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HMDB01346 HMDB CPD-535 BioCyc 17215925 ChemSpider Phosphocarrier protein HPr GDP-mannose 4,6-dehydratase 388350 ChemSpider SMILES OC[C@H]1O[C@H](O[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O 937 ChemSpider Galactose-1-phosphate uridylyltransferase α-D-mannose 1-phosphate 18186-48-6 CAS HMDB00250 HMDB ReactionCoupledTransportCatalysis172 ACTIVATION 2956-16-3 CAS UDP-GLACTOSE BioCyc Glucose-specific phosphotransferase enzyme IIA component NADH 439153 PubChem-compound SMILES O 1.0 1.0 1.0 C6H12O6 Beta-D-Glucose 180.06339 Pyrophosphate Glucose-6-phosphate isomerase 1.0 58238 ChemSpider 1.0 6133 PubChem-compound C00325 KEGG Compound 439709 PubChem-compound 1.0 alpha-D-glucose-1-phosphate 2616-64-0 CAS NAD PTS system mannose-specific EIIAB component 53188-23-1 CAS PTS system glucose-specific EIICB component 643-13-0 CAS Mannose-6-phosphate isomerase 559142 ChemSpider CHEBI:15846 ChEBI HMDB00935 HMDB colanic acid building blocks biosynthesis P32055 UniProt alpha-D-Glucose 6-phosphate C6H13O9P alpha-D-Glucose 6-phosphate 260.02972 C6H13O9P alpha-D-glucose-1-phosphate 260.02972 SMP00967 SMPDB P0AA04 UniProt 53-59-8 CAS CHEBI:15820 ChEBI ReactionCoupledTransportCatalysis198 ACTIVATION 1038 PubChem-compound C05345 KEGG Compound CHEBI:17200 ChEBI CHEBI:16474 ChEBI HMDB59597 HMDB HMDB00902 HMDB Reaction3578 false GDP-L-fucose + Uridine diphosphate glucose + Uridine diphosphate glucuronic acid + Uridine diphosphategalactose → colanic acid LEFT_TO_RIGHT CHEBI:16908 ChEBI HMDB00124 HMDB Fructose 6-phosphate C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 53477679 PubChem-compound UDP-GLUCURONATE BioCyc PW000951 PathWhiz CHEBI:15713 ChEBI 133-89-1 CAS C00221 KEGG Compound 1.0 NADPH 6830 PubChem-compound 1010 ChemSpider GO:0070258 GENE ONTOLOGY P00946 UniProt NADP ReactionCatalysis3418 ACTIVATION PPI BioCyc CHEBI:15946 ChEBI C21H30N7O17P3 NADPH 745.0911 Reaction3448 false Beta-D-Glucose 6-phosphate → Beta-D-Fructose 6-phosphate LEFT_TO_RIGHT C21H29N7O17P3 NADP 744.08325 Reaction3566 false Hydrogen Ion + Uridine triphosphate + alpha-D-glucose-1-phosphate → Pyrophosphate + Uridine diphosphate glucose LEFT_TO_RIGHT Colanic acid biosynthesis protein wcaK mannose PTS permease BiologicalState109 2.0 alpha-D-mannose 1.0 α-D-mannose 6-phosphate 388554 ChemSpider NADPH BioCyc C15H22N2O18P2 Uridine diphosphate glucuronic acid 580.0343 C10H16N5O14P3 Guanosine triphosphate 522.99066 Hydrogen Ion 389526 ChemSpider HMDB00217 HMDB C16H23N5O15P2 GDP-4-Dehydro-6-deoxy-D-mannose 587.0666 1.0 D-Fructose UTP--glucose-1-phosphate uridylyltransferase_ glucose PTS permease C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc 1.1.1.22 false 1.1.1.22 2 NAD + Uridine diphosphate glucose + Water → 3 Hydrogen Ion + 2 NADH + Uridine diphosphate glucuronic acid LEFT_TO_RIGHT 58-68-4 CAS P69797 UniProt Glucose-6-phosphate isomerase C9H15N2O15P3 Uridine triphosphate 483.96854 Phosphoglucomutase-1 1.0 Mannose permease IID component ReactionCoupledTransport114 false HPr - phosphorylated + alpha-D-mannose → HPr + α-D-mannose 6-phosphate LEFT_TO_RIGHT galactose-1-phosphate uridylyltransferase C6H13O9P Fructose 6-phosphate 260.02972 2.0 C6H12O6 D-Fructose 180.06339 GDP-MANNOSE BioCyc HMDB00221 HMDB SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O CHEBI:67119 ChEBI β-D-fructofuranose 