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Tirofiban is a platelet aggregation inhibitor, also known under the brand name Aggrastat, it is used to prevent thrombotic events from occurring in those who are high-risk. It is administered intravenously and acts as an antagonist of the platelet glycoprotein IIb/IIIa receptor, this receptor is responsible for platelet aggregation in order to form a thrombus, without this signal from the receptor it stops aggregation. This inhibition created by the drug will cease once the drug is no longer infused into the patient's bloodstream.

Tirofiban is a platelet aggregation inhibitor drug sold under the name Aggrastat. It is specifically a small molecule that inhibits the glycoprotein IIb/IIIa receptor of platelets. It is administered intravenously, and can act to decrease platelet aggregation by over 90% after the infusion, and can help prevent aggregation for up to two days after administration. In the vein, tirofiban causes a conformational change in the integrins on the surface of activated platelets. This prevents the binding of fibrinogen to these integrins, which in turn prevents the platelets from being held together by these fibrinogen fibres. The conformational change also prevents the binding of von Willebrand factor to the platelets, which also prevents aggregation and adhesion.