Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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Reverse transcriptase/RNaseH ABC transporter, substrate- binding lipoprotein Multidrug resistance- associated protein 4 Multidrug resistance- associated protein 4 Adenosine 5'- monophosphoramidase HINT1 N- acetylgalactosamine- 6-sulfatase Beta- galactosidase Sialidase-1 Tenofovir Diphosphate dATP Tenofovir Tenofovir Tenofovir alafenamide Tenofovir alafenamide Tenofovir Tenofovir Monophosphate ATP ADP ATP ADP Tenofovir alanine L-Alanine Lysosomal protective protein Liver carboxylesterase 1 Viral Proteins Nucleoside diphosphate kinase B Adenylate kinase isoenzyme 1 Nucleoside diphosphate kinase A Adenylate kinase 2, mitochondrial Magnesium Magnesium HHV Infected Cell Integration Nucleus Viral RNA Viral DNA Less Viral DNA is transported into the nucleus, therefore, less viral DNA is integrated into the host DNA. Transcription Translation Less viral proteins produced, fewer viruses can form. Cytosol Blood vessel Tenofovir Diphosphate inhibits the activity of reverse transcriptase by competing with its substrate dATP. Viral DNA Viral mRNA Viral mRNA Hepatic Cell Liver Tenofovir Diphosphate is integrated into DNA which causes viral DNA chain termination. Cytosol Blood Vessel
Nucleus pol CDR20291_0805 ABCC4 ABCC4 HINT1 GALNS GLB1 NEU1 Tenofovir Diphosphate dATP Tenofovir Tenofovir Tenofovir alafenamide Tenofovir alafenamide Tenofovir Tenofovir Monophosphate Adenosine triphosphate Adenosine diphosphate Adenosine triphosphate Adenosine diphosphate Tenofovir alanine L-Alanine CTSA CES1 Viral Proteins NME2 AK1 NME1 AK2
pol CDR20291_0805 ABCC4 ABCC4 HINT1 GALNS GLB1 NEU1 TenfDP dATP TenFvr TenFvr Ten ala Ten ala TenFvr TnfvrMP ATP ADP ATP ADP Ten ala Ala CTSA CES1 Vir Pro NME2 AK1 NME1 AK2 Mg2+ Mg2+ HHV Infected Cell Integration Nucleus Viral RNA Viral DNA Less Viral DNA is transported into the nucleus, therefore, less viral DNA is integrated into the host DNA. Transcription Translation Less viral proteins produced, fewer viruses can form. Cytosol Blood vessel Tenofovir Diphosphate inhibits the activity of reverse transcriptase by competing with its substrate dATP. Viral DNA Viral mRNA Viral mRNA Hepatic Cell Liver Tenofovir Diphosphate is integrated into DNA which causes viral DNA chain termination. Cytosol Blood Vessel
Nucleus pol CDR20291_0805 ABCC4 ABCC4 HINT1 GALNS GLB1 NEU1 TenfDP dATP TenFvr TenFvr Ten ala Ten ala TenFvr TnfvrMP ATP ADP ATP ADP Ten ala Ala CTSA CES1 Vir Pro NME2 AK1 NME1 AK2