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HMDB01586 HMDB 6022 PubChem-compound http://identifiers.org/smpdb/SMP00027 SMPDB Mitochondrial pyruvate carrier 1 937 ChemSpider 96860 ChemSpider HMDB01341 HMDB 1.0 Glucose-6-phosphatase 439278 PubChem-compound 439153 PubChem-compound Phosphoglycerate mutase 2 Phosphoglycerate mutase 1 Bisphosphoglycerate mutase ReactionCatalysis942 ACTIVATION 50 ChemSpider ReactionCatalysis940 ACTIVATION 58238 ChemSpider HMDB01112 HMDB PW000055 PathWhiz C6H14O12P2 Fructose 1,6-bisphosphate 339.99606 PW000054 PathWhiz http://identifiers.org/smpdb/SMP00039 SMPDB OXALACETIC_ACID BioCyc ATP BioCyc HMDB00263 HMDB HMDB01473 HMDB Reaction1242 false 2,3-Diphosphoglyceric acid + Water ↔ 3-Phosphoglyceric acid + Phosphate REVERSIBLE Reaction1243 false 2,3-Diphosphoglyceric acid + Water ↔ 3-Phosphoglyceric acid + Phosphate REVERSIBLE Reaction1240 false Glyceric acid 1,3-biphosphate ↔ 2,3-Diphosphoglyceric acid REVERSIBLE ReactionCatalysis939 ACTIVATION ReactionCatalysis937 ACTIVATION Oxoglutaric acid Reaction1246 false 3-Phosphoglyceric acid ↔ 2-Phospho-D-glyceric acid REVERSIBLE http://identifiers.org/smpdb/SMP00031 SMPDB HMDB01201 HMDB HMDB00595 HMDB Malic acid 5743 ChemSpider 1.0 HCO3 BioCyc 5742 ChemSpider NADH PW000042 PathWhiz 2280-44-6 CAS ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc HMDB59597 HMDB 1.0 ReactionCatalysis965 ACTIVATION SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O Malate dehydrogenase, mitochondrial http://identifiers.org/smpdb/SMP00043 SMPDB HMDB00122 HMDB ReactionCatalysis960 ACTIVATION HMDB00243 HMDB HMDB00124 HMDB C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 PW000032 PathWhiz PW000159 PathWhiz 709 ChemSpider PW000036 PathWhiz C00221 KEGG Compound 2,3-Diphosphoglyceric acid 704 ChemSpider 1.0 945 ChemSpider PW000031 PathWhiz C00103 KEGG Compound 1010 ChemSpider PW000150 PathWhiz C10H15N5O11P2 Guanosine diphosphate 443.02432 O43826 UniProt 439165 PubChem-compound 488-69-7 CAS ReactionCatalysis958 ACTIVATION ReactionCatalysis713 ACTIVATION ReactionCatalysis955 ACTIVATION http://identifiers.org/smpdb/SMP00058 SMPDB ReactionCatalysis954 ACTIVATION 2.0 ReactionCatalysis952 ACTIVATION 1.0 http://identifiers.org/smpdb/SMP00055 SMPDB C3H7O6P D-Glyceraldehyde 3-phosphate 169.99803 138-08-9 CAS 1.0 C10H16N5O14P3 Guanosine triphosphate 522.99066 59-56-3 CAS C3H8O10P2 Glyceric acid 1,3-biphosphate 265.95926 Transport68 false Glucose 6-phosphate (←) Transport: Homo sapiens, Cell, Endoplasmic Reticulum to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT C00111 KEGG Compound Transport67 false Phosphate (→) Transport: Homo sapiens, Cell, Endoplasmic Reticulum to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Cytosol Alpha-enolase Q02978 UniProt C00236 KEGG Compound 388311 ChemSpider 1.0 C00597 KEGG Compound C00354 KEGG Compound P60174 UniProt Transport70 false Phosphoenolpyruvic acid (?) Transport: Homo sapiens, Cell, Mitochondrial Matrix to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Aldose 1-epimerase Glyceraldehyde-3-phosphate dehydrogenase Starch and Sucrose Metabolism SubPathway 7664-38-2 CAS 1.0 HMDB00208 HMDB Fructose 1,6-bisphosphate 1.0 Galactose Metabolism SubPathway false Fructose 6-phosphate ↔ Glucose 6-phosphate REVERSIBLE false Alpha-D-Glucose ↔ Beta-D-Glucose REVERSIBLE C00009 KEGG Compound C00008 KEGG Compound SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O HMDB00223 HMDB 1.0 C3H8O10P2 2,3-Diphosphoglyceric acid 265.95926 Hydrogen Ion C00001 KEGG Compound P15259 UniProt Fructose 6-phosphate SubPathwayInput SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 CHEBI:18367 ChEBI C00004 KEGG Compound Pyruvic acid SubPathwayOutput 1032 ChemSpider C00003 KEGG Compound 1.0 C00002 KEGG Compound 1031 ChemSpider Mitochondrial 2-oxoglutarate/malate carrier protein GLC-1-P BioCyc C6H12O6 Alpha-D-Glucose 180.06339 HMDB01429 HMDB Phosphate HMDB01401 HMDB 388411 ChemSpider 388538 ChemSpider Pyruvic acid SubPathwayOutput C21H28N7O14P2 NAD 664.11694 http://identifiers.org/smpdb/SMP00006 SMPDB 107689 PubChem-compound 2.0 http://identifiers.org/smpdb/SMP00008 SMPDB C00011 KEGG Compound 161681 ChemSpider FRUCTOSE-6P BioCyc Glucose-6-phosphatase CHEBI:17138 ChEBI H Hydrogen Ion 1.007825 1.0 http://identifiers.org/smpdb/SMP00016 SMPDB P52789 UniProt C00022 KEGG Compound 56-65-5 CAS P18669 UniProt Pyruvate carboxylase, mitochondrial 53-84-9 CAS C00026 KEGG Compound C00267 KEGG Compound 62713 ChemSpider CHEBI:26078 ChEBI 1.0 ReactionCatalysis513 ACTIVATION http://identifiers.org/smpdb/SMP00010 SMPDB http://identifiers.org/smpdb/SMP00374 SMPDB P06733 UniProt 769 PubChem-compound 525 PubChem-compound CL:0000000 CELL TYPE ONTOLOGY C00031 KEGG Compound 186004 PubChem-compound C00036 KEGG Compound Transport1 false Pyruvic acid (→) Transport: Homo sapiens, Cell, Cytosol to Homo sapiens, Cell, Mitochondrial Matrix LEFT_TO_RIGHT C00035 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 328-50-7 CAS L-Lactic acid SubPathwayOutput Oxalacetic acid D-Glucose SubPathwayOutput SubPathwayInput Adenosine diphosphate 492-61-5 CAS 4.0 false Glucose 1-phosphate + Water → D-Glucose + Phosphate LEFT_TO_RIGHT false Fructose 1,6-bisphosphate + Water → Fructose 6-phosphate + Phosphate LEFT_TO_RIGHT P06744 UniProt C00044 KEGG Compound 648 ChemSpider false Fructose 1,6-bisphosphate ↔ D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate REVERSIBLE false Glucose 6-phosphate + Water ↔ D-Glucose + Phosphate REVERSIBLE C00288 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O PHOSPHO-ENOL-PYRUVATE BioCyc HMDB00538 HMDB 4.0 SMILES OC(=O)C(=C)OP(O)(O)=O 64689 PubChem-compound Reaction812 false D-Glyceraldehyde 3-phosphate + NAD + Phosphoric acid ↔ Glyceric acid 1,3-biphosphate + NADH REVERSIBLE 1.0 C3H7O7P 3-Phosphoglyceric acid 185.99294 false Dihydroxyacetone phosphate ↔ D-Glyceraldehyde 3-phosphate REVERSIBLE 668 PubChem-compound Hexokinase-2 SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS CHEBI:16077 ChEBI CHEBI:4170 ChEBI 591-59-3 CAS NAD SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O Pyruvic acid 1.0 492-62-6 CAS 1.0 SubPathwayInteraction202 SubPathwayReaction SubPathway202Reaction NAD SubPathwayInteraction203 SubPathway203Reaction SubPathwayReaction SubPathwayInteraction200 SubPathway200Reaction SubPathwayReaction false Glucose 1-phosphate ↔ Glucose 6-phosphate REVERSIBLE Malic acid SubPathwayInteraction201 SubPathwayReaction SubPathway201Reaction C10H16N5O13P3 Adenosine triphosphate 506.99576 SubPathwayInteraction206 SubPathway206Reaction SubPathwayReaction Phosphoric acid DPG BioCyc SubPathwayInteraction207 SubPathwayReaction SubPathway207Reaction DIHYDROXY-ACETONE-PHOSPHATE BioCyc MAL BioCyc SubPathwayInteraction204 SubPathwayReaction SubPathway204Reaction SubPathwayInteraction205 SubPathwayReaction SubPathway205Reaction C00186 KEGG Compound SubPathwayInteraction208 SubPathway208Reaction SubPathwayReaction SubPathwayInteraction209 SubPathway209Reaction SubPathwayReaction C01159 KEGG Compound 445557 PubChem-compound SMILES CC(=O)C(O)=O 663 ChemSpider Alpha-D-Glucose C3H7O7P 2-Phospho-D-glyceric acid 185.99294 C00074 KEGG Compound CHEBI:17050 ChEBI Mitochondrial pyruvate carrier 1 false Adenosine triphosphate + Hydrogen carbonate + Pyruvic acid → Adenosine diphosphate + Oxalacetic acid + Phosphate LEFT_TO_RIGHT SMILES OCC(=O)COP(O)(O)=O Tyrosine Metabolism SubPathway HMDB00516 HMDB HMDB01967 HMDB Glycerolipid Metabolism SubPathway 3-Phosphoglyceric acid SubPathwayInput Propanoate Metabolism SubPathway P07738 UniProt 962 PubChem-compound 724 PubChem-compound P11168 UniProt 5800 ChemSpider Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Malate dehydrogenase, mitochondrial Fructose-bisphosphate aldolase A Fructose-1,6-bisphosphatase 1 979 ChemSpider CO2 Carbon dioxide 43.98983 C00080 KEGG Compound C00085 KEGG Compound H3O4P Phosphoric acid 97.9769 C01172 KEGG Compound 2.0 729 PubChem-compound Phosphoglycerate mutase 1 Q9Y5U8 UniProt BiologicalState3 Homo sapiens, Cell, Mitochondrion C4H6O5 Malic acid 134.02153 BiologicalState2 Homo sapiens, Cell, Cytosol 14265-44-2 CAS CHEBI:44897 ChEBI Glucose-6-phosphate isomerase PYRUVATE BioCyc HMDB00744 HMDB 58-64-0 CAS C6H13O9P Glucose 1-phosphate 260.02972 GTP BioCyc C00092 KEGG Compound 71358 ChemSpider G3P BioCyc Glucose-6-phosphate isomerase CHEBI:4167 ChEBI Oxalacetic acid C3H6O3 L-Lactic acid 90.03169 P04406 UniProt 1.0 56-73-5 CAS 2-PG BioCyc 1.0 23-DIPHOSPHOGLYCERATE BioCyc SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Phosphoglucomutase-1 1.0 Pantothenate kinase 1 Malate dehydrogenase, mitochondrial 510 ChemSpider H2O Water 18.010565 138-81-8 CAS SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O 1.0 393165 ChemSpider Triosephosphate isomerase NADH BioCyc 1.0 Glucose 6-phosphate Beta-D-Glucose NAD BioCyc 1.0 Glucose-6-phosphate translocase Malic acid 1.0 Glyceraldehyde-3-phosphate dehydrogenase 749 ChemSpider 71-52-3 CAS 1.0 970 PubChem-compound 4.0 980 ChemSpider 1.0 146-91-8 CAS CHO3 Hydrogen carbonate 60.99257 CHEBI:15903 ChEBI Aldose 1-epimerase 820-11-1 CAS 2-Phospho-D-glyceric acid 1.0 Pantothenate and CoA Biosynthesis SubPathway Nucleotide Sugars Metabolism SubPathway C4H4O5 Oxalacetic acid 132.00587 Thiamine Metabolism SubPathway 4.0 CHEBI:6650 ChEBI Glyceraldehyde-3-phosphate dehydrogenase 1.0 1.0 SMILES O P35575 UniProt Q96C23 UniProt C6H12O6 Beta-D-Glucose 180.06339 1.0 HMDB00807 HMDB Triosephosphate isomerase P11498 UniProt Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Fructose and Mannose Degradation SubPathway 1004 PubChem-compound 1005 PubChem-compound TransportCatalysis6 ACTIVATION TransportCatalysis8 ACTIVATION 643-13-0 CAS 1981-49-3 CAS 328-42-7 CAS C3H7O6P Dihydroxyacetone phosphate 169.99803 51 PubChem-compound SMILES OC([O-])=O CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 1038 PubChem-compound Pantothenate kinase 1 GO:0005829 GENE ONTOLOGY 274 ChemSpider C5H6O5 Oxoglutaric acid 146.02153 Hydrogen Ion CHEBI:16905 ChEBI HMDB00902 HMDB Fructose-1,6-bisphosphatase 1 Guanosine triphosphate CHEBI:16908 ChEBI Guanosine diphosphate O4P Phosphate 94.95342 6830 PubChem-compound 1.0 Adenosine triphosphate CHEBI:15946 ChEBI L-LACTATE BioCyc Mitochondrion P40926 UniProt Hexokinase-2 Solute carrier family 2, facilitated glucose transporter member 2 Glucose 1-phosphate SubPathwayOutput Carbon dioxide 683 PubChem-compound Phosphoenolpyruvic acid SubPathwayInput Triosephosphate isomerase 58-68-4 CAS SMILES [O-]P([O-])([O-])=O Pantothenate kinase 1 SMILES OC(=O)CCC(=O)C(O)=O 1.0 C6H13O9P Fructose 6-phosphate 260.02972 124-38-9 CAS CHEBI:30915 ChEBI C6H12O6 D-Glucose 180.06339 2.0 Fructose-bisphosphate aldolase A CHEBI:17835 ChEBI Phosphoenolpyruvic acid ReactionCatalysis4 ACTIVATION GLC BioCyc 1.0 1.0 Malate dehydrogenase, mitochondrial GO:0005758 GENE ONTOLOGY GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc GO:0005759 GENE ONTOLOGY 1.0 57-04-5 CAS 69507 PubChem-compound Pyruvate carboxylase, mitochondrial P35558 UniProt 1.0 SMILES O=C=O 1.0 Malate dehydrogenase, mitochondrial SubPathwayInteraction814 SubPathway814Reaction SubPathwayReaction SMILES OP(O)(O)=O SMILES OC(CC(O)=O)C(O)=O 5958 PubChem-compound C21H29N7O14P2 NADH 665.12476 D-Glucose 5957 PubChem-compound Malic acid P00338 UniProt CHEBI:15996 ChEBI SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O L-lactate dehydrogenase A chain Alpha-enolase 1.0 C3H5O6P Phosphoenolpyruvic acid 167.98238 1.0 Adenosine triphosphate GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 HMDB03391 HMDB SMILES C[C@H](O)C(O)=O P36871 UniProt D-Glyceraldehyde 3-phosphate SubPathwayOutput SubPathwayInput CHEBI:17925 ChEBI C00711 KEGG Compound Endoplasmic Reticulum 1.0 L-lactate dehydrogenase A chain CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O TransportCatalysis15 ACTIVATION 5682 ChemSpider Dihydroxyacetone phosphate Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease Mitochondrial Matrix C6H13O9P Glucose 6-phosphate 260.02972 2.0 ReactionCatalysis661 ACTIVATION Phosphoglucomutase-1 HMDB03498 HMDB Phosphoglycerate mutase 2 Pyruvate carboxylase, mitochondrial Mitochondrial 2-oxoglutarate/malate carrier protein Adenosine diphosphate SMILES OC(COP(O)(O)=O)C(=O)OP(O)(O)=O Q8TE04 UniProt 6915-15-7 CAS ReactionCatalysis658 ACTIVATION PW000205 PathWhiz ReactionCatalysis1053 ACTIVATION false 2-Phospho-D-glyceric acid ↔ Phosphoenolpyruvic acid + Water REVERSIBLE Cell 439427 PubChem-compound HMDB03345 HMDB 1.0 CHEBI:15422 ChEBI CHEBI:17720 ChEBI 5589 ChemSpider P09467 UniProt Glucose-6-phosphate translocase TransportCatalysis34 ACTIVATION Hydrogen carbonate Beta-D-Glucose 6-phosphate Transport42 false D-Glucose (→) Transport: Homo sapiens, Liver, Hepatocyte, Cytosol to Homo sapiens, Blood Vessel LEFT_TO_RIGHT 388299 ChemSpider 1.0 1.0 79-33-4 CAS 127-17-3 CAS Fructose-1,6-bisphosphatase 1 HMDB00190 HMDB CHEBI:17719 ChEBI GO:0005783 GENE ONTOLOGY Water false L-Lactic acid + NAD ↔ Hydrogen Ion + NADH + Pyruvic acid REVERSIBLE HMDB01058 HMDB FRUCTOSE-16-DIPHOSPHATE BioCyc 1.0 CHEBI:16526 ChEBI SMILES O[C@H]1[C@H](O)[C@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O HMDB01294 HMDB 8977 PubChem-compound HMDB02142 HMDB CHEBI:16761 ChEBI Transport32 false Oxoglutaric acid (←), Malic acid (→) Transport: Homo sapiens, Cell, Mitochondrial Matrix to Homo sapiens, Cell, Mitochondrial Intermembrane Space LEFT_TO_RIGHT GLC-6-P BioCyc false Malic acid + NAD ↔ Hydrogen Ion + NADH + Oxalacetic acid REVERSIBLE 1.0 NADH 1.0 9606 TAXONOMY PW000144 PathWhiz P04075 UniProt Glucose 6-phosphate CHEBI:17544 ChEBI PW000142 PathWhiz PW000149 PathWhiz 2-KETOGLUTARATE BioCyc PW000025 PathWhiz SMILES OC(COP(O)(O)=O)C(O)=O Oxoglutaric acid C00631 KEGG Compound 8630 ChemSpider 5893 PubChem-compound HMDB02111 HMDB http://identifiers.org/smpdb/SMP00060 SMPDB SubPathwayInteraction190 SubPathway190Reaction SubPathwayReaction false 3-Phosphoglyceric acid + Adenosine triphosphate → Adenosine diphosphate + Glyceric acid 1,3-biphosphate LEFT_TO_RIGHT SubPathwayInteraction194 SubPathway194Reaction SubPathwayReaction http://identifiers.org/smpdb/SMP00067 SMPDB SubPathwayInteraction195 SubPathway195Reaction SubPathwayReaction Fructose-bisphosphate aldolase A false Adenosine triphosphate + Beta-D-Glucose → Adenosine diphosphate + Beta-D-Glucose 6-phosphate LEFT_TO_RIGHT Mitochondrial Intermembrane Space SubPathwayInteraction193 SubPathwayReaction SubPathway193Reaction CHEBI:32816 ChEBI SubPathwayInteraction198 SubPathway198Reaction SubPathwayReaction ReactionCatalysis349 ACTIVATION http://identifiers.org/smpdb/SMP00064 SMPDB SubPathwayInteraction199 SubPathwayReaction SubPathway199Reaction SubPathwayInteraction196 SubPathwayReaction SubPathway196Reaction ReactionCatalysis347 ACTIVATION SubPathwayInteraction197 SubPathway197Reaction SubPathwayReaction CHEBI:15377 ChEBI ReactionCatalysis344 ACTIVATION ReactionCatalysis343 ACTIVATION CHEBI:15378 ChEBI SMILES [H+] Glucose-6-phosphate isomerase CHEBI:16108 ChEBI 6569 ChemSpider HMDB01270 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Glyceric acid 1,3-biphosphate CHEBI:17552 ChEBI HMDB01273 HMDB Phosphate SMILES OC[C@@H](OP(O)(O)=O)C(O)=O CHEBI:422 ChEBI 280 PubChem-compound CHEBI:30744 ChEBI 79025 PubChem-compound Phosphate http://identifiers.org/smpdb/SMP00076 SMPDB false Guanosine triphosphate + Oxalacetic acid ↔ Carbon dioxide + Guanosine diphosphate + Phosphoenolpyruvic acid REVERSIBLE HMDB01487 HMDB PW000002 PathWhiz 5793 PubChem-compound PW000001 PathWhiz ReactionCatalysis375 ACTIVATION ReactionCatalysis373 ACTIVATION Pyruvate Metabolism SubPathway SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 1.0 Pentose Phosphate Pathway SubPathway 1.0 SMILES OC(COP(O)(O)=O)C=O false Adenosine triphosphate + Alpha-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate LEFT_TO_RIGHT Aspartate Metabolism SubPathway Alanine Metabolism SubPathway 86-01-1 CAS false Beta-D-Glucose 6-phosphate ↔ Fructose 6-phosphate REVERSIBLE GAP BioCyc 1060 PubChem-compound 1061 PubChem-compound 2.0 Bisphosphoglycerate mutase Phenylalanine and Tyrosine Metabolism SubPathway C00661 KEGG Compound SMILES OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O 1.0 Solute carrier family 2, facilitated glucose transporter member 2 Bisphosphoglycerate mutase SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Glucose-6- phosphate translocase Mitochondrial 2- oxoglutarate/malate carrier protein Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 1 Glucose-6- phosphatase Glucose-6- phosphatase Phosphoglucomutase- 1 Glucose-6- phosphate isomerase Hexokinase-2 Aldose 1-epimerase Hexokinase-2 Glucose-6- phosphate isomerase Fructose-1,6- bisphosphatase 1 Fructose- bisphosphate aldolase A Triosephosphate isomerase Glyceraldehyde- 3-phosphate dehydrogenase Pantothenate kinase 1 Phosphoglycerate mutase 2 Alpha-enolase Bisphosphoglycerate mutase Bisphosphoglycerate mutase Phosphoglycerate mutase 1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Malate dehydrogenase, mitochondrial Malate dehydrogenase, mitochondrial Pyruvate carboxylase, mitochondrial Phosphoenolpyruvate carboxykinase, cytosolic [GTP] L-lactate dehydrogenase A-like 6A Pyruvate carboxylase, mitochondrial Dissipation D-Glucose Glucose 1-phosphate D-Glyceraldehyde 3-phosphate Fructose 6-phosphate Phosphoenolpyruvic acid Pyruvic acid Accumulation L-Lactic acid 3-Phosphoglyceric acid Pyruvic acid Dissipation D-Glucose Dissipation D-Glucose P i P i Glucose 6-phosphate Glucose 6-phosphate Oxoglutaric acid Oxoglutaric acid Malic acid Malic acid Phosphoenolpyruvic acid Pyruvic acid Pyruvic acid H 2 O H 2 O P i Alpha-D-Glucose ATP ADP Beta-D-Glucose ATP ADP Beta-D-Glucose 6-phosphate Fructose 1,6-bisphosphate H 2 O P i Dihydroxyacetone phosphate NAD P i Glyceric acid 1,3-biphosphate NADH ATP ADP 2-Phospho-D-glyceric acid H 2 O 2,3-Diphosphoglyceric acid H 2 O P i H 2 O P i GTP Oxalacetic acid GDP CO 2 NAD NADH H + NAD Oxalacetic acid NADH H + ATP Hydrogen carbonate ADP P i GTP Oxalacetic acid GDP CO 2 NAD NADH H + ATP Hydrogen carbonate ADP P i Magnesium Magnesium Magnesium Manganese Biotin Manganese Manganese Biotin Manganese Galactose Metabolism Nucleotide Sugars Metabolism Starch and Sucrose Metabolism Pentose Phosphate Pathway Fructose and Mannose Degradation Galactose Metabolism Thiamine Metabolism Phenylalanine and Tyrosine Metabolism Pyruvate Metabolism Pantothenate and CoA Biosynthesis Aspartate Metabolism Tyrosine Metabolism Propanoate Metabolism Glycerolipid Metabolism Alanine Metabolism Pyruvate Metabolism