Quantitative metabolomics services for biomarker discovery and validation.
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Lanosterol 14-alpha demethylase Lanosterol 14-alpha demethylase Lanosterol 14-alpha demethylase Lamin-B receptor Methylsterol monooxygenase 1 Methylsterol monooxygenase 1 Methylsterol monooxygenase 1 Sterol-4- alpha- carboxylate 3- dehydrogenase, decarboxylating 3-keto-steroid reductase Methylsterol monooxygenase 1 Methylsterol monooxygenase 1 Methylsterol monooxygenase 1 Sterol-4- alpha- carboxylate 3- dehydrogenase, decarboxylating 3-keto-steroid reductase 3-beta- hydroxysteroid- Delta(8),Delta(7)- isomerase Lathosterol oxidase 7- dehydrocholesterol reductase Delta(24)- sterol reductase Lanosterol O 2 FMNH2 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta- 8,24-dien-3β-ol Formic acid H 2 O Flavin Mononucleotide H + O 2 FMNH2 4,4-dimethyl-14α-formyl-5α-cholesta-8,24- dien-3β-ol Formic acid H 2 O H + Flavin Mononucleotide O 2 FMNH2 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol Formic acid H 2 O H + Flavin Mononucleotide NADPH H + 4,4-Dimethyl-5a-cholesta-8,24-dien-3-b-ol NADP Fe2+ H + O 2 4α-hydroxymethyl-4β-methyl-5α-cholesta- 8,24-dien-3β-ol Fe3+ H 2 O Fe2+ H + O 2 4α-Formyl-4β-methyl-5α-cholesta-8,24-dien- 3β-ol Fe3+ H 2 O Fe2+ H + O 2 4a-Carboxy-4b-methyl-5a-cholesta-8,24-dien- 3b-ol Fe3+ H 2 O NADP 3-Keto-4-methylzymosterol CO 2 NADPH NADP 4a-Methylzymosterol NADPH H + Fe2+ H + O 2 4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol Fe3+ H 2 O Fe2+ H + O 2 4a-Formyl-5a-cholesta-8,24-dien-3b-ol Fe3+ H 2 O Fe2+ H + O 2 4a-carboxy-5a-cholesta-8,24-dien-3b-ol Fe3+ H 2 O NADP 5α-cholesta-8,24-dien-3-one NADPH CO 2 NADP Zymosterol H + NADPH 5a-Cholesta-7,24-dien-3b-ol Fe2+ H + O 2 7-Dehydrodesmosterol Fe3+ H 2 O NADP Desmosterol H + NADPH NADP Cholesterol H + NADPH Heme Heme Heme Iron Iron Iron Iron Iron Iron Iron FAD Mevalonate Pathway Endoplasmic Reticulum Inner Nuclear Membrane Nucleus Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane