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C23H38N7O17P3S Acetyl-CoA 809.1258 17220838 ChemSpider C00318 KEGG Compound 937 ChemSpider HMDB00250 HMDB 388353 ChemSpider (2E)-Decenoyl-CoA 439153 PubChem-compound L-Carnitine 1.0 Trifunctional enzyme subunit alpha, mitochondrial SMP00025 SMPDB Enoyl-CoA hydratase, mitochondrial 1.0 Trifunctional enzyme subunit beta, mitochondrial C33H58N7O17P3S Lauroyl-CoA 949.2823 CHEBI:16027 ChEBI 38795-33-4 CAS Hexanoyl-CoA SMP00039 SMPDB ATP BioCyc 1.0 Reduced electron-transfer flavoprotein P45954 UniProt 559142 ChemSpider 1.0 1.0 Tetradecanoyl-CoA PW000048 PathWhiz HMDB01206 HMDB 5742 ChemSpider CPD-196 BioCyc C02990 KEGG Compound C00332 KEGG Compound 11966197 PubChem-compound Trifunctional enzyme, mitochondrial 440045 PubChem-compound HMDB59597 HMDB 1.0 5858 ChemSpider 2364-67-2 CAS Carbon dioxide HMDB01339 HMDB HMDB01338 HMDB 7-METHYL-3-OXOOCTANOYL-COA BioCyc 4.0 Reduced electron-transfer flavoprotein 1010 ChemSpider Enoyl-CoA hydratase, mitochondrial SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS PPI BioCyc (2E)-Octenoyl-CoA Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial SMP00054 SMPDB HMDB01423 HMDB C27H46N7O17P3S Hexanoyl-CoA 865.18835 P16219 UniProt CHEBI:5086 ChEBI Medium-chain specific acyl-CoA dehydrogenase, mitochondrial LAUROYLCOA-CPD BioCyc Short-chain specific acyl-CoA dehydrogenase, mitochondrial Lauroyl-CoA Long-chain-fatty-acid--CoA ligase 1 53477508 PubChem-compound HMDB00222 HMDB C00249 KEGG Compound 3-ketoacyl-CoA thiolase, mitochondrial C00001 KEGG Compound 1.0 SubPathwayInteraction80 SubPathway80Reaction SubPathwayReaction CHEBI:18361 ChEBI NADH C00004 KEGG Compound C00003 KEGG Compound HMDB00220 HMDB C00002 KEGG Compound Acetyl-CoA acetyltransferase, mitochondrial 103192-48-9 CAS L-Palmitoylcarnitine P42765 UniProt Coenzyme A Mitochondrial Inner Membrane SubPathwayInteraction79 SubPathwayReaction SubPathway79Reaction L-Carnitine CHEBI:28276 ChEBI 3130-72-1 CAS HMDB03941 HMDB 389502 ChemSpider HMDB03942 HMDB 389501 ChemSpider C29H50N7O17P3S Octanoyl-CoA 893.21967 HMDB01521 HMDB 389500 ChemSpider HMDB03940 HMDB SMILES C[C@@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N HMDB03945 HMDB 389507 ChemSpider C21H28N7O14P2 NAD 664.11694 HMDB03946 HMDB 389506 ChemSpider 1.0 HMDB03943 HMDB 389504 ChemSpider HMDB03944 HMDB C00011 KEGG Compound C00010 KEGG Compound C00136 KEGG Compound C00013 KEGG Compound CHEBI:10723 ChEBI HMDB03938 HMDB HMDB03939 HMDB HMDB03936 HMDB 389509 ChemSpider HMDB03937 HMDB 389508 ChemSpider CHEBI:28264 ChEBI P28330 UniProt H Hydrogen Ion 1.007825 CARNITINE BioCyc C25H42N7O17P3S Butyryl-CoA 837.15704 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS 389510 ChemSpider Carnitine O-palmitoyltransferase 1 1.0 C00024 KEGG Compound (S)-Hydroxydecanoyl-CoA 1.3.8.7 false 1.3.8.7 Lauroyl-CoA + electron-transfer flavoprotein → (2E)-Tetradecenoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT 1264-57-9 CAS CHEBI:17490 ChEBI HMDB03949 HMDB CHEBI:28493 ChEBI HMDB03948 HMDB Adenosine monophosphate 4460-95-1 CAS 4.2.1.17 false 4.2.1.17 (S)-3-Hydroxydodecanoyl-CoA → (2E)-Tetradecenoyl-CoA + Water LEFT_TO_RIGHT 72059-49-5 CAS L-Palmitoylcarnitine BiologicalState22 3-Oxohexadecanoyl-CoA CL:0000000 CELL TYPE ONTOLOGY C00154 KEGG Compound C37H66N7O18P3S (S)-3-Hydroxyhexadecanoyl-CoA 1021.3398 C35H62N7O18P3S (S)-3-Hydroxytetradecanoyl-CoA 993.3085 Carnitine O-palmitoyltransferase 1, liver isoform C35H60N7O18P3S 3-Oxotetradecanoyl-CoA 991.29285 4.0 Carnitine O-palmitoyltransferase 2, mitochondrial Long-chain-fatty-acid--CoA ligase 1 SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O AMP BioCyc 2871-66-1 CAS SMILES CC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 35106-50-4 CAS Palmitic acid SMILES [O-]P([O-])(=O)OP([O-])([O-])=O HMDB03934 HMDB HMDB03935 HMDB HMDB03932 HMDB HMDB02845 HMDB 16061159 PubChem-compound 1.0 CPD-12174 BioCyc SMILES CCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 SMILES [H][C@](O)(CCCCC)CC(=O)SCCNC(=O)CCNC(=O)[C@]([H])(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H](C(O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N SMILES CCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCSC(=O)CCCC(O)=O SMILES CCCCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N C02593 KEGG Compound SMILES CCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 C03561 KEGG Compound C37H64N7O18P3S 3-Oxohexadecanoyl-CoA 1019.32416 SMILES CCCCCCCCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 SMILES CCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 1.0 (S)-Hydroxyoctanoyl-CoA C31H54N7O17P3S Decanoyl-CoA (n-C10:0CoA) 921.251 SMILES CCCCCCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H](C(O)[C@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 HMDB00538 HMDB 1.0 7732-18-5 CAS 54684-64-9 CAS 3-OXOPALMITOYL-COA BioCyc 61-19-8 CAS 2140-48-9 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 1.0 1.0 Acetoacetyl-CoA 1.0 57-10-3 CAS 3-Oxooctanoyl-CoA Q92947 UniProt 2.0 BiologicalState17 C10H16N5O13P3 Adenosine triphosphate 506.99576 165436 PubChem-compound NAD SMILES C[N+](C)(C)C[C@H](O)CC([O-])=O 1.0 HMDB01967 HMDB Adenosine triphosphate 962 PubChem-compound GLUTARYL-COA BioCyc Long-chain specific acyl-CoA dehydrogenase, mitochondrial trans-2-Hexenoyl-CoA CO2 Carbon dioxide 43.98983 C00080 KEGG Compound P50416 UniProt Water Long-chain specific acyl-CoA dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial 1.0 BiologicalState4 4.0 6245-70-1 CAS 6.0 1.0 1.0 1.0 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.0 1.0 1.0 6.0 960 ChemSpider 1.0 1.0 1.0 1264-52-4 CAS 985 PubChem-compound 644102 PubChem-compound 444493 PubChem-compound 6083 PubChem-compound Glutaryl-CoA dehydrogenase, mitochondrial 3-Oxododecanoyl-CoA SMILES CCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 SMILES CCC\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N SMILES CCCCCCCCCCCCC\C=C\C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(=O)([O-])[O-])N1C=NC2=C1N=CN=C2N ACETYL-COA BioCyc SMILES CCCCCCCCCCC\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N H2O Water 18.010565 SMILES CCCCCCC\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 4.0 Carnitine O-palmitoyltransferase 