697 ChEBI CHEBI:25696 ChEBI HMDB00586 HMDB 312 PubChem-compound HMDB00588 HMDB Sodium/potassium-transporting ATPase subunit beta-3 1.0 24203-36-9 CAS C00001 KEGG Compound Sodium/potassium-transporting ATPase subunit alpha-4 Transport56 false Organic Anion (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT C01330 KEGG Compound Transport59 false Chloride ion (→), Potassium (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Urea transporter 2 Transport58 false Sodium (→), Potassium (→), Chloride ion (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Transport53 false Sodium (→), Potassium (←) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Urea Transport52 false Chloride ion (→), Sodium (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT P13637 UniProt Transport55 false Water (↔) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport54 false Chloride ion (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport60 false Organic Cation (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT 1.0 Sodium-coupled neutral amino acid transporter 4 Sodium/potassium-transporting ATPase subunit alpha-1 Transport62 false Sodium (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT SMILES C[C@]12CCC(=O)C=C1CCC1C3CC[C@H](C(=O)CO)[C@]3(C[C@H](O)C21)C=O 1.0 GO:0005634 GENE ONTOLOGY Hydrogen carbonate P54710 UniProt Organic Anion Solute carrier family 12 member 6 Neutral and basic amino acid transport protein rBAT Amiloride-sensitive sodium channel subunit alpha B(0,+)-type amino acid transporter 1 Extracellular Space Sodium/potassium ATPase SubPathwayOutput Large neutral amino acids transporter small subunit 1 Q13733 UniProt P55017 UniProt Sodium- and chloride-dependent transporter XTRP3 Solute carrier family 22 member 6 4F2 cell-surface antigen heavy chain http://identifiers.org/smpdb/SMP00019 SMPDB Amiloride-sensitive sodium channel subunit alpha Large Neutral Amino Acids 1.0 Y+L amino acid transporter 1 5653 ChemSpider Epithelial Sodium Channel Amiloride-sensitive sodium channel subunit gamma Sodium Transport84 false Large Neutral Amino Acids (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport83 false L-Amino acid (→), Sodium (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Q01650 UniProt GO:0005615 GENE ONTOLOGY 1.0 Organic Anion Active Mineralocorticoid receptor (Homo sapiens)_Aldosterone SubPathwayInput CHEBI:29101 ChEBI Q13621 UniProt CHEBI:29103 ChEBI Sodium/potassium-transporting ATPase subunit alpha-1 PW000220 PathWhiz 3.0 P29972 UniProt Y+L amino acid transporter 2 769 PubChem-compound BiologicalState23 Homo sapiens, Cell, Nucleus P08235 UniProt Sodium/potassium-transporting ATPase subunit beta-1 Amiloride-sensitive sodium channel subunit delta 52-90-4 CAS CL:0000000 CELL TYPE ONTOLOGY P41181 UniProt Aquaporin-3 Solute carrier family 12 member 3 Amiloride-sensitive sodium channel subunit beta Sodium/potassium-transporting ATPase subunit beta-2 B7ZKV8 UniProt 1.0 899 ChemSpider Excitatory amino acid transporter 3 P43005 UniProt Potassium 1.0 CHEBI:17996 ChEBI SubPathwayInteraction301 SubPathway301Reaction SubPathwayReaction TransportCatalysis29 ACTIVATION 3.0 2.0 1.0 PW000455 PathWhiz TransportCatalysis24 ACTIVATION TransportCatalysis23 ACTIVATION TransportCatalysis22 ACTIVATION Aquaporin-2 1.0 Neutral and basic amino acid transport protein rBAT/B(0,+)-type amino acid transporter 1 K%2b BioCyc TransportCatalysis28 ACTIVATION 1.0 TransportCatalysis27 ACTIVATION Imino acids P54709 UniProt 16887-00-6 CAS TransportCatalysis25 ACTIVATION Q92482 UniProt C00288 KEGG Compound CH4N2O Urea 60.032364 17341-25-2 CAS Cell Lysinuric Protein Intolerance TransportCatalysis187 ACTIVATION Aldosterone ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium-transporting ATPase subunit alpha-4 2.0 Urea transporter 2 Potassium 1.0 Sodium/potassium-transporting ATPase subunit alpha-2 TransportCatalysis33 ACTIVATION TransportCatalysis32 ACTIVATION 7732-18-5 CAS Sodium/potassium-transporting ATPase subunit alpha-1 Sodium-coupled neutral amino acid transporter 4 CHEBI:16199 ChEBI L-Amino acid Sodium/potassium-transporting ATPase subunit alpha-3 Large Neutral Amino Acids TransportCatalysis31 ACTIVATION Solute carrier family 12 member 1 TransportCatalysis30 ACTIVATION 791 ChemSpider Q969I6 UniProt Active Mineralocorticoid receptor Water Water Amiloride-sensitive sodium channel subunit alpha Solute carrier family 22 member 2 B(0,+)-type amino acid transporter 1 Epithelial Sodium Channel SubPathwayOutput BiologicalState14 Homo sapiens, Cell Membrane Neutral and basic amino acid transport protein rBAT Organic Cation P82251 UniProt Large neutral amino acids transporter small subunit 1 306 ChemSpider Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit beta-1 Organic Anion TransportCatalysis47 ACTIVATION Mineralocorticoid receptor Amiloride-sensitive sodium channel subunit gamma 1.0 Sodium/potassium-transporting ATPase subunit beta-3 Q9UHI5 UniProt Q15849 UniProt 1.0 TransportCatalysis188 ACTIVATION 52-39-1 CAS 962 PubChem-compound 9606 TAXONOMY CHEBI:17544 ChEBI O15244 UniProt Sodium 1.0 HMDB00294 HMDB 1176 PubChem-compound Amiloride-sensitive sodium channel subunit beta HMDB02111 HMDB Organic Cation TransportCatalysis51 ACTIVATION TransportCatalysis50 ACTIVATION 2.0 Hydrogen carbonate Amiloride-sensitive sodium channel subunit gamma CHEBI:15377 ChEBI L-Cysteine Cell Membrane Q9UM01 UniProt Sodium/potassium-transporting ATPase subunit alpha-2 Q9UHW9 UniProt TransportCatalysis68 ACTIVATION C00086 KEGG Compound 1.0 Chloride ion http://identifiers.org/smpdb/SMP00197 SMPDB CHEBI:27584 ChEBI CPD-4521 BioCyc ATPase, (Na+)/K+ transporting, beta 4 polypeptide C3H7NO2S L-Cysteine 121.01975 HMDB00037 HMDB L-Amino acid Chloride channel protein ClC-Ka C00097 KEGG Compound TransportCatalysis71 ACTIVATION H2O Water 18.010565 TransportCatalysis73 ACTIVATION TransportCatalysis72 ACTIVATION P50993 UniProt P51168 UniProt Sodium/potassium-transporting ATPase subunit beta-2 Nucleus P51172 UniProt Transport101 false Imino acids (→), Sodium (→), Chloride ion (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT P51170 UniProt Na Sodium 22.989769 Sodium/potassium-transporting ATPase subunit alpha-2 K Potassium 38.963707 Large neutral amino acids transporter small subunit 2 Sodium/potassium-transporting ATPase subunit alpha-4 Solute carrier family 12 member 1 Organic Cation 749 ChemSpider 2.0 71-52-3 CAS 1.0 1.0 1.0 Aquaporin-1 Sodium/potassium-transporting ATPase subunit gamma Transport107 false Hydrogen carbonate (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Mineralocorticoid receptor Transport106 false Urea (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Q9NP91 UniProt CHO3 Hydrogen carbonate 60.99257 Transport108 false Hydrogen carbonate (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport103 false L-Amino acid (→), Sodium (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT Transport105 false Urea (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 2.0 Transport104 false L-Amino acid (→), Sodium (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Extracellular Space LEFT_TO_RIGHT SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 SLC12A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 CLCNKA AQP1 AQP1 SLC12A1 CLCNKA SLC22A6 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 SLC12A6 SLC22A2 AQP2 AQP3 SCNN1A SCNN1B SCNN1D SCNN1G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 Unknown FXYD2 SLC1A1 SLC7A8 SLC3A2 SLC7A5 SLC3A2 SLC6A20 SLC38A4 SLC7A7 SLC3A2 SLC7A6 SLC3A2 SLC3A1 SLC7A9 SLC14A2 SLC14A2 NR3C2 Chloride ion Chloride ion Sodium Sodium Sodium Potassium Potassium Chloride ion Chloride ion Water Water Water Sodium Sodium Potassium Potassium Chloride ion Chloride ion Chloride ion Chloride ion Sodium Potassium Potassium Chloride ion Chloride ion Potassium Potassium Water Water Water Water Sodium Sodium Sodium Sodium Potassium Potassium Sodium Sodium Sodium Sodium Chloride ion Chloride ion Sodium Sodium Sodium Sodium Sodium Sodium Urea Urea Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate Hydrogen carbonate L-Cysteine L-Cysteine Urea Aldosterone Organic Anion Organic Anion Organic Cation Organic Cation L-Amino acid L-Amino acid Large Neutral Amino Acids Large Neutral Amino Acids Large Neutral Amino Acids Large Neutral Amino Acids Imino acids Imino acids L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid L-Amino acid Transcription/Translation