GRB2 GAB2 SOS1 CRKL CBL STAT5A JAK2 SKP2 CDKN1B MTOR RPS6KB1 BAD BCL2L1 MDM2 TP53 MYC BCR-ABL1 CRK PIK3R1 Dasatinib Ras Akt RAF MEK MAPK FOXO Nucleus Outer Membrane Nucleus Inner Membrane Transcription Proliferation and Survival Survival Protein Synthesis PI3K/Akt Pathway MAPK/ERK Pathway Proliferation Cytosol JAK-STAT Pathway Created with Snap
Nucleus GRB2 GAB2 SOS1 CRKL CBL STAT5A JAK2 SKP2 CDKN1B MTOR RPS6KB1 BAD BCL2L1 MDM2 TP53 MYC BCR-ABL1 CRK PIK3R1 Dasatinib Ras Akt RAF MEK MAPK FOXO Created with Snap
GRB2 GAB2 SOS1 CRKL CBL STAT5A JAK2 SKP2 CDKN1B MTOR RPS6KB1 BAD BCL2L1 MDM2 TP53 MYC BCR- ABL1 CRK PIK3R1 Dasatin Ras Akt RAF MEK MAPK FOXO Nucleus Outer Membrane Nucleus Inner Membrane Transcription Proliferation and Survival Survival Protein Synthesis PI3K/Akt Pathway MAPK/ERK Pathway Proliferation Cytosol JAK-STAT Pathway Created with Snap
Nucleus GRB2 GAB2 SOS1 CRKL CBL STAT5A JAK2 SKP2 CDKN1B MTOR RPS6KB1 BAD BCL2L1 MDM2 TP53 MYC BCR- ABL1 CRK PIK3R1 Dasatin Ras Akt RAF MEK MAPK FOXO Created with Snap