2, mitochondrial SMILES CCCCC\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N P55084 UniProt NADH BioCyc NAD BioCyc SMP00538 SMPDB Acetyl-CoA acetyltransferase, mitochondrial Acetyl-CoA 11953816 PubChem-compound SMILES CCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N ReactionCatalysis279 ACTIVATION Reaction759 false (S)-3-Hydroxydodecanoyl-CoA + NAD ↔ 3-Oxododecanoyl-CoA + Hydrogen Ion + NADH REVERSIBLE ReactionCatalysis276 ACTIVATION 2.3.1.16 false 2.3.1.16 Acetyl-CoA + Decanoyl-CoA (n-C10:0CoA) → 3-Oxododecanoyl-CoA + Coenzyme A LEFT_TO_RIGHT ReactionCatalysis275 ACTIVATION 65113 PubChem-compound (S)-3-Hydroxytetradecanoyl-CoA Reaction755 false (S)-Hydroxydecanoyl-CoA + NAD ↔ 3-Oxodecanoyl-CoA + Hydrogen Ion + NADH REVERSIBLE ReactionCatalysis272 ACTIVATION C23H45NO4 L-Palmitoylcarnitine 399.33487 78303-19-2 CAS 4.2.1.17 false 4.2.1.17 (S)-Hydroxydecanoyl-CoA ↔ (2E)-Decenoyl-CoA + Water REVERSIBLE ReactionCatalysis273 ACTIVATION ReactionCatalysis270 ACTIVATION 1.0 P49748 UniProt 3-Oxotetradecanoyl-CoA Coenzyme A 10140190 ChemSpider SMILES O Palmityl-CoA 2.3.1.16 false 2.3.1.16 Acetyl-CoA + Octanoyl-CoA ↔ 3-Oxodecanoyl-CoA + Coenzyme A REVERSIBLE 371 ChemSpider Reaction751 false (S)-Hydroxyoctanoyl-CoA + NAD ↔ 3-Oxooctanoyl-CoA + Hydrogen Ion + NADH REVERSIBLE 4.2.1.17 false 4.2.1.17 (S)-Hydroxyoctanoyl-CoA ↔ (2E)-Octenoyl-CoA + Water REVERSIBLE C10H14N5O7P Adenosine monophosphate 347.06308 CPD-419 BioCyc 2.3.1.16 false 2.3.1.16 Acetyl-CoA + Hexanoyl-CoA ↔ 3-Oxooctanoyl-CoA + Coenzyme A REVERSIBLE P40939 UniProt ReactionCatalysis267 ACTIVATION ReactionCatalysis268 ACTIVATION ReactionCatalysis265 ACTIVATION 4.2.1.17 false 4.2.1.17 (S)-3-Hydroxyhexadecanoyl-CoA ↔ (2E)-Hexadecenoyl-CoA + Water REVERSIBLE ReactionCatalysis263 ACTIVATION 2.3.1.16 false 2.3.1.16 Acetyl-CoA + Tetradecanoyl-CoA ↔ 3-Oxohexadecanoyl-CoA + Coenzyme A REVERSIBLE Reaction767 false (S)-3-Hydroxyhexadecanoyl-CoA + NAD ↔ 3-Oxohexadecanoyl-CoA + Hydrogen Ion + NADH REVERSIBLE ReactionCatalysis262 ACTIVATION CHEBI:57371 ChEBI Carnitine O-palmitoyltransferase 1, liver isoform ReactionCatalysis260 ACTIVATION 6816 PubChem-compound 5060-32-2 CAS 4.2.1.17 false 4.2.1.17 (S)-3-Hydroxytetradecanoyl-CoA ↔ (2E)-Tetradecenoyl-CoA + Water REVERSIBLE (S)-3-Hydroxyhexadecanoyl-CoA CHEBI:15846 ChEBI Very long-chain specific acyl-CoA dehydrogenase, mitochondrial 1.0 2.3.1.16 false 2.3.1.16 Acetyl-CoA + Lauroyl-CoA → 3-Oxotetradecanoyl-CoA + Coenzyme A LEFT_TO_RIGHT C7H15NO3 L-Carnitine 161.1052 Reaction763 false (S)-3-Hydroxytetradecanoyl-CoA + NAD ↔ 3-Oxotetradecanoyl-CoA + Hydrogen Ion + NADH REVERSIBLE 102680-35-3 CAS 1.0 PALMITYL-COA BioCyc ReactionCatalysis178 ACTIVATION 1.3.8.6 false 1.3.8.6 Glutaryl-CoA → Carbon dioxide + Crotonoyl-CoA LEFT_TO_RIGHT 440609 PubChem-compound ReactionCatalysis176 ACTIVATION ReactionCatalysis294 ACTIVATION 1.3.8.8 false 1.3.8.8 Octanoyl-CoA + electron-transfer flavoprotein → (2E)-Octenoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT 440608 PubChem-compound 1.3.8.8 false 1.3.8.8 Hexanoyl-CoA + electron-transfer flavoprotein → Reduced