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Glycerol-3- phosphate dehydrogenase [NAD(+)], cytoplasmic glycerol-3- phosphate acyltransferase 1-acyl-sn- glycerol-3- phosphate acyltransferase phosphatidate phosphatase diacylglycerol O- acyltransferase Dihydroxyacetone phosphate NADH H + NAD Glycerol 3-phosphate Docosanoyl-CoA CoA LPA(22:0/0:0) LPA(22:0/0:0) Linoleoyl-CoA CoA PA(22:0/18:2(9Z,12Z)) H 2 O DG(22:0/18:2(9Z,12Z)/0:0) P i Stearidonoyl- CoA TG(22:0/18:2(9Z,12Z)/18:4(6Z,9Z,12Z,15Z)) CoA Glycolysis Mitochondria Outer Membrane Endoplasmic Reticulum Membrane Cytosol
Mitochondria Endoplasmic Reticulum GPD1 GPAM AGPAT1 LPIN1 DGAT1 Dihydroxyacetone phosphate NADH Hydrogen Ion NAD Glycerol 3-phosphate Docosanoyl-CoA Coenzyme A LPA(22:0/0:0) LPA(22:0/0:0) Linoleoyl-CoA Coenzyme A PA(22:0/18:2(9Z,12Z)) Water DG(22:0/18:2(9Z,12Z)/0:0) Phosphate Stearidonoyl- CoA TG(22:0/18:2(9Z,12Z)/18:4(6Z,9Z,12Z,15Z)) Coenzyme A Glycolysis