6-phosphate C00006 KEGG Compound ReactionCoupledTransportCatalysis148 ACTIVATION CHEBI:18009 ChEBI C00001 KEGG Compound UDP-glucose 6-dehydrogenase Galactose-1-phosphate uridylyltransferase 2.0 CHEBI:18361 ChEBI P69783 UniProt C00005 KEGG Compound 1.0 HMDB03971 HMDB 1.0 C00004 KEGG Compound Inner Membrane C00003 KEGG Compound Phosphocarrier protein HPr SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O P69786 UniProt C6H13O9P Beta-D-Fructose 6-phosphate 260.02972 1.0 GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O Beta-D-Fructose 6-phosphate 17473 PubChem-compound 1.0 69507 PubChem-compound Mannose permease IIC component 53-57-6 CAS 388775 ChemSpider 388538 ChemSpider C21H28N7O14P2 NAD 664.11694 C6H11O9P β-D-fructofuranose 6-phosphate 258.01517 P09148 UniProt CHEBI:16955 ChEBI CHEBI:17009 ChEBI C01222 KEGG Compound Mannose-6-phosphate isomerase FRUCTOSE-6P BioCyc SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)C(=O)N1 C00013 KEGG Compound 440641 PubChem-compound O7P2 Pyrophosphate 173.91193 Uridine diphosphate glucose 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT 17372 ChemSpider NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 GDP-L-fucose synthase 4.2.1.47 false 4.2.1.47 Guanosine diphosphate mannose → GDP-4-Dehydro-6-deoxy-D-mannose + Water LEFT_TO_RIGHT Uridine triphosphate 1.1.1.271 false 1.1.1.271 GDP-4-Dehydro-6-deoxy-D-mannose + Hydrogen Ion + NADPH → GDP-L-fucose + NADP LEFT_TO_RIGHT 562 TAXONOMY Beta-D-Glucose 6-phosphate 1.0 H Hydrogen Ion 1.007825 C00029 KEGG Compound C6H11O9P α-D-mannose 6-phosphate 258.01517 CHEBI:15996 ChEBI 5.3.1.8 false 5.3.1.8 α-D-mannose 6-phosphate ↔ β-D-fructofuranose 6-phosphate REVERSIBLE C6H12O6 alpha-D-mannose 180.06339 HMDB01095 HMDB GDP-L-fucose 53-84-9 CAS GDP-4-Dehydro-6-deoxy-D-mannose Uridine diphosphate glucuronic acid α-D-mannose 1-phosphate 62713 ChemSpider Guanosine triphosphate Colanic acid biosynthesis protein wcaK phosphoglucose isomerase Reaction3361 false Guanosine triphosphate + Hydrogen Ion + α-D-mannose 1-phosphate → Guanosine diphosphate mannose + Pyrophosphate LEFT_TO_RIGHT 5.4.2.8 false 5.4.2.8 α-D-mannose 6-phosphate ↔ α-D-mannose 1-phosphate REVERSIBLE 1.0 C16H25N5O15P2 GDP-L-fucose 589.0822 P36871 UniProt 1.0 15839-70-0 CAS 1.0 Reaction2950 false Uridine diphosphate glucose → Uridine diphosphategalactose LEFT_TO_RIGHT CHEBI:58409 ChEBI C02336 KEGG Compound ReactionCatalysis2929 ACTIVATION SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 5682 ChemSpider ReactionCatalysis2930 ACTIVATION SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 Water CHEBI:28645 ChEBI 492-61-5 CAS PTS system glucose-specific EIICB component SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS 1.0 HMDB00302 HMDB P0AEP3 UniProt C00044 KEGG Compound 5675 ChemSpider Mannose permease IID component HMDB03498 HMDB Phosphoglucomutase-1 Mannose permease IIC component Uridine diphosphategalactose HMDB00660 HMDB C00167 KEGG Compound 1.0 SMILES C[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@@H](O)C1=O C00052 KEGG Compound SMILES C[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@H](O)[C@@H]1O 1.0 439427 PubChem-compound UTP BioCyc 64689 PubChem-compound 5903 ChemSpider UDP-glucose 6-dehydrogenase 2.0 18068 PubChem-compound 7732-18-5 CAS 388299 ChemSpider HMDB01163 HMDB Phosphomannomutase SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O Mannose-1-phosphate guanylyltransferase 2.0 439211 PubChem-compound 1.0 CHEBI:17719 ChEBI 1.0 16522 ChemSpider P76373 UniProt ReactionCatalysis3490 ACTIVATION CHEBI:16084 ChEBI GDP-mannose 4,6-dehydratase GDP-L-fucose synthase CHEBI:28729 ChEBI 1.0 P24174 UniProt P24175 UniProt P0A6T1 UniProt 439446 PubChem-compound 17069 ChemSpider HMDB00516 HMDB ReactionCoupledTransport164 false D-Fructose + HPr - phosphorylated → Fructose 6-phosphate + HPr LEFT_TO_RIGHT P71242 UniProt Beta-D-Glucose 962 PubChem-compound C16H25N5O16P2 Guanosine diphosphate mannose 605.07715 SMILES OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O Beta-D-Glucose 6-phosphate C00075 KEGG Compound UDP-glucose 6-dehydrogenase 5893 PubChem-compound HMDB02111 HMDB C00080 KEGG Compound C00085 KEGG Compound C01172 KEGG Compound GUANOSINE_DIPHOSPHATE_FUCOSE BioCyc 3.0 Reaction3510 false alpha-D-Glucose 6-phosphate ↔ alpha-D-glucose-1-phosphate REVERSIBLE CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Reaction3509 true Beta-D-Glucose 6-phosphate ↔ alpha-D-Glucose 6-phosphate REVERSIBLE SMILES OCC1OC(O)C(O)C(O)C1O SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O 6569 ChemSpider 5886 PubChem-compound HMDB01273 HMDB GTP BioCyc 3123-67-9 CAS 1.0 C00096 KEGG Compound ReactionCatalysis3555 ACTIVATION CHEBI:60332 ChEBI P0AC88 UniProt HMDB01487 HMDB 644102 PubChem-compound C15H24N2O17P2 Uridine diphosphategalactose 566.055 SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 2.0 2.0 Glucose-specific phosphotransferase enzyme IIA component SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O 22833512 PubChem-compound 1.0 18396 PubChem-compound H2O Water 18.010565 SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O α-D-mannose 6-phosphate ReactionCatalysis3329 ACTIVATION NADH BioCyc 86-01-1 CAS SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O 2.0 ReactionCatalysis3324 ACTIVATION SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O NAD BioCyc 63-39-8 CAS ReactionCatalysis2917 ACTIVATION PTS system mannose-specific EIIAB component 1.0 Guanosine diphosphate mannose SMILES OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O CHEBI:57634 ChEBI Phosphomannomutase HMDB00285 HMDB Mannose-1-phosphate guanylyltransferase HMDB00286 HMDB SMILES OC[C@@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O P69801 UniProt UTP--glucose-1-phosphate uridylyltransferase_ ReactionCatalysis2924 ACTIVATION ReactionCatalysis3330 ACTIVATION P69805 UniProt CHEBI:15903 ChEBI SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O SMILES O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O Glucose-6- phosphate isomerase Mannose-6- phosphate isomerase Phosphomannomutase Mannose-1- phosphate guanylyltransferase GDP-mannose 4,6-dehydratase GDP-L-fucose synthase Phosphoglucomutase- 1 UTP--glucose- 1-phosphate uridylyltransferase_ Galactose-1- phosphate uridylyltransferase UDP-glucose 6-dehydrogenase Colanic acid biosynthesis protein wcaK Phosphocarrier protein HPr Phosphocarrier protein HPr Mannose permease IID component Mannose permease IIC component PTS system mannose- specific EIIAB component Phosphocarrier protein HPr Phosphocarrier protein HPr PTS system glucose- specific EIICB component Glucose- specific phosphotransferase enzyme IIA component Phosphocarrier protein HPr Phosphocarrier protein HPr Mannose permease IID component Mannose permease IIC component PTS system mannose- specific EIIAB component Beta-D-Glucose 6-phosphate Beta-D-Fructose 6-phosphate α-D-mannose 6-phosphate α-D-mannose 6-phosphate α-D-mannose 1-phosphate GTP H + Guanosine diphosphate mannose PP i H 2 O GDP-4- Dehydro-6- deoxy-D- mannose NADPH H + GDP-L-fucose NADP alpha-D-Glucose 6-phosphate alpha-D- glucose-1- phosphate Uridine triphosphate H + PP i Uridine diphosphate glucose Uridine diphosphategalactose NAD H 2 O Uridine diphosphate glucuronic acid NADH H + Uridine diphosphategalactose Uridine diphosphate glucose GDP-L-fucose Uridine diphosphate glucuronic acid D-Fructose Fructose 6-phosphate Beta-D-Glucose alpha-D-mannose
HMDB01346 HMDB CPD-535 BioCyc 17215925 ChemSpider Phosphocarrier protein HPr GDP-mannose 4,6-dehydratase 388350 ChemSpider SMILES OC[C@H]1O[C@H](O[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O 937 ChemSpider Galactose-1-phosphate uridylyltransferase α-D-mannose 1-phosphate 18186-48-6 CAS HMDB00250 HMDB ReactionCoupledTransportCatalysis172 ACTIVATION 2956-16-3 CAS UDP-GLACTOSE BioCyc Glucose-specific phosphotransferase enzyme IIA component NADH 439153 PubChem-compound SMILES O 1.0 1.0 1.0 C6H12O6 Beta-D-Glucose 180.06339 Pyrophosphate Glucose-6-phosphate isomerase 1.0 58238 ChemSpider 1.0 6133 PubChem-compound C00325 KEGG Compound 439709 PubChem-compound 1.0 alpha-D-glucose-1-phosphate 2616-64-0 CAS NAD PTS system mannose-specific EIIAB component 53188-23-1 CAS PTS system glucose-specific EIICB component 643-13-0 CAS Mannose-6-phosphate isomerase 559142 ChemSpider CHEBI:15846 ChEBI HMDB00935 HMDB colanic acid building blocks biosynthesis P32055 UniProt alpha-D-Glucose 6-phosphate C6H13O9P alpha-D-Glucose 6-phosphate 260.02972 C6H13O9P alpha-D-glucose-1-phosphate 260.02972 http://identifiers.org/smpdb/SMP00967 SMPDB P0AA04 UniProt 53-59-8 CAS CHEBI:15820 ChEBI ReactionCoupledTransportCatalysis198 ACTIVATION 1038 PubChem-compound C05345 KEGG Compound CHEBI:17200 ChEBI CHEBI:16474 ChEBI HMDB59597 HMDB HMDB00902 HMDB Reaction3578 false GDP-L-fucose + Uridine diphosphate glucose + Uridine diphosphate glucuronic acid + Uridine diphosphategalactose → colanic acid LEFT_TO_RIGHT CHEBI:16908 ChEBI HMDB00124 HMDB Fructose 6-phosphate C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 53477679 PubChem-compound UDP-GLUCURONATE BioCyc PW000951 PathWhiz CHEBI:15713 ChEBI 133-89-1 CAS C00221 KEGG Compound 1.0 NADPH 6830 PubChem-compound 1010 ChemSpider GO:0070258 GENE ONTOLOGY P00946 UniProt NADP ReactionCatalysis3418 ACTIVATION PPI BioCyc CHEBI:15946 ChEBI C21H30N7O17P3 NADPH 745.0911 Reaction3448 false Beta-D-Glucose 6-phosphate → Beta-D-Fructose 6-phosphate LEFT_TO_RIGHT C21H29N7O17P3 NADP 744.08325 Reaction3566 false Hydrogen Ion + Uridine triphosphate + alpha-D-glucose-1-phosphate → Pyrophosphate + Uridine diphosphate glucose LEFT_TO_RIGHT Colanic acid biosynthesis protein wcaK mannose PTS permease BiologicalState109 Escherichia coli, Inner Membrane 2.0 alpha-D-mannose 1.0 α-D-mannose 6-phosphate 388554 ChemSpider NADPH BioCyc C15H22N2O18P2 Uridine diphosphate glucuronic acid 580.0343 C10H16N5O14P3 Guanosine triphosphate 522.99066 Hydrogen Ion 389526 ChemSpider HMDB00217 HMDB C16H23N5O15P2 GDP-4-Dehydro-6-deoxy-D-mannose 587.0666 1.0 D-Fructose UTP--glucose-1-phosphate uridylyltransferase_ glucose PTS permease C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc 1.1.1.22 false 1.1.1.22 2 NAD + Uridine diphosphate glucose + Water → 3 Hydrogen Ion + 2 NADH + Uridine diphosphate glucuronic acid LEFT_TO_RIGHT 58-68-4 CAS P69797 UniProt Glucose-6-phosphate isomerase C9H15N2O15P3 Uridine triphosphate 483.96854 Phosphoglucomutase-1 1.0 Mannose permease IID component ReactionCoupledTransport114 false HPr - phosphorylated + alpha-D-mannose → HPr + α-D-mannose 6-phosphate LEFT_TO_RIGHT galactose-1-phosphate uridylyltransferase C6H13O9P Fructose 6-phosphate 260.02972 2.0 C6H12O6 D-Fructose 180.06339 GDP-MANNOSE BioCyc HMDB00221 HMDB SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O CHEBI:67119 ChEBI β-D-fructofuranose 6-phosphate C00006 KEGG Compound ReactionCoupledTransportCatalysis148 ACTIVATION CHEBI:18009 ChEBI C00001 KEGG Compound UDP-glucose 6-dehydrogenase Galactose-1-phosphate uridylyltransferase 2.0 CHEBI:18361 ChEBI P69783 UniProt C00005 KEGG Compound 1.0 HMDB03971 HMDB 1.0 C00004 KEGG Compound Inner Membrane C00003 KEGG Compound Phosphocarrier protein HPr SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O P69786 UniProt C6H13O9P Beta-D-Fructose 6-phosphate 260.02972 1.0 GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O Beta-D-Fructose 6-phosphate 17473 PubChem-compound 1.0 69507 PubChem-compound Mannose permease IIC component 53-57-6 CAS 388775 ChemSpider 388538 ChemSpider C21H28N7O14P2 NAD 664.11694 C6H11O9P β-D-fructofuranose 6-phosphate 258.01517 P09148 UniProt CHEBI:16955 ChEBI CHEBI:17009 ChEBI C01222 KEGG Compound Mannose-6-phosphate isomerase FRUCTOSE-6P BioCyc SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)C(=O)N1 C00013 KEGG Compound 440641 PubChem-compound O7P2 Pyrophosphate 173.91193 Uridine diphosphate glucose 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT 17372 ChemSpider NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 GDP-L-fucose synthase 4.2.1.47 false 4.2.1.47 Guanosine diphosphate mannose → GDP-4-Dehydro-6-deoxy-D-mannose + Water LEFT_TO_RIGHT Uridine triphosphate 1.1.1.271 false 1.1.1.271 GDP-4-Dehydro-6-deoxy-D-mannose + Hydrogen Ion + NADPH → GDP-L-fucose + NADP LEFT_TO_RIGHT 562 TAXONOMY Beta-D-Glucose 6-phosphate 1.0 H Hydrogen Ion 1.007825 C00029 KEGG Compound C6H11O9P α-D-mannose 6-phosphate 258.01517 CHEBI:15996 ChEBI 5.3.1.8 false 5.3.1.8 α-D-mannose 6-phosphate ↔ β-D-fructofuranose 6-phosphate REVERSIBLE C6H12O6 alpha-D-mannose 180.06339 HMDB01095 HMDB GDP-L-fucose 53-84-9 CAS GDP-4-Dehydro-6-deoxy-D-mannose Uridine diphosphate glucuronic acid α-D-mannose 1-phosphate 62713 ChemSpider Guanosine triphosphate Colanic acid biosynthesis protein wcaK phosphoglucose isomerase Reaction3361 false Guanosine triphosphate + Hydrogen Ion + α-D-mannose 1-phosphate → Guanosine diphosphate mannose + Pyrophosphate LEFT_TO_RIGHT 5.4.2.8 false 5.4.2.8 α-D-mannose 6-phosphate ↔ α-D-mannose 1-phosphate REVERSIBLE 1.0 C16H25N5O15P2 GDP-L-fucose 589.0822 P36871 UniProt 1.0 15839-70-0 CAS 1.0 Reaction2950 false Uridine diphosphate glucose → Uridine diphosphategalactose LEFT_TO_RIGHT CHEBI:58409 ChEBI C02336 KEGG Compound ReactionCatalysis2929 ACTIVATION SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 5682 ChemSpider ReactionCatalysis2930 ACTIVATION SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 1.0 Water CHEBI:28645 ChEBI 492-61-5 CAS PTS system glucose-specific EIICB component SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS 1.0 HMDB00302 HMDB P0AEP3 UniProt C00044 KEGG Compound 5675 ChemSpider Mannose permease IID component HMDB03498 HMDB Phosphoglucomutase-1 Mannose permease IIC component Uridine diphosphategalactose HMDB00660 HMDB C00167 KEGG Compound 1.0 SMILES C[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@@H](O)C1=O C00052 KEGG Compound SMILES C[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@H](O)[C@@H]1O 1.0 439427 PubChem-compound UTP BioCyc 64689 PubChem-compound 5903 ChemSpider UDP-glucose 6-dehydrogenase 2.0 18068 PubChem-compound 7732-18-5 CAS 388299 ChemSpider HMDB01163 HMDB Phosphomannomutase SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O Mannose-1-phosphate guanylyltransferase 2.0 439211 PubChem-compound 1.0 CHEBI:17719 ChEBI 1.0 16522 ChemSpider P76373 UniProt ReactionCatalysis3490 ACTIVATION CHEBI:16084 ChEBI GDP-mannose 4,6-dehydratase GDP-L-fucose synthase CHEBI:28729 ChEBI 1.0 P24174 UniProt P24175 UniProt P0A6T1 UniProt 439446 PubChem-compound 17069 ChemSpider HMDB00516 HMDB ReactionCoupledTransport164 false D-Fructose + HPr - phosphorylated → Fructose 6-phosphate + HPr LEFT_TO_RIGHT P71242 UniProt Beta-D-Glucose 962 PubChem-compound C16H25N5O16P2 Guanosine diphosphate mannose 605.07715 SMILES OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O Beta-D-Glucose 6-phosphate C00075 KEGG Compound UDP-glucose 6-dehydrogenase 5893 PubChem-compound HMDB02111 HMDB C00080 KEGG Compound C00085 KEGG Compound C01172 KEGG Compound GUANOSINE_DIPHOSPHATE_FUCOSE BioCyc 3.0 Reaction3510 false alpha-D-Glucose 6-phosphate ↔ alpha-D-glucose-1-phosphate REVERSIBLE CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Reaction3509 true Beta-D-Glucose 6-phosphate ↔ alpha-D-Glucose 6-phosphate REVERSIBLE SMILES OCC1OC(O)C(O)C(O)C1O SMILES OC1OC(COP([O-])([O-])=O)C(O)C(O)C1O 6569 ChemSpider 5886 PubChem-compound HMDB01273 HMDB GTP BioCyc 3123-67-9 CAS 1.0 C00096 KEGG Compound ReactionCatalysis3555 ACTIVATION CHEBI:60332 ChEBI P0AC88 UniProt HMDB01487 HMDB 644102 PubChem-compound C15H24N2O17P2 Uridine diphosphategalactose 566.055 SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 2.0 2.0 Glucose-specific phosphotransferase enzyme IIA component SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O 22833512 PubChem-compound 1.0 18396 PubChem-compound H2O Water 18.010565 SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O α-D-mannose 6-phosphate ReactionCatalysis3329 ACTIVATION NADH BioCyc 86-01-1 CAS SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O 2.0 ReactionCatalysis3324 ACTIVATION SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O NAD BioCyc 63-39-8 CAS ReactionCatalysis2917 ACTIVATION PTS system mannose-specific EIIAB component 1.0 Guanosine diphosphate mannose SMILES OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O CHEBI:57634 ChEBI Phosphomannomutase HMDB00285 HMDB Mannose-1-phosphate guanylyltransferase HMDB00286 HMDB SMILES OC[C@@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O P69801 UniProt UTP--glucose-1-phosphate uridylyltransferase_ ReactionCatalysis2924 ACTIVATION ReactionCatalysis3330 ACTIVATION P69805 UniProt CHEBI:15903 ChEBI SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O SMILES O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O