electron-transfer flavoprotein + trans-2-Hexenoyl-CoA LEFT_TO_RIGHT 1.0 SMILES CCCCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 440606 PubChem-compound ReactionCatalysis293 ACTIVATION SMILES CCCCCCCCCCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 ReactionCatalysis290 ACTIVATION 440604 PubChem-compound 380 PubChem-compound 5280381 PubChem-compound ReactionCatalysis291 ACTIVATION SMILES CCCCCCCCCCCCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 1038 PubChem-compound 440603 PubChem-compound 440602 PubChem-compound 265 PubChem-compound 440601 PubChem-compound 440600 PubChem-compound C25H40N7O17P3S Crotonoyl-CoA 835.1414 274 ChemSpider 1.3.8.9 false 1.3.8.9 Palmityl-CoA + electron-transfer flavoprotein → (2E)-Hexadecenoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT HMDB00902 HMDB 1.3.8.8 false 1.3.8.8 Tetradecanoyl-CoA + electron-transfer flavoprotein → (2E)-Tetradecenoyl-CoA + Reduced electron-transfer flavoprotein LEFT_TO_RIGHT 6.2.1.3 false 6.2.1.3 Adenosine triphosphate + Coenzyme A + Palmitic acid → Adenosine monophosphate + Palmityl-CoA + Pyrophosphate LEFT_TO_RIGHT Butyryl-CoA 2.3.1.21 false 2.3.1.21 L-Carnitine + Palmityl-CoA ↔ Coenzyme A + L-Palmitoylcarnitine REVERSIBLE CHEBI:16908 ChEBI ReactionCatalysis289 ACTIVATION K-HEXANOYL-COA BioCyc ReactionCatalysis288 ACTIVATION ReactionCatalysis285 ACTIVATION ReactionCatalysis283 ACTIVATION ReactionCatalysis284 ACTIVATION ReactionCatalysis281 ACTIVATION ReactionCatalysis280 ACTIVATION SMILES CCCCCCCCCCCCCC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 1.0 SMILES CCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Coenzyme A CHEBI:61526 ChEBI C16H32O2 Palmitic acid 256.24023 260 ChemSpider 1.0 Reaction780 false 3-Hydroxybutyryl-CoA + NAD ↔ Acetoacetyl-CoA + Hydrogen Ion + NADH REVERSIBLE CHEBI:15521 ChEBI CHEBI:15524 ChEBI CHEBI:15525 ChEBI 541-15-1 CAS C27H46N7O18P3S (S)-Hydroxyhexanoyl-CoA 881.1833 C27H44N7O18P3S 3-Oxohexanoyl-CoA 879.16766 C27H44N7O17P3S trans-2-Hexenoyl-CoA 863.1727 C37H60N7O17P3S (2E)-Hexadecenoyl-CoA 999.2979 1.0 Palmityl-CoA 4444072 ChemSpider 58-68-4 CAS C35H60N7O17P3S (2E)-Tetradecenoyl-CoA 975.2979 C31H52N7O17P3S (2E)-Decenoyl-CoA 919.23535 C29H48N7O17P3S (2E)-Octenoyl-CoA 891.20404 SMILES C\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 CHEBI:28726 ChEBI 124-38-9 CAS Pyrophosphate 1.0 P30084 UniProt CHEBI:15533 ChEBI CHEBI:15532 ChEBI 1.0 (2E)-Hexadecenoyl-CoA 3-Oxohexanoyl-CoA Acetyl-CoA acetyltransferase, mitochondrial 1.0 CHEBI:28706 ChEBI 440615 PubChem-compound 1763-10-6 CAS TETRADECANOYL-COA BioCyc CPD-1083 BioCyc C05259 KEGG Compound 440611 PubChem-compound C05258 KEGG Compound 440610 PubChem-compound C05264 KEGG Compound Short-chain specific acyl-CoA dehydrogenase, mitochondrial C05263 KEGG Compound C05266 KEGG Compound C05265 KEGG Compound SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C P23786 UniProt C05260 KEGG Compound 4.0 2.0 GO:0005759 GENE ONTOLOGY Octanoyl-CoA SMILES CCCCCCCCCCCCCCCC(O)=O C05262 KEGG Compound P24752 UniProt 4.0 C05261 KEGG Compound CHEBI:27868 ChEBI Carnitine palmitoyl transferase deficiency (I) 19774-86-8 CAS C35H62N7O17P3S Tetradecanoyl-CoA 977.3136 electron-transfer flavoprotein SubPathwayInteraction811 SubPathway811Reaction SubPathwayReaction Short-chain specific acyl-CoA dehydrogenase, mitochondrial SubPathwayInteraction810 SubPathwayReaction SubPathway810Reaction Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial SMILES O=C=O C05268 KEGG Compound Very long-chain specific acyl-CoA dehydrogenase, mitochondrial C05267 KEGG Compound Hydrogen Ion C05269 KEGG Compound HMDB01088 HMDB 1.0 C05275 KEGG Compound O7P2 Pyrophosphate 173.91193 C05274 KEGG Compound C25H40N7O18P3S Acetoacetyl-CoA 851.13635 C05276 KEGG Compound C21H29N7O14P2 NADH 665.12476 C05271 KEGG Compound C05270 KEGG Compound C05273 KEGG Compound 5957 PubChem-compound C05272 KEGG Compound GO:0005743 GENE ONTOLOGY PW000514 PathWhiz GO:0005741 GENE ONTOLOGY Decanoyl-CoA (n-C10:0CoA) 1.0 34619-89-1 CAS 1.0 4.2.1.17 false 4.2.1.17 (S)-Hydroxyhexanoyl-CoA ↔ Water + trans-2-Hexenoyl-CoA REVERSIBLE 1.0 2.3.1.16 false 2.3.1.16 Acetyl-CoA + Butyryl-CoA → 3-Oxohexanoyl-CoA + Coenzyme A LEFT_TO_RIGHT Reaction747 false (S)-Hydroxyhexanoyl-CoA + NAD ↔ 3-Oxohexanoyl-CoA + Hydrogen Ion + NADH REVERSIBLE CHEBI:15756 ChEBI Palmityl-CoA SubPathwayInteraction809 SubPathwayReaction SubPathway809Reaction L-Palmitoylcarnitine (2E)-Hexadecenoyl-CoA C37H66N7O17P3S Palmityl-CoA 1005.34485 C33H58N7O18P3S (S)-3-Hydroxydodecanoyl-CoA 965.27716 C26H42N7O19P3S Glutaryl-CoA 881.1469 CHEBI:27721 ChEBI C33H56N7O18P3S 3-Oxododecanoyl-CoA 963.26154 C31H54N7O18P3S (S)-Hydroxydecanoyl-CoA 937.2459 GO:0005737 GENE ONTOLOGY 1.0 C31H52N7O18P3S 3-Oxodecanoyl-CoA 935.2302 C29H50N7O18P3S (S)-Hydroxyoctanoyl-CoA 909.2146 C29H48N7O18P3S 3-Oxooctanoyl-CoA 907.1989 P33121 UniProt ReactionCatalysis311 ACTIVATION ReactionCatalysis312 ACTIVATION Mitochondrial Outer Membrane 58623 ChemSpider 10018-95-8 CAS electron-transfer flavoprotein SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 3-Oxodecanoyl-CoA 1.0 Transport21 false L-Palmitoylcarnitine (→) Transport: Homo sapiens, Cell, Cytoplasm to Homo sapiens, Cell, Mitochondrial Matrix LEFT_TO_RIGHT 5682 ChemSpider SMILES CCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 2-METHYL-3-HYDROXY-BUTYRYL-COA BioCyc Reduced electron-transfer flavoprotein 5280765 PubChem-compound CHEBI:1146900 ChEBI 4.0 CHEBI:28528 ChEBI ReactionCatalysis308 ACTIVATION ReactionCatalysis309 ACTIVATION Mitochondrial Matrix ReactionCatalysis307 ACTIVATION 5280769 PubChem-compound ReactionCatalysis304 ACTIVATION 50411-91-1 CAS ReactionCatalysis305 ACTIVATION 5280767 PubChem-compound ReactionCatalysis302 ACTIVATION 14000-31-8 CAS 5280768 PubChem-compound ReactionCatalysis303 ACTIVATION ReactionCatalysis300 ACTIVATION HMDB06404 HMDB CO-A BioCyc CPD-8475 BioCyc Phospholipid Biosynthesis SubPathway HMDB06402 HMDB 72-89-9 CAS CHEBI:15452 ChEBI 1.0 SMILES CCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 389056 ChemSpider ReactionCatalysis2149 ACTIVATION CHEBI:28632 ChEBI C21H36N7O16P3S Coenzyme A 767.11523 10917 PubChem-compound 4.0 CHEBI:27668 ChEBI 1.0 HMDB01070 HMDB 79171-48-5 CAS 10128117 ChemSpider Cytoplasm 3-Hydroxybutyryl-CoA 1.0 10455 ChemSpider CHEBI:27540 ChEBI Cell Trifunctional enzyme subunit beta, mitochondrial Phospholipid Biosynthesis SubPathway C01944 KEGG Compound ACETOACETYL-COA BioCyc 14902 ChemSpider 1.0 CHEBI:15422 ChEBI Very long-chain specific acyl-CoA dehydrogenase, mitochondrial 6557 ChemSpider ReactionCatalysis2150 ACTIVATION 1.0 SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 1.0 388299 ChemSpider HMDB01166 HMDB Crotonoyl-CoA 439214 PubChem-compound (S)-3-Hydroxydodecanoyl-CoA CHEBI:27537 ChEBI Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ReactionCatalysis2153 ACTIVATION Phospholipid Biosynthesis SubPathway SMILES CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 Palmitic acid SubPathwayOutput SubPathwayInput C01832 KEGG Compound Glycerolipid Metabolism SubPathway P11310 UniProt CHEBI:16526 ChEBI 122364-86-7 CAS Medium-chain specific acyl-CoA dehydrogenase, mitochondrial CHEBI:27402 ChEBI CHEBI:27648 ChEBI (S)-Hydroxyhexanoyl-CoA 1.0 9606 TAXONOMY Acetyl-CoA acyltransferase T2-DECENOYL-COA BioCyc C00877 KEGG Compound PW000144 PathWhiz PW000022 PathWhiz 1.3.8.8 false 1.3.8.8 Butyryl-CoA + electron-transfer flavoprotein ↔ Crotonoyl-CoA + Reduced electron-transfer flavoprotein REVERSIBLE 392413 ChemSpider 4.2.1.17 false 4.2.1.17 3-Hydroxybutyryl-CoA ↔ Crotonoyl-CoA + Water REVERSIBLE Fatty Acid Elongation In Mitochondria SubPathway 145018 ChemSpider 10018-93-6 CAS 5893 PubChem-compound C25H42N7O18P3S 3-Hydroxybutyryl-CoA 853.152 Glutaryl-CoA dehydrogenase, mitochondrial HMDB02111 HMDB CHEBI:28325 ChEBI Trifunctional enzyme subunit alpha, mitochondrial 1420-36-6 CAS CHEBI:15377 ChEBI CHEBI:16347 ChEBI 3-ketoacyl-CoA thiolase, mitochondrial CHEBI:15378 ChEBI SMILES [H+] HMDB02009 HMDB C00527 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB03571 HMDB HMDB00062 HMDB CHEBI:15491 ChEBI 389499 ChemSpider 389498 ChemSpider CHEBI:27466 ChEBI 280 PubChem-compound Glutaryl-CoA dehydrogenase, mitochondrial 26332261 ChemSpider 2.3.1.9 false 2.3.1.9 2 Acetyl-CoA ↔ Acetoacetyl-CoA + Coenzyme A REVERSIBLE HMDB01487 HMDB 4444333 ChemSpider 1.0 4444334 ChemSpider 1.0 4444335 ChemSpider SMILES CCCCCC(=O)SCCN=C(O)CCN=C(O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)N1C=NC2=C(N)N=CN=C12 CHEBI:15345 ChEBI (2E)-Tetradecenoyl-CoA Glutaryl-CoA 4.0 4444331 ChemSpider 46173176 PubChem-compound 6244-92-4 CAS 10018-94-7 CAS HMDB01484 HMDB 1.0 439252 PubChem-compound 15667 PubChem-compound HMDB00045 HMDB 1.0 Long-chain specific acyl-CoA dehydrogenase, mitochondrial L-Palmitoylcarnitine 1-CARBOXYCYCLOHEXANOYL-COA BioCyc 1.0 electron-transfer flavoprotein CHEBI:15351 ChEBI 388388 ChemSpider CHEBI:15473 ChEBI 85-61-0 CAS Carnitine O- palmitoyltransferase 2, mitochondrial Enoyl-CoA hydratase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial 3-ketoacyl-CoA thiolase, mitochondrial Carnitine O- palmitoyltransferase 1, liver isoform Long-chain- fatty-acid-- CoA ligase 1 Enoyl-CoA hydratase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial 3-ketoacyl-CoA thiolase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial