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CHEBI:16015 ChEBI 6022 PubChem-compound C23H38N7O17P3S Acetyl-CoA 809.1258 937 ChemSpider 22138-53-0 CAS Aspartokinase HMDB01341 HMDB NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 439153 PubChem-compound 57 ChemSpider Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial http://identifiers.org/smpdb/SMP02444 SMPDB HMDB12249 HMDB 50 ChemSpider 1.0 Q8RXU4 UniProt HMDB00148 HMDB 809 ChemSpider C00441 KEGG Compound NAD OXALACETIC_ACID BioCyc ATP BioCyc H4N Ammonium 18.034374 1.0 2.0 19796801 PubChem-compound 6288 PubChem-compound 1.0 HMDB01206 HMDB 5745 ChemSpider 5742 ChemSpider L-ASPARTATE BioCyc CHEBI:16474 ChEBI Acetaldehyde ReactionCatalysis7209 ACTIVATION HMDB59597 HMDB GO:0009507 GENE ONTOLOGY 1.0 C4H10NO6P O-Phosphohomoserine 199.02457 HMDB00123 HMDB Aspartokinase 1, chloroplastic Aspartokinase 2, chloroplastic HMDB00005 HMDB threonine deaminase C00109 KEGG Compound Acetyl-CoA 945 ChemSpider P10869 UniProt 1010 ChemSpider Oxoglutaric acid SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS HMDB41827 HMDB Aspartate semialdehyde dehydrogenase 1.0 1.0 HMDB01423 HMDB Hydrogen Ion HMDB00217 HMDB Cytosol Probable low-specificity L-threonine aldolase 1 BiologicalState225 Arabidopsis thaliana, Cell, chloroplast Adenosine triphosphate HMDB00208 HMDB 1.0 L-Aspartate-semialdehyde HMDB00221 HMDB C00009 KEGG Compound C00008 KEGG Compound 1.0 HMDB00223 HMDB Q8VYI4 UniProt C00006 KEGG Compound SMILES N[C@@H](CCOP(O)(O)=O)C(O)=O Q0WM29 UniProt CHEBI:18009 ChEBI C00001 KEGG Compound C00005 KEGG Compound CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound 2-OXOBUTANOATE BioCyc C00002 KEGG Compound HMDB01429 HMDB ReactionCatalysis6301 ACTIVATION Adenosine diphosphate Q9ZSS6 UniProt C21H28N7O14P2 NAD 664.11694 44367445 PubChem-compound 1.0 C01342 KEGG Compound C00010 KEGG Compound TCA cycle SubPathway glycolysis and pyruvate dehydrogenase SubPathway propanoate metabolism SubPathway C01102 KEGG Compound NAD(P) BioCyc 12126 ChemSpider H Hydrogen Ion 1.007825 SubPathwayInteraction3854 SubPathwayReaction SubPathway3854Reaction C00263 KEGG Compound 56-65-5 CAS SubPathwayInteraction3852 SubPathwayReaction SubPathway3852Reaction 53-84-9 CAS 4.0 SubPathwayInteraction3853 SubPathway3853Reaction SubPathwayReaction C00026 KEGG Compound C00025 KEGG Compound 1.0 C00024 KEGG Compound L-Aspartic acid NADPH SMILES N[C@@H](CC=O)C(O)=O SMILES NC(CC(=O)OP(O)(O)=O)C(O)=O 1.0 Oxalacetic acid 2.0 CL:0000000 CELL TYPE ONTOLOGY 1.0 C00037 KEGG Compound C00036 KEGG Compound L-Homoserine SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 328-50-7 CAS (2Z)-2-aminobut-2-enoate Aspartokinase ReactionCatalysis7266 ACTIVATION 1.0 C00049 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O CHEBI:58739 ChEBI HMDB00538 HMDB ReactionCatalysis7165 ACTIVATION 12647 PubChem-compound SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS 1.0 HMDB00990 HMDB L-BETA-ASPARTYL-P BioCyc 56-86-0 CAS 1.0 4.0 ReactionCatalysis7293 ACTIVATION ReactionCatalysis7292 ACTIVATION ReactionCatalysis7291 ACTIVATION C10H16N5O13P3 Adenosine triphosphate 506.99576 aspartate kinase / homoserine dehydrogenase C00188 KEGG Compound CHEBI:17053 ChEBI 56-40-6 CAS Acetaldehyde ReactionCatalysis7290 ACTIVATION C2H4O Acetaldehyde 44.026215 962 PubChem-compound 151187 PubChem-compound C4H9NO3 L-Threonine 119.05824 PW000940 PathWhiz 5800 ChemSpider SMILES CCC(=N)C([O-])=O Phosphate Phosphate C00080 KEGG Compound 730 ChemSpider 4.2.3.1 false 4.2.3.1 O-Phosphohomoserine + Water → L-Threonine + Phosphate LEFT_TO_RIGHT 2.7.2.4 false 2.7.2.4 Hydrogen Ion + L-Aspartate-semialdehyde + NADPH → L-Homoserine + NADP LEFT_TO_RIGHT C00084 KEGG Compound 15106-57-7 CAS SMILES N[C@@H](CCC(O)=O)C(O)=O 14265-44-2 CAS O23653 UniProt 832 PubChem-compound 58-64-0 CAS 1.0 C4H6O3 2-Ketobutyric acid 102.03169 C4H7NO4 L-Aspartic acid 133.0375 1.0 444493 PubChem-compound 1.0 22833512 PubChem-compound ACETYL-COA BioCyc CHEBI:18051 ChEBI H2O Water 18.010565 SMILES NCC(O)=O 2-Ketobutyric acid NADH BioCyc C4H9NO3 L-Homoserine 119.05824 NAD BioCyc ReactionCatalysis7252 ACTIVATION Transport580 false Acetaldehyde (→) Transport: Arabidopsis thaliana, Cytosol to Arabidopsis thaliana, Cell, Mitochondrion LEFT_TO_RIGHT 56-84-8 CAS L-Threonine 970 PubChem-compound 4.1.2.48 false 4.1.2.48 L-Threonine → Acetaldehyde + Glycine LEFT_TO_RIGHT 1.2.1.4 false 1.2.1.4 Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT Reaction7321 false Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT HMDB00719 HMDB Aspartate kinase 30572 ChemSpider 1.0 17215925 ChemSpider CHEBI:15961 ChEBI O-PHOSPHO-L-HOMOSERINE BioCyc 3702 TAXONOMY C4H4O5 Oxalacetic acid 132.00587 1.0 NADH SMILES N[C@@H](CCO)C(O)=O SMILES O Adenosine triphosphate http://identifiers.org/smpdb/SMP00957 SMPDB 1.0 1.0 6816 PubChem-compound 328-42-7 CAS 51 PubChem-compound CHEBI:15846 ChEBI 2.7.2.4 false 2.7.2.4 Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate LEFT_TO_RIGHT 4.3.1.19 false 4.3.1.19 L-Threonine → (2Z)-2-aminobut-2-enoate + Hydrogen Ion + Water LEFT_TO_RIGHT ADP BioCyc 58 PubChem-compound 53-59-8 CAS Reaction2924 true 2-iminobutanoate + Hydrogen Ion + Water → 2-Ketobutyric acid + Ammonium LEFT_TO_RIGHT THR BioCyc 1.0 1038 PubChem-compound Water GO:0005829 GENE ONTOLOGY C5H6O5 Oxoglutaric acid 146.02153 Reaction2923 true (2Z)-2-aminobut-2-enoate → 2-iminobutanoate LEFT_TO_RIGHT HMDB00902 HMDB CHEBI:16908 ChEBI O4P Phosphate 94.95342 NADPH SMILES CC=C(N)C([O-])=O 1.0 Q8S7B5 UniProt NADP 600-18-0 CAS C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 Mitochondrion NADPH BioCyc GLY BioCyc CHEBI:16857 ChEBI PW000785 PathWhiz 672-15-1 CAS 218 ChemSpider 58-68-4 CAS 72-19-5 CAS 4210-66-6 CAS SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O CHEBI:30915 ChEBI PW000779 PathWhiz C2H5NO2 Glycine 75.03203 Q8L7R2 UniProt ReactionCatalysis7194 ACTIVATION Aspartokinase 2, chloroplastic Reaction7271 false Hydrogen Ion + L-Aspartyl-4-phosphate + NADPH → L-Aspartate-semialdehyde + NADP + Phosphate LEFT_TO_RIGHT Aspartokinase 1, chloroplastic C4H6NO2 (2Z)-2-aminobut-2-enoate 100.040405 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O L-Glutamic acid 6051 ChemSpider 5257127 PubChem-compound C03082 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O GLT BioCyc 53-57-6 CAS http://identifiers.org/smpdb/SMP00802 SMPDB C4H6NO2 2-iminobutanoate 100.040405 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial CHEBI:28938 ChEBI NADP-dependent glyceraldehyde-3-phosphate dehydrogenase SMILES C[C@@H](O)[C@H](N)C(O)=O http://identifiers.org/smpdb/SMP00807 SMPDB 1.0 C21H29N7O14P2 NADH 665.12476 Glycine 5957 PubChem-compound 2.6.1.1 false 2.6.1.1 L-Glutamic acid + Oxalacetic acid ↔ L-Aspartic acid + Oxoglutaric acid REVERSIBLE 2.7.1.39 false 2.7.1.39 Adenosine triphosphate + L-Homoserine → Adenosine diphosphate + Hydrogen Ion + O-Phosphohomoserine LEFT_TO_RIGHT Aspartate aminotransferase 3, chloroplastic Adenosine diphosphate GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 chloroplast SMILES CCC(=O)C(O)=O SMILES N[C@@H](CC(O)=O)C(O)=O Threonine dehydratase biosynthetic, chloroplastic 1.0 1.0 Homoserine kinase CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O HMDB03484 HMDB 5682 ChemSpider CHEBI:30831 ChEBI CHEBI:1146900 ChEBI CHEBI:15699 ChEBI CO-A BioCyc Threonine synthase 1, chloroplastic Probable low-specificity L-threonine aldolase 1 5675 ChemSpider 72-89-9 CAS Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 L-Homoserine 14798-03-9 CAS P46644 UniProt 1.0 Cell Threonine dehydratase biosynthetic, chloroplastic CHEBI:15422 ChEBI Aspartate semialdehyde dehydrogenase Threonine synthase 1, chloroplastic 6557 ChemSpider HMDB00191 HMDB SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 388299 ChemSpider 2-iminobutanoate 1.0 1.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound SMILES [NH4+] 1.0 1.0 CHEBI:16761 ChEBI Q9LYU8 UniProt 1.0 Q1WIQ6 UniProt CHEBI:15428 ChEBI 1.0 133252 ChemSpider O-Phosphohomoserine 2-KETOGLUTARATE BioCyc 392413 ChemSpider 1.0 5893 PubChem-compound HMDB02111 HMDB 439235 PubChem-compound L-Aspartyl-4-phosphate 75-07-0 CAS 172 ChemSpider CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] PW002554 PathWhiz ACETALD BioCyc Acetaldehyde SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Ammonium 5886 PubChem-compound O-Phosphohomoserine C4H8NO7P L-Aspartyl-4-phosphate 213.00385 SMILES CC=O L-Aspartate-semialdehyde L-Aspartyl-4-phosphate CHEBI:30744 ChEBI C4H7NO3 L-Aspartate-semialdehyde 117.042595 1.0 Homoserine kinase HMDB01487 HMDB Aspartate aminotransferase 3, chloroplastic 1.0 CHEBI:15343 ChEBI 16741146 PubChem-compound 388372 ChemSpider 1.0 L-ASPARTATE-SEMIALDEHYDE BioCyc HOMO-SER BioCyc NADP 1061 PubChem-compound HMDB00167 HMDB threonine metabolism 1.0 177 PubChem-compound CHEBI:15351 ChEBI L-Threonine HMDB12250 HMDB 85-61-0 CAS Hydrogen Ion Aspartate semialdehyde dehydrogenase Homoserine kinase Probable low-specificity L-threonine aldolase 1 Methylmalonate- semialdehyde dehydrogenase [acylating], mitochondrial NADP-dependent glyceraldehyde- 3-phosphate dehydrogenase Aspartokinase Aspartate aminotransferase 3, chloroplastic Aspartokinase 1, chloroplastic Aspartokinase 2, chloroplastic Threonine synthase 1, chloroplastic Threonine dehydratase biosynthetic, chloroplastic Acetaldehyde Acetaldehyde L-Aspartyl-4- phosphate NADPH H + P i NADP L-Aspartate- semialdehyde L-Homoserine ATP ADP H + O- Phosphohomoserine L-Threonine Glycine NAD CoA NADH H + Acetyl-CoA CoA NAD NADH H + Acetyl-CoA L-Aspartic acid ATP ADP L-Aspartyl-4- phosphate Oxalacetic acid L-Glutamic acid Oxoglutaric acid H + NADPH NADP L-Homoserine H 2 O P i L-Threonine H + H 2 O (2Z)-2- aminobut-2- enoate 2- iminobutanoate H 2 O H + Ammonium 2-Ketobutyric acid
CHEBI:16015 ChEBI 6022 PubChem-compound C23H38N7O17P3S Acetyl-CoA 809.1258 937 ChemSpider 22138-53-0 CAS Aspartokinase HMDB01341 HMDB NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 439153 PubChem-compound 57 ChemSpider Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial http://identifiers.org/smpdb/SMP02444 SMPDB HMDB12249 HMDB 50 ChemSpider 1.0 Q8RXU4 UniProt HMDB00148 HMDB 809 ChemSpider C00441 KEGG Compound NAD OXALACETIC_ACID BioCyc ATP BioCyc H4N Ammonium 18.034374 1.0 2.0 19796801 PubChem-compound 6288 PubChem-compound 1.0 HMDB01206 HMDB 5745 ChemSpider 5742 ChemSpider L-ASPARTATE BioCyc CHEBI:16474 ChEBI Acetaldehyde ReactionCatalysis7209 ACTIVATION HMDB59597 HMDB GO:0009507 GENE ONTOLOGY 1.0 C4H10NO6P O-Phosphohomoserine 199.02457 HMDB00123 HMDB Aspartokinase 1, chloroplastic Aspartokinase 2, chloroplastic HMDB00005 HMDB threonine deaminase C00109 KEGG Compound Acetyl-CoA 945 ChemSpider P10869 UniProt 1010 ChemSpider Oxoglutaric acid SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS HMDB41827 HMDB Aspartate semialdehyde dehydrogenase 1.0 1.0 HMDB01423 HMDB Hydrogen Ion HMDB00217 HMDB Cytosol Probable low-specificity L-threonine aldolase 1 BiologicalState225 Arabidopsis thaliana, Cell, chloroplast Adenosine triphosphate HMDB00208 HMDB 1.0 L-Aspartate-semialdehyde HMDB00221 HMDB C00009 KEGG Compound C00008 KEGG Compound 1.0 HMDB00223 HMDB Q8VYI4 UniProt C00006 KEGG Compound SMILES N[C@@H](CCOP(O)(O)=O)C(O)=O Q0WM29 UniProt CHEBI:18009 ChEBI C00001 KEGG Compound C00005 KEGG Compound CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound 2-OXOBUTANOATE BioCyc C00002 KEGG Compound HMDB01429 HMDB ReactionCatalysis6301 ACTIVATION Adenosine diphosphate Q9ZSS6 UniProt C21H28N7O14P2 NAD 664.11694 44367445 PubChem-compound 1.0 C01342 KEGG Compound C00010 KEGG Compound C01102 KEGG Compound NAD(P) BioCyc 12126 ChemSpider H Hydrogen Ion 1.007825 SubPathwayInteraction3854 SubPathwayReaction SubPathway3854Reaction C00263 KEGG Compound 56-65-5 CAS SubPathwayInteraction3852 SubPathwayReaction SubPathway3852Reaction 53-84-9 CAS 4.0 SubPathwayInteraction3853 SubPathway3853Reaction SubPathwayReaction C00026 KEGG Compound C00025 KEGG Compound 1.0 C00024 KEGG Compound L-Aspartic acid NADPH SMILES N[C@@H](CC=O)C(O)=O SMILES NC(CC(=O)OP(O)(O)=O)C(O)=O 1.0 Oxalacetic acid 2.0 CL:0000000 CELL TYPE ONTOLOGY 1.0 C00037 KEGG Compound C00036 KEGG Compound L-Homoserine SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 328-50-7 CAS (2Z)-2-aminobut-2-enoate Aspartokinase ReactionCatalysis7266 ACTIVATION 1.0 C00049 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O CHEBI:58739 ChEBI HMDB00538 HMDB ReactionCatalysis7165 ACTIVATION 12647 PubChem-compound SMILES OC(=O)CC(=O)C(O)=O 7732-18-5 CAS 1.0 HMDB00990 HMDB L-BETA-ASPARTYL-P BioCyc 56-86-0 CAS 1.0 4.0 ReactionCatalysis7293 ACTIVATION ReactionCatalysis7292 ACTIVATION ReactionCatalysis7291 ACTIVATION C10H16N5O13P3 Adenosine triphosphate 506.99576 aspartate kinase / homoserine dehydrogenase C00188 KEGG Compound CHEBI:17053 ChEBI 56-40-6 CAS Acetaldehyde ReactionCatalysis7290 ACTIVATION C2H4O Acetaldehyde 44.026215 962 PubChem-compound 151187 PubChem-compound C4H9NO3 L-Threonine 119.05824 PW000940 PathWhiz 5800 ChemSpider SMILES CCC(=N)C([O-])=O Phosphate Phosphate C00080 KEGG Compound 730 ChemSpider 4.2.3.1 false 4.2.3.1 O-Phosphohomoserine + Water → L-Threonine + Phosphate LEFT_TO_RIGHT 2.7.2.4 false 2.7.2.4 Hydrogen Ion + L-Aspartate-semialdehyde + NADPH → L-Homoserine + NADP LEFT_TO_RIGHT C00084 KEGG Compound 15106-57-7 CAS SMILES N[C@@H](CCC(O)=O)C(O)=O 14265-44-2 CAS O23653 UniProt 832 PubChem-compound 58-64-0 CAS 1.0 C4H6O3 2-Ketobutyric acid 102.03169 C4H7NO4 L-Aspartic acid 133.0375 1.0 444493 PubChem-compound 1.0 22833512 PubChem-compound ACETYL-COA BioCyc CHEBI:18051 ChEBI H2O Water 18.010565 SMILES NCC(O)=O 2-Ketobutyric acid NADH BioCyc C4H9NO3 L-Homoserine 119.05824 NAD BioCyc ReactionCatalysis7252 ACTIVATION Transport580 false Acetaldehyde (→) Transport: Arabidopsis thaliana, Cytosol to Arabidopsis thaliana, Cell, Mitochondrion LEFT_TO_RIGHT 56-84-8 CAS L-Threonine 970 PubChem-compound 4.1.2.48 false 4.1.2.48 L-Threonine → Acetaldehyde + Glycine LEFT_TO_RIGHT 1.2.1.4 false 1.2.1.4 Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT Reaction7321 false Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT HMDB00719 HMDB Aspartate kinase 30572 ChemSpider 1.0 17215925 ChemSpider CHEBI:15961 ChEBI O-PHOSPHO-L-HOMOSERINE BioCyc 3702 TAXONOMY C4H4O5 Oxalacetic acid 132.00587 1.0 NADH SMILES N[C@@H](CCO)C(O)=O SMILES O Adenosine triphosphate http://identifiers.org/smpdb/SMP00957 SMPDB 1.0 1.0 6816 PubChem-compound 328-42-7 CAS 51 PubChem-compound CHEBI:15846 ChEBI 2.7.2.4 false 2.7.2.4 Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate LEFT_TO_RIGHT 4.3.1.19 false 4.3.1.19 L-Threonine → (2Z)-2-aminobut-2-enoate + Hydrogen Ion + Water LEFT_TO_RIGHT ADP BioCyc 58 PubChem-compound 53-59-8 CAS Reaction2924 true 2-iminobutanoate + Hydrogen Ion + Water → 2-Ketobutyric acid + Ammonium LEFT_TO_RIGHT THR BioCyc 1.0 1038 PubChem-compound Water GO:0005829 GENE ONTOLOGY C5H6O5 Oxoglutaric acid 146.02153 Reaction2923 true (2Z)-2-aminobut-2-enoate → 2-iminobutanoate LEFT_TO_RIGHT HMDB00902 HMDB CHEBI:16908 ChEBI O4P Phosphate 94.95342 NADPH SMILES CC=C(N)C([O-])=O 1.0 Q8S7B5 UniProt NADP 600-18-0 CAS TCA cycle SubPathway C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 Mitochondrion glycolysis and pyruvate dehydrogenase SubPathway NADPH BioCyc GLY BioCyc CHEBI:16857 ChEBI PW000785 PathWhiz 672-15-1 CAS 218 ChemSpider 58-68-4 CAS 72-19-5 CAS 4210-66-6 CAS SMILES [O-]P([O-])([O-])=O SMILES OC(=O)CCC(=O)C(O)=O CHEBI:30915 ChEBI PW000779 PathWhiz C2H5NO2 Glycine 75.03203 Q8L7R2 UniProt ReactionCatalysis7194 ACTIVATION Aspartokinase 2, chloroplastic Reaction7271 false Hydrogen Ion + L-Aspartyl-4-phosphate + NADPH → L-Aspartate-semialdehyde + NADP + Phosphate LEFT_TO_RIGHT Aspartokinase 1, chloroplastic C4H6NO2 (2Z)-2-aminobut-2-enoate 100.040405 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O L-Glutamic acid 6051 ChemSpider 5257127 PubChem-compound C03082 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O GLT BioCyc 53-57-6 CAS http://identifiers.org/smpdb/SMP00802 SMPDB C4H6NO2 2-iminobutanoate 100.040405 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial CHEBI:28938 ChEBI NADP-dependent glyceraldehyde-3-phosphate dehydrogenase SMILES C[C@@H](O)[C@H](N)C(O)=O http://identifiers.org/smpdb/SMP00807 SMPDB 1.0 C21H29N7O14P2 NADH 665.12476 Glycine 5957 PubChem-compound 2.6.1.1 false 2.6.1.1 L-Glutamic acid + Oxalacetic acid ↔ L-Aspartic acid + Oxoglutaric acid REVERSIBLE 2.7.1.39 false 2.7.1.39 Adenosine triphosphate + L-Homoserine → Adenosine diphosphate + Hydrogen Ion + O-Phosphohomoserine LEFT_TO_RIGHT Aspartate aminotransferase 3, chloroplastic Adenosine diphosphate GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 chloroplast SMILES CCC(=O)C(O)=O SMILES N[C@@H](CC(O)=O)C(O)=O Threonine dehydratase biosynthetic, chloroplastic 1.0 1.0 Homoserine kinase CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O HMDB03484 HMDB 5682 ChemSpider CHEBI:30831 ChEBI CHEBI:1146900 ChEBI CHEBI:15699 ChEBI CO-A BioCyc Threonine synthase 1, chloroplastic Probable low-specificity L-threonine aldolase 1 5675 ChemSpider 72-89-9 CAS Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 L-Homoserine 14798-03-9 CAS P46644 UniProt 1.0 Cell Threonine dehydratase biosynthetic, chloroplastic CHEBI:15422 ChEBI Aspartate semialdehyde dehydrogenase Threonine synthase 1, chloroplastic 6557 ChemSpider HMDB00191 HMDB SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 388299 ChemSpider 2-iminobutanoate 1.0 1.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound SMILES [NH4+] 1.0 1.0 CHEBI:16761 ChEBI Q9LYU8 UniProt 1.0 Q1WIQ6 UniProt CHEBI:15428 ChEBI 1.0 133252 ChemSpider propanoate metabolism SubPathway O-Phosphohomoserine 2-KETOGLUTARATE BioCyc 392413 ChemSpider 1.0 5893 PubChem-compound HMDB02111 HMDB 439235 PubChem-compound L-Aspartyl-4-phosphate 75-07-0 CAS 172 ChemSpider CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] PW002554 PathWhiz ACETALD BioCyc Acetaldehyde SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Ammonium 5886 PubChem-compound O-Phosphohomoserine C4H8NO7P L-Aspartyl-4-phosphate 213.00385 SMILES CC=O L-Aspartate-semialdehyde L-Aspartyl-4-phosphate CHEBI:30744 ChEBI C4H7NO3 L-Aspartate-semialdehyde 117.042595 1.0 Homoserine kinase HMDB01487 HMDB Aspartate aminotransferase 3, chloroplastic 1.0 CHEBI:15343 ChEBI 16741146 PubChem-compound 388372 ChemSpider 1.0 L-ASPARTATE-SEMIALDEHYDE BioCyc HOMO-SER BioCyc NADP 1061 PubChem-compound HMDB00167 HMDB threonine metabolism 1.0 177 PubChem-compound CHEBI:15351 ChEBI L-Threonine HMDB12250 HMDB 85-61-0 CAS Hydrogen Ion Mitochondria Unknown Unknown THA1 ALDH6B2 ALDH11A3 HOM3 ASP3 AK1 